ZA9811162B
(en)
|
1997-12-12 |
2000-06-07 |
Genentech Inc |
Treatment with anti-ERBB2 antibodies.
|
KR100960211B1
(ko)
|
1998-05-06 |
2010-05-27 |
제넨테크, 인크. |
이온 교환 크로마토그래피에 의한 단백질 정제 방법
|
DK1084136T3
(da)
|
1998-06-01 |
2005-01-03 |
Genentech Inc |
Adskillelse af monomere af et antistof fra dets multimere ved anvendelse af ionbytterchromatografi
|
US20030086924A1
(en)
*
|
1999-06-25 |
2003-05-08 |
Genentech, Inc. |
Treatment with anti-ErbB2 antibodies
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
US20040013667A1
(en)
*
|
1999-06-25 |
2004-01-22 |
Genentech, Inc. |
Treatment with anti-ErbB2 antibodies
|
EP1280923A2
(en)
*
|
2000-04-28 |
2003-02-05 |
Millennium Pharmaceuticals, Inc. |
14094, a human trypsin family member and uses thereof
|
US6790709B2
(en)
*
|
2001-11-30 |
2004-09-14 |
Intel Corporation |
Backside metallization on microelectronic dice having beveled sides for effective thermal contact with heat dissipation devices
|
WO2003062375A2
(en)
|
2001-12-19 |
2003-07-31 |
Genentech, Inc. |
Stabilizing polypeptides which have been exposed to urea
|
FR2840695B1
(fr)
*
|
2002-06-07 |
2004-10-08 |
Chevrillon Philippe Ind |
Procede de fabrication de ceintures d'impression
|
US7998705B2
(en)
*
|
2002-08-06 |
2011-08-16 |
FUJIFILM Diosynth Biotechnologies U.S.A., Inc |
Increased dynamic binding capacity in ion exchange chromatography by addition of polyethylene glycol
|
DK1543038T4
(da)
|
2002-09-11 |
2020-11-09 |
Genentech Inc |
Proteinoprensning
|
ES2523837T3
(es)
*
|
2003-07-18 |
2014-12-01 |
Amgen Inc. |
Agentes de unión específica al factor de crecimiento de hepatocitos
|
US8265759B2
(en)
|
2003-10-15 |
2012-09-11 |
Rmx, Llc |
Device and method for treating disorders of the cardiovascular system or heart
|
US8467876B2
(en)
|
2003-10-15 |
2013-06-18 |
Rmx, Llc |
Breathing disorder detection and therapy delivery device and method
|
US9259573B2
(en)
|
2003-10-15 |
2016-02-16 |
Rmx, Llc |
Device and method for manipulating exhalation
|
US8140164B2
(en)
|
2003-10-15 |
2012-03-20 |
Rmx, Llc |
Therapeutic diaphragm stimulation device and method
|
US7979128B2
(en)
|
2003-10-15 |
2011-07-12 |
Rmx, Llc |
Device and method for gradually controlling breathing
|
US8160711B2
(en)
|
2003-10-15 |
2012-04-17 |
Rmx, Llc |
Multimode device and method for controlling breathing
|
US7970475B2
(en)
|
2003-10-15 |
2011-06-28 |
Rmx, Llc |
Device and method for biasing lung volume
|
US8244358B2
(en)
|
2003-10-15 |
2012-08-14 |
Rmx, Llc |
Device and method for treating obstructive sleep apnea
|
ES2550311T3
(es)
|
2003-11-05 |
2015-11-06 |
Roche Glycart Ag |
Moléculas de unión a antígeno con afinidad de unión a receptores Fc y función efectora incrementadas
|
EP1720536B1
(en)
|
2004-02-06 |
2012-04-25 |
PHARMATEL (R&D) PTY LIMITED as Trustee for the PHARMATEL (R & D) TRUST |
Use of aminosalicylates in diarrhoea-predominent irritable bowel syndrome
|
US20060234907A1
(en)
*
|
2004-02-13 |
2006-10-19 |
Werner Gehringer |
Albumin solution and process for the production thereof
|
US7713629B2
(en)
|
2004-03-26 |
2010-05-11 |
Florida State University Research Foundation |
Hydrophobic fluorinated polyelectrolyte complex films and associated methods
|
US9056125B2
(en)
|
2004-05-17 |
2015-06-16 |
Florida State University Research Foundation, Inc. |
Films for controlled cell growth and adhesion
|
SV2006002143A
(es)
*
|
2004-06-16 |
2006-01-26 |
Genentech Inc |
Uso de un anticuerpo para el tratamiento del cancer resistente al platino
|
KR20170054551A
(ko)
|
2004-07-22 |
2017-05-17 |
제넨테크, 인크. |
Her2 항체 조성물
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
JP2008523073A
(ja)
*
|
2004-12-07 |
2008-07-03 |
ジェネンテック・インコーポレーテッド |
Her阻害剤を用いた治療のための患者の選択
|
KR20150083139A
(ko)
|
2005-01-21 |
2015-07-16 |
제넨테크, 인크. |
Her 항체의 고정 용량 투여법
|
ZA200706247B
(en)
*
|
2005-02-09 |
2008-11-26 |
Genentech Inc |
Inhibiting HER2 shedding with matrix metalloprotease antagonists
|
DK1850874T3
(da)
|
2005-02-23 |
2013-11-11 |
Genentech Inc |
Forlængelse af tid til sygdomsprogression eller overlevelse for ovariecancer ved anvendelse af pertuzumab
|
US7585955B2
(en)
*
|
2005-03-03 |
2009-09-08 |
Florida State University Research Foundation, Inc |
Protein separation from a protein mixture
|
WO2006096861A2
(en)
*
|
2005-03-08 |
2006-09-14 |
Genentech, Inc. |
METHODS FOR IDENTIFYING TUMORS RESPONSIVE TO TREATMENT WITH HER DIMERIZATION INHIBITORS (HDIs)
|
US7459542B2
(en)
*
|
2005-03-10 |
2008-12-02 |
Florida State University Research Foundation, Inc. |
Separation of albumin from protein samples
|
JP2006316040A
(ja)
|
2005-05-13 |
2006-11-24 |
Genentech Inc |
Herceptin(登録商標)補助療法
|
TWI391399B
(zh)
†
|
2005-05-25 |
2013-04-01 |
Hoffmann La Roche |
測定溶離多肽之鹽濃度之方法
|
PE20070207A1
(es)
|
2005-07-22 |
2007-03-09 |
Genentech Inc |
Tratamiento combinado de los tumores que expresan el her
|
US7452872B2
(en)
|
2005-08-24 |
2008-11-18 |
Salix Pharmaceuticals, Inc. |
Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
|
US8921344B2
(en)
|
2006-11-03 |
2014-12-30 |
Salix Pharmaceuticals, Inc. |
Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
|
AU2007235484B2
(en)
|
2006-04-05 |
2013-11-07 |
Abbvie Biotechnology Ltd |
Antibody purification
|
EP2059589A2
(en)
*
|
2006-08-01 |
2009-05-20 |
Illumigen Biosciences Inc. |
Pharmaceutical manufacturing methods
|
FI2061803T4
(fi)
*
|
2006-08-28 |
2023-03-14 |
|
Process for the purification of fc-containing proteins
|
WO2008025747A1
(en)
*
|
2006-08-28 |
2008-03-06 |
Ares Trading S.A. |
Process for the purification of fc-fusion proteins
|
US8911964B2
(en)
|
2006-09-13 |
2014-12-16 |
Abbvie Inc. |
Fed-batch method of making human anti-TNF-alpha antibody
|
CN103555651A
(zh)
|
2006-09-13 |
2014-02-05 |
Abbvie公司 |
细胞培养改良
|
US8280513B2
(en)
|
2006-12-22 |
2012-10-02 |
Rmx, Llc |
Device and method to treat flow limitations
|
CN101646431B
(zh)
*
|
2007-01-22 |
2012-06-27 |
健泰科生物技术公司 |
蛋白质的聚电解质沉淀和纯化
|
PL2132573T3
(pl)
|
2007-03-02 |
2014-09-30 |
Genentech Inc |
Prognozowanie odpowiedzi na inhibitor dimeryzacji HER oparte na niskiej ekspresji HER3
|
US7960139B2
(en)
|
2007-03-23 |
2011-06-14 |
Academia Sinica |
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
|
BRPI0812288A2
(pt)
*
|
2007-06-01 |
2014-11-25 |
Hoffmann La Roche |
Purificação de imunoglobulina.
|
EP2592156B1
(en)
*
|
2007-06-08 |
2016-04-20 |
Genentech, Inc. |
Gene expression markers of tumor resistance to HER2 inhibitor treatment
|
US9551033B2
(en)
|
2007-06-08 |
2017-01-24 |
Genentech, Inc. |
Gene expression markers of tumor resistance to HER2 inhibitor treatment
|
EP2215117B2
(en)
|
2007-10-30 |
2018-01-10 |
Genentech, Inc. |
Antibody purification by cation exchange chromatography
|
AU2012227163B2
(en)
*
|
2007-10-30 |
2015-07-16 |
Genentech, Inc. |
Antibody purification by cation exchange chromatography
|
US8557243B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
EFGR antibodies comprising modular recognition domains
|
US8454960B2
(en)
|
2008-01-03 |
2013-06-04 |
The Scripps Research Institute |
Multispecific antibody targeting and multivalency through modular recognition domains
|
US8574577B2
(en)
|
2008-01-03 |
2013-11-05 |
The Scripps Research Institute |
VEGF antibodies comprising modular recognition domains
|
US8557242B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
ERBB2 antibodies comprising modular recognition domains
|
KR101658247B1
(ko)
|
2008-01-03 |
2016-09-22 |
더 스크립스 리서치 인스티튜트 |
모듈 인식 도메인을 통한 항체 표적화
|
TWI472339B
(zh)
*
|
2008-01-30 |
2015-02-11 |
Genentech Inc |
包含結合至her2結構域ii之抗體及其酸性變異體的組合物
|
EP3269366B1
(en)
|
2008-03-18 |
2020-01-15 |
Genentech, Inc. |
Combinations of an anti-her2 antibody-drug conjugate and lapatinib, and methods of use
|
SG190572A1
(en)
|
2008-04-29 |
2013-06-28 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
JP2011523853A
(ja)
|
2008-06-03 |
2011-08-25 |
アボット・ラボラトリーズ |
二重可変ドメイン免疫グロブリン及びその使用
|
BRPI0913366A8
(pt)
|
2008-06-03 |
2017-07-11 |
Abbott Lab |
Imunoglobulinas de domínio variável duplo e seus usos
|
BRPI0812682A2
(pt)
*
|
2008-06-16 |
2010-06-22 |
Genentech Inc |
tratamento de cáncer de mama metastático
|
ES2442024T3
(es)
|
2008-07-15 |
2014-02-07 |
Academia Sinica |
Matrices de glucano sobre portaobjetos de vidrio revestidos con aluminio de tipo PTFE y métodos relacionados
|
PT2848625T
(pt)
*
|
2008-08-14 |
2019-10-25 |
Genentech Inc |
Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena.
|
TW201014605A
(en)
|
2008-09-16 |
2010-04-16 |
Genentech Inc |
Methods for treating progressive multiple sclerosis
|
AU2008221604B2
(en)
*
|
2008-09-22 |
2010-04-22 |
Commonwealth Scientific And Industrial Research Organisation |
Temperature-responsive polymer particles in protein separation applications
|
CA2739429C
(en)
|
2008-10-14 |
2020-12-22 |
Lisa A. Damico |
Immunoglobulin variants and uses thereof
|
MX2011004201A
(es)
|
2008-10-20 |
2011-05-24 |
Abbott Lab |
Desactivacion viral durante purificacion de anticuerpos.
|
TW201024318A
(en)
|
2008-10-20 |
2010-07-01 |
Abbott Lab |
Isolation and purification of antibodies using protein A affinity chromatography
|
CN118324847A
(zh)
*
|
2008-10-29 |
2024-07-12 |
阿布林克斯公司 |
单域抗原结合性分子的纯化方法
|
US20110313137A1
(en)
*
|
2009-02-25 |
2011-12-22 |
Dongxing Zha |
Her2 antibody compositions
|
TW201438739A
(zh)
|
2009-03-20 |
2014-10-16 |
Genentech Inc |
抗-her抗體
|
US8481694B2
(en)
*
|
2009-04-29 |
2013-07-09 |
Bio-Rad Laboratories, Inc. |
Purification of immunoconjugates
|
EP2435071A1
(en)
|
2009-05-29 |
2012-04-04 |
F. Hoffmann-La Roche AG |
Modulators for her2 signaling in her2 expressing patients with gastric cancer
|
DE202010018640U1
(de)
|
2009-07-24 |
2019-11-14 |
F. Hoffmann-La Roche Ag |
Rührersystem
|
BRPI1010119A2
(pt)
|
2009-07-24 |
2016-03-15 |
Hoffmann La Roche |
"método de produção de composição de anticorpo e uso de cromatografia de troca de íons analítica"
|
US9345661B2
(en)
|
2009-07-31 |
2016-05-24 |
Genentech, Inc. |
Subcutaneous anti-HER2 antibody formulations and uses thereof
|
PL2467399T3
(pl)
*
|
2009-08-20 |
2016-05-31 |
Baxalta Inc |
Oczyszczanie vWF zwiększające usuwanie wirusów bez otoczki lipidowej
|
RU2012112550A
(ru)
|
2009-09-01 |
2013-10-10 |
Эбботт Лэборетриз |
Иммуноглобулины с двумя вариабельными доменами и их применение
|
AR078161A1
(es)
|
2009-09-11 |
2011-10-19 |
Hoffmann La Roche |
Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento.
|
PT2483305T
(pt)
|
2009-10-01 |
2016-11-04 |
Hoffmann La Roche |
Filtração final de imunoglobulina em várias etapas
|
UY32948A
(es)
|
2009-10-15 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
US8304248B2
(en)
|
2009-11-16 |
2012-11-06 |
Torres Anthony R |
Protein separation via ion-exchange chromatography and associated methods, systems, and devices
|
US8697844B2
(en)
*
|
2009-11-24 |
2014-04-15 |
Novo Nordisk A/S |
Method of purifying pegylated proteins
|
US10087236B2
(en)
|
2009-12-02 |
2018-10-02 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
US11377485B2
(en)
|
2009-12-02 |
2022-07-05 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
WO2011069074A2
(en)
|
2009-12-04 |
2011-06-09 |
Genentech, Inc. |
Methods of treating metastatic breast cancer with trastuzumab-mcc-dm1
|
MX2012006406A
(es)
*
|
2009-12-04 |
2012-07-25 |
Genentech Inc |
Anticuerpos multiespecificos, analogos de anticuerpo, composiciones y metodos.
|
ES2651065T3
(es)
|
2009-12-18 |
2018-01-24 |
Novartis Ag |
Solución de lavado y método para cromatografía de afinidad
|
DK2536748T3
(da)
|
2010-02-18 |
2014-10-13 |
Genentech Inc |
Neuregulin-antagonister og anvendelse deraf ved behandling af kræft
|
WO2011130332A1
(en)
|
2010-04-12 |
2011-10-20 |
Academia Sinica |
Glycan arrays for high throughput screening of viruses
|
KR101152036B1
(ko)
|
2010-04-27 |
2012-06-08 |
(주)셀트리온 |
컬럼 순환 및 시료 연속주입법을 이용한 단백질 a 크로마토그래피 정제 방법
|
EP2975409B1
(en)
|
2010-05-10 |
2018-10-31 |
Academia Sinica |
Zanamivir phosphonate congeners with anti-influenza activity and determining oseltamivir susceptibility of influenza viruses
|
AU2011256727B2
(en)
*
|
2010-05-18 |
2015-08-13 |
Abbvie Inc. |
Apparatus and process of purification of proteins
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
KR101976853B1
(ko)
|
2010-05-25 |
2019-05-09 |
제넨테크, 인크. |
폴리펩티드의 정제 방법
|
US9187552B2
(en)
*
|
2010-05-27 |
2015-11-17 |
Merck Sharp & Dohme Corp. |
Method for preparing antibodies having improved properties
|
WO2012009705A1
(en)
|
2010-07-15 |
2012-01-19 |
Zyngenia, Inc. |
Ang-2 binding complexes and uses thereof
|
GB201012603D0
(en)
|
2010-07-27 |
2010-09-08 |
Ucb Pharma Sa |
Protein purification
|
PE20131412A1
(es)
|
2010-08-03 |
2014-01-19 |
Abbvie Inc |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
NZ604510A
(en)
|
2010-08-17 |
2013-10-25 |
Csl Ltd |
Dilutable biocidal compositions and methods of use
|
CN103260639A
(zh)
|
2010-08-26 |
2013-08-21 |
Abbvie公司 |
双重可变结构域免疫球蛋白及其用途
|
JPWO2012029990A1
(ja)
*
|
2010-09-01 |
2013-10-31 |
株式会社バイオマトリックス研究所 |
大腸がんマーカーに対する抗体
|
KR101584416B1
(ko)
|
2010-10-05 |
2016-01-13 |
에프. 호프만-라 로슈 아게 |
인간 tweak에 대한 항체 및 그의 용도
|
US20120264920A1
(en)
*
|
2010-10-11 |
2012-10-18 |
Abbott Laboratories |
Processes for purification of proteins
|
EP2643353A1
(en)
|
2010-11-24 |
2013-10-02 |
Novartis AG |
Multispecific molecules
|
US20120149878A1
(en)
*
|
2010-12-08 |
2012-06-14 |
Gillespie Ronald |
Protein purification
|
WO2012084829A1
(en)
|
2010-12-21 |
2012-06-28 |
F. Hoffmann-La Roche Ag |
Isoform enriched antibody preparation and method for obtaining it
|
EP2655413B1
(en)
|
2010-12-23 |
2019-01-16 |
F.Hoffmann-La Roche Ag |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
AU2012222312B2
(en)
*
|
2011-03-03 |
2017-06-08 |
Arla Foods Amba |
Method for isolating osteopontin using feeds containing cmp or casein species
|
EP2686016B1
(en)
|
2011-03-14 |
2019-05-01 |
Cellmid Limited |
Antibody recognizing n-domain of midkine
|
WO2012149197A2
(en)
|
2011-04-27 |
2012-11-01 |
Abbott Laboratories |
Methods for controlling the galactosylation profile of recombinantly-expressed proteins
|
ES2704038T3
(es)
|
2011-05-24 |
2019-03-13 |
Zyngenia Inc |
Complejos multiespecíficos multivalentes y monovalentes y sus usos
|
AU2012269720B2
(en)
|
2011-06-13 |
2015-01-22 |
Csl Limited |
Antibodies against G-CSFR and uses thereof
|
CN103890007A
(zh)
|
2011-08-17 |
2014-06-25 |
霍夫曼-拉罗奇有限公司 |
神经调节蛋白抗体及其用途
|
ES2548215T3
(es)
|
2011-10-05 |
2015-10-14 |
F. Hoffmann-La Roche Ag |
Proceso para la producción de anticuerpos de la glicoforma G1
|
EP4241849B1
(en)
*
|
2011-10-14 |
2024-09-18 |
F. Hoffmann-La Roche AG |
Uses for and article of manufacture including her2 dimerization inhibitor pertuzumab
|
US9327023B2
(en)
|
2011-10-25 |
2016-05-03 |
The Regents Of The University Of Michigan |
HER2 targeting agent treatment in non-HER2-amplified cancers having HER2 expressing cancer stem cells
|
WO2013059886A1
(en)
|
2011-10-28 |
2013-05-02 |
Patrys Limited |
Pat-lm1 epitopes and methods for using same
|
EP2773439A4
(en)
*
|
2011-10-31 |
2015-07-01 |
Merck Sharp & Dohme |
CHROMATOGRAPHY METHOD FOR RESOLVING HETEROGENIC ANTIBODY AGGREGATES
|
PL3257564T5
(pl)
*
|
2011-11-02 |
2024-10-07 |
F. Hoffmann-La Roche Ag |
Chromatografia elucyjna z przeładowaniem
|
CA2857114A1
(en)
|
2011-11-30 |
2013-06-06 |
Genentech, Inc. |
Erbb3 mutations in cancer
|
WO2013083810A1
(en)
|
2011-12-09 |
2013-06-13 |
F. Hoffmann-La Roche Ag |
Identification of non-responders to her2 inhibitors
|
US20130195851A1
(en)
|
2011-12-23 |
2013-08-01 |
Genentech, Inc. |
Articles of manufacture and methods for co-administration of antibodies
|
UY34558A
(es)
|
2011-12-30 |
2013-07-31 |
Abbvie Inc |
Proteínas de unión específicas duales dirigidas contra il-13 y/o il-17
|
CA2865082A1
(en)
|
2012-03-27 |
2013-10-03 |
Genentech, Inc. |
Diagnosis and treatments relating to her3 inhibitors
|
US10130714B2
(en)
|
2012-04-14 |
2018-11-20 |
Academia Sinica |
Enhanced anti-influenza agents conjugated with anti-inflammatory activity
|
US9505833B2
(en)
|
2012-04-20 |
2016-11-29 |
Abbvie Inc. |
Human antibodies that bind human TNF-alpha and methods of preparing the same
|
US9181572B2
(en)
|
2012-04-20 |
2015-11-10 |
Abbvie, Inc. |
Methods to modulate lysine variant distribution
|
US9067990B2
(en)
|
2013-03-14 |
2015-06-30 |
Abbvie, Inc. |
Protein purification using displacement chromatography
|
US9334319B2
(en)
|
2012-04-20 |
2016-05-10 |
Abbvie Inc. |
Low acidic species compositions
|
WO2013176754A1
(en)
|
2012-05-24 |
2013-11-28 |
Abbvie Inc. |
Novel purification of antibodies using hydrophobic interaction chromatography
|
HUE043552T2
(hu)
|
2012-06-08 |
2019-09-30 |
Sutro Biopharma Inc |
Antitestek, amelyek tartalmaznak helyspecifikus nem természetes aminosav maradékokat, eljárások elõállításukra és eljárások használatukra
|
EP3135690A1
(en)
*
|
2012-06-26 |
2017-03-01 |
Sutro Biopharma, Inc. |
Modified fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use
|
CA2880701A1
(en)
|
2012-08-18 |
2014-02-27 |
Academia Sinica |
Cell-permeable probes for identification and imaging of sialidases
|
EP2888238A4
(en)
|
2012-08-21 |
2016-01-27 |
Academia Sinica |
BENZOCYCLOOCTYN COMPOUNDS AND USES THEREOF
|
US9512214B2
(en)
|
2012-09-02 |
2016-12-06 |
Abbvie, Inc. |
Methods to control protein heterogeneity
|
AU2013309506A1
(en)
|
2012-09-02 |
2015-03-12 |
Abbvie Inc. |
Methods to control protein heterogeneity
|
AR093311A1
(es)
|
2012-11-01 |
2015-05-27 |
Abbvie Inc |
Inmunoglobulinas de dominio variable dual contra el factor de crecimiento endotelial vascular (vegf) y el ligando involucrado en la señalizacion celula a celula a traves del receptor notch (dll4)
|
MX363188B
(es)
|
2012-11-30 |
2019-03-13 |
Hoffmann La Roche |
Identificación de pacientes con necesidad de coterapia del inhibidor de pd-l1.
|
WO2014118685A2
(en)
*
|
2013-01-29 |
2014-08-07 |
Dr. Reddy's Laboratories Limited |
Method of altering the acidic variant content of antibody
|
SG11201505762XA
(en)
|
2013-02-07 |
2015-08-28 |
Csl Ltd |
Il-11r binding proteins and uses thereof
|
JP6608705B2
(ja)
|
2013-03-08 |
2019-11-20 |
ジェンザイム・コーポレーション |
治療用タンパク質の連続的な精製
|
US10023608B1
(en)
|
2013-03-13 |
2018-07-17 |
Amgen Inc. |
Protein purification methods to remove impurities
|
CN105073769B
(zh)
|
2013-03-14 |
2019-09-10 |
Emd密理博公司 |
利用基于a蛋白的色谱增加蛋白纯度的方法
|
US8921526B2
(en)
|
2013-03-14 |
2014-12-30 |
Abbvie, Inc. |
Mutated anti-TNFα antibodies and methods of their use
|
US9017687B1
(en)
|
2013-10-18 |
2015-04-28 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same using displacement chromatography
|
WO2014151878A2
(en)
|
2013-03-14 |
2014-09-25 |
Abbvie Inc. |
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
|
EA038918B1
(ru)
|
2013-03-15 |
2021-11-09 |
Зинджения, Инк. |
Пептид, связывающий рецептор эпидермального фактора роста, мультиспецифические комплексы, содержащие пептид и антитела, и их применение
|
WO2014144280A2
(en)
|
2013-03-15 |
2014-09-18 |
Abbvie Inc. |
DUAL SPECIFIC BINDING PROTEINS DIRECTED AGAINST IL-1β AND / OR IL-17
|
WO2014172371A2
(en)
|
2013-04-16 |
2014-10-23 |
Genentech, Inc. |
Pertuzumab variants and evaluation thereof
|
TWI596107B
(zh)
|
2013-06-25 |
2017-08-21 |
卡地拉保健有限公司 |
單株抗體之新穎純化方法
|
US10086054B2
(en)
|
2013-06-26 |
2018-10-02 |
Academia Sinica |
RM2 antigens and use thereof
|
EP3013347B1
(en)
|
2013-06-27 |
2019-12-11 |
Academia Sinica |
Glycan conjugates and use thereof
|
WO2015006555A2
(en)
|
2013-07-10 |
2015-01-15 |
Sutro Biopharma, Inc. |
Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
BR112016000231A8
(pt)
|
2013-07-12 |
2019-12-31 |
Genentech Inc |
métodos para identificações de condições de separação com cromatografia de troca de íons e para análises de composições de polipeptídeos
|
CN105682666B
(zh)
|
2013-09-06 |
2021-06-01 |
中央研究院 |
使用醣脂激活人类iNKT细胞
|
EP3048109A4
(en)
*
|
2013-09-17 |
2017-04-19 |
Kaneka Corporation |
Novel antibody purification method and antibody obtained therefrom, and novel antibody purification method using cation exchanger and antibody obtained therefrom
|
WO2015051293A2
(en)
|
2013-10-04 |
2015-04-09 |
Abbvie, Inc. |
Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
|
CN106029690B
(zh)
*
|
2013-10-18 |
2021-08-31 |
诺瓦塞浦加工有限公司 |
蛋白质纯化
|
US8946395B1
(en)
|
2013-10-18 |
2015-02-03 |
Abbvie Inc. |
Purification of proteins using hydrophobic interaction chromatography
|
US9181337B2
(en)
|
2013-10-18 |
2015-11-10 |
Abbvie, Inc. |
Modulated lysine variant species compositions and methods for producing and using the same
|
US9085618B2
(en)
|
2013-10-18 |
2015-07-21 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same
|
US10351592B2
(en)
*
|
2013-10-30 |
2019-07-16 |
Celltrion, Inc. |
Method for separating antibody isoforms using cation exchange chromatography
|
CN104628846B
(zh)
*
|
2013-11-06 |
2019-12-06 |
三生国健药业(上海)股份有限公司 |
重组蛋白质的纯化方法
|
US20150139988A1
(en)
|
2013-11-15 |
2015-05-21 |
Abbvie, Inc. |
Glycoengineered binding protein compositions
|
US10150818B2
(en)
|
2014-01-16 |
2018-12-11 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
WO2015109180A2
(en)
|
2014-01-16 |
2015-07-23 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
TWI709569B
(zh)
|
2014-01-17 |
2020-11-11 |
美商健臻公司 |
無菌層析樹脂及其用於製造方法的用途
|
TWI709570B
(zh)
|
2014-01-17 |
2020-11-11 |
美商健臻公司 |
無菌層析法及製法
|
TWI797430B
(zh)
|
2014-03-27 |
2023-04-01 |
中央研究院 |
反應性標記化合物及其用途
|
KR20160141857A
(ko)
|
2014-04-25 |
2016-12-09 |
제넨테크, 인크. |
트라스투주맙-mcc-dm1 및 퍼투주맙을 이용하는 초기 유방암의 치료방법
|
CN106661099A
(zh)
*
|
2014-05-27 |
2017-05-10 |
中央研究院 |
抗her2醣抗体及其用途
|
WO2015184004A1
(en)
|
2014-05-27 |
2015-12-03 |
Academia Sinica |
Anti-cd20 glycoantibodies and uses thereof
|
US10118969B2
(en)
|
2014-05-27 |
2018-11-06 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
TWI654202B
(zh)
|
2014-05-27 |
2019-03-21 |
中央研究院 |
增進抗體功效之通用糖型之組合物及方法
|
EP3154582A4
(en)
|
2014-05-28 |
2018-01-10 |
Academia Sinica |
Anti-tnf-alpha glycoantibodies and uses thereof
|
CN106794392A
(zh)
*
|
2014-06-25 |
2017-05-31 |
喜康生技公司 |
用于纯化蛋白质的方法和试剂
|
CN105315369B
(zh)
*
|
2014-07-25 |
2020-03-13 |
山东博安生物技术有限公司 |
利用阳离子交换层析纯化蛋白质
|
WO2016033245A1
(en)
|
2014-08-26 |
2016-03-03 |
Rmx, Llc |
Devices and methods for reducing intrathoracic pressure
|
TWI745275B
(zh)
|
2014-09-08 |
2021-11-11 |
中央研究院 |
使用醣脂激活人類iNKT細胞
|
JP2021006540A
(ja)
*
|
2014-09-10 |
2021-01-21 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
ガラクトース操作型免疫グロブリン1抗体
|
EP3567056A1
(en)
|
2014-09-10 |
2019-11-13 |
F. Hoffmann-La Roche AG |
Galactoengineered immunoglobulin 1 antibodies
|
SI3191135T1
(sl)
|
2014-09-12 |
2021-01-29 |
Genentech, Inc. |
Anti-HER2 protitelesa in imunokonjugati
|
KR20170055521A
(ko)
|
2014-09-17 |
2017-05-19 |
제넨테크, 인크. |
항-her2 항체를 포함하는 면역콘주게이트
|
AU2015336946A1
(en)
|
2014-10-23 |
2017-04-13 |
La Trobe University |
Fn14-binding proteins and uses thereof
|
KR20170078677A
(ko)
|
2014-11-06 |
2017-07-07 |
에프. 호프만-라 로슈 아게 |
Fcrn-결합이 개질된 fc-영역 변이체 및 이의 사용 방법
|
KR101531479B1
(ko)
*
|
2014-11-21 |
2015-06-26 |
세원셀론텍(주) |
의료용 재료로 사용하기 위한 고농도 콜라겐 제조방법
|
WO2016094881A2
(en)
|
2014-12-11 |
2016-06-16 |
Abbvie Inc. |
Lrp-8 binding proteins
|
EP3233120A4
(en)
|
2014-12-19 |
2018-05-30 |
Monash University |
Il-21 antibodies
|
CN105820251B
(zh)
*
|
2015-01-08 |
2019-10-15 |
江苏康宁杰瑞生物制药有限公司 |
具有共同轻链的双特异性抗体或抗体混合物
|
EP3242685B1
(en)
|
2015-01-09 |
2022-05-04 |
AdAlta Limited |
Cxcr4 binding molecules
|
US10495645B2
(en)
|
2015-01-16 |
2019-12-03 |
Academia Sinica |
Cancer markers and methods of use thereof
|
US9975965B2
(en)
|
2015-01-16 |
2018-05-22 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
EP3247718B1
(en)
*
|
2015-01-21 |
2021-09-01 |
Outlook Therapeutics, Inc. |
Modulation of charge variants in a monoclonal antibody composition
|
EP3789766A1
(en)
|
2015-01-24 |
2021-03-10 |
Academia Sinica |
Novel glycan conjugates and methods of use thereof
|
JP6807859B2
(ja)
*
|
2015-03-13 |
2021-01-06 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
クロマトグラフィーにおける不純物を取り除くためのアルカリ洗浄の使用
|
DK3302551T3
(da)
|
2015-05-30 |
2024-08-26 |
Hoffmann La Roche |
Fremgangsmåder til behandling af HER2-positiv tidligere ubehandlet metastatisk brystkræft
|
CN108064246A
(zh)
|
2015-06-15 |
2018-05-22 |
基因泰克公司 |
抗体和免疫结合物
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
JP6910339B2
(ja)
|
2015-07-07 |
2021-07-28 |
ジェネンテック, インコーポレイテッド |
抗her2抗体−薬物複合体とbcl−2阻害剤の併用療法
|
WO2017087280A1
(en)
|
2015-11-16 |
2017-05-26 |
Genentech, Inc. |
Methods of treating her2-positive cancer
|
WO2017084738A1
(en)
*
|
2015-11-18 |
2017-05-26 |
Merck Patent Gmbh |
Opposite ph-salt gradients for improved protein separations
|
CA3005483A1
(en)
*
|
2015-11-18 |
2017-05-26 |
Merck Patent Gmbh |
Improved protein separation in ion exchange chromatography
|
CA3011455A1
(en)
|
2016-01-27 |
2017-08-03 |
Sutro Biopharma, Inc. |
Anti-cd74 antibody conjugates, compositions comprising anti-cd74 antibody conjugates and methods of using anti-cd74 antibody conjugates
|
MX2018009341A
(es)
|
2016-02-03 |
2019-05-15 |
Oncobiologics Inc |
Formulaciones tamponadas para una mayor estabilidad de anticuerpos.
|
US10336784B2
(en)
|
2016-03-08 |
2019-07-02 |
Academia Sinica |
Methods for modular synthesis of N-glycans and arrays thereof
|
WO2017194554A1
(en)
|
2016-05-10 |
2017-11-16 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Combinations therapies for the treatment of cancer
|
EP3484911B1
(en)
|
2016-07-15 |
2020-11-04 |
H. Hoffnabb-La Roche Ag |
Method for purifying pegylated erythropoietin
|
JP7213549B2
(ja)
|
2016-08-22 |
2023-01-27 |
シーエイチオー ファーマ インコーポレイテッド |
抗体、結合性断片、および使用の方法
|
SG10201913263SA
(en)
|
2016-09-29 |
2020-03-30 |
Beijing Hanmi Pharmaceutical Co Ltd |
Heterodimeric immunoglobulin constructs and preparation methods thereof
|
CA3040913A1
(en)
|
2016-11-04 |
2018-05-11 |
Genentech, Inc. |
Treatment of her2-positive breast cancer
|
CA3043652A1
(en)
*
|
2016-11-18 |
2018-05-24 |
Beijing Hanmi Pharmaceutical Co., Ltd. |
Anti-pd-1/anti-her2 natural antibody structural heterodimeric bispecific antibody and method of preparing the same
|
KR102313262B1
(ko)
|
2016-12-28 |
2021-10-14 |
제넨테크, 인크. |
진행성 her2 발현 암의 치료
|
PT3570884T
(pt)
|
2017-01-17 |
2020-11-24 |
Hoffmann La Roche |
Formulações subcutâneas de anticorpo do her2
|
FI3589661T3
(fi)
|
2017-03-02 |
2024-01-31 |
Genentech Inc |
Her2-positiivisen rintasyövän adjuvanttihoito
|
EP3615695A1
(en)
|
2017-04-24 |
2020-03-04 |
Genentech, Inc. |
Erbb2/her2 mutations in the transmebrane or juxtamembrane domain
|
ES2999094T3
(en)
|
2017-09-11 |
2025-02-24 |
Univ Monash |
Binding proteins to the human thrombin receptor, par4
|
CN107602702A
(zh)
*
|
2017-09-22 |
2018-01-19 |
生标(上海)医疗器械科技有限公司 |
一种同时靶向人p185和血管内皮生长因子的抗体及其应用
|
CN108101987A
(zh)
*
|
2017-11-17 |
2018-06-01 |
安徽未名生物医药有限公司 |
一种重组抗TNF-α全人源单克隆抗体的纯化方法
|
WO2019104385A1
(en)
|
2017-11-29 |
2019-06-06 |
Csl Limited |
Method of treating or preventing ischemia-reperfusion injury
|
WO2019153200A1
(zh)
|
2018-02-08 |
2019-08-15 |
北京韩美药品有限公司 |
抗pd-1/抗her2天然抗体结构样异源二聚体形式双特异抗体及其制备
|
TWI841551B
(zh)
|
2018-03-13 |
2024-05-11 |
瑞士商赫孚孟拉羅股份公司 |
使用靶向4-1bb (cd137)之促效劑的組合療法
|
JP2021519790A
(ja)
|
2018-04-02 |
2021-08-12 |
アムジェン インコーポレイテッド |
エレヌマブ組成物及びその使用
|
CN111741979B
(zh)
|
2018-04-13 |
2024-07-02 |
豪夫迈·罗氏有限公司 |
包含4-1BBL的Her2靶向性抗原结合分子
|
US20210340279A1
(en)
|
2018-08-31 |
2021-11-04 |
Yale University |
Compositions and methods of using cell-penetrating antibodies in combination with immune checkpoint modulators
|
JP2021536353A
(ja)
|
2018-08-31 |
2021-12-27 |
ジェンザイム・コーポレーション |
無菌クロマトグラフィー樹脂および製造方法におけるその使用
|
TWI848832B
(zh)
|
2018-10-15 |
2024-07-11 |
美商建南德克公司 |
用曲妥珠單抗安坦辛治療殘存乳癌之方法
|
CN111196856A
(zh)
*
|
2018-11-19 |
2020-05-26 |
三生国健药业(上海)股份有限公司 |
抗her2/pd1双特异性抗体
|
CN113677403B
(zh)
|
2019-04-12 |
2024-12-27 |
豪夫迈·罗氏有限公司 |
包含脂质运载蛋白突变蛋白的双特异性抗原结合分子
|
WO2020234742A1
(en)
|
2019-05-20 |
2020-11-26 |
Lupin Limited |
Granulocyte colony stimulating factor purification
|
TW202112752A
(zh)
|
2019-06-13 |
2021-04-01 |
美商博特生物治療公司 |
胺基苯并氮呯化合物、免疫接合物及其用途
|
US11266838B1
(en)
|
2019-06-21 |
2022-03-08 |
Rmx, Llc |
Airway diagnostics utilizing phrenic nerve stimulation device and method
|
CN110339209B
(zh)
*
|
2019-07-18 |
2023-06-06 |
上海泰坦科技股份有限公司 |
一种去甲状腺结合蛋白的小牛血清的制备方法
|
CN114630684A
(zh)
|
2019-09-03 |
2022-06-14 |
博尔特生物治疗药物有限公司 |
氨基喹啉化合物、免疫缀合物及其用途
|
AU2020359446A1
(en)
|
2019-09-30 |
2022-04-21 |
Bolt Biotherapeutics, Inc. |
Amide-linked, aminobenzazepine immunoconjugates, and uses thereof
|
EP4045917A1
(en)
*
|
2019-10-14 |
2022-08-24 |
Pierce Biotechnology, Inc. |
Peptide purification formulations and methods
|
BR112022007719A2
(pt)
|
2019-10-25 |
2022-07-12 |
Bolt Biotherapeutics Inc |
Imunoconjugados, composto ligante, composição farmacêutica, método para tratar câncer, uso de um imunoconjugado e método de preparação de um imunoconjugado
|
CA3159770A1
(en)
|
2019-11-15 |
2021-05-20 |
Seagen Inc. |
Methods of treating her2 positive breast cancer with tucatinib in combination with an anti-her2 antibody-drug conjugate
|
WO2021119761A1
(en)
|
2019-12-20 |
2021-06-24 |
Hudson Institute of Medical Research |
Cxcl10 binding proteins and uses thereof
|
WO2021226440A1
(en)
|
2020-05-08 |
2021-11-11 |
Bolt Biotherapeutics, Inc. |
Elastase-substrate, peptide linker immunoconjugates, and uses thereof
|
PE20231361A1
(es)
|
2020-06-23 |
2023-09-05 |
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Moleculas agonistas de union al antigeno cd28 que se dirigen a her2
|
IL299376A
(en)
|
2020-06-29 |
2023-02-01 |
Genentech Inc |
Pertuzuniab plus trastuzumab fixed dose combination
|
AU2021308283A1
(en)
|
2020-07-14 |
2023-02-02 |
F. Hoffmann-La Roche Ag |
Assays for fixed dose combinations
|
EP4182475A2
(en)
|
2020-07-17 |
2023-05-24 |
Onena Medicines S.L. |
Antibodies against lefty proteins
|
CN116234586A
(zh)
|
2020-08-13 |
2023-06-06 |
博尔特生物治疗药物有限公司 |
吡唑并氮呯免疫缀合物及其用途
|
CN112430252B
(zh)
*
|
2020-11-13 |
2022-09-02 |
宜昌东阳光长江药业股份有限公司 |
一种提高目标蛋白回收率的层析方法
|
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(en)
|
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2023-10-18 |
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Anti-her2 immunoconjugates, and uses thereof
|
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(en)
|
2020-12-11 |
2022-06-16 |
Shelley Erin ACKERMAN |
Anti-her2 immunoconjugates, and uses thereof
|
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(en)
|
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2023-07-06 |
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Combination therapies for treatment of her2 cancer
|
AU2022245340A1
(en)
|
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2023-11-09 |
Bolt Biotherapeutics, Inc. |
2-amino-4-carboxamide-benzazepine immunoconjugates, and uses thereof
|
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(zh)
|
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2024-03-26 |
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2-氨基-4-甲酰胺-苯并氮杂卓免疫缀合物及其用途
|
MX2023011579A
(es)
|
2021-04-01 |
2023-10-10 |
Vestaron Corp |
Polipeptidos con mutaciones de av3 para el control de plagas.
|
CN113769794B
(zh)
*
|
2021-07-06 |
2024-04-05 |
沁浩膜技术(厦门)有限公司 |
一种连续脱除胞磷胆碱钠中杂质的离子交换系统及方法
|
US20250000995A1
(en)
|
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2025-01-02 |
Bolt Biotherapeutics, Inc. |
Tlr agonist immunoconjugates with cysteine-mutant antibodies, and uses thereof
|
WO2023122805A1
(en)
|
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2023-06-29 |
Vestaron Corporation |
Sorbitol driven selection pressure method
|
CN114230641B
(zh)
*
|
2021-12-29 |
2024-03-26 |
内蒙古必威安泰生物科技有限公司 |
一种去除口蹄疫抗原液中内毒素的方法
|
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(en)
|
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2023-10-05 |
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Combinations of av3 mutant polypeptides and bt toxins for pest control
|
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(en)
|
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Pesticidal actx peptide variants
|
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(en)
|
2022-06-17 |
2023-12-21 |
Vestaron Corporation |
Antimicrobial ncr13 variant peptides
|
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(en)
|
2022-07-29 |
2024-02-01 |
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Next Generation ACTX Peptides
|
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(es)
|
2022-08-18 |
2024-11-20 |
Immunocore Ltd |
Moléculas de unión multidominio
|
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(en)
|
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2024-02-22 |
Immunocore Limited |
Multi-domain binding molecules
|
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(en)
|
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2025-03-06 |
Immunocore Limited |
Multi-domain binding molecules
|
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(en)
|
2022-12-23 |
2024-06-27 |
Genentech, Inc. |
Cereblon degrader conjugates, and uses thereof
|
TW202434640A
(zh)
|
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2024-09-01 |
英商英美偌科有限公司 |
結合分子
|
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(en)
|
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2024-07-11 |
Immunocore Limited |
Binding molecules against a piwil1 peptide-hla complex
|
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(en)
|
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2024-08-22 |
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Aza-benzazepine immunoconjugates, and uses thereof
|
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(en)
|
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2024-09-12 |
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|
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(en)
|
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2023-06-14 |
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|