NO20050481L - Doseringsform av pramipexol for dosering en gang pr. dag - Google Patents
Doseringsform av pramipexol for dosering en gang pr. dagInfo
- Publication number
- NO20050481L NO20050481L NO20050481A NO20050481A NO20050481L NO 20050481 L NO20050481 L NO 20050481L NO 20050481 A NO20050481 A NO 20050481A NO 20050481 A NO20050481 A NO 20050481A NO 20050481 L NO20050481 L NO 20050481L
- Authority
- NO
- Norway
- Prior art keywords
- pramipexole
- absorption
- day
- once
- hours
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Et oralt avleverbart, farmasøytisk preparat omfatter en terapeutisk effektiv mengde av pramipexol eller et farmasøytisk akseptabelt salt derav og minst en farmasøytisk akseptabel eksipient.Preparatet omfatter minst en av: (a) en in vitro frigivningsprofil der ikke mer enn rundt 20% av pramipexolen er oppløst innen 2 timer etter anbringelse av preparatet i en standard oppløsning; og (b) en in vivo pramipexol absorpsjonsprofil etter en enkelt dose oraladministrering til friske, voksne personer der tiden for å nå gjennomsnittlig 20% absorpsjon er større enn rundt 2 timer og/eller tiden for å nå gjennomsnittlig 40% absorpsjon er større enn rundt 4 timer. Preparatet er nyttig for oral administrering, ikke mindre enn en gang daglig, til et individ med en tilstand eller lidelse for hvilken en dopaminreseptoragonist er indikert.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39842702P | 2002-07-25 | 2002-07-25 | |
US39844702P | 2002-07-25 | 2002-07-25 | |
US47951403P | 2003-06-18 | 2003-06-18 | |
PCT/US2003/023522 WO2004010999A1 (en) | 2002-07-25 | 2003-07-25 | Pramipexole once-daily dosage form |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20050481L true NO20050481L (no) | 2005-01-27 |
Family
ID=31192088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20050481A NO20050481L (no) | 2002-07-25 | 2005-01-27 | Doseringsform av pramipexol for dosering en gang pr. dag |
Country Status (40)
Country | Link |
---|---|
US (2) | US8679533B2 (no) |
EP (2) | EP2289514B9 (no) |
JP (1) | JP4607584B2 (no) |
KR (2) | KR101066374B1 (no) |
CN (1) | CN1671381B (no) |
AP (1) | AP2223A (no) |
AR (1) | AR040682A1 (no) |
AU (1) | AU2003256921B2 (no) |
BR (1) | BR0312948A (no) |
CA (1) | CA2493629C (no) |
CU (1) | CU23468B7 (no) |
CY (2) | CY1114263T1 (no) |
DE (1) | DE20321906U1 (no) |
DK (2) | DK1536792T3 (no) |
EA (1) | EA017595B1 (no) |
EC (1) | ECSP055569A (no) |
ES (2) | ES2421787T3 (no) |
GE (1) | GEP20074047B (no) |
HK (1) | HK1078007A1 (no) |
HR (1) | HRP20041234B1 (no) |
IL (1) | IL166076A0 (no) |
IS (1) | IS7613A (no) |
MA (1) | MA27372A1 (no) |
ME (1) | ME00347B (no) |
MX (1) | MXPA05000980A (no) |
MY (1) | MY142204A (no) |
NO (1) | NO20050481L (no) |
NZ (1) | NZ562681A (no) |
OA (1) | OA12889A (no) |
PA (1) | PA8578501A1 (no) |
PE (1) | PE20040134A1 (no) |
PL (1) | PL375444A1 (no) |
PT (2) | PT1536792E (no) |
RS (1) | RS52764B (no) |
SG (1) | SG177011A1 (no) |
SI (2) | SI2289514T1 (no) |
TW (1) | TWI351955B (no) |
UY (1) | UY27913A1 (no) |
WO (1) | WO2004010999A1 (no) |
ZA (1) | ZA200500015B (no) |
Families Citing this family (44)
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US20050226926A1 (en) | 2002-07-25 | 2005-10-13 | Pfizer Inc | Sustained-release tablet composition of pramipexole |
US7365086B2 (en) * | 2003-07-25 | 2008-04-29 | Synthon Ip Inc. | Pramipexole acid addition salts |
PT1781260E (pt) * | 2004-08-13 | 2010-12-20 | Boehringer Ingelheim Int | Formulação em comprimido de libertação prolongada contendo pramipexole ou um seu sal farmaceuticamente aceitável, um método para a preparação do mesmo e sua utilização |
EA200700388A1 (ru) * | 2004-08-13 | 2007-08-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Композиция пеллеты пролонгированного высвобождения, содержащая прамипексол или его фармацевтически приемлемую соль, способ её изготовления и её применение |
KR20070058540A (ko) * | 2004-10-01 | 2007-06-08 | 니폰 조키 세야쿠 가부시키가이샤 | 고형 의약제제 |
WO2006046256A1 (en) * | 2004-10-27 | 2006-05-04 | Alembic Limited | Extended release formulation of pramipexole dihydrochloride |
WO2007090882A2 (en) * | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical extended release compositions comprising pramipexole |
US20090041844A1 (en) * | 2006-02-10 | 2009-02-12 | Boehringer Ingelheim International Gmbh | Modified Release Formulation |
WO2007090883A1 (en) * | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Extended release formulation |
US8518926B2 (en) * | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
CA2652251A1 (en) * | 2006-05-16 | 2007-11-29 | Knopp Neurosciences, Inc. | Compositions of r(+) and s(-) pramipexole and methods for using the same |
US20080254118A1 (en) * | 2007-04-11 | 2008-10-16 | Hans-Werner Wernersbach | Process for preparing pramipexole dihydrochloride tablets |
US8524695B2 (en) * | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
EP2129382A4 (en) | 2007-02-21 | 2011-01-19 | Univ Michigan | COMPOSITIONS AND METHODS FOR HEART MUSCLE PREVENTION |
US8519148B2 (en) | 2007-03-14 | 2013-08-27 | Knopp Neurosciences, Inc. | Synthesis of chirally purified substituted benzothiazole diamines |
EP2167080A1 (en) * | 2007-05-25 | 2010-03-31 | Boehringer Ingelheim International GmbH | Pharmaceutical formulation comprising pramipexole |
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EP2291178A4 (en) * | 2008-06-09 | 2013-07-24 | Supernus Pharmaceuticals Inc | PRAMIPEXOL FORMULATIONS WITH CONTROLLED RELEASE |
EP2334185A4 (en) | 2008-08-19 | 2011-09-21 | Knopp Neurosciences Inc | COMPOSITIONS AND METHODS FOR USE OF (R) -PRAMIPEXOL |
AU2010234244A1 (en) * | 2009-04-09 | 2011-10-13 | Purdue Pharma | Once-daily oral IR/CR pramipexole formulation |
MX2012000096A (es) * | 2009-07-02 | 2012-04-02 | Supernus Pharmaceuticals Inc | Un metodo de tratamiento de un trastorno neurologico. |
WO2011037976A2 (en) * | 2009-09-22 | 2011-03-31 | Dr. Reddy's Laboratories Limited | Pramipexole pharmaceutical formulations |
WO2011086182A2 (en) * | 2010-01-18 | 2011-07-21 | Synthon Bv | Pramipexole extended release tablets |
TR201001862A1 (tr) * | 2010-03-11 | 2011-10-21 | Sanovel �La� San.Ve T�C.A.�. | Kontrollü salım gerçekleştiren pramipeksol formülasyonları. |
US20130209553A1 (en) | 2010-04-15 | 2013-08-15 | Cadila Healthcare Limited | Extended release pharmaceutical compositions of pramipexole |
WO2011148243A1 (en) | 2010-05-24 | 2011-12-01 | Lupin Limited | Extended release formulation of pramipexole |
CN102670550A (zh) * | 2011-03-14 | 2012-09-19 | 北京天衡药物研究院 | 盐酸普拉克索渗透泵型控释片 |
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CN102406626B (zh) * | 2011-12-02 | 2013-08-28 | 深圳海王药业有限公司 | 盐酸普拉克索缓释片剂及其制备方法 |
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EP2732812A1 (de) | 2012-11-15 | 2014-05-21 | Aristo Pharma GmbH | Pramipexol-Retardtablettenformulierung |
CN103058953B (zh) * | 2012-11-22 | 2015-03-25 | 刘炜 | 用于治疗神经疾病的四氢苯并噻唑衍生物 |
US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
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HUE054185T2 (hu) | 2013-07-12 | 2021-08-30 | Knopp Biosciences Llc | Eozinofilek és/vagy bazofilek megemelkedett szintjének kezelése |
US9763918B2 (en) | 2013-08-13 | 2017-09-19 | Knopp Biosciences Llc | Compositions and methods for treating chronic urticaria |
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CN104606162B (zh) * | 2015-01-07 | 2017-03-29 | 海南康虹医药科技开发有限公司 | 一种盐酸普拉克索缓释制剂及其制备方法 |
CN104784155B (zh) * | 2015-05-15 | 2018-02-23 | 中国药科大学 | 一种盐酸普拉克索组合微丸胶囊及其制备方法 |
CN105030721B (zh) * | 2015-08-30 | 2018-05-04 | 南京康川济医药科技有限公司 | 一种含有盐酸普拉克索的口服固体组合物 |
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CN110402304A (zh) * | 2016-12-21 | 2019-11-01 | 哈索赫伯特施密特有限两合公司 | 用于酸洗合成材料的酸洗液 |
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