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ES2166749T3 - Diagnosticos de nanbv: polinucleotidos utiles para discriminar virus de la hepatitis c. - Google Patents

Diagnosticos de nanbv: polinucleotidos utiles para discriminar virus de la hepatitis c.

Info

Publication number
ES2166749T3
ES2166749T3 ES90305421T ES90305421T ES2166749T3 ES 2166749 T3 ES2166749 T3 ES 2166749T3 ES 90305421 T ES90305421 T ES 90305421T ES 90305421 T ES90305421 T ES 90305421T ES 2166749 T3 ES2166749 T3 ES 2166749T3
Authority
ES
Spain
Prior art keywords
polinucleotides
discriminate
useful
hepatitis viruses
hcv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90305421T
Other languages
English (en)
Inventor
Michael Houghton
Qui-Lim Choo
George Kuo
Jang Han
Michael S Urdea
Amy J Weiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Application granted granted Critical
Publication of ES2166749T3 publication Critical patent/ES2166749T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

EL INVENTOR HA DECUBIERTO UN NUEVO VIRUS, EL VIRUS DE LA HEPATITIS C (HCV), QUE HA DEMOSTRADO SER EL PRINCIPAL AGENTE ETIOLOGICO DEL NANBH DE LA SANGRE. SE PROPORCIONAN REAGENTES PARA AISLAR, AMPLIFICAR Y DETECTAR LOS POLINUCLEOTIDOS DEL HCV. ESTOS REAGENTES SON OLIGOMEROS COMPUESTOS POR SECUENCIAS POLINUCLEOTIDAS QUE SON CAPACES DE FORMAR ESTRUCTURAS HIBRIDAS CON SECUENCIAS POLINUCLEOTIDAS DE HCV.
ES90305421T 1989-05-18 1990-05-18 Diagnosticos de nanbv: polinucleotidos utiles para discriminar virus de la hepatitis c. Expired - Lifetime ES2166749T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35596189A 1989-05-18 1989-05-18
US45663789A 1989-12-21 1989-12-21
US50543590A 1990-04-04 1990-04-04

Publications (1)

Publication Number Publication Date
ES2166749T3 true ES2166749T3 (es) 2002-05-01

Family

ID=27408242

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90305421T Expired - Lifetime ES2166749T3 (es) 1989-05-18 1990-05-18 Diagnosticos de nanbv: polinucleotidos utiles para discriminar virus de la hepatitis c.

Country Status (17)

Country Link
EP (1) EP0398748B1 (es)
JP (3) JP2656996B2 (es)
AT (1) ATE211772T1 (es)
AU (1) AU638719B2 (es)
BG (1) BG60348B2 (es)
CA (1) CA2017157C (es)
DE (1) DE69033891T2 (es)
DK (1) DK0398748T3 (es)
ES (1) ES2166749T3 (es)
FI (1) FI105279B (es)
GE (1) GEP20002164B (es)
HU (1) HUT59964A (es)
LV (1) LV10729B (es)
MC (1) MC2188A1 (es)
NO (1) NO303503B1 (es)
RO (1) RO113059B1 (es)
WO (1) WO1990014436A1 (es)

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US5747339A (en) 1990-06-25 1998-05-05 Research Foundation For Microbial Diseases Of Osaka Non-A, non-B hepatitis virus genomic CDNA and antigen polypeptide
AU7967191A (en) * 1990-06-30 1992-01-23 Akzo N.V. Non-a non-b sequences
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US5922857A (en) * 1992-09-28 1999-07-13 Chiron Corporation Methods and compositions for controlling translation of HCV proteins
JPH06153961A (ja) * 1992-11-27 1994-06-03 Imuno Japan:Kk Ｃ型肝炎ウイルス部分遺伝子、ならびにｃ型肝炎ウイルス遺 伝子の高感度検出法
DE69433160T2 (de) 1993-05-12 2004-07-08 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Konserviertes Motiv der Hepatitis C Virus E2/NS1 Region
AU3241095A (en) * 1994-07-29 1996-03-04 Chiron Corporation Novel hepatitis c e1 and e2 truncated polypeptides and methods of obtaining the same
JP3793571B2 (ja) 1994-07-29 2006-07-05 カイロン コーポレイション 新規ｃ型肝炎ｅ１およびｅ２短縮型ポリペプチドならびにこれらを得る方法
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ES2328536T3 (es) 1997-05-06 2009-11-13 Novartis Vaccines And Diagnostics, Inc. Produccion intracelular de polipeptido e2 truncado de la hepatitis c.
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Also Published As

Publication number Publication date
DK0398748T3 (da) 2002-03-18
DE69033891T2 (de) 2002-08-29
EP0398748A2 (en) 1990-11-22
LV10729A (lv) 1995-06-20
CA2017157C (en) 2003-07-29
AU5812390A (en) 1990-12-18
RO113059B1 (ro) 1998-03-30
JP3701754B2 (ja) 2005-10-05
LV10729B (en) 1995-12-20
HUT59964A (en) 1992-07-28
AU638719B2 (en) 1993-07-08
ATE211772T1 (de) 2002-01-15
JPH05500155A (ja) 1993-01-21
JPH1089A (ja) 1998-01-06
DE69033891D1 (de) 2002-02-21
GEP20002164B (en) 2000-07-10
WO1990014436A1 (en) 1990-11-29
EP0398748A3 (en) 1991-10-23
CA2017157A1 (en) 1990-11-18
MC2188A1 (fr) 1992-09-16
NO914517L (no) 1992-01-16
NO914517D0 (no) 1991-11-18
BG60348B2 (bg) 1994-09-30
NO303503B1 (no) 1998-07-20
FI105279B (fi) 2000-07-14
HU904754D0 (en) 1992-01-28
FI915443A0 (fi) 1991-11-18
JPH10113176A (ja) 1998-05-06
EP0398748B1 (en) 2002-01-09
JP2656996B2 (ja) 1997-09-24
JP3698520B2 (ja) 2005-09-21

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