DK3366295T3 - Fremgangsmåder til behandling af filoviridae virusinfektioner - Google Patents

Fremgangsmåder til behandling af filoviridae virusinfektioner Download PDF

Info

Publication number: DK3366295T3
Authority: DK; Denmark
Prior art keywords: philovirida; treating; methods; virus infections; infections
Prior art date: 2014-10-29

Application number

DK18167340.1T

Other languages

English (en)

Inventor

Byoung Kwon Chun

Michael O'neil Hanrahan Clarke

Edward Doerffler

Hon Chung Hui

Robert Jordan

Richard L Mackman

Jay P Parrish

Adrian S Ray

Dustin Siegel

Original Assignee

Gilead Sciences Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-10-29

Filing date

2015-10-29

Publication date

2020-04-06

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54557474&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3366295(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2015-10-29 Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc

2020-04-06 Application granted granted Critical

2020-04-06 Publication of DK3366295T3 publication Critical patent/DK3366295T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
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- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
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- C07F9/24—Esteramides
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- C07F9/2429—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of arylalkanols
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- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
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- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
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- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
- C—CHEMISTRY; METALLURGY
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- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
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- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
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- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
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- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
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- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/14—Pyrrolo-pyrimidine radicals
- C—CHEMISTRY; METALLURGY
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- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
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- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Plural Heterocyclic Compounds (AREA)

DK18167340.1T 2014-10-29 2015-10-29 Fremgangsmåder til behandling af filoviridae virusinfektioner DK3366295T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201462072331P	2014-10-29	2014-10-29
US201562105619P	2015-01-20	2015-01-20
EP15797205.0A EP3212174B1 (en)	2014-10-29	2015-10-29	Methods for treating filoviridae virus infections

Publications (1)

Publication Number	Publication Date
DK3366295T3 true DK3366295T3 (da)	2020-04-06

Family

ID=54557474

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK18167340.1T DK3366295T3 (da)	2014-10-29	2015-10-29	Fremgangsmåder til behandling af filoviridae virusinfektioner
DK15797205.0T DK3212174T3 (da)	2014-10-29	2015-10-29	Fremgangsmåder til behandling af filoviridae-virusinfektioner

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK15797205.0T DK3212174T3 (da)	2014-10-29	2015-10-29	Fremgangsmåder til behandling af filoviridae-virusinfektioner

Country Status (45)

Country	Link
US (8)	US9724360B2 (da)
EP (7)	EP4036099B1 (da)
JP (9)	JP6220484B1 (da)
KR (6)	KR101822348B1 (da)
CN (6)	CN113620992B (da)
AR (2)	AR102468A1 (da)
AU (8)	AU2015339222B2 (da)
BR (2)	BR102015027413A2 (da)
CA (3)	CA2963907C (da)
CL (2)	CL2017001040A1 (da)
CO (1)	CO2017003960A2 (da)
CR (2)	CR20170165A (da)
CU (2)	CU20170056A7 (da)
CY (2)	CY1120893T1 (da)
DK (2)	DK3366295T3 (da)
DO (1)	DOP2017000103A (da)
EA (2)	EA201790630A1 (da)
EC (2)	ECSP17025261A (da)
ES (5)	ES2785034T3 (da)
HR (1)	HRP20181130T1 (da)
HU (2)	HUE039231T2 (da)
IL (2)	IL251560A0 (da)
LT (2)	LT3212174T (da)
MA (3)	MA40872A (da)
MD (1)	MD20170046A2 (da)
ME (1)	ME03070B (da)
MX (3)	MX2017005252A (da)
MY (1)	MY195823A (da)
NZ (3)	NZ745328A (da)
PE (2)	PE20180202A1 (da)
PH (2)	PH12017500631B1 (da)
PL (5)	PL3695844T3 (da)
PT (4)	PT3212174T (da)
RS (1)	RS57425B1 (da)
SA (1)	SA517381419B1 (da)
SG (3)	SG10202008772UA (da)
SI (4)	SI3366295T1 (da)
SM (1)	SMT201800381T1 (da)
SV (2)	SV2017005424A (da)
TR (1)	TR201809518T4 (da)
TW (4)	TWI740546B (da)
UA (1)	UA121485C2 (da)
UY (2)	UY36376A (da)
WO (3)	WO2016069827A1 (da)
ZA (1)	ZA201800414B (da)

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WO2011035250A1 (en)	2009-09-21	2011-03-24	Gilead Sciences, Inc.	Processes and intermediates for the preparation of 1'-substituted carba-nucleoside analogs
JP5969471B2 (ja)	2010-07-22	2016-08-17	ギリード・サイエンシズ・インコーポレーテッド	パラミクソウイルス科ウイルス感染症を治療するための方法及び化合物
TWI740546B (zh) *	2014-10-29	2021-09-21	美商基利科學股份有限公司	製備核糖苷的方法
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EP3538108A4 (en) *	2016-11-10	2020-06-17	Oyagen, Inc.	METHODS OF TREATING AND INHIBITING EBOLA VIRUS INFECTION
WO2018091633A1 (en) *	2016-11-18	2018-05-24	Neurovive Pharmaceutical Ab	Liver prodrugs of mitochondrial proton ionophores
KR102460968B1 (ko)	2017-03-14	2022-11-01	길리애드 사이언시즈, 인코포레이티드	고양이 코로나바이러스 감염의 치료 방법
JP6923112B2 (ja) *	2017-03-31	2021-08-18	国立大学法人北海道大学	フィロウイルスの細胞侵入阻害活性を有するビアリールスルフォンアミド誘導体
CN110636884B (zh)	2017-05-01	2022-10-04	吉利德科学公司	新结晶形式
TW201919648A (zh) *	2017-07-11	2019-06-01	美商基利科學股份有限公司	用於治療病毒感染之含rna聚合酶抑制劑與環糊精的組合物
CN111542531B (zh) *	2017-09-18	2024-07-19	詹森生物制药有限公司	取代的核苷、核苷酸以及它们的类似物
CN109535200A (zh) *	2017-09-21	2019-03-29	杭州和正医药有限公司	一种核苷类似物的磷酰胺酯前药、药物组合物及其应用
CN109748944B (zh) *	2017-11-03	2021-12-10	中国科学院上海药物研究所	5’-脱氧-5’-异丙基取代氨基核苷类化合物、其制备方法和用途
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US10695357B2 (en)	2020-06-30
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CA2963907C (en)	2023-04-04
UY37464A (es)	2019-04-30

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