RS105704A - Kiseli preparati insulina sa poboljšanom stabilnošću - Google Patents
Kiseli preparati insulina sa poboljšanom stabilnošćuInfo
- Publication number
- RS105704A RS105704A YUP-1057/04A YUP105704A RS105704A RS 105704 A RS105704 A RS 105704A YU P105704 A YUP105704 A YU P105704A RS 105704 A RS105704 A RS 105704A
- Authority
- RS
- Serbia
- Prior art keywords
- combinations
- insulin
- improved stability
- insulin preparations
- acidic
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Ovaj pronalazak se odnosi na farmaceutsku formulaciju koja sadrže neki polipeptid, koji je izabran iz grupe koja obuhvata insulin, neki metabolit insulina, neki analog insulina, neki derivat insulina ili njihove kombinacije; neki tenzid ili kombinacije više tenzida; po izboru neko sredstvo za konzerviranje ili kombinacije više sredstava za konzerviranje; i po izboru neko sredstvo za izotonizaciju, pufer ili druge pomoćne supstance ili njihove kombinacije, pri čemu takva farmaceutska formulacija ima pH-vrednost u kiseloj oblasti.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MEP-287/08A MEP28708A (en) | 2002-06-18 | 2003-06-05 | Acidic insulin preparations with improved stability |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10227232A DE10227232A1 (de) | 2002-06-18 | 2002-06-18 | Saure Insulinzubereitungen mit verbesserter Stabilität |
PCT/EP2003/005887 WO2003105888A1 (de) | 2002-06-18 | 2003-06-05 | Saure insulinzubereitungen mit verbesserter stabilität |
Publications (2)
Publication Number | Publication Date |
---|---|
RS105704A true RS105704A (sr) | 2007-02-05 |
RS52388B RS52388B (sr) | 2013-02-28 |
Family
ID=29723248
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU105704A RS52388B (sr) | 2002-06-18 | 2003-06-05 | Kiseli preparati insulina sa poboljšanom stabilnošću |
Country Status (38)
Country | Link |
---|---|
US (4) | US20040048783A1 (sr) |
EP (2) | EP2305288B1 (sr) |
JP (2) | JP5237522B2 (sr) |
KR (1) | KR101040029B1 (sr) |
CN (2) | CN1662252A (sr) |
AR (1) | AR039688A1 (sr) |
AU (1) | AU2003238471B2 (sr) |
BR (1) | BRPI0311877B8 (sr) |
CA (1) | CA2490116C (sr) |
CR (1) | CR7614A (sr) |
CY (1) | CY1113537T1 (sr) |
DE (1) | DE10227232A1 (sr) |
DK (1) | DK1517697T3 (sr) |
EC (1) | ECSP045496A (sr) |
ES (2) | ES2397158T3 (sr) |
HN (1) | HN2003000184A (sr) |
HR (1) | HRP20041200B1 (sr) |
IL (1) | IL165788A (sr) |
MA (1) | MA27205A1 (sr) |
ME (1) | MEP28708A (sr) |
MX (1) | MXPA04012233A (sr) |
MY (1) | MY142354A (sr) |
NO (1) | NO328567B1 (sr) |
NZ (1) | NZ537211A (sr) |
OA (1) | OA12870A (sr) |
PA (1) | PA8575701A1 (sr) |
PE (1) | PE20040560A1 (sr) |
PL (1) | PL208773B1 (sr) |
PT (2) | PT1517697E (sr) |
RS (1) | RS52388B (sr) |
RU (1) | RU2313362C2 (sr) |
SV (1) | SV2004001556A (sr) |
TN (1) | TNSN04249A1 (sr) |
TW (1) | TWI315201B (sr) |
UA (1) | UA79477C2 (sr) |
UY (1) | UY27854A1 (sr) |
WO (1) | WO2003105888A1 (sr) |
ZA (1) | ZA200409273B (sr) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
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DE10227232A1 (de) * | 2002-06-18 | 2004-01-15 | Aventis Pharma Deutschland Gmbh | Saure Insulinzubereitungen mit verbesserter Stabilität |
EP2106790B1 (en) * | 2004-03-12 | 2012-10-24 | Biodel, Inc. | Rapid acting drug delivery compositions |
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UA75030C2 (en) * | 2005-11-30 | 2006-03-15 | Viktor Oleksandrovych Bykov | Method for obtaining stable aqueous solutions of drugs |
WO2007135117A2 (en) * | 2006-05-24 | 2007-11-29 | Novo Nordisk A/S | Soluble, stable insulin-containing formulations |
DE102006031955A1 (de) | 2006-07-11 | 2008-01-17 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende |
DE102006031962A1 (de) | 2006-07-11 | 2008-01-17 | Sanofi-Aventis Deutschland Gmbh | Amidiertes Insulin Glargin |
WO2008132229A2 (en) * | 2007-04-30 | 2008-11-06 | Novo Nordisk A/S | Highly concentrated insulin solutions and compositions |
EP2234644B1 (en) * | 2008-01-04 | 2013-07-31 | Biodel, Inc. | Insulin formulations for insulin release as a function of tissue glucose levels |
CA2711749A1 (en) | 2008-01-09 | 2009-07-16 | Sanofi-Aventis Deutschland Gmbh | Novel insulin derivatives having an extremely delayed time-action profile |
NZ586589A (en) | 2008-01-09 | 2012-04-27 | Sanofi Aventis Deutschland | Novel insulin analogues having an extremely delayed time-action profile |
RU2014150367A (ru) * | 2008-08-29 | 2015-06-27 | Джензим Корпорейшн | Лекарственные средства с контролируемым высвобождением, содержащие пептиды |
WO2010028055A1 (en) * | 2008-09-02 | 2010-03-11 | Biodel, Inc. | Insulin with a basal release profile |
KR101820024B1 (ko) | 2008-10-17 | 2018-01-18 | 사노피-아벤티스 도이칠란트 게엠베하 | 인슐린과 glp-1 효능제의 병용물 |
US9060927B2 (en) * | 2009-03-03 | 2015-06-23 | Biodel Inc. | Insulin formulations for rapid uptake |
ES2614161T3 (es) * | 2009-07-06 | 2017-05-29 | Sanofi-Aventis Deutschland Gmbh | Preparados acuosos de insulina que comprenden metionina |
TR201809460T4 (tr) | 2009-11-13 | 2018-07-23 | Sanofi Aventis Deutschland | Bir GLP- 1-agonisti, bir insülin ve metiyonin içeren farmasötik bileşim. |
ES2667069T3 (es) | 2009-11-13 | 2018-05-09 | Sanofi-Aventis Deutschland Gmbh | Composición farmacéutica que comprende desPro36exendina-4(1-39)-Lys6-NH2 y metionina |
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US8637458B2 (en) | 2010-05-12 | 2014-01-28 | Biodel Inc. | Insulin with a stable basal release profile |
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US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
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-
2002
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2003
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- 2003-06-05 WO PCT/EP2003/005887 patent/WO2003105888A1/de active Application Filing
- 2003-06-05 EP EP10178842.0A patent/EP2305288B1/de not_active Expired - Lifetime
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