AR052028A1 - Medio de cultivo de celula libre de suero para las celulas de los mamiferos - Google Patents
Medio de cultivo de celula libre de suero para las celulas de los mamiferosInfo
- Publication number
- AR052028A1 AR052028A1 ARP050104563A AR052028A1 AR 052028 A1 AR052028 A1 AR 052028A1 AR P050104563 A ARP050104563 A AR P050104563A AR 052028 A1 AR052028 A1 AR 052028A1
- Authority
- AR
- Argentina
- Prior art keywords
- cell culture
- growing
- free cell
- culture media
- mammals cells
- Prior art date
Links
- 239000006143 cell culture medium Substances 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 title 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 239000012679 serum free medium Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/825—Metallothioneins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0043—Medium free of human- or animal-derived components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/005—Protein-free medium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/22—Zinc; Zn chelators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente se refiere a un medio de cultivo de célula libre de suero para las células de mamífero. Las células cultivadas con el medio libre de suero de la presente son particularmente utiles para la produccion de las proteínas recombinantes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04105451 | 2004-11-02 | ||
US62488504P | 2004-11-04 | 2004-11-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR052028A1 true AR052028A1 (es) | 2007-02-28 |
Family
ID=34981827
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP050104563 AR052028A1 (es) | 2004-11-02 | 2005-11-01 | Medio de cultivo de celula libre de suero para las celulas de los mamiferos |
Country Status (20)
Country | Link |
---|---|
US (1) | US7709229B2 (es) |
EP (1) | EP1807504B1 (es) |
JP (1) | JP4833991B2 (es) |
KR (1) | KR101196103B1 (es) |
CN (1) | CN101052708B (es) |
AR (1) | AR052028A1 (es) |
AT (1) | ATE499434T1 (es) |
AU (1) | AU2005330353B2 (es) |
CA (1) | CA2583027A1 (es) |
DE (1) | DE602005026548D1 (es) |
DK (1) | DK1807504T3 (es) |
ES (1) | ES2361559T3 (es) |
NO (1) | NO341236B1 (es) |
PL (1) | PL1807504T3 (es) |
PT (1) | PT1807504E (es) |
RS (1) | RS51913B (es) |
SI (1) | SI1807504T1 (es) |
UA (1) | UA92157C2 (es) |
WO (1) | WO2006108455A1 (es) |
ZA (1) | ZA200702434B (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2009132986A (ru) * | 2007-03-02 | 2011-04-10 | Уайт (Us) | Применение меди и глутамата в культуре клеток для производства полипептидов |
US20110137012A1 (en) | 2007-04-26 | 2011-06-09 | Chugai Seiyaku Kabushiki Kaisha | Cell culture method using amino acid-enriched medium |
CN101386837B (zh) * | 2007-09-12 | 2011-06-29 | 北京清大天一科技有限公司 | 一种动物细胞培养方法 |
CN107090481A (zh) * | 2008-04-17 | 2017-08-25 | 惠氏有限责任公司 | 提高骨形成蛋白产量的方法 |
CN105331659B (zh) * | 2010-04-26 | 2019-07-16 | 诺华股份有限公司 | 改进的细胞培养基 |
CN102234627B (zh) * | 2010-04-30 | 2015-06-03 | 中国科学院广州生物医药与健康研究院 | 一种培养基添加剂及其应用 |
US9458222B2 (en) | 2010-07-08 | 2016-10-04 | Baxalta Incorporated | Method of producing recombinant ADAMTS13 in cell culture |
PL2702164T3 (pl) | 2011-04-29 | 2016-06-30 | Biocon Res Limited | Sposób obniżania heterogeniczności przeciwciał i sposób ich wytwarzania |
EA201490945A1 (ru) | 2011-11-11 | 2014-08-29 | ЭССЕНШЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Набор, содержащий заменитель сыворотки и лабильные факторы |
SG11201507577RA (en) | 2013-03-15 | 2015-10-29 | Janssen Biotech Inc | Manufacturing methods to control c-terminal lysine, galactose and sialic acid content in recombinant proteins |
USD752616S1 (en) * | 2013-10-23 | 2016-03-29 | Ares Trading S.A. | Display screen with graphical user interface |
EP3083978A4 (en) | 2013-12-20 | 2017-08-30 | Bio-Ess Laboratories, LLC | Media for cell culture |
SG11201606856SA (en) * | 2014-02-27 | 2016-09-29 | Hoffmann La Roche | Modulation of cell growth and glycosylation in recombinant glycoprotein production |
USD779505S1 (en) | 2014-11-14 | 2017-02-21 | Dexcom, Inc. | Display screen or portion thereof with graphical user interface for analyte data presentation |
USD779504S1 (en) * | 2014-11-14 | 2017-02-21 | Dexcom, Inc. | Display screen or portion thereof with graphical user interface for presentation of analyte data |
KR101867134B1 (ko) * | 2015-03-23 | 2018-06-12 | 한양대학교 산학협력단 | 포유류 세포를 이용하여 목적 물질을 고효율로 생산하기 위한 세포 배양 배지, 이를 이용한 세포 배양 방법 및 목적 물질의 생산 방법 |
RU2018137547A (ru) * | 2016-03-31 | 2020-04-30 | Санбио, Инк. | Среда, способы, клетки и секретируемые факторы для культуры стволовых клеток и терапии |
CN110042137B (zh) * | 2019-05-14 | 2023-02-28 | 上海赛迈生物科技有限公司 | 高密度灌注培养重组cho细胞生产人促卵泡激素的方法、培养基及其应用 |
CN114075540B (zh) * | 2020-08-21 | 2023-10-13 | 苏州新微溪生物医药有限公司 | 全化学成分hek293细胞培养基及其应用 |
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US4579821A (en) * | 1981-11-23 | 1986-04-01 | University Patents, Inc. | Control of DNA sequence transcription |
JPS60500358A (ja) * | 1982-12-23 | 1985-03-22 | アメリカ合衆国 | マウスの細胞内で組み換えdnaによって生産されたヒト成長ホルモン |
US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
DE3688418T2 (de) * | 1985-02-13 | 1993-08-26 | Scios Nova Inc | Menschlicher metallothionein ii-promotor in saeugetierexpressionssystemen. |
US4935350A (en) * | 1985-11-18 | 1990-06-19 | Amgen | Materials and methods for controlling plasmid copy number and stability |
CS262822B1 (en) * | 1986-10-03 | 1989-04-14 | Kovar Jan | Synthetic medium for the cultivation of myelomic cells |
US5045468A (en) | 1986-12-12 | 1991-09-03 | Cell Enterprises, Inc. | Protein-free culture medium which promotes hybridoma growth |
NO162160C (no) | 1987-01-09 | 1989-11-15 | Medi Cult As | Serumfritt vekstmedium, samt anvendelse derav. |
NZ226414A (en) | 1987-10-02 | 1992-07-28 | Genentech Inc | Cd4 peptide adhesion variants and their preparation and use |
EP1762623A1 (en) | 1988-01-22 | 2007-03-14 | ZymoGenetics, Inc. | Methods for producing biologically active peptide dimers |
US6048728A (en) * | 1988-09-23 | 2000-04-11 | Chiron Corporation | Cell culture medium for enhanced cell growth, culture longevity, and product expression |
US5143842A (en) | 1988-11-01 | 1992-09-01 | The University Of Colorado Foundation, Inc. | Media for normal human muscle satellite cells |
NO894143D0 (no) * | 1988-11-18 | 1989-10-17 | Phillips Petroleum Co | Bovinmetallotionein-regulatorisk omraade. |
US5834312A (en) * | 1990-01-29 | 1998-11-10 | Hy-Gene, Inc. | Process and media for the growth of human epithelia |
JP3008208B2 (ja) * | 1990-06-01 | 2000-02-14 | 武田薬品工業株式会社 | 新規ハイブリドーマ,その製造法および生理活性物質の製造法 |
US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
GB9022545D0 (en) * | 1990-10-17 | 1990-11-28 | Wellcome Found | Culture medium |
EP0666312A1 (en) | 1994-02-08 | 1995-08-09 | Wolfgang A. Renner | Process for the improvement of mammalian cell growth |
PT802257E (pt) | 1996-04-19 | 2003-01-31 | Nestle Sa | Linhagem imortalizada de celulas epiteliais do colon humano |
EP2221361A3 (en) * | 1996-08-30 | 2011-02-09 | Life Technologies Corporation | Method for producing a polypeptide in vitro in mammalian cells in a protein-free and serum-free culture medium |
JP4543402B2 (ja) * | 1996-10-10 | 2010-09-15 | ライフ テクノロジーズ コーポレーション | 植物由来栄養素を含む動物細胞培養培地 |
US20030153042A1 (en) | 1998-07-28 | 2003-08-14 | California Institute Of Technology | Expression of functional eukaryotic proteins |
AU7081500A (en) | 1999-08-27 | 2001-03-26 | Invitrogen Corporation | Metal binding compounds and their use in cell culture medium compositions |
EP1360314B1 (en) * | 2001-02-15 | 2009-01-14 | Centocor, Inc. | Chemically defined medium for cultured mammalian cells |
US20030096414A1 (en) | 2001-03-27 | 2003-05-22 | Invitrogen Corporation | Culture medium for cell growth and transfection |
-
2005
- 2005-10-28 ZA ZA200702434A patent/ZA200702434B/xx unknown
- 2005-10-28 KR KR20077008456A patent/KR101196103B1/ko active IP Right Grant
- 2005-10-28 EP EP05857769A patent/EP1807504B1/en active Active
- 2005-10-28 SI SI200531258T patent/SI1807504T1/sl unknown
- 2005-10-28 PT PT05857769T patent/PT1807504E/pt unknown
- 2005-10-28 WO PCT/EP2005/055637 patent/WO2006108455A1/en active Application Filing
- 2005-10-28 CA CA 2583027 patent/CA2583027A1/en not_active Abandoned
- 2005-10-28 RS RSP20110137 patent/RS51913B/en unknown
- 2005-10-28 PL PL05857769T patent/PL1807504T3/pl unknown
- 2005-10-28 UA UAA200706101A patent/UA92157C2/ru unknown
- 2005-10-28 ES ES05857769T patent/ES2361559T3/es active Active
- 2005-10-28 JP JP2007538432A patent/JP4833991B2/ja active Active
- 2005-10-28 CN CN2005800376023A patent/CN101052708B/zh active Active
- 2005-10-28 US US11/576,277 patent/US7709229B2/en active Active
- 2005-10-28 AT AT05857769T patent/ATE499434T1/de active
- 2005-10-28 DK DK05857769T patent/DK1807504T3/da active
- 2005-10-28 DE DE200560026548 patent/DE602005026548D1/de active Active
- 2005-10-28 AU AU2005330353A patent/AU2005330353B2/en active Active
- 2005-11-01 AR ARP050104563 patent/AR052028A1/es active IP Right Grant
-
2007
- 2007-05-29 NO NO20072719A patent/NO341236B1/no unknown
Also Published As
Publication number | Publication date |
---|---|
CA2583027A1 (en) | 2006-10-19 |
US20080064644A1 (en) | 2008-03-13 |
CN101052708A (zh) | 2007-10-10 |
JP2008518592A (ja) | 2008-06-05 |
CN101052708B (zh) | 2012-08-29 |
RS51913B (en) | 2012-02-29 |
KR20070073780A (ko) | 2007-07-10 |
AU2005330353A1 (en) | 2006-10-19 |
JP4833991B2 (ja) | 2011-12-07 |
DK1807504T3 (da) | 2011-03-21 |
PT1807504E (pt) | 2011-03-07 |
US7709229B2 (en) | 2010-05-04 |
EP1807504A1 (en) | 2007-07-18 |
ZA200702434B (en) | 2008-08-27 |
SI1807504T1 (sl) | 2011-05-31 |
WO2006108455A1 (en) | 2006-10-19 |
DE602005026548D1 (de) | 2011-04-07 |
EP1807504B1 (en) | 2011-02-23 |
ATE499434T1 (de) | 2011-03-15 |
ES2361559T3 (es) | 2011-06-20 |
NO341236B1 (no) | 2017-09-25 |
NO20072719L (no) | 2007-05-29 |
AU2005330353B2 (en) | 2010-10-14 |
KR101196103B1 (ko) | 2012-11-01 |
UA92157C2 (ru) | 2010-10-11 |
PL1807504T3 (pl) | 2011-07-29 |
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