DE602005026548D1 - Serumfreies kulturmedium für säugerzellen - Google Patents
Serumfreies kulturmedium für säugerzellenInfo
- Publication number
- DE602005026548D1 DE602005026548D1 DE200560026548 DE602005026548T DE602005026548D1 DE 602005026548 D1 DE602005026548 D1 DE 602005026548D1 DE 200560026548 DE200560026548 DE 200560026548 DE 602005026548 T DE602005026548 T DE 602005026548T DE 602005026548 D1 DE602005026548 D1 DE 602005026548D1
- Authority
- DE
- Germany
- Prior art keywords
- serum
- culture medium
- mammalian cells
- free culture
- free
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000004962 mammalian cell Anatomy 0.000 title 1
- 239000004017 serum-free culture medium Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/825—Metallothioneins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0043—Medium free of human- or animal-derived components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/005—Protein-free medium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/22—Zinc; Zn chelators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04105451 | 2004-11-02 | ||
| US62488504P | 2004-11-04 | 2004-11-04 | |
| PCT/EP2005/055637 WO2006108455A1 (en) | 2004-11-02 | 2005-10-28 | Serum-free cell culture medium for mammalian cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602005026548D1 true DE602005026548D1 (de) | 2011-04-07 |
Family
ID=34981827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE200560026548 Active DE602005026548D1 (de) | 2004-11-02 | 2005-10-28 | Serumfreies kulturmedium für säugerzellen |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7709229B2 (de) |
| EP (1) | EP1807504B1 (de) |
| JP (1) | JP4833991B2 (de) |
| KR (1) | KR101196103B1 (de) |
| CN (1) | CN101052708B (de) |
| AR (1) | AR052028A1 (de) |
| AT (1) | ATE499434T1 (de) |
| AU (1) | AU2005330353B2 (de) |
| CA (1) | CA2583027A1 (de) |
| DE (1) | DE602005026548D1 (de) |
| DK (1) | DK1807504T3 (de) |
| ES (1) | ES2361559T3 (de) |
| NO (1) | NO341236B1 (de) |
| PL (1) | PL1807504T3 (de) |
| PT (1) | PT1807504E (de) |
| RS (1) | RS51913B (de) |
| SI (1) | SI1807504T1 (de) |
| UA (1) | UA92157C2 (de) |
| WO (1) | WO2006108455A1 (de) |
| ZA (1) | ZA200702434B (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2115126E (pt) | 2007-03-02 | 2015-08-24 | Wyeth Llc | Utilização de cobre e glutamato na cultura de células para a produção de polipeptídeos |
| EP2154244B1 (de) | 2007-04-26 | 2017-04-12 | Chugai Seiyaku Kabushiki Kaisha | Zellkulturverfahren unter verwendung von mit aminosäuren angereichertem medium |
| CN101386837B (zh) * | 2007-09-12 | 2011-06-29 | 北京清大天一科技有限公司 | 一种动物细胞培养方法 |
| CN102037132A (zh) * | 2008-04-17 | 2011-04-27 | 惠氏有限责任公司 | 提高骨形成蛋白产量的方法 |
| EP3599276A1 (de) * | 2010-04-26 | 2020-01-29 | Novartis AG | Verbessertes zellkulturmedium |
| CN102234627B (zh) * | 2010-04-30 | 2015-06-03 | 中国科学院广州生物医药与健康研究院 | 一种培养基添加剂及其应用 |
| CN108060154A (zh) | 2010-07-08 | 2018-05-22 | 百深有限责任公司 | 在细胞培养物中生产重组adamts13的方法 |
| DK2702164T3 (en) * | 2011-04-29 | 2016-02-01 | Biocon Res Ltd | METHOD FOR REDUCING heterogeneity OF ANTIBODIES AND METHOD OF PRODUCING THESE ANTIBODIES |
| MX2014005723A (es) | 2011-11-11 | 2014-11-25 | Essential Pharmaceuticals Llc | Kit que comprende factores labiles y de reemplazo de suero. |
| AU2014237635B2 (en) * | 2013-03-15 | 2020-03-12 | Janssen Biologics B.V. | Manufacturing methods to control C-terminal lysine, galactose and sialic acid content in recombinant proteins |
| USD757071S1 (en) * | 2013-10-23 | 2016-05-24 | Ares Trading S.A. | Display screen with graphical user interface |
| US9637721B2 (en) | 2013-12-20 | 2017-05-02 | Bio-Ess Laboratories, Llc. | Media for cell culture |
| LT3110961T (lt) * | 2014-02-27 | 2020-02-10 | F. Hoffmann-La Roche Ag | Ląstelių augimo ir glikozilinimo moduliavimas, gaminant rekombinantinį glikoproteiną |
| USD779505S1 (en) | 2014-11-14 | 2017-02-21 | Dexcom, Inc. | Display screen or portion thereof with graphical user interface for analyte data presentation |
| USD779504S1 (en) * | 2014-11-14 | 2017-02-21 | Dexcom, Inc. | Display screen or portion thereof with graphical user interface for presentation of analyte data |
| KR101867134B1 (ko) * | 2015-03-23 | 2018-06-12 | 한양대학교 산학협력단 | 포유류 세포를 이용하여 목적 물질을 고효율로 생산하기 위한 세포 배양 배지, 이를 이용한 세포 배양 방법 및 목적 물질의 생산 방법 |
| KR102705670B1 (ko) * | 2016-03-31 | 2024-09-11 | 샌바이오, 인크. | 줄기 세포 배양 및 치료를 위한 배지, 방법, 세포 및 분비 인자 |
| CN110042137B (zh) * | 2019-05-14 | 2023-02-28 | 上海赛迈生物科技有限公司 | 高密度灌注培养重组cho细胞生产人促卵泡激素的方法、培养基及其应用 |
| CN114075540B (zh) * | 2020-08-21 | 2023-10-13 | 苏州新微溪生物医药有限公司 | 全化学成分hek293细胞培养基及其应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4579821A (en) * | 1981-11-23 | 1986-04-01 | University Patents, Inc. | Control of DNA sequence transcription |
| CA1224168A (en) * | 1982-12-23 | 1987-07-14 | Dean H. Hamer | Human growth hormone produced by recombinant dna in mouse cells |
| US4767704A (en) * | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| AU580145B2 (en) * | 1985-02-13 | 1989-01-05 | Scios Nova Inc. | Human metallothionein-ii promoter in mammalian expression system |
| US4935350A (en) * | 1985-11-18 | 1990-06-19 | Amgen | Materials and methods for controlling plasmid copy number and stability |
| CS262822B1 (en) * | 1986-10-03 | 1989-04-14 | Kovar Jan | Synthetic medium for the cultivation of myelomic cells |
| US5045468A (en) | 1986-12-12 | 1991-09-03 | Cell Enterprises, Inc. | Protein-free culture medium which promotes hybridoma growth |
| NO162160C (no) | 1987-01-09 | 1989-11-15 | Medi Cult As | Serumfritt vekstmedium, samt anvendelse derav. |
| NZ226414A (en) | 1987-10-02 | 1992-07-28 | Genentech Inc | Cd4 peptide adhesion variants and their preparation and use |
| ES2092468T3 (es) | 1988-01-22 | 1996-12-01 | Zymogenetics Inc | Metodos para producir analogos de receptores secretados. |
| US6048728A (en) | 1988-09-23 | 2000-04-11 | Chiron Corporation | Cell culture medium for enhanced cell growth, culture longevity, and product expression |
| US5143842A (en) | 1988-11-01 | 1992-09-01 | The University Of Colorado Foundation, Inc. | Media for normal human muscle satellite cells |
| NO894143D0 (no) * | 1988-11-18 | 1989-10-17 | Phillips Petroleum Co | Bovinmetallotionein-regulatorisk omraade. |
| US5834312A (en) | 1990-01-29 | 1998-11-10 | Hy-Gene, Inc. | Process and media for the growth of human epithelia |
| JP3008208B2 (ja) * | 1990-06-01 | 2000-02-14 | 武田薬品工業株式会社 | 新規ハイブリドーマ，その製造法および生理活性物質の製造法 |
| US5122469A (en) | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| GB9022545D0 (en) * | 1990-10-17 | 1990-11-28 | Wellcome Found | Culture medium |
| EP0666312A1 (de) | 1994-02-08 | 1995-08-09 | Wolfgang A. Renner | Verfahren zur Förderung des Wachstums von Säugetierzellen |
| ATE222598T1 (de) | 1996-04-19 | 2002-09-15 | Nestle Sa | Menschliche immortalisierte colon- epithelialzellen |
| EP2218775B1 (de) * | 1996-08-30 | 2015-01-28 | Life Technologies Corporation | Methode zur Herstellung eines Polypeptids in vitro in einer Säugerzelle in einem Kulturmedium ohne Serum und ohne Proteine |
| EP1983044B1 (de) * | 1996-10-10 | 2016-08-10 | Life Technologies Corporation | Tierzellkulturmedien mit Nährstoffen aus Pflanzen |
| US20030153042A1 (en) | 1998-07-28 | 2003-08-14 | California Institute Of Technology | Expression of functional eukaryotic proteins |
| CA2383460C (en) | 1999-08-27 | 2015-10-13 | Invitrogen Corporation | Metal binding compounds and their use in cell culture medium compositions |
| JP2005505240A (ja) * | 2001-02-15 | 2005-02-24 | セントカー・インコーポレーテツド | 培養された哺乳動物細胞のための化学的合成培地 |
| US20030096414A1 (en) | 2001-03-27 | 2003-05-22 | Invitrogen Corporation | Culture medium for cell growth and transfection |
-
2005
- 2005-10-28 KR KR20077008456A patent/KR101196103B1/ko active Active
- 2005-10-28 UA UAA200706101A patent/UA92157C2/ru unknown
- 2005-10-28 SI SI200531258T patent/SI1807504T1/sl unknown
- 2005-10-28 ES ES05857769T patent/ES2361559T3/es active Active
- 2005-10-28 US US11/576,277 patent/US7709229B2/en active Active
- 2005-10-28 ZA ZA200702434A patent/ZA200702434B/xx unknown
- 2005-10-28 JP JP2007538432A patent/JP4833991B2/ja active Active
- 2005-10-28 DK DK05857769T patent/DK1807504T3/da active
- 2005-10-28 PT PT05857769T patent/PT1807504E/pt unknown
- 2005-10-28 WO PCT/EP2005/055637 patent/WO2006108455A1/en active Application Filing
- 2005-10-28 RS RSP20110137 patent/RS51913B/en unknown
- 2005-10-28 AT AT05857769T patent/ATE499434T1/de active
- 2005-10-28 EP EP05857769A patent/EP1807504B1/de active Active
- 2005-10-28 CA CA 2583027 patent/CA2583027A1/en not_active Abandoned
- 2005-10-28 AU AU2005330353A patent/AU2005330353B2/en active Active
- 2005-10-28 DE DE200560026548 patent/DE602005026548D1/de active Active
- 2005-10-28 PL PL05857769T patent/PL1807504T3/pl unknown
- 2005-10-28 CN CN2005800376023A patent/CN101052708B/zh active Active
- 2005-11-01 AR ARP050104563 patent/AR052028A1/es active IP Right Grant
-
2007
- 2007-05-29 NO NO20072719A patent/NO341236B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20070073780A (ko) | 2007-07-10 |
| KR101196103B1 (ko) | 2012-11-01 |
| JP2008518592A (ja) | 2008-06-05 |
| AU2005330353A1 (en) | 2006-10-19 |
| ATE499434T1 (de) | 2011-03-15 |
| UA92157C2 (ru) | 2010-10-11 |
| CN101052708A (zh) | 2007-10-10 |
| US7709229B2 (en) | 2010-05-04 |
| NO341236B1 (no) | 2017-09-25 |
| EP1807504A1 (de) | 2007-07-18 |
| PL1807504T3 (pl) | 2011-07-29 |
| SI1807504T1 (sl) | 2011-05-31 |
| RS51913B (en) | 2012-02-29 |
| CA2583027A1 (en) | 2006-10-19 |
| AR052028A1 (es) | 2007-02-28 |
| ES2361559T3 (es) | 2011-06-20 |
| US20080064644A1 (en) | 2008-03-13 |
| ZA200702434B (en) | 2008-08-27 |
| WO2006108455A1 (en) | 2006-10-19 |
| AU2005330353B2 (en) | 2010-10-14 |
| NO20072719L (no) | 2007-05-29 |
| CN101052708B (zh) | 2012-08-29 |
| DK1807504T3 (da) | 2011-03-21 |
| PT1807504E (pt) | 2011-03-07 |
| JP4833991B2 (ja) | 2011-12-07 |
| EP1807504B1 (de) | 2011-02-23 |
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