SK286690B6 - Androstdiény, ich použitie, farmaceutická kompozícia s ich obsahom, spôsob ich prípravy a medziprodukty - Google Patents

Androstdiény, ich použitie, farmaceutická kompozícia s ich obsahom, spôsob ich prípravy a medziprodukty Download PDF

Info

Publication number: SK286690B6
Authority: SK; Slovakia
Prior art keywords: group; carbon atoms; methyl; alkyl; formula
Prior art date: 2000-06-28

Application number

SK1813-2002A

Other languages

English (en)

Slovak (sk)

Other versions

SK18132002A3 (sk

Inventor

Bernard Cuenoud

David Beattie

Thomas Hugo Keller

Gaynor Elizabeth Pilgrim

David Andrew Sandham

Simon James Watson

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-28

Filing date

2001-06-26

Publication date

2009-03-05

2001-06-26 Application filed by Novartis Ag filed Critical Novartis Ag

2003-08-05 Publication of SK18132002A3 publication Critical patent/SK18132002A3/sk

2009-03-05 Publication of SK286690B6 publication Critical patent/SK286690B6/sk

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

SK1813-2002A 2000-06-28 2001-06-26 Androstdiény, ich použitie, farmaceutická kompozícia s ich obsahom, spôsob ich prípravy a medziprodukty SK286690B6 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0015876.6A GB0015876D0 (en)	2000-06-28	2000-06-28	Organic compounds
PCT/EP2001/007249 WO2002000679A2 (en)	2000-06-28	2001-06-26	9.alpha.-chloro-6.alpha.-fluoro-17.alpha.-hydroxy-16-methyl-17-beta-methoxycarbonyl-androst-1,4-dienes esterified in position 17.alpha. by a cyclic acyl group

Publications (2)

Publication Number	Publication Date
SK18132002A3 SK18132002A3 (sk)	2003-08-05
SK286690B6 true SK286690B6 (sk)	2009-03-05

Family

ID=9894607

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1813-2002A SK286690B6 (sk)	2000-06-28	2001-06-26	Androstdiény, ich použitie, farmaceutická kompozícia s ich obsahom, spôsob ich prípravy a medziprodukty

Country Status (30)

Country	Link
US (1)	US6921757B2 (cs)
EP (1)	EP1299409B1 (cs)
JP (1)	JP4065399B2 (cs)
KR (1)	KR100483865B1 (cs)
CN (1)	CN1214038C (cs)
AR (1)	AR030707A1 (cs)
AT (1)	ATE292639T1 (cs)
AU (2)	AU2001283891B2 (cs)
BR (1)	BR0112068A (cs)
CA (1)	CA2412541C (cs)
CZ (1)	CZ302513B6 (cs)
DE (1)	DE60109931T2 (cs)
EC (1)	ECSP014101A (cs)
ES (1)	ES2240499T3 (cs)
GB (1)	GB0015876D0 (cs)
HK (1)	HK1055974A1 (cs)
HU (1)	HUP0300783A3 (cs)
IL (2)	IL153703A0 (cs)
MX (1)	MXPA02012830A (cs)
MY (1)	MY129523A (cs)
NO (1)	NO324055B1 (cs)
NZ (1)	NZ523194A (cs)
PE (1)	PE20020179A1 (cs)
PL (1)	PL207722B1 (cs)
PT (1)	PT1299409E (cs)
RU (1)	RU2277100C2 (cs)
SK (1)	SK286690B6 (cs)
TW (1)	TWI232868B (cs)
WO (1)	WO2002000679A2 (cs)
ZA (1)	ZA200300202B (cs)

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Also Published As

Publication number	Publication date
EP1299409A2 (en)	2003-04-09
NZ523194A (en)	2005-08-26
AU8389101A (en)	2002-01-08
AU2001283891B2 (en)	2004-06-17
PL207722B1 (pl)	2011-01-31
GB0015876D0 (en)	2000-08-23
EP1299409B1 (en)	2005-04-06
HK1055974A1 (en)	2004-01-30
TWI232868B (en)	2005-05-21
ZA200300202B (en)	2003-12-31
DE60109931T2 (de)	2006-02-02
NO324055B1 (no)	2007-08-06
HUP0300783A3 (en)	2010-01-28
RU2277100C2 (ru)	2006-05-27
BR0112068A (pt)	2003-04-01
IL153703A (en)	2007-05-15
CN1214038C (zh)	2005-08-10
NO20026253D0 (no)	2002-12-27
NO20026253L (no)	2003-02-18
PL358428A1 (en)	2004-08-09
CZ302513B6 (cs)	2011-06-29
IL153703A0 (en)	2003-07-06
SK18132002A3 (sk)	2003-08-05
JP2004501930A (ja)	2004-01-22
AR030707A1 (es)	2003-09-03
CA2412541C (en)	2009-01-06
HUP0300783A2 (hu)	2003-07-28
JP4065399B2 (ja)	2008-03-26
KR100483865B1 (ko)	2005-04-20
WO2002000679A3 (en)	2002-03-28
US20030158163A1 (en)	2003-08-21
CA2412541A1 (en)	2002-01-03
CN1439018A (zh)	2003-08-27
MXPA02012830A (es)	2003-05-14
PE20020179A1 (es)	2002-04-10
WO2002000679A2 (en)	2002-01-03
MY129523A (en)	2007-04-30
CZ20024203A3 (cs)	2003-04-16
DE60109931D1 (de)	2005-05-12
PT1299409E (pt)	2005-08-31
ATE292639T1 (de)	2005-04-15
US6921757B2 (en)	2005-07-26
ES2240499T3 (es)	2005-10-16
ECSP014101A (es)	2002-01-25
KR20030028768A (ko)	2003-04-10

Publication	Publication Date	Title
SK286690B6 (sk)	2009-03-05	Androstdiény, ich použitie, farmaceutická kompozícia s ich obsahom, spôsob ich prípravy a medziprodukty
AU2001283891A1 (en)	2002-03-28	9.Alpha.-chloro-6.alpha.-fluoro-17.alpha.hydroxy-16-methyl-17-beta-methoxycarbonyl-androst-1,4-dienes esterified in position 17.alpha. by a cyclic acyl group
AT396239B (de)	1993-07-26	Verfahren zur herstellung von neuen in 4-stellung substituierten androstendionderivaten
EP3083603B1 (de)	2017-09-13	Benzimidazolderivate als ep4-liganden
CA2768453A1 (en)	2011-01-27	17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylene phenyl derivatives, methods for the production thereof and use thereof for treating diseases
KR20140069013A (ko)	2014-06-09	에스트라-1,3,5(10),16-테트라엔-3-카복사미드 유도체, 그의 제조방법, 이를 포함하는 약학 제제 및 의약품 제조를 위한 그의 용도
US5885992A (en)	1999-03-23	Triterpene derivative and medicinal composition
SK9792003A3 (en)	2004-01-08	Conjugates of immune cell specific macrolide compounds with anti-inflammatory compounds for improved cellular targeting of anti-inflammatory therapy
HUT73855A (en)	1996-09-30	Delta16 unsaturated c17 heterocyclic steroids useful as steroid c17-20 lyase inhibitors, pharmaceutical compositions containing them and process for their production
RU2348646C1 (ru)	2009-03-10	Полиморфизм додекагидроциклопента[а]фенантренилового эфира тиофенкарбоновой кислоты
DE19961219A1 (de)	2001-07-19	11beta-Phenylestratrien-Derivate mit Fluoralkylgruppen in der aromatischen Seitenkette, deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
DE60000415T2 (de)	2003-05-15	11.beta.-substituierte steroide, verfahren zu ihrer herstellung sowie zwischenprodukte davon, ihre verwendung als medikamente und pharmazeutische zusammensetzungen davon
WO1995021185A1 (en)	1995-08-10	Acyl 3-carboxy aromatic a ring steroid as 5-alpha reductase inhibitors
DE2920726A1 (de)	1980-11-27	Neue kortikoide, ihre herstellung und verwendung

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