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ES2138784T3 - Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c. - Google Patents

Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.

Info

Publication number
ES2138784T3
ES2138784T3 ES96201157T ES96201157T ES2138784T3 ES 2138784 T3 ES2138784 T3 ES 2138784T3 ES 96201157 T ES96201157 T ES 96201157T ES 96201157 T ES96201157 T ES 96201157T ES 2138784 T3 ES2138784 T3 ES 2138784T3
Authority
ES
Spain
Prior art keywords
detection
hcv
hepatitis
virus
antibodies against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96201157T
Other languages
English (en)
Inventor
Robert J Deleys
Dirk Pollet
Geert Maertens
Heuverswyn Hugo Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Europe NV SA
Original Assignee
Innogenetics NV SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26125651&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2138784(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Innogenetics NV SA filed Critical Innogenetics NV SA
Application granted granted Critical
Publication of ES2138784T3 publication Critical patent/ES2138784T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/82—Hepatitis associated antigens and antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

SE PROPORCIONAN SECUENCIAS DE PEPTIDOS QUE SON CAPACES DE IMITAR PROTEINAS CODIFICADAS POR HCV PARA USAR COMO REACTIVOS PARA LA DETECCION EN LA SANGRE O PRODUCTOS DE SANGRE DE UNA EXPOSICION PREVIA A HCV. LOS PEPTIDOS SON AL MENOS DE UNA LONGITUD DE 5 AMINOACIDOS Y PUEDEN SER USADOS EN VARIOS ENSAYOS ESPECIFICOS PARA LA DETECCION DE ANTICUERPOS PARA HCV, PARA LA DETECCION DE ANTIGENOS DE HCV, O COMO INMUNOGENOS.
ES96201157T 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c. Expired - Lifetime ES2138784T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG1996005024A SG47062A1 (en) 1990-12-14 1990-12-14 Synthetic antigens for the detection of antibodies to hepatitis virus
EP90124241A EP0489968B1 (en) 1990-12-14 1990-12-14 Synthetic antigens for the detection of antibodies to hepatitis C virus

Publications (1)

Publication Number Publication Date
ES2138784T3 true ES2138784T3 (es) 2000-01-16

Family

ID=26125651

Family Applications (3)

Application Number Title Priority Date Filing Date
ES90124241T Expired - Lifetime ES2095852T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.
ES94108611T Expired - Lifetime ES2101388T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos para el virus de la hepatitis c.
ES96201157T Expired - Lifetime ES2138784T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES90124241T Expired - Lifetime ES2095852T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.
ES94108611T Expired - Lifetime ES2101388T3 (es) 1990-12-14 1990-12-14 Antigenos sinteticos para la deteccion de anticuerpos para el virus de la hepatitis c.

Country Status (18)

Country Link
US (1) US5922532A (es)
EP (3) EP0644202B1 (es)
JP (1) JP2995216B2 (es)
KR (3) KR0181345B1 (es)
AT (3) ATE149522T1 (es)
AU (1) AU652013B2 (es)
BR (1) BR9106220A (es)
CY (2) CY2043A (es)
DE (2) DE69029092T2 (es)
DK (3) DK0489968T3 (es)
ES (3) ES2095852T3 (es)
GR (3) GR3022089T3 (es)
HK (1) HK57597A (es)
HU (1) HU218357B (es)
IL (1) IL100158A (es)
NZ (1) NZ240964A (es)
SG (1) SG47062A1 (es)
WO (1) WO1992010514A2 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US5683864A (en) * 1987-11-18 1997-11-04 Chiron Corporation Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
US6312889B1 (en) 1990-04-04 2001-11-06 Chiron Corporation Combinations of hepatitis c virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
ATE206717T1 (de) * 1990-11-03 2001-10-15 Dade Behring Marburg Gmbh Hcv-spezifische peptide, mittel dazu und ihre verwendung
US5910404A (en) * 1990-12-14 1999-06-08 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
AU1459792A (en) * 1991-01-14 1992-08-27 James N. Gamble Institute Of Medical Research Basic structural immunogenic polypeptides having epitopes for hcv, antibodies, polynucleotide sequences, vaccines and methods
RO117329B1 (ro) * 1991-06-24 2002-01-30 Chiron Corp Emeryville Polipeptide care contin o secventa a virusului hepatitei c
DE4209215A1 (de) * 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
US5811246A (en) * 1991-12-17 1998-09-22 The Research Foundation Of State University Of New York Process for immobilization onto the surfaces of ELISA plates of a compound carrier complex and for immunization
ZA928954B (en) * 1991-12-24 1993-05-19 Akzo Nv Peptides immunochemically reactive with antibodies directed against hepatitis non-A, non-B virus.
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
BR9305435A (pt) * 1992-03-06 1994-12-27 Innogenetics Nv Processo para determinação de peptídeos correspondendo a epítopos imunologicamente importantes e seu uso em um processo para determinação de anticorpos ou peptídeos biotinilados correspondendo a epítopos imunologicamente importantes, processo para preparação dos mesmos e composições contendo os mesmos
EP0586065B1 (en) * 1992-07-16 2010-03-24 Advanced Life Science Institute, Inc Antigenic peptides for grouping hepatitis C virus, kit comprising the same and methods for its grouping using the same
DE4240980A1 (de) * 1992-08-07 1994-02-10 Boehringer Mannheim Gmbh HCV Peptidantigene und Verfahren zur Bestimmung von HCV
ES2294779T3 (es) 1993-04-27 2008-04-01 N.V. Innogenetics S.A. Nuevas secuencias de genotipos del virus de la hepatitis c y su uso como agentes terapeuticos y de diagnostico.
IT1270941B (it) * 1993-05-12 1997-05-26 Sorin Biomedica Spa Peptidi di hcv e loro usi.
US7070790B1 (en) * 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
WO1996034013A1 (fr) * 1995-04-28 1996-10-31 Srl, Inc. Compose peptidique antigenique et methode de dosage immunologique
FR2775690B1 (fr) * 1998-03-09 2001-12-14 Bio Merieux Anticorps monoclonal et utilisations pour detecter des antigenes de la proteine core de vhc
AU3714499A (en) * 1998-05-14 1999-11-29 Pasteur Merieux Serums Et Vaccins Hepatitis c virus mimotopes
US7052830B1 (en) * 1998-06-09 2006-05-30 Branch Andrea D Hepatitis C virus peptides and uses thereof
ES2248357T3 (es) * 2000-07-07 2006-03-16 Medmira Inc. Composicion de antigeno mosaico de vhc.
AUPQ899400A0 (en) * 2000-07-26 2000-08-17 Csl Limited A method of stabilisation and compositions for use therein
JP4975601B2 (ja) * 2007-03-16 2012-07-11 シスメックス株式会社 Ｈｃｖ抗体測定用試薬キット及びｈｃｖ抗体測定方法
JP4975600B2 (ja) * 2007-03-16 2012-07-11 シスメックス株式会社 Ｈｃｖ抗体測定用試薬キット及びｈｃｖ抗体測定方法
US20080227111A1 (en) 2007-03-16 2008-09-18 Sysmex Corporation Reagent kit and method for measuring hcv antibody
ES2303496B1 (es) * 2008-02-21 2009-07-07 Fundacion Para El Estudio De Las Hepatitis Virales Metodo analitico perfeccionado para la deteccion de hepatitis c oculta, aplicaciones del mismo y su correspondiente kit de diagnostico.
US20100104555A1 (en) * 2008-10-24 2010-04-29 The Scripps Research Institute HCV neutralizing epitopes
FR2987836A1 (fr) * 2012-03-09 2013-09-13 Biomerieux Sa Peptides d'interference et procede de detection de microorganismes
CN114858907B (zh) * 2021-02-04 2025-02-18 北京毅新博创生物科技有限公司 用于诊断新冠病毒感染的质谱模型的构建方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US505611A (en) * 1893-09-26 Henry v
US594854A (en) * 1897-12-07 Territory
JP2702911B2 (ja) * 1985-09-11 1998-01-26 ユナイテツド・バイオメデイカル・インコ−ポレ−テツド 合成ペプチド、並びにそれを用いたエイズおよびプリ・エイズの検出方法
US4879212A (en) * 1986-04-02 1989-11-07 United Biomedical Inc. Peptide composition and method for the detection of antibodies to HTLV-III
US4749259A (en) * 1987-05-15 1988-06-07 Hughes Aircraft Company Liquid crystal image projection with multicolor prepolarizing system
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
DE318216T1 (de) * 1987-11-18 1990-06-13 Chiron Corp., Emeryville, Calif. Nanbv-diagnostika und vakzine.
UA50829C2 (uk) * 1989-03-17 2002-11-15 Чірон Корпорейшн Очищений поліпептид, що містить антиген вірусу гепатиту с, полінуклеотид, вектор, клітини, система експресії, моноклональне антитіло, препарат поліклональних антитіл, нуклеотидна проба, аналітичні набори, спосіб виявлення нуклеїнових кислот, способи імуноаналізу, вакцина, спосіб одержання антитіл
CA2032907C (en) * 1989-12-22 2002-05-14 Richard R. Lesniewski Hepatitis c assay
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
US5106726A (en) * 1990-02-16 1992-04-21 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV
EP0445801A3 (en) * 1990-03-08 1992-07-01 Kuraray Co., Ltd. Peptide and its use
ZA912040B (en) * 1990-03-30 1991-12-24 Akzo Nv Peptides immunochemically reactive with antibodies directed against hepatitis non-a,non-b virus
BR9106309A (pt) * 1990-04-04 1993-04-20 Chiron Corp Combinacao de antigenos sinteticos de hepatite c viral (hcv),processo de detectar anticorpos para o virus da hepatite c e estojo para realizar teste
AU660925B2 (en) * 1990-04-06 1995-07-13 Genelabs Technologies, Inc. Hepatitis C virus epitopes
AU635124B2 (en) * 1990-04-16 1993-03-11 United Biomedical Inc. Synthetic peptides specific for the detection of antibodies to HCV, diagnosis of HCV infection and prevention thereof as vaccines
WO1992001714A1 (en) * 1990-07-24 1992-02-06 Yamanouchi Pharmaceutical Co., Ltd. Non-a non-b hepatitis virus antigen
CA2047792C (en) * 1990-07-26 2002-07-02 Chang Y. Wang Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines
JP3114731B2 (ja) * 1990-08-14 2000-12-04 国立感染症研究所長 Ｃ型肝炎ウイルス抗体検出用ペプチド抗原及びその使用方法
KR930702365A (ko) * 1990-08-25 1993-09-08 존 더블유. 아담슨 비-a형, 비-b형 간염 바이러스 항원, 진단 방법 및 백신
JP2949822B2 (ja) * 1990-10-03 1999-09-20 住友化学工業株式会社 熱可塑性樹脂組成物
ATE206717T1 (de) * 1990-11-03 2001-10-15 Dade Behring Marburg Gmbh Hcv-spezifische peptide, mittel dazu und ihre verwendung
EP0485209A1 (en) * 1990-11-08 1992-05-13 Immuno Japan Inc. Non A, non B hepatitis virus related antigen, antibody detection systems, polynucleotides and polypeptides
WO1992009634A1 (en) * 1990-11-29 1992-06-11 Toray Industries, Incorporated Non-a non-b hepatitis virus antigen protein
ES2066547T3 (es) * 1991-03-01 1995-03-01 Akzo Nobel Nv Peptidos, inmunoquimicamente reactivos con anticuerpos dirigidos contra virus de hepatitis no-a, no-b.
FI923448L (fi) * 1991-08-02 1993-02-03 Akzo Nv Non-a, non-b-peptid
ZA927243B (en) * 1991-10-07 1994-01-26 Akzo Nv Non-A, Non-B peptides
BR9305435A (pt) * 1992-03-06 1994-12-27 Innogenetics Nv Processo para determinação de peptídeos correspondendo a epítopos imunologicamente importantes e seu uso em um processo para determinação de anticorpos ou peptídeos biotinilados correspondendo a epítopos imunologicamente importantes, processo para preparação dos mesmos e composições contendo os mesmos

Also Published As

Publication number Publication date
HUT65930A (en) 1994-07-28
WO1992010514A2 (en) 1992-06-25
JP2995216B2 (ja) 1999-12-27
ATE144993T1 (de) 1996-11-15
JPH05503722A (ja) 1993-06-17
IL100158A (en) 1998-02-22
US5922532A (en) 1999-07-13
DK0489968T3 (da) 1997-03-24
WO1992010514A3 (en) 1992-08-20
KR0181345B1 (ko) 1999-04-01
BR9106220A (pt) 1993-03-30
HK57597A (en) 1997-05-09
EP0644202B1 (en) 1997-03-05
CY2043A (en) 1998-02-20
KR920703632A (ko) 1992-12-18
GR3032150T3 (en) 2000-04-27
DK0754704T3 (da) 2000-04-03
AU652013B2 (en) 1994-08-11
KR0181344B1 (ko) 1999-04-01
AU9068991A (en) 1992-07-08
SG47062A1 (en) 1998-03-20
HU9202645D0 (en) 1993-01-28
GR3023664T3 (en) 1997-09-30
EP0754704A2 (en) 1997-01-22
HU218357B (hu) 2000-08-28
DK0644202T3 (da) 1997-09-15
EP0754704A3 (en) 1997-05-28
EP0489968A1 (en) 1992-06-17
DE69030124D1 (de) 1997-04-10
NZ240964A (en) 1992-10-28
EP0754704B1 (en) 1999-10-06
GR3022089T3 (en) 1997-03-31
EP0489968B1 (en) 1996-11-06
ES2101388T3 (es) 1997-07-01
KR0181343B1 (ko) 1999-04-01
EP0644202A1 (en) 1995-03-22
CY2053B1 (en) 1998-04-30
DE69029092T2 (de) 1997-04-17
DE69030124T2 (de) 1997-09-18
ATE185350T1 (de) 1999-10-15
ES2095852T3 (es) 1997-03-01
ATE149522T1 (de) 1997-03-15
DE69029092D1 (de) 1996-12-12

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