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EA201200954A1 - Способ получения полугидрата гидрохлорида (r)-8-хлор-1-метил-2,3,4,5-тетрагидро-1н-3-бензазепина, фармацевтическая композиция на его основе и его применение - Google Patents

Способ получения полугидрата гидрохлорида (r)-8-хлор-1-метил-2,3,4,5-тетрагидро-1н-3-бензазепина, фармацевтическая композиция на его основе и его применение

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Publication number
EA201200954A1
EA201200954A1 EA201200954A EA201200954A EA201200954A1 EA 201200954 A1 EA201200954 A1 EA 201200954A1 EA 201200954 A EA201200954 A EA 201200954A EA 201200954 A EA201200954 A EA 201200954A EA 201200954 A1 EA201200954 A1 EA 201200954A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methyl
chlor
hydrochloride
tetrahydro
benzazepina
Prior art date
Application number
EA201200954A
Other languages
English (en)
Inventor
Раджеш Кумар Агарвал
Уилльям Л. Ш. Беттс
Джеймс А. Хеншилвуд
Юан-Хон Кианг
Ноа Пост
Original Assignee
Арена Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36602366&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201200954(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Арена Фармасьютикалз, Инк. filed Critical Арена Фармасьютикалз, Инк.
Publication of EA201200954A1 publication Critical patent/EA201200954A1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract

Настоящее изобретение относится к способу получения полугидрата гидрохлорида (R)-8-хлор-1-метил-2,3,4,5-тетрагидро-1Н-3-бензазепина, содержащим его композициям, их получению и их применению, а также к способу лечения заболеваний, связанных с 5HT, лечения ожирения, снижения потребления пищи, индуцирования чувства сытости или контроля потребления пищи.
EA201200954A 2004-12-21 2005-12-20 Способ получения полугидрата гидрохлорида (r)-8-хлор-1-метил-2,3,4,5-тетрагидро-1н-3-бензазепина, фармацевтическая композиция на его основе и его применение EA201200954A1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63822104P 2004-12-21 2004-12-21

Publications (1)

Publication Number Publication Date
EA201200954A1 true EA201200954A1 (ru) 2013-05-30

Family

ID=36602366

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201200954A EA201200954A1 (ru) 2004-12-21 2005-12-20 Способ получения полугидрата гидрохлорида (r)-8-хлор-1-метил-2,3,4,5-тетрагидро-1н-3-бензазепина, фармацевтическая композиция на его основе и его применение
EA200701358A EA017894B1 (ru) 2004-12-21 2005-12-20 Кристаллические формы гидрохлорида (r)-8-хлор-1-метил-2,3,4,5-тетрагидро-1h-3-бензазепина

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA200701358A EA017894B1 (ru) 2004-12-21 2005-12-20 Кристаллические формы гидрохлорида (r)-8-хлор-1-метил-2,3,4,5-тетрагидро-1h-3-бензазепина

Country Status (28)

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US (4) US8168624B2 (ru)
EP (3) EP2149562A1 (ru)
JP (3) JP5270167B2 (ru)
KR (1) KR101281919B1 (ru)
CN (2) CN101084193B (ru)
AT (1) ATE442359T1 (ru)
AU (1) AU2005318959B2 (ru)
BR (1) BRPI0519726B8 (ru)
CA (1) CA2589988C (ru)
CU (1) CU20070138A7 (ru)
CY (1) CY1109599T1 (ru)
DE (1) DE602005016603D1 (ru)
DK (1) DK1838677T3 (ru)
EA (2) EA201200954A1 (ru)
ES (1) ES2332009T3 (ru)
HR (1) HRP20090640T1 (ru)
IL (1) IL183844A (ru)
MA (1) MA29147B1 (ru)
ME (1) ME01090B (ru)
NI (1) NI200700160A (ru)
NZ (2) NZ589756A (ru)
PL (1) PL1838677T3 (ru)
PT (1) PT1838677E (ru)
RS (1) RS50996B (ru)
SI (1) SI1838677T1 (ru)
TN (1) TNSN07235A1 (ru)
WO (1) WO2006069363A2 (ru)
ZA (1) ZA200705125B (ru)

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