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UA92157C2 - Способ продуцирования гормона роста - Google Patents

Способ продуцирования гормона роста

Info

Publication number
UA92157C2
UA92157C2 UAA200706101A UAA200706101A UA92157C2 UA 92157 C2 UA92157 C2 UA 92157C2 UA A200706101 A UAA200706101 A UA A200706101A UA A200706101 A UAA200706101 A UA A200706101A UA 92157 C2 UA92157 C2 UA 92157C2
Authority
UA
Ukraine
Prior art keywords
production
growth hormone
cultivated
culture
medium
Prior art date
Application number
UAA200706101A
Other languages
English (en)
Ukrainian (uk)
Inventor
Эрнандес Хосе Касаторрес
Пьера Карлос Мартин
Original Assignee
Арес Трейдинг С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Арес Трейдинг С.А. filed Critical Арес Трейдинг С.А.
Publication of UA92157C2 publication Critical patent/UA92157C2/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/825—Metallothioneins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0043—Medium free of human- or animal-derived components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/005—Protein-free medium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/22—Zinc; Zn chelators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/36—Lipids
    • C—CHEMISTRY; METALLURGY
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Изобретение относится к способу производства гормона роста в культуре клеток млекопитающих, которые культивируются в среде, не содержащей сыворотки.
UAA200706101A 2004-11-02 2005-10-28 Способ продуцирования гормона роста UA92157C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04105451 2004-11-02

Publications (1)

Publication Number Publication Date
UA92157C2 true UA92157C2 (ru) 2010-10-11

Family

ID=34981827

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200706101A UA92157C2 (ru) 2004-11-02 2005-10-28 Способ продуцирования гормона роста

Country Status (20)

Country Link
US (1) US7709229B2 (ru)
EP (1) EP1807504B1 (ru)
JP (1) JP4833991B2 (ru)
KR (1) KR101196103B1 (ru)
CN (1) CN101052708B (ru)
AR (1) AR052028A1 (ru)
AT (1) ATE499434T1 (ru)
AU (1) AU2005330353B2 (ru)
CA (1) CA2583027A1 (ru)
DE (1) DE602005026548D1 (ru)
DK (1) DK1807504T3 (ru)
ES (1) ES2361559T3 (ru)
NO (1) NO341236B1 (ru)
PL (1) PL1807504T3 (ru)
PT (1) PT1807504E (ru)
RS (1) RS51913B (ru)
SI (1) SI1807504T1 (ru)
UA (1) UA92157C2 (ru)
WO (1) WO2006108455A1 (ru)
ZA (1) ZA200702434B (ru)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009009240A (es) * 2007-03-02 2009-09-08 Wyeth Corp Uso de cobre y glutamato en el cultivo celular para la produccion de polipeptidos.
ES2624185T3 (es) 2007-04-26 2017-07-13 Chugai Seiyaku Kabushiki Kaisha Método de cultivo celular que utiliza un medio enriquecido con aminoácidos
CN101386837B (zh) * 2007-09-12 2011-06-29 北京清大天一科技有限公司 一种动物细胞培养方法
KR101286895B1 (ko) * 2008-04-17 2013-07-16 와이어쓰 엘엘씨 골 형태발생 단백질의 개선된 생산 방법
JP6113653B2 (ja) * 2010-04-26 2017-04-12 ノバルティス アーゲー 改良型細胞培養培地
CN102234627B (zh) * 2010-04-30 2015-06-03 中国科学院广州生物医药与健康研究院 一种培养基添加剂及其应用
HUE11738351T2 (hu) 2010-07-08 2019-03-28 Baxalta GmbH Eljárás rekombináns ADAMTS13 elõállítására sejttenyészetben
US9631216B2 (en) * 2011-04-29 2017-04-25 Biocon Research Limited Method for reducing heterogeneity of antibodies and a process of producing the antibodies thereof
AU2012335070A1 (en) 2011-11-11 2014-05-29 Bio-Ess Laboratories, Llc Kit comprising serum replacement and labile factors
SMT201800550T1 (it) 2013-03-15 2019-01-11 Janssen Biotech Inc Metodi di fabbricazione per regolare il contenuto di lisina c-terminale,galattosio e acido sialico in proteine combinanti
USD753140S1 (en) * 2013-10-23 2016-04-05 Ares Trading S.A. Display screen with graphical user interface
AU2014364368A1 (en) 2013-12-20 2016-07-07 Bio-Ess Laboratories, Llc Media for cell culture
BR112016017660B1 (pt) * 2014-02-27 2022-04-19 F. Hoffmann-La Roche Ag Método para a produção de uma glicoproteína recombinante
USD779505S1 (en) 2014-11-14 2017-02-21 Dexcom, Inc. Display screen or portion thereof with graphical user interface for analyte data presentation
USD779504S1 (en) * 2014-11-14 2017-02-21 Dexcom, Inc. Display screen or portion thereof with graphical user interface for presentation of analyte data
KR101867134B1 (ko) * 2015-03-23 2018-06-12 한양대학교 산학협력단 포유류 세포를 이용하여 목적 물질을 고효율로 생산하기 위한 세포 배양 배지, 이를 이용한 세포 배양 방법 및 목적 물질의 생산 방법
CN109219658A (zh) * 2016-03-31 2019-01-15 赛百奥公司 用于干细胞培养和治疗的培养基、方法、细胞和分泌的因子
CN110042137B (zh) * 2019-05-14 2023-02-28 上海赛迈生物科技有限公司 高密度灌注培养重组cho细胞生产人促卵泡激素的方法、培养基及其应用
CN114075540B (zh) * 2020-08-21 2023-10-13 苏州新微溪生物医药有限公司 全化学成分hek293细胞培养基及其应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579821A (en) * 1981-11-23 1986-04-01 University Patents, Inc. Control of DNA sequence transcription
CA1224168A (en) * 1982-12-23 1987-07-14 Dean H. Hamer Human growth hormone produced by recombinant dna in mouse cells
US4767704A (en) * 1983-10-07 1988-08-30 Columbia University In The City Of New York Protein-free culture medium
AU580145B2 (en) * 1985-02-13 1989-01-05 Scios Nova Inc. Human metallothionein-ii promoter in mammalian expression system
US4935350A (en) * 1985-11-18 1990-06-19 Amgen Materials and methods for controlling plasmid copy number and stability
CS262822B1 (en) * 1986-10-03 1989-04-14 Kovar Jan Synthetic medium for the cultivation of myelomic cells
US5045468A (en) 1986-12-12 1991-09-03 Cell Enterprises, Inc. Protein-free culture medium which promotes hybridoma growth
NO162160C (no) 1987-01-09 1989-11-15 Medi Cult As Serumfritt vekstmedium, samt anvendelse derav.
NZ226414A (en) 1987-10-02 1992-07-28 Genentech Inc Cd4 peptide adhesion variants and their preparation and use
ATE140963T1 (de) 1988-01-22 1996-08-15 Zymogenetics Inc Verfahren zur herstellung von sekretierten rezeptoranalogen
US6048728A (en) * 1988-09-23 2000-04-11 Chiron Corporation Cell culture medium for enhanced cell growth, culture longevity, and product expression
US5143842A (en) * 1988-11-01 1992-09-01 The University Of Colorado Foundation, Inc. Media for normal human muscle satellite cells
NO894143D0 (no) * 1988-11-18 1989-10-17 Phillips Petroleum Co Bovinmetallotionein-regulatorisk omraade.
US5834312A (en) * 1990-01-29 1998-11-10 Hy-Gene, Inc. Process and media for the growth of human epithelia
JP3008208B2 (ja) * 1990-06-01 2000-02-14 武田薬品工業株式会社 新規ハイブリドーマ，その製造法および生理活性物質の製造法
US5122469A (en) * 1990-10-03 1992-06-16 Genentech, Inc. Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
GB9022545D0 (en) 1990-10-17 1990-11-28 Wellcome Found Culture medium
EP0666312A1 (en) 1994-02-08 1995-08-09 Wolfgang A. Renner Process for the improvement of mammalian cell growth
PT802257E (pt) 1996-04-19 2003-01-31 Nestle Sa Linhagem imortalizada de celulas epiteliais do colon humano
EP2218775B1 (en) * 1996-08-30 2015-01-28 Life Technologies Corporation Method for producing a polypeptide in vitro in mammalian cells in a protein-free and serum-free culture medium
EP1983044B1 (en) * 1996-10-10 2016-08-10 Life Technologies Corporation Animal cell culture media comprising plant-derived nutrients
US20030153042A1 (en) 1998-07-28 2003-08-14 California Institute Of Technology Expression of functional eukaryotic proteins
CA2383460C (en) 1999-08-27 2015-10-13 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
ATE420945T1 (de) 2001-02-15 2009-01-15 Centocor Inc Chemisch definiertes medium für kultivierte säugerzellen
US20030096414A1 (en) 2001-03-27 2003-05-22 Invitrogen Corporation Culture medium for cell growth and transfection

Also Published As

Publication number Publication date
SI1807504T1 (sl) 2011-05-31
JP2008518592A (ja) 2008-06-05
PT1807504E (pt) 2011-03-07
DE602005026548D1 (de) 2011-04-07
PL1807504T3 (pl) 2011-07-29
US20080064644A1 (en) 2008-03-13
NO341236B1 (no) 2017-09-25
CA2583027A1 (en) 2006-10-19
ZA200702434B (en) 2008-08-27
US7709229B2 (en) 2010-05-04
AU2005330353A1 (en) 2006-10-19
DK1807504T3 (da) 2011-03-21
KR101196103B1 (ko) 2012-11-01
ATE499434T1 (de) 2011-03-15
ES2361559T3 (es) 2011-06-20
AU2005330353B2 (en) 2010-10-14
AR052028A1 (es) 2007-02-28
JP4833991B2 (ja) 2011-12-07
CN101052708B (zh) 2012-08-29
WO2006108455A1 (en) 2006-10-19
NO20072719L (no) 2007-05-29
CN101052708A (zh) 2007-10-10
RS51913B (en) 2012-02-29
EP1807504B1 (en) 2011-02-23
EP1807504A1 (en) 2007-07-18
KR20070073780A (ko) 2007-07-10

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