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DK257988D0 - Nye peptider - Google Patents

Nye peptider

Info

Publication number
DK257988D0
DK257988D0 DK257988A DK257988A DK257988D0 DK 257988 D0 DK257988 D0 DK 257988D0 DK 257988 A DK257988 A DK 257988A DK 257988 A DK257988 A DK 257988A DK 257988 D0 DK257988 D0 DK 257988D0
Authority
DK
Denmark
Prior art keywords
new peptides
peptides
new
Prior art date
Application number
DK257988A
Other languages
English (en)
Inventor
Jens Joergen Veilgaard Brange
Svend Havelund
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri As filed Critical Novo Industri As
Priority to DK257988A priority Critical patent/DK257988D0/da
Publication of DK257988D0 publication Critical patent/DK257988D0/da
Priority to KR1019900700042A priority patent/KR900701840A/ko
Priority to EP89906057A priority patent/EP0419504B1/en
Priority to PCT/DK1989/000117 priority patent/WO1989010937A1/en
Priority to HU893263A priority patent/HUT55442A/hu
Priority to DE89906057T priority patent/DE68912777T2/de
Priority to AT89906057T priority patent/ATE100824T1/de
Priority to AU36928/89A priority patent/AU615760B2/en
Priority to ZA893508A priority patent/ZA893508B/xx
Priority to IE153689A priority patent/IE65504B1/en
Priority to NZ229108A priority patent/NZ229108A/en
Priority to DK265590A priority patent/DK265590A/da
Priority to NO90904841A priority patent/NO904841L/no
Priority to FI905566A priority patent/FI905566A0/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK257988A 1988-05-11 1988-05-11 Nye peptider DK257988D0 (da)

Priority Applications (14)

Application Number Priority Date Filing Date Title
DK257988A DK257988D0 (da) 1988-05-11 1988-05-11 Nye peptider
AU36928/89A AU615760B2 (en) 1988-05-11 1989-05-10 Insulin analogues
AT89906057T ATE100824T1 (de) 1988-05-11 1989-05-10 Insulin-analoge.
EP89906057A EP0419504B1 (en) 1988-05-11 1989-05-10 Insulin analogues
PCT/DK1989/000117 WO1989010937A1 (en) 1988-05-11 1989-05-10 Insulin analogues
HU893263A HUT55442A (en) 1988-05-11 1989-05-10 Process for producing insuline analogues
DE89906057T DE68912777T2 (de) 1988-05-11 1989-05-10 Insulin-analoge.
KR1019900700042A KR900701840A (ko) 1988-05-11 1989-05-10 인슐린 유사체
ZA893508A ZA893508B (en) 1988-05-11 1989-05-11 Insulin analogues
IE153689A IE65504B1 (en) 1988-05-11 1989-05-11 Insulin analogues
NZ229108A NZ229108A (en) 1988-05-11 1989-05-12 Insulin analogues and pharmaceutical compositions
DK265590A DK265590A (da) 1988-05-11 1990-11-06 Insulinanaloger
NO90904841A NO904841L (no) 1988-05-11 1990-11-07 Insulinanaloger.
FI905566A FI905566A0 (fi) 1988-05-11 1990-11-09 Insulin analoger.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK257988A DK257988D0 (da) 1988-05-11 1988-05-11 Nye peptider

Publications (1)

Publication Number Publication Date
DK257988D0 true DK257988D0 (da) 1988-05-11

Family

ID=8113334

Family Applications (1)

Application Number Title Priority Date Filing Date
DK257988A DK257988D0 (da) 1988-05-11 1988-05-11 Nye peptider

Country Status (10)

Country Link
EP (1) EP0419504B1 (da)
KR (1) KR900701840A (da)
AU (1) AU615760B2 (da)
DE (1) DE68912777T2 (da)
DK (1) DK257988D0 (da)
HU (1) HUT55442A (da)
IE (1) IE65504B1 (da)
NZ (1) NZ229108A (da)
WO (1) WO1989010937A1 (da)
ZA (1) ZA893508B (da)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716927A (en) * 1988-12-23 1998-02-10 Novo Nordisk A/S Insulin analogs having a modified B-chain
HUT56857A (en) * 1988-12-23 1991-10-28 Novo Nordisk As Human insulin analogues
DK155690D0 (da) * 1990-06-28 1990-06-28 Novo Nordisk As Nye peptider
DK10191D0 (da) * 1991-01-22 1991-01-22 Novo Nordisk As Hidtil ukendte peptider
DE19726167B4 (de) 1997-06-20 2008-01-24 Sanofi-Aventis Deutschland Gmbh Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung
DE19825447A1 (de) * 1998-06-06 1999-12-09 Hoechst Marion Roussel De Gmbh Neue Insulinanaloga mit erhöhter Zinkbildung
DK1265630T3 (da) 2000-03-24 2006-10-09 Genentech Inc Anvendelse af insulin til behandling af brusksygdomme
US7060675B2 (en) * 2001-02-15 2006-06-13 Nobex Corporation Methods of treating diabetes mellitus
US7202059B2 (en) 2001-02-20 2007-04-10 Sanofi-Aventis Deutschland Gmbh Fusion proteins capable of being secreted into a fermentation medium
US7638618B2 (en) 2001-02-20 2009-12-29 Sanofi-Aventis Deutschland Gmbh Nucleic acids encoding a hirudin and pro-insulin as superscretable peptides and for parallel improvement of the exported forms of one or more polypeptides of interest
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
DE10227232A1 (de) 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
US7193035B2 (en) 2002-10-29 2007-03-20 Sanofi-Aventis Deutschland Gmbh Crystals of insulin analogs and processes for their preparation
US7981635B2 (en) 2005-09-14 2011-07-19 Sanofi-Aventis Deutschland Gmbh Cleavage of precursors of insulins by a variant of trypsin
ES2601839T3 (es) 2006-09-22 2017-02-16 Novo Nordisk A/S Análogos de insulina resistentes a proteasas
EP2229406B1 (de) 2008-01-09 2015-04-22 Sanofi-Aventis Deutschland GmbH Neue insulinderivate mit extrem verzögertem zeit- / wirkungsprofil
ES2613152T3 (es) 2008-01-09 2017-05-22 Sanofi-Aventis Deutschland Gmbh Nuevos derivados de insulina con perfil tiempo/acción extremadamente retardado
WO2009112583A2 (en) 2008-03-14 2009-09-17 Novo Nordisk A/S Protease-stabilized insulin analogues
ES2609288T3 (es) 2008-03-18 2017-04-19 Novo Nordisk A/S Análogos de insulina acilada, estabilizados frente a proteasas
DE102008053048A1 (de) 2008-10-24 2010-04-29 Sanofi-Aventis Deutschland Gmbh Kombination von einem Insulin und einem GLP-1-Agonisten
DE102009038210A1 (de) 2009-08-20 2011-03-03 Sanofi-Aventis Deutschland Gmbh Kombination von einem Insulin und einem GLP-1-Agonisten
DE102008051834A1 (de) 2008-10-17 2010-04-22 Sanofi-Aventis Deutschland Gmbh Kombination von einem Insulin und einem GLP-1-Agonisten
KR101820024B1 (ko) 2008-10-17 2018-01-18 사노피-아벤티스 도이칠란트 게엠베하 인슐린과 glp-1 효능제의 병용물
US20120241356A1 (en) * 2009-07-06 2012-09-27 Sanofi-Aventis Deutschland Gmbh Heat- and vibration-stable insulin preparations
EP2451471A1 (de) * 2009-07-06 2012-05-16 Sanofi-Aventis Deutschland GmbH Langsamwirkende insulinzubereitungen
PT2451437T (pt) 2009-07-06 2017-01-17 Sanofi Aventis Deutschland Preparações aquosas de insulina contendo metionina
KR101759499B1 (ko) 2009-07-31 2017-07-19 사노피-아벤티스 도이칠란트 게엠베하 지속형 인슐린 조성물
MA33467B1 (fr) 2009-07-31 2012-07-03 Sanofi Aventis Deutschland Promédicaments comprenant un conjugué insuline-lieur
PL3417871T3 (pl) 2009-11-13 2021-06-14 Sanofi-Aventis Deutschland Gmbh Kompozycja farmaceutyczna zawierająca agonistę GLP-1, insulinę i metioninę
LT2498801T (lt) 2009-11-13 2018-05-10 Sanofi-Aventis Deutschland Gmbh Farmacinė kompozicija, apimanti despro36eksendin-4(1-39)-lys6-nh2 ir metioniną
MX339614B (es) 2010-08-30 2016-06-02 Sanofi - Aventis Deutschland GmbH Uso de ave0010 para la fabricacion de un medicamento para el tratamiento de la diabetes mellitus tipo 2.
EP2438930A1 (en) 2010-09-17 2012-04-11 Sanofi-Aventis Deutschland GmbH Prodrugs comprising an exendin linker conjugate
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
PL2750699T3 (pl) 2011-08-29 2015-12-31 Sanofi Aventis Deutschland Kombinacja farmaceutyczna do stosowania w kontroli glikemii u pacjentów z cukrzycą typu 2
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
MX2014006698A (es) 2011-12-15 2014-07-09 Shanghai Hengrui Pharm Co Ltd Analogo de insulina humana y derivado acilado del mismo.
US20130315891A1 (en) 2012-05-25 2013-11-28 Matthew Charles Formulations of human tissue kallikrein-1 for parenteral delivery and related methods
ES2625548T3 (es) 2012-06-04 2017-07-19 DiaMedica Therapeutics Inc. Isoformas de glicosilación de la calicreína-1 tisular humana
RU2015129087A (ru) 2012-12-19 2017-02-02 Вокхардт Лимитед Стабильная водная композиция, содержащая инсулин человека или его аналог или производное
TWI641381B (zh) 2013-02-04 2018-11-21 法商賽諾菲公司 胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物
AU2014326181A1 (en) 2013-09-30 2016-03-17 Wockhardt Limited Pharmaceutical composition
BR112016007166A2 (pt) 2013-10-07 2017-09-12 Novo Nordisk As derivado de um análogo de insulina
CN105960249B (zh) 2014-01-09 2021-03-16 赛诺菲 胰岛素类似物和/或胰岛素衍生物的稳定化药物制剂
BR112016013832A2 (pt) 2014-01-09 2017-08-08 Sanofi Sa Uso de análogo e/ou derivado de insulina, formulação farmacêutica e processo para a preparação da mesma, kit e dispositivo médico
CA2932873A1 (en) 2014-01-09 2015-07-16 Sanofi Stabilized pharmaceutical formulations of insulin aspart
WO2016001862A1 (en) 2014-07-04 2016-01-07 Wockhardt Limited Extended release formulations of insulins
CA2970200A1 (en) 2014-12-12 2016-06-16 Sanofi-Aventis Deutschland Gmbh Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患之治療
EP3260548A1 (en) 2016-06-21 2017-12-27 Enzypep B.V. Enzymatic coupling of (oligo)peptides to the b-chain of an insulin receptor ligand
CN110087674B (zh) 2016-12-16 2023-01-03 诺和诺德股份有限公司 含胰岛素的药物组合物
WO2018165551A1 (en) 2017-03-09 2018-09-13 Diamedica Inc. Dosage forms of tissue kallikrein 1

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2536040A1 (de) * 1975-08-13 1977-02-24 Hoechst Ag Insulin-analoga mit biologischer wirkung
NZ187300A (en) * 1977-05-27 1982-08-17 Univ California Dna transfer vector and micro-organism modified to contain a nucleotide sequence equivalent to the gene of a higher organism
IE50892B1 (en) * 1980-02-11 1986-08-06 Novo Industri As Process for preparing insulin esters
CA1339416C (en) * 1987-02-25 1997-09-02 Liselotte Langkjaer Insulin derivatives

Also Published As

Publication number Publication date
WO1989010937A1 (en) 1989-11-16
HU893263D0 (en) 1991-03-28
DE68912777T2 (de) 1994-05-11
IE65504B1 (en) 1995-11-01
KR900701840A (ko) 1990-12-04
HUT55442A (en) 1991-05-28
ZA893508B (en) 1990-01-31
IE891536L (en) 1989-11-11
NZ229108A (en) 1992-05-26
AU615760B2 (en) 1991-10-10
DE68912777D1 (de) 1994-03-10
AU3692889A (en) 1989-11-29
EP0419504B1 (en) 1994-01-26
EP0419504A1 (en) 1991-04-03

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Legal Events

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AHS Application shelved for other reasons than non-payment