FI75163C - Foerfarande foer framstaellning av nya penemkarboxylsyror eller -estrar. - Google Patents

Foerfarande foer framstaellning av nya penemkarboxylsyror eller -estrar. Download PDF

Info

Publication number: FI75163C
Authority: FI; Finland
Prior art keywords: formula; compound; group; coor; same meaning
Prior art date: 1979-02-24

Application number

FI800493A

Other languages

English (en)

Finnish (fi)

Swedish (sv)

Other versions

FI75163B (fi

FI800493A (fi

Inventor

Federico Arcamone

Maurizio Foglio

Giovanni Franceschi

Aurora Sanfilippo

Cosimo Scarafile

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-02-24

Filing date

1980-02-19

Publication date

1988-05-09

1980-02-19 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1980-08-25 Publication of FI800493A publication Critical patent/FI800493A/fi

1988-01-29 Publication of FI75163B publication Critical patent/FI75163B/fi

1988-05-09 Application granted granted Critical

1988-05-09 Publication of FI75163C publication Critical patent/FI75163C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Cephalosporin Compounds (AREA)

FI800493A 1979-02-24 1980-02-19 Foerfarande foer framstaellning av nya penemkarboxylsyror eller -estrar. FI75163C (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB7906634		1979-02-24
GB7906634		1979-02-24
GB7932591		1979-09-20
GB7932591		1979-09-20

Publications (3)

Publication Number	Publication Date
FI800493A FI800493A (fi)	1980-08-25
FI75163B FI75163B (fi)	1988-01-29
FI75163C true FI75163C (fi)	1988-05-09

Family

ID=26270697

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI800493A FI75163C (fi)	1979-02-24	1980-02-19	Foerfarande foer framstaellning av nya penemkarboxylsyror eller -estrar.

Country Status (24)

Country	Link
AT (1)	AT368506B (fr)
AU (1)	AU535080B2 (fr)
CA (2)	CA1154010A (fr)
CH (2)	CH654831A5 (fr)
CS (1)	CS226010B2 (fr)
DE (1)	DE3006273A1 (fr)
DK (1)	DK159448C (fr)
ES (2)	ES8200685A1 (fr)
FI (1)	FI75163C (fr)
FR (1)	FR2449690B1 (fr)
GB (1)	GB2043639B (fr)
GR (1)	GR73623B (fr)
HK (1)	HK74487A (fr)
HU (1)	HU182664B (fr)
IE (1)	IE49407B1 (fr)
IT (1)	IT1193922B (fr)
LU (1)	LU82192A1 (fr)
NL (1)	NL192265C (fr)
NO (1)	NO161000C (fr)
NZ (1)	NZ192949A (fr)
PT (1)	PT70849A (fr)
SE (1)	SE449489B (fr)
UA (1)	UA6041A1 (fr)
YU (1)	YU42964B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5625110A (en) *	1978-12-18	1981-03-10	Bristol Myers Co	Antibacterial
DE3121510A1 (de) *	1980-07-04	1982-06-16	Farmitalia Carlo Erba S.p.A., 20159 Milano	6-alkyl-2-subst.-peneme und verfahren zu ihrer herstellung
JPS588084A (ja) *	1981-07-08	1983-01-18	Takeda Chem Ind Ltd	（６ｒ）−置換−（５ｒ）−ペネム−３−カルボン酸誘導体およびその製造法
EP0180252B1 (fr) *	1981-07-15	1989-04-26	Sumitomo Pharmaceuticals Company, Limited	Procédé de préparation de dérivés d'azétidinone
SU1389680A3 (ru) *	1981-12-11	1988-04-15	Фармиталия Карло Эрба С.П.А. (Фирма)	Способ получени оптически активных пенемов или их солей с щелочными металлами
NO831160L (no) *	1982-04-08	1983-10-10	Erba Farmitalia	Fremstilling av substituerte penem-derivater
PH21930A (en) *	1982-11-16	1988-04-08	Ciba Geigy Ag	6-hydroxy-lower alkylpenem compounds,pharmaceutical composition containing same and method of use thereof
EP0112283B1 (fr) *	1982-11-16	1987-08-12	Ciba-Geigy Ag	Dérivés hétérocyclylthio, procédé pour leur préparation, compositions pharmaceutiques les contenant et leur application
GB8300295D0 (en) *	1983-01-06	1983-02-09	Erba Farmitalia	Penem esters
JPS59152387A (ja) *	1983-02-10	1984-08-31	Shionogi & Co Ltd	新規ペネム化合物
GB8321677D0 (en) *	1983-08-11	1983-09-14	Erba Farmitalia	Preparation of penems
US4656165A (en) *	1983-09-02	1987-04-07	Ciba-Geigy Corporation	Aminomethyl penem compounds
US4711886A (en) *	1984-07-02	1987-12-08	Merck & Co., Inc.	β-lactam derivatives as anti-inflammatory and antidegenerative agents
US4761408A (en) *	1984-11-02	1988-08-02	Ciba-Geigy Corporation	Crystalline aminomethyl compound
DE3882730D1 (de) *	1987-02-11	1993-09-09	Ciba Geigy Ag	Bicyclische beta-lactam-carbonsaeuren.
US5364768A (en) *	1987-07-07	1994-11-15	Farmitalia Carlo Erba S.R.L.	Process for the preparation of penems
GB2206578B (en) *	1987-07-07	1991-07-03	Erba Carlo Spa	Process for the preparation of penems
IT1286558B1 (it) *	1996-02-27	1998-07-15	Menarini Farma Ind	Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici
DE69805975T2 (de)	1997-12-29	2002-12-19	Research Corp. Technologies, Inc.	2-beta-substituierte-6-alkylidenpenizillansäure-derivate als beta-laktamase inhibitoren
US6407091B1 (en)	1999-04-15	2002-06-18	Research Corporation Technologies, Inc.	β-lactamase inhibiting compounds
US6720445B2 (en)	2000-12-21	2004-04-13	Beacon Laboratories, Inc.	Acetyloxymethyl esters and methods for using the same
DE60214740T2 (de)	2001-07-24	2007-10-04	Southern Methodist University Foundation for Research, Dallas	3-substituierte 7-alkylidene-3-cephem-4-carbonsäuren als beta-lactamase inhibitoren
US7022691B2 (en)	2002-04-04	2006-04-04	John D. Buynak	Inhibitors of serine and metallo-β-lactamases

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
LU77306A1 (fr) *	1977-05-09	1979-01-18
AU3796278A (en) *	1977-07-13	1980-01-17	Glaxo Group Ltd	Penams and azetidinones
US4168314A (en) *	1977-11-17	1979-09-18	Merck & Co., Inc.	6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
US4155912A (en) *	1977-12-14	1979-05-22	Bristol-Myers Company	2-Methylpenem-3-carboxylic acid antibiotics
EP0003415A3 (fr) *	1978-01-20	1979-08-22	Glaxo Group Limited	Composés bêta-lactames, procédés pour leur préparation, compositions pharmaceutiques les contenant et les intermédiaires pour leur préparation
EP0042026B1 (fr) *	1978-02-02	1986-01-08	Ciba-Geigy Ag	Dérivés d'azétidin-2-one 3,4-disubstitués et procédé de préparation
EP0010358A1 (fr) *	1978-09-20	1980-04-30	Glaxo Group Limited	Composés de bêta-lactame, procédés pour leur préparation, compositions les contenant, intermédiaires utilisables dans leur préparation et méthodes pour leur production
JPS5625110A (en) *	1978-12-18	1981-03-10	Bristol Myers Co	Antibacterial
EP0013067A1 (fr) *	1978-12-22	1980-07-09	Beecham Group Plc	Agents antibactériens à cycle bêta-lactame bicyclique, leur utilisation dans des compositions pharmaceutiques, procédés pour leur préparation et intermédiaires à utiliser dans de tels procédés

1980
- 1980-02-19 FI FI800493A patent/FI75163C/fi not_active IP Right Cessation
- 1980-02-19 GR GR61228A patent/GR73623B/el unknown
- 1980-02-19 GB GB8005476A patent/GB2043639B/en not_active Expired
- 1980-02-19 IT IT20021/80A patent/IT1193922B/it active
- 1980-02-19 AU AU55670/80A patent/AU535080B2/en not_active Ceased
- 1980-02-19 NL NL8001012A patent/NL192265C/nl not_active IP Right Cessation
- 1980-02-19 AT AT0091980A patent/AT368506B/de not_active IP Right Cessation
- 1980-02-20 DE DE19803006273 patent/DE3006273A1/de active Granted
- 1980-02-20 CA CA000346011A patent/CA1154010A/fr not_active Expired
- 1980-02-20 PT PT70849A patent/PT70849A/pt not_active IP Right Cessation
- 1980-02-20 IE IE338/80A patent/IE49407B1/en not_active IP Right Cessation
- 1980-02-20 YU YU461/80A patent/YU42964B/xx unknown
- 1980-02-21 CH CH2794/84A patent/CH654831A5/de not_active IP Right Cessation
- 1980-02-21 CH CH1400/80A patent/CH651570A5/de not_active IP Right Cessation
- 1980-02-22 SE SE8001424A patent/SE449489B/sv not_active IP Right Cessation
- 1980-02-22 CS CS801241A patent/CS226010B2/cs unknown
- 1980-02-22 LU LU82192A patent/LU82192A1/fr unknown
- 1980-02-22 NZ NZ192949A patent/NZ192949A/en unknown
- 1980-02-22 NO NO800501A patent/NO161000C/no unknown
- 1980-02-22 FR FR8003938A patent/FR2449690B1/fr not_active Expired
- 1980-02-22 DK DK077580A patent/DK159448C/da not_active IP Right Cessation
- 1980-02-22 HU HU80420A patent/HU182664B/hu not_active IP Right Cessation
- 1980-02-22 UA UA2886007A patent/UA6041A1/uk unknown
- 1980-02-23 ES ES488886A patent/ES8200685A1/es not_active Expired
- 1980-10-16 ES ES495977A patent/ES8107224A1/es not_active Expired
1986
- 1986-01-14 CA CA000499579A patent/CA1212665B/fr not_active Expired
1987
- 1987-10-15 HK HK744/87A patent/HK74487A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
FR2449690A1 (fr)	1980-09-19
CS226010B2 (en)	1984-03-19
ES495977A0 (es)	1981-10-01
IT1193922B (it)	1988-08-31
CH651570A5 (de)	1985-09-30
IT8020021A0 (it)	1980-02-19
DK159448C (da)	1991-03-04
NZ192949A (en)	1984-03-16
DE3006273A1 (de)	1980-09-04
AU535080B2 (en)	1984-03-01
IE800338L (en)	1980-08-24
ATA91980A (de)	1982-02-15
FI75163B (fi)	1988-01-29
SE449489B (sv)	1987-05-04
CH654831A5 (de)	1986-03-14
GB2043639A (en)	1980-10-08
SE8001424L (sv)	1980-08-25
PT70849A (en)	1980-03-01
YU42964B (en)	1989-02-28
FI800493A (fi)	1980-08-25
ES8107224A1 (es)	1981-10-01
HU182664B (en)	1984-02-28
FR2449690B1 (fr)	1986-06-13
GB2043639B (en)	1983-07-20
AU5567080A (en)	1980-09-11
NL192265B (nl)	1996-12-02
IT8020021A1 (it)	1981-08-19
LU82192A1 (fr)	1980-06-06
DK77580A (da)	1980-08-25
AT368506B (de)	1982-10-25
NO161000B (no)	1989-03-13
HK74487A (en)	1987-10-23
NO161000C (no)	1989-06-21
ES488886A0 (es)	1981-11-16
IE49407B1 (en)	1985-10-02
NL192265C (nl)	1997-04-03
UA6041A1 (uk)	1994-12-29
NL8001012A (nl)	1980-08-26
GR73623B (fr)	1984-03-26
YU46180A (en)	1983-02-28
DK159448B (da)	1990-10-15
CA1212665B (fr)	1986-10-14
NO800501L (no)	1980-08-25
CA1154010A (fr)	1983-09-20
ES8200685A1 (es)	1981-11-16

Publication	Publication Date	Title
FI75163C (fi)	1988-05-09	Foerfarande foer framstaellning av nya penemkarboxylsyror eller -estrar.
Leanza et al.	1983	An efficient synthesis of 2-substituted-thio-6-hydroxyethyl-penem-3-carboxylic acids via 2-thioxopenams
FI83521C (fi)	1991-07-25	Foerfarande foer framstaellning av penemer.
SK435990A3 (en)	1998-01-14	10-(1-hydroxyethyl)-11-oxo-1-azatricyclo£7.2.0.03,8\|-undec-2-ene- -2-carboxylic acid, producing method, pharmaceutical composition containing the same and its use
US4482565A (en)	1984-11-13	β-Lactam-containing antibacterial agents and β-lactamase inhibitors
OA10064A (fr)	1996-10-14	Derives de la cephalosporine compositions pharmaceutiques les contenant et procede de fabrication
JP3080692B2 (ja)	2000-08-28	第四アンモニウムで置換されたプロペニル基を３位置に有する新規なセファロスポリン類、それらの製造法、それらの薬剤としての使用、それらを含む組成物及び新規な中間体
US4155912A (en)	1979-05-22	2-Methylpenem-3-carboxylic acid antibiotics
JPS59108789A (ja)	1984-06-23	ペネム化合物の製法
JP2547341B2 (ja)	1996-10-23	２−メトキシメチルペネム化合物
KR840000865B1 (ko)	1984-06-20	β-락탐-함유 항균제의 제조방법
JPS63162694A (ja)	1988-07-06	ペネム誘導体、その製造法およびその用途
US4558042A (en)	1985-12-10	β-Lactam-containing antibacterial agents and β-lactamase inhibitors
US5811419A (en)	1998-09-22	Isooxacephem-derivatives
US4616084A (en)	1986-10-07	Process for the preparation of 7-acylamino-3-hydroxy-cephem-4-carboxylic acids and 7-acylamino-3-hydroxy-1-dethia-1-oxacephem-4-carboxylic acids
FR2534253A1 (fr)	1984-04-13	Acide azetidinyl sulfonique et analogues, a action therapeutique
JP2922220B2 (ja)	1999-07-19	ペネムの製法
JPH06211860A (ja)	1994-08-02	カルバペネム、カルバペネムを含有する抗菌性の製薬学的組成物、その製造方法およびその製造のための中間生成物
US4293495A (en)	1981-10-06	Symmetrical azetidinone aldehyde disulfides and process
FR2590256A1 (fr)	1987-05-22	Carbamoyloxymethylalkylcarbapenemes, leur procede de preparation
GB2207133A (en)	1989-01-25	Penem derivatives
US4394313A (en)	1983-07-19	Symmetrical azetidinone aldehyde disulfides and process
JP3522758B2 (ja)	2004-04-26	４−（ホルミルチオ）−アゼチジン−２−オン誘導体およびペネム誘導体の製造方法
HU209817B (en)	1994-11-28	Process for the production of antibacterial 2-carbapenem derivatives
JPS62212388A (ja)	1987-09-18	（１ｒ）−１−置換カルバペネム−３−カルボン酸誘導体

Legal Events

Date	Code	Title	Description
1997-09-09	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: FARMITALIA CARLO ERBA S.R.L