[go: up one dir, main page]

DK258590A - Forbedrede emulsioner af staerkt fluorerede organiske forbindelser - Google Patents

Forbedrede emulsioner af staerkt fluorerede organiske forbindelser Download PDF

Info

Publication number
DK258590A
DK258590A DK258590A DK258590A DK258590A DK 258590 A DK258590 A DK 258590A DK 258590 A DK258590 A DK 258590A DK 258590 A DK258590 A DK 258590A DK 258590 A DK258590 A DK 258590A
Authority
DK
Denmark
Prior art keywords
organic compounds
highly
fluored
emulsions
improved emulsions
Prior art date
Application number
DK258590A
Other languages
English (en)
Other versions
DK172973B1 (da
DK258590D0 (da
Inventor
Robert J Kaufman
Thomas J Richard
Original Assignee
Hemagen Pfc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hemagen Pfc filed Critical Hemagen Pfc
Publication of DK258590D0 publication Critical patent/DK258590D0/da
Publication of DK258590A publication Critical patent/DK258590A/da
Application granted granted Critical
Publication of DK172973B1 publication Critical patent/DK172973B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Colloid Chemistry (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK199002585A 1988-04-29 1990-10-26 Forbedrede emulsioner af stærkt fluorerede organiske forbindelser DK172973B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/187,854 US5171755A (en) 1988-04-29 1988-04-29 Emulsions of highly fluorinated organic compounds
US18785488 1988-04-29
US8901388 1989-04-10
PCT/US1989/001388 WO1989010118A1 (en) 1988-04-29 1989-04-10 Improved emulsions of highly fluorinated organic compounds

Publications (3)

Publication Number Publication Date
DK258590D0 DK258590D0 (da) 1990-10-26
DK258590A true DK258590A (da) 1990-10-29
DK172973B1 DK172973B1 (da) 1999-10-25

Family

ID=22690763

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199002585A DK172973B1 (da) 1988-04-29 1990-10-26 Forbedrede emulsioner af stærkt fluorerede organiske forbindelser

Country Status (16)

Country Link
US (3) US5171755A (da)
EP (1) EP0449825B1 (da)
JP (1) JPH0798745B2 (da)
KR (1) KR940002658B1 (da)
CN (1) CN1042794C (da)
AT (1) ATE112958T1 (da)
AU (1) AU629832B2 (da)
CA (1) CA1336494C (da)
DE (1) DE68918952T2 (da)
DK (1) DK172973B1 (da)
IE (1) IE65288B1 (da)
IL (1) IL90009A0 (da)
NZ (1) NZ228686A (da)
OA (1) OA09322A (da)
WO (1) WO1989010118A1 (da)
ZA (1) ZA892924B (da)

Families Citing this family (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5514720A (en) * 1986-07-09 1996-05-07 Hemagen/Pfc Stable emulsions of highly fluorinated organic compounds
US5684050A (en) * 1986-01-24 1997-11-04 Hemagen/Pfc Stable emulsions of highly fluorinated organic compounds
WO1991000110A1 (en) * 1989-07-05 1991-01-10 Alliance Pharmaceutical Corp. Fluorocarbon emulsions having saturated phospholipid emulsifiers
US5352435A (en) * 1989-12-22 1994-10-04 Unger Evan C Ionophore containing liposomes for ultrasound imaging
US5585112A (en) 1989-12-22 1996-12-17 Imarx Pharmaceutical Corp. Method of preparing gas and gaseous precursor-filled microspheres
US5773024A (en) * 1989-12-22 1998-06-30 Imarx Pharmaceutical Corp. Container with multi-phase composition for use in diagnostic and therapeutic applications
US6001335A (en) 1989-12-22 1999-12-14 Imarx Pharmaceutical Corp. Contrasting agents for ultrasonic imaging and methods for preparing the same
US5733572A (en) * 1989-12-22 1998-03-31 Imarx Pharmaceutical Corp. Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
US5776429A (en) 1989-12-22 1998-07-07 Imarx Pharmaceutical Corp. Method of preparing gas-filled microspheres using a lyophilized lipids
US6088613A (en) 1989-12-22 2000-07-11 Imarx Pharmaceutical Corp. Method of magnetic resonance focused surgical and therapeutic ultrasound
US5542935A (en) 1989-12-22 1996-08-06 Imarx Pharmaceutical Corp. Therapeutic delivery systems related applications
US5705187A (en) * 1989-12-22 1998-01-06 Imarx Pharmaceutical Corp. Compositions of lipids and stabilizing materials
US5922304A (en) 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
US20020150539A1 (en) 1989-12-22 2002-10-17 Unger Evan C. Ultrasound imaging and treatment
US5656211A (en) * 1989-12-22 1997-08-12 Imarx Pharmaceutical Corp. Apparatus and method for making gas-filled vesicles of optimal size
US6146657A (en) 1989-12-22 2000-11-14 Imarx Pharmaceutical Corp. Gas-filled lipid spheres for use in diagnostic and therapeutic applications
US6551576B1 (en) 1989-12-22 2003-04-22 Bristol-Myers Squibb Medical Imaging, Inc. Container with multi-phase composition for use in diagnostic and therapeutic applications
US5469854A (en) * 1989-12-22 1995-11-28 Imarx Pharmaceutical Corp. Methods of preparing gas-filled liposomes
US5305757A (en) * 1989-12-22 1994-04-26 Unger Evan C Gas filled liposomes and their use as ultrasonic contrast agents
US5580575A (en) * 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
USRE39146E1 (en) 1990-04-02 2006-06-27 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
IN172208B (da) * 1990-04-02 1993-05-01 Sint Sa
US6274148B1 (en) * 1990-11-08 2001-08-14 Chiron Corporation Hepatitis C virus asialoglycoproteins
US5874062A (en) * 1991-04-05 1999-02-23 Imarx Pharmaceutical Corp. Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents
US5205290A (en) 1991-04-05 1993-04-27 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
FR2679150A1 (fr) * 1991-07-17 1993-01-22 Atta Preparations comprenant un fluorocarbure ou compose hautement fluore et un compose organique lipophile-fluorophile, et leurs utilisations.
MX9205298A (es) 1991-09-17 1993-05-01 Steven Carl Quay Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
US6723303B1 (en) 1991-09-17 2004-04-20 Amersham Health, As Ultrasound contrast agents including protein stabilized microspheres of perfluoropropane, perfluorobutane or perfluoropentane
US5409688A (en) * 1991-09-17 1995-04-25 Sonus Pharmaceuticals, Inc. Gaseous ultrasound contrast media
US6875420B1 (en) 1991-09-17 2005-04-05 Amersham Health As Method of ultrasound imaging
EP0605477B2 (en) * 1991-09-17 2007-06-20 GE Healthcare AS Gaseous ultrasound contrast media
US5304325A (en) * 1991-11-13 1994-04-19 Hemagen/Pfc Emulsions containing alkyl- or alkylglycerophosphoryl choline surfactants and methods of use
US5403575A (en) * 1991-12-12 1995-04-04 Hemagen/Pfc Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of using them
US5295953A (en) * 1992-05-26 1994-03-22 Hemagen/Pfc Method and apparatus for extracorporeal separation of fluorochemicals from whole blood of a patient
US5628930A (en) * 1992-10-27 1997-05-13 Alliance Pharmaceutical Corp. Stabilization of fluorocarbon emulsions
US5420359A (en) * 1992-12-11 1995-05-30 Minnesota Mining And Manufacturing Company Chlorofluoroether compositions and preparation thereof
AU5539294A (en) * 1992-12-24 1994-07-19 Hemagen/Pfc Fluorocarbon emulsions
US5558855A (en) * 1993-01-25 1996-09-24 Sonus Pharmaceuticals Phase shift colloids as ultrasound contrast agents
IL108416A (en) 1993-01-25 1998-10-30 Sonus Pharma Inc Colloids with phase difference as contrast ultrasound agents
DE69427185T2 (de) * 1993-01-25 2001-12-06 Sonus Pharmaceutical, Inc. Phase-Stift Kolloide zur Verwendung als Ultraschallkontrastmittel
US5650156A (en) * 1993-02-22 1997-07-22 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of nutriceuticals and compositions useful therefor
US20030068362A1 (en) * 1993-02-22 2003-04-10 American Bioscience, Inc. Methods and formulations for the delivery of pharmacologically active agents
US5362478A (en) * 1993-03-26 1994-11-08 Vivorx Pharmaceuticals, Inc. Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell
US6753006B1 (en) 1993-02-22 2004-06-22 American Bioscience, Inc. Paclitaxel-containing formulations
US5665382A (en) * 1993-02-22 1997-09-09 Vivorx Pharmaceuticals, Inc. Methods for the preparation of pharmaceutically active agents for in vivo delivery
US20030133955A1 (en) * 1993-02-22 2003-07-17 American Bioscience, Inc. Methods and compositions useful for administration of chemotherapeutic agents
US5525324A (en) * 1993-08-06 1996-06-11 Block; Ronald E. Organic silicon contrast agents and methods of use
US7083572B2 (en) 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
DE69432295T2 (de) 1993-12-15 2003-08-14 Bracco Research Sa Gas-mischungen verwendbar als ultraschallkontrastmittel
US5658962A (en) 1994-05-20 1997-08-19 Minnesota Mining And Manufacturing Company Omega-hydrofluoroalkyl ethers, precursor carboxylic acids and derivatives thereof, and their preparation and application
US5502094A (en) * 1994-05-20 1996-03-26 Minnesota Mining And Manufacturing Company Physiologically acceptable emulsions containing perfluorocarbon ether hydrides and methods for use
US5736121A (en) * 1994-05-23 1998-04-07 Imarx Pharmaceutical Corp. Stabilized homogenous suspensions as computed tomography contrast agents
CA2152765A1 (en) 1994-06-30 1995-12-31 Jeroen Elisabeth-Joseph Knops Methods for treating a physiological disorder associated with beta amyloid peptide
US6743779B1 (en) 1994-11-29 2004-06-01 Imarx Pharmaceutical Corp. Methods for delivering compounds into a cell
US5830430A (en) 1995-02-21 1998-11-03 Imarx Pharmaceutical Corp. Cationic lipids and the use thereof
US5997898A (en) 1995-06-06 1999-12-07 Imarx Pharmaceutical Corp. Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery
US6231834B1 (en) 1995-06-07 2001-05-15 Imarx Pharmaceutical Corp. Methods for ultrasound imaging involving the use of a contrast agent and multiple images and processing of same
US6521211B1 (en) 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
US6139819A (en) 1995-06-07 2000-10-31 Imarx Pharmaceutical Corp. Targeted contrast agents for diagnostic and therapeutic use
US6033645A (en) 1996-06-19 2000-03-07 Unger; Evan C. Methods for diagnostic imaging by regulating the administration rate of a contrast agent
US5804162A (en) * 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
DE19529921C2 (de) * 1995-08-01 1997-09-25 Schering Ag Verwendung von MRT-Kontrastmitteln zur Ventilations-Bildgebung der Lunge
WO1997015306A1 (en) * 1995-10-25 1997-05-01 Janssen Pharmaceutica N.V. Infusions of neuroprotectants and perfluorochemicals
US5733526A (en) * 1995-12-14 1998-03-31 Alliance Pharmaceutical Corp. Hydrocarbon oil/fluorochemical preparations and methods of use
WO1997025978A1 (fr) * 1996-01-15 1997-07-24 BELOYARTSEV, Arkady Felixovich Procede de production d'emulsions perfluorocarbonees a des fins medicales
US5611344A (en) * 1996-03-05 1997-03-18 Acusphere, Inc. Microencapsulated fluorinated gases for use as imaging agents
JP3178724B2 (ja) * 1996-03-05 2001-06-25 エイカスフィアー・インコーポレーテッド 画像化剤として使用するためのミクロカプセル化フッ素化ガス
ATE345682T1 (de) 1996-05-01 2006-12-15 Imarx Pharmaceutical Corp In vitro verfahren zum einbringen von nukleinsäuren in eine zelle
US5837221A (en) * 1996-07-29 1998-11-17 Acusphere, Inc. Polymer-lipid microencapsulated gases for use as imaging agents
US6414139B1 (en) 1996-09-03 2002-07-02 Imarx Therapeutics, Inc. Silicon amphiphilic compounds and the use thereof
DK0977597T3 (da) 1996-09-11 2003-05-05 Imarx Pharmaceutical Corp Forbedrede fremgangsmåder til diagnostisk billeddannelse ved hjælp af et kontrastmiddel og en vasodilatator.
US5846517A (en) 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
US8137684B2 (en) 1996-10-01 2012-03-20 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
AU5161298A (en) * 1996-11-25 1998-06-22 Imarx Pharmaceutical Corp. Perfluorinated-ether compositions as diagnostic contrast agents
DE19701037A1 (de) * 1997-01-15 1998-07-16 Sanguibiotech Ag Mit Schutzliganden der Sauerstoffbindungsstellen versehene Hämoglobine als künstliche Sauerstoffträger zur direkten biologisch-medizinischen Anwendung und Verfahren zu ihrer Herstellung
US6143276A (en) 1997-03-21 2000-11-07 Imarx Pharmaceutical Corp. Methods for delivering bioactive agents to regions of elevated temperatures
US6537246B1 (en) * 1997-06-18 2003-03-25 Imarx Therapeutics, Inc. Oxygen delivery agents and uses for the same
US6120751A (en) 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same
US6090800A (en) 1997-05-06 2000-07-18 Imarx Pharmaceutical Corp. Lipid soluble steroid prodrugs
US7452551B1 (en) 2000-10-30 2008-11-18 Imarx Therapeutics, Inc. Targeted compositions for diagnostic and therapeutic use
US6416740B1 (en) 1997-05-13 2002-07-09 Bristol-Myers Squibb Medical Imaging, Inc. Acoustically active drug delivery systems
US20020039594A1 (en) * 1997-05-13 2002-04-04 Evan C. Unger Solid porous matrices and methods of making and using the same
JPH113349A (ja) * 1997-06-11 1999-01-06 Fujitsu Ltd データ保護システム，データ作成装置及びデータ加工装置
US5980936A (en) * 1997-08-07 1999-11-09 Alliance Pharmaceutical Corp. Multiple emulsions comprising a hydrophobic continuous phase
US6548047B1 (en) 1997-09-15 2003-04-15 Bristol-Myers Squibb Medical Imaging, Inc. Thermal preactivation of gaseous precursor filled compositions
US6123923A (en) 1997-12-18 2000-09-26 Imarx Pharmaceutical Corp. Optoacoustic contrast agents and methods for their use
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
US7220401B2 (en) * 1999-09-24 2007-05-22 Barnes-Jewish Hospital Blood clot-targeted nanoparticles
EP1118312A3 (en) 2000-01-18 2003-04-02 Implant Innovations, Inc. Preparation coping for creating an accurate permanent post to support a final prosthesis and method for creating the same
KR100372555B1 (ko) * 2000-04-20 2003-02-17 주식회사 도도화장품 산소를 용해시킨 과플루오로데칼린과 대두에서 추출한유용성분을 함유하는 미백용 화장품의 제조방법
US6676963B1 (en) 2000-10-27 2004-01-13 Barnes-Jewish Hospital Ligand-targeted emulsions carrying bioactive agents
CN100356984C (zh) 2002-01-24 2007-12-26 巴内斯－朱威胥医院 整联蛋白靶向的影像剂
EP1365068B1 (en) * 2002-05-10 2008-05-07 The Procter & Gamble Company Embossed tissue having loosened surface fibers and method for its production
RU2259819C1 (ru) * 2004-03-01 2005-09-10 Кузнецова Ирина Николаевна Эмульсия перфторорганических соединений медицинского назначения и способ её получения
US8012457B2 (en) 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
WO2005122891A1 (en) 2004-06-09 2005-12-29 Kereos, Inc. Lipophilic derivatives of chelate monoamides
WO2007127958A2 (en) * 2006-04-27 2007-11-08 Barnes-Jewish Hospital Detection and imaging of target tissue
DE602007003135D1 (de) 2006-05-18 2009-12-24 Mitsubishi Gas Chemical Co Verfahren zur Herstellung von Xylylenediamin
DE102006040450B3 (de) * 2006-08-24 2008-04-24 Coty Prestige Lancaster Group Gmbh Verwendung einer Zusammensetzung für die Hautbehandlung nach Röntgenbestrahlung
WO2009049089A1 (en) 2007-10-09 2009-04-16 Washington University In St. Louis Ligand directed toroidal nanoparticles for therapy and diagnostic imaging
EP2209420A4 (en) 2007-10-09 2014-01-22 Univ St Louis PARTICULARS FOR IMAGING
US9764043B2 (en) 2009-12-17 2017-09-19 Washington University Antithrombotic nanoparticle
US9808500B2 (en) 2009-12-17 2017-11-07 Washington University Antithrombotic nanoparticle
WO2011130674A1 (en) 2010-04-15 2011-10-20 The Washington University Prodrug compositions, prodrug nanoparticles, and methods of use thereof
FR2980364B1 (fr) 2011-09-26 2018-08-31 Guerbet Nanoemulsions et leur utilisation comme agents de contraste
FR2980365B1 (fr) 2011-09-26 2016-02-12 Guerbet Sa Nanoemulsions, leur procede de preparation, et leur utilisation comme agent de contraste.
WO2013116691A1 (en) 2012-02-02 2013-08-08 The Washington University Methods for improving muscle strength
EP2783703A1 (en) * 2013-03-25 2014-10-01 B. Braun Melsungen AG Semifluorocarbon compound containing contrast agent
RU2544849C1 (ru) * 2014-01-09 2015-03-20 Общество с ограниченной ответственностью "Химический завод фторсолей" Способ очистки перфтордекалина
EP3240579B1 (en) 2014-12-31 2022-07-27 Lantheus Medical Imaging, Inc. Lipid-encapsulated gas microsphere compositions and related methods
CN105248412A (zh) * 2015-10-30 2016-01-20 暨南大学 一种乳化氟碳液在制备肺器官保存液中的应用
US10213448B2 (en) 2016-03-25 2019-02-26 Novazoi Theranostics Ethanolamine-based lipid biosynthetic compounds, method of making and use thereof
CN115531560B (zh) 2016-05-04 2024-05-17 蓝瑟斯医学影像公司 用于制备超声波造影剂的方法及装置
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents
CN108849861A (zh) * 2018-09-30 2018-11-23 南京麦荻泉生物科技有限公司 一种含有氟碳乳剂型器官保存液
WO2024046999A1 (de) * 2022-08-31 2024-03-07 Johann Wolfgang Goethe-Universität Frankfurt am Main Lecithin-modifizierte nanoskalierte sauerstoffträger (lenox)

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2055083A (en) * 1932-07-13 1936-09-22 Winthrop Chem Co Inc Pharmaceutical preparation
GB1256162A (en) * 1968-08-16 1971-12-08 Braun Fa B Improvements in and relating to liquid products for intravenous administration
US3958014A (en) * 1970-09-05 1976-05-18 The Green Cross Corporation Process for preparing injection-purpose fluorocarbon emulsion capable of carrying oxygen
US3975512A (en) * 1970-12-21 1976-08-17 University Of Illinois Foundation Non-toxic brominated perfluorocarbons radiopaque agents
US3823091A (en) * 1971-05-19 1974-07-09 Green Cross Corp Stable emulsion of fluorocarbon particles
US3942527A (en) * 1972-03-14 1976-03-09 Exxon Research & Engineering Co. Blood oxygenation process
US3778381A (en) * 1972-04-24 1973-12-11 Allied Chem Fluorocarbon microemulsions
US3914294A (en) * 1972-06-01 1975-10-21 Squibb & Sons Inc 3,5-Disubstituted-2,4,6-triiodobenzoic acids
US3911138B1 (en) * 1973-02-26 1996-10-29 Childrens Hosp Medical Center Artificial blood and method for supporting oxygen transport in animals
JPS5331209B2 (da) * 1973-10-05 1978-09-01
US3993581A (en) * 1973-10-05 1976-11-23 The Green Cross Corporation Process for preparing stable oxygen transferable emulsion
FR2249657B1 (da) * 1973-11-07 1977-04-15 Ugine Kuhlmann
JPS5126213A (ja) * 1974-08-21 1976-03-04 Tanabe Seiyaku Co Johoseibiryushiseizaino seiho
US4073879A (en) * 1974-08-26 1978-02-14 University Of Illinois Foundation Brominated perfluorocarbon radiopaque agents
US4073943A (en) * 1974-09-11 1978-02-14 Apoteksvarucentralen Vitrum Ab Method of enhancing the administration of pharmalogically active agents
US4105798A (en) * 1976-07-19 1978-08-08 Sun Ventures, Inc. Perfluoro polycyclic compounds for use as synthetic blood and perfusion media
US4110474A (en) * 1977-08-26 1978-08-29 Suntech, Inc. Tetramethylpentane blood substitutes
US4186253A (en) * 1978-10-10 1980-01-29 The Green Cross Corporation Perfusate for preserving organ to be transplanted and preserving method
JPS55100312A (en) * 1979-01-25 1980-07-31 Toshiro Wada Contrast medium for blood vessel
US4252827A (en) * 1979-05-23 1981-02-24 The Green Cross Corporation Oxygen-transferable fluorocarbon emulsion
DE3049665T1 (de) * 1979-06-25 1982-03-18 Suntech Use of perfluorocarbon as burn treatment
US4657532A (en) * 1985-07-19 1987-04-14 Thomas Jefferson University Intra-peritoneal perfusion of oxygenated fluorocarbon
CA1181011A (en) * 1980-05-27 1985-01-15 Robert P. Geyer Perfluorinated n,n-dimethyl cyclohexylmethylamine and emulsions containing the same
FR2515198A1 (fr) * 1981-10-22 1983-04-29 Centre Nat Rech Scient Microemulsions aqueuses de fluorocarbures indefiniment stables a une temperature donnee, procede d'obtention et application a titre de transporteurs d'oxygene
US4569784A (en) * 1980-11-17 1986-02-11 Adamantech, Inc. Preparation of a gel having gas transporting capability
JPS5924132B2 (ja) * 1980-12-02 1984-06-07 株式会社 林原生物化学研究所 栄養補給用乳剤の製法
JPS57188514A (en) * 1981-05-12 1982-11-19 Green Cross Corp:The Fluorine compound emulsion
US4395393A (en) * 1981-08-10 1983-07-26 Basf Wyandotte Corporation Artificial blood emulsifiers
JPS5832829A (ja) * 1981-08-22 1983-02-25 Green Cross Corp:The 血管造影剤
JPS5892680A (ja) * 1981-11-27 1983-06-02 Green Cross Corp:The パ−フルオロビシクロ化合物
US4591599A (en) * 1981-11-27 1986-05-27 The Green Cross Corporation Perfluoropyrrolizines and emulsions thereof useful as blood substitutes
US4599343A (en) * 1981-11-27 1986-07-08 The Green Cross Corporation Perfluoroindolizines and emulsions thereof useful as blood substitutes
CA1187882A (en) * 1981-11-27 1985-05-28 Kazumasa Yokoyama Perfluoro compound and emulsion thereof
JPS58170782A (ja) * 1982-01-22 1983-10-07 アイ・エス・シ−・ケミカルズ・リミテツド 過弗素化複素環式化合物およびこれを含むエマルシヨン
US4446154A (en) * 1982-03-03 1984-05-01 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4490351A (en) * 1982-03-15 1984-12-25 Children's Hospital Medical Center Methods of treating disorders of an eye with liquid perfluorocarbons
US4461717A (en) * 1982-03-19 1984-07-24 Sun Tech, Inc. Stable gas-carrying compositions
US4452818A (en) * 1982-03-19 1984-06-05 Haidt Sterling J Extraocular method of treating the eye with liquid perfluorocarbons
US4443480A (en) * 1982-04-12 1984-04-17 Children's Hospital Medical Center Artificial blood and other gas transport agents
US4423077A (en) * 1982-07-27 1983-12-27 The University Of Pennsylvania Perfluorochemical emulsion artificial blood
US4497829A (en) * 1982-07-27 1985-02-05 The University Of Pennsylvania Process for preparing perfluorochemical emulsion artificial blood
US4397870A (en) * 1982-07-27 1983-08-09 The University Of Pennsylvania Process for prolonging retention of emulsion particles in the bloodstream
DE3366683D1 (de) * 1982-08-07 1986-11-13 Green Cross Corp Perfluoro-1-azatricyclic amine compound
JPS5939870A (ja) * 1982-08-30 1984-03-05 Green Cross Corp:The フルオロカ−ボン乳化製剤
JPS5946218A (ja) * 1982-09-09 1984-03-15 Green Cross Corp:The フルオロカ−ボン乳化製剤
US4534978A (en) * 1982-12-28 1985-08-13 The Green Cross Corporation Perfluorocycloamines
JPS59130812A (ja) * 1983-01-14 1984-07-27 Green Cross Corp:The 癌化学療法補助剤
JPS59130813A (ja) * 1983-01-14 1984-07-27 Green Cross Corp:The 癌化学療法補助剤
WO1984003624A1 (en) * 1983-03-17 1984-09-27 University Patents Inc Method for inhibiting the growth of anaerobes
JPS59193814A (ja) * 1983-04-20 1984-11-02 Ajinomoto Co Inc アミノ酸含有脂肪乳剤
US4519576A (en) * 1983-12-15 1985-05-28 Winegeart Mitchell E Oil well safety valve for use with drill pipe
CA1257828A (en) * 1984-04-16 1989-07-25 William Mccormick Perfluoro compound dispersions containing reduced amounts of surfactant and process of preparation
CA1257131A (en) * 1984-07-27 1989-07-11 John Y. Park Total parenteral and enteral nutrition composition
IT1186704B (it) * 1985-04-04 1987-12-16 Motefluos Spa Perfluorcalcani e aloperfluoroalcani,loro precursori e loro processo di sintesi
SE8505047L (sv) * 1985-10-25 1987-04-26 Nutritional Int Res Inst Fettemulsion
SE8505048L (sv) * 1985-10-25 1987-04-26 Nutritional Int Res Inst Nutritionsemulsion med syretransporterande egenskaper
US5080885A (en) * 1986-01-14 1992-01-14 Alliance Pharmaceutical Corp. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
US4865836A (en) * 1986-01-14 1989-09-12 Fluoromed Pharmaceutical, Inc. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
ES2054658T3 (es) * 1986-01-24 1994-08-16 Childrens Hosp Medical Center Metodo para la preparacion de una emulsion fisiologicamente aceptable.
US4866096A (en) * 1987-03-20 1989-09-12 Air Products And Chemicals, Inc. Stable fluorochemical aqueous emulsions
US4895876A (en) * 1987-03-20 1990-01-23 Air Products And Chemicals, Inc. Concentrated stable fluorochemical aqueous emulsions containing triglycerides

Also Published As

Publication number Publication date
EP0449825B1 (en) 1994-10-19
DE68918952T2 (de) 1995-03-16
DK172973B1 (da) 1999-10-25
ATE112958T1 (de) 1994-11-15
KR900700085A (ko) 1990-08-11
KR940002658B1 (ko) 1994-03-28
CA1336494C (en) 1995-08-01
EP0449825A1 (en) 1991-10-09
AU629832B2 (en) 1992-10-15
AU3566489A (en) 1989-11-24
WO1989010118A1 (en) 1989-11-02
US5350571A (en) 1994-09-27
JPH03502693A (ja) 1991-06-20
US5171755A (en) 1992-12-15
IE65288B1 (en) 1995-10-18
JPH0798745B2 (ja) 1995-10-25
OA09322A (en) 1992-09-15
NZ228686A (en) 1994-09-27
IE891396L (en) 1989-10-29
CN1042794C (zh) 1999-04-07
IL90009A0 (en) 1989-12-15
ZA892924B (en) 1989-12-27
DK258590D0 (da) 1990-10-26
CN1038022A (zh) 1989-12-20
DE68918952D1 (de) 1994-11-24
US5407962A (en) 1995-04-18

Similar Documents

Publication Publication Date Title
DK258590D0 (da) Forbedrede emulsioner af staerkt fluorerede organiske forbindelser
NO160249C (no) Offshoreplattform.
DE3579810D1 (de) Epidermalisierung der oberflaeche eines kuenstlichen dermas.
FI834552A (fi) Tvaettmedel i pulverform och som goer textilerna mjuka.
NO851916L (no) Anordning for aa sperre en offshore-plattform i forhold til ben som baerer plattformen.
FI843392A (fi) (substituerade)fenyl-alifatiska isoxazoler anvaendbara som antivirala aemnen och deras framstaellning.
NL7900756A (nl) Heterostructuur laser.
OA06984A (fr) Plate-forme offshore.
FI852310A0 (fi) Anordning och foerfarande foer permeabilitetsmaetning.
IT7921833A0 (it) Epossidazione di alfa-olefine inferiori.
JPS52154528A (en) Remedy for glaucoma
SE8104538L (sv) 1-klor-1-p-metoxibensoylformaldoxim-n-metylkarbamat
JPS5269908A (en) Water-in-oil emulsion fuel
JPS534007A (en) Fuel composition
FI896048A0 (fi) 5-fluormetyl-1,2,4-triazolo/1,5-a/ pyrimidin-2-sulfonamider, foerfaranden foer deras framstaellning och kompositioner foer deras anvaendning som herbicider.
JPS5350080A (en) Finishing agent composition with excellent stainproofing power
JPS537671A (en) 3-phenylhydantoin derivatives, their preparation and nonmedical fungicides containing the same
JPS532468A (en) 2,2-bis(3,4-epoxy-5-oxotetrahydropyrane)-ethers and method of preparing the same
JPS52106844A (en) 3-cyanomethylcyclopentanone derivatives
JPS5391684A (en) Semiconductor laser
DE69106452D1 (de) Fluorsubstituierte Etherverbindungen.
JPS5391682A (en) Semiconductor laser
JPS527882A (en) Water repellent, oil repellent agents
JPS5340770A (en) Preparation of 3-amino-1,3-thiazolidine-2,4-dions and repellent against water organisms containing the same
SU687445A1 (ru) Стабилизированный выпр митель

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

Country of ref document: DK