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ES8200685A1 - Un procedimiento para la preparacion de derivados acidos penemcarboxilicos. - Google Patents

Un procedimiento para la preparacion de derivados acidos penemcarboxilicos.

Info

Publication number
ES8200685A1
ES8200685A1 ES488886A ES488886A ES8200685A1 ES 8200685 A1 ES8200685 A1 ES 8200685A1 ES 488886 A ES488886 A ES 488886A ES 488886 A ES488886 A ES 488886A ES 8200685 A1 ES8200685 A1 ES 8200685A1
Authority
ES
Spain
Prior art keywords
lower alkyl
optionally substituted
substituted methyl
esters
penem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES488886A
Other languages
English (en)
Spanish (es)
Other versions
ES488886A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of ES488886A0 publication Critical patent/ES488886A0/es
Publication of ES8200685A1 publication Critical patent/ES8200685A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
ES488886A 1979-02-24 1980-02-23 Un procedimiento para la preparacion de derivados acidos penemcarboxilicos. Expired ES8200685A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7906634 1979-02-24
GB7932591 1979-09-20

Publications (2)

Publication Number Publication Date
ES488886A0 ES488886A0 (es) 1981-11-16
ES8200685A1 true ES8200685A1 (es) 1981-11-16

Family

ID=26270697

Family Applications (2)

Application Number Title Priority Date Filing Date
ES488886A Expired ES8200685A1 (es) 1979-02-24 1980-02-23 Un procedimiento para la preparacion de derivados acidos penemcarboxilicos.
ES495977A Expired ES8107224A1 (es) 1979-02-24 1980-10-16 Un procedimiento para la preparacion de derivados acidos penem-carboxilicos

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES495977A Expired ES8107224A1 (es) 1979-02-24 1980-10-16 Un procedimiento para la preparacion de derivados acidos penem-carboxilicos

Country Status (24)

Country Link
AT (1) AT368506B (fr)
AU (1) AU535080B2 (fr)
CA (2) CA1154010A (fr)
CH (2) CH654831A5 (fr)
CS (1) CS226010B2 (fr)
DE (1) DE3006273A1 (fr)
DK (1) DK159448C (fr)
ES (2) ES8200685A1 (fr)
FI (1) FI75163C (fr)
FR (1) FR2449690B1 (fr)
GB (1) GB2043639B (fr)
GR (1) GR73623B (fr)
HK (1) HK74487A (fr)
HU (1) HU182664B (fr)
IE (1) IE49407B1 (fr)
IT (1) IT1193922B (fr)
LU (1) LU82192A1 (fr)
NL (1) NL192265C (fr)
NO (1) NO161000C (fr)
NZ (1) NZ192949A (fr)
PT (1) PT70849A (fr)
SE (1) SE449489B (fr)
UA (1) UA6041A1 (fr)
YU (1) YU42964B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
DE3121510A1 (de) * 1980-07-04 1982-06-16 Farmitalia Carlo Erba S.p.A., 20159 Milano 6-alkyl-2-subst.-peneme und verfahren zu ihrer herstellung
JPS588084A (ja) * 1981-07-08 1983-01-18 Takeda Chem Ind Ltd （６ｒ）−置換−（５ｒ）−ペネム−３−カルボン酸誘導体およびその製造法
EP0180252B1 (fr) * 1981-07-15 1989-04-26 Sumitomo Pharmaceuticals Company, Limited Procédé de préparation de dérivés d'azétidinone
SU1389680A3 (ru) * 1981-12-11 1988-04-15 Фармиталия Карло Эрба С.П.А. (Фирма) Способ получени оптически активных пенемов или их солей с щелочными металлами
NO831160L (no) * 1982-04-08 1983-10-10 Erba Farmitalia Fremstilling av substituerte penem-derivater
PH21930A (en) * 1982-11-16 1988-04-08 Ciba Geigy Ag 6-hydroxy-lower alkylpenem compounds,pharmaceutical composition containing same and method of use thereof
EP0112283B1 (fr) * 1982-11-16 1987-08-12 Ciba-Geigy Ag Dérivés hétérocyclylthio, procédé pour leur préparation, compositions pharmaceutiques les contenant et leur application
GB8300295D0 (en) * 1983-01-06 1983-02-09 Erba Farmitalia Penem esters
JPS59152387A (ja) * 1983-02-10 1984-08-31 Shionogi & Co Ltd 新規ペネム化合物
GB8321677D0 (en) * 1983-08-11 1983-09-14 Erba Farmitalia Preparation of penems
US4656165A (en) * 1983-09-02 1987-04-07 Ciba-Geigy Corporation Aminomethyl penem compounds
US4711886A (en) * 1984-07-02 1987-12-08 Merck & Co., Inc. β-lactam derivatives as anti-inflammatory and antidegenerative agents
US4761408A (en) * 1984-11-02 1988-08-02 Ciba-Geigy Corporation Crystalline aminomethyl compound
DE3882730D1 (de) * 1987-02-11 1993-09-09 Ciba Geigy Ag Bicyclische beta-lactam-carbonsaeuren.
US5364768A (en) * 1987-07-07 1994-11-15 Farmitalia Carlo Erba S.R.L. Process for the preparation of penems
GB2206578B (en) * 1987-07-07 1991-07-03 Erba Carlo Spa Process for the preparation of penems
IT1286558B1 (it) * 1996-02-27 1998-07-15 Menarini Farma Ind Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici
DE69805975T2 (de) 1997-12-29 2002-12-19 Research Corp. Technologies, Inc. 2-beta-substituierte-6-alkylidenpenizillansäure-derivate als beta-laktamase inhibitoren
US6407091B1 (en) 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds
US6720445B2 (en) 2000-12-21 2004-04-13 Beacon Laboratories, Inc. Acetyloxymethyl esters and methods for using the same
DE60214740T2 (de) 2001-07-24 2007-10-04 Southern Methodist University Foundation for Research, Dallas 3-substituierte 7-alkylidene-3-cephem-4-carbonsäuren als beta-lactamase inhibitoren
US7022691B2 (en) 2002-04-04 2006-04-04 John D. Buynak Inhibitors of serine and metallo-β-lactamases

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU77306A1 (fr) * 1977-05-09 1979-01-18
AU3796278A (en) * 1977-07-13 1980-01-17 Glaxo Group Ltd Penams and azetidinones
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
US4155912A (en) * 1977-12-14 1979-05-22 Bristol-Myers Company 2-Methylpenem-3-carboxylic acid antibiotics
EP0003415A3 (fr) * 1978-01-20 1979-08-22 Glaxo Group Limited Composés bêta-lactames, procédés pour leur préparation, compositions pharmaceutiques les contenant et les intermédiaires pour leur préparation
EP0042026B1 (fr) * 1978-02-02 1986-01-08 Ciba-Geigy Ag Dérivés d'azétidin-2-one 3,4-disubstitués et procédé de préparation
EP0010358A1 (fr) * 1978-09-20 1980-04-30 Glaxo Group Limited Composés de bêta-lactame, procédés pour leur préparation, compositions les contenant, intermédiaires utilisables dans leur préparation et méthodes pour leur production
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
EP0013067A1 (fr) * 1978-12-22 1980-07-09 Beecham Group Plc Agents antibactériens à cycle bêta-lactame bicyclique, leur utilisation dans des compositions pharmaceutiques, procédés pour leur préparation et intermédiaires à utiliser dans de tels procédés

Also Published As

Publication number Publication date
FR2449690A1 (fr) 1980-09-19
CS226010B2 (en) 1984-03-19
ES495977A0 (es) 1981-10-01
IT1193922B (it) 1988-08-31
CH651570A5 (de) 1985-09-30
IT8020021A0 (it) 1980-02-19
DK159448C (da) 1991-03-04
NZ192949A (en) 1984-03-16
DE3006273A1 (de) 1980-09-04
AU535080B2 (en) 1984-03-01
IE800338L (en) 1980-08-24
ATA91980A (de) 1982-02-15
FI75163B (fi) 1988-01-29
SE449489B (sv) 1987-05-04
CH654831A5 (de) 1986-03-14
FI75163C (fi) 1988-05-09
GB2043639A (en) 1980-10-08
SE8001424L (sv) 1980-08-25
PT70849A (en) 1980-03-01
YU42964B (en) 1989-02-28
FI800493A (fi) 1980-08-25
ES8107224A1 (es) 1981-10-01
HU182664B (en) 1984-02-28
FR2449690B1 (fr) 1986-06-13
GB2043639B (en) 1983-07-20
AU5567080A (en) 1980-09-11
NL192265B (nl) 1996-12-02
IT8020021A1 (it) 1981-08-19
LU82192A1 (fr) 1980-06-06
DK77580A (da) 1980-08-25
AT368506B (de) 1982-10-25
NO161000B (no) 1989-03-13
HK74487A (en) 1987-10-23
NO161000C (no) 1989-06-21
ES488886A0 (es) 1981-11-16
IE49407B1 (en) 1985-10-02
NL192265C (nl) 1997-04-03
UA6041A1 (uk) 1994-12-29
NL8001012A (nl) 1980-08-26
GR73623B (fr) 1984-03-26
YU46180A (en) 1983-02-28
DK159448B (da) 1990-10-15
CA1212665B (fr) 1986-10-14
NO800501L (no) 1980-08-25
CA1154010A (fr) 1983-09-20

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