DK2074123T3 - Nye anxiolytiske forbindelser - Google Patents
Nye anxiolytiske forbindelserInfo
- Publication number
- DK2074123T3 DK2074123T3 DK07815371.5T DK07815371T DK2074123T3 DK 2074123 T3 DK2074123 T3 DK 2074123T3 DK 07815371 T DK07815371 T DK 07815371T DK 2074123 T3 DK2074123 T3 DK 2074123T3
- Authority
- DK
- Denmark
- Prior art keywords
- anxiolytic compounds
- new anxiolytic
- new
- compounds
- anxiolytic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85198306P | 2006-10-16 | 2006-10-16 | |
PCT/AU2007/001566 WO2008046135A1 (en) | 2006-10-16 | 2007-10-16 | Novel anxiolytic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2074123T3 true DK2074123T3 (da) | 2013-01-14 |
Family
ID=39313499
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK07815371.5T DK2074123T3 (da) | 2006-10-16 | 2007-10-16 | Nye anxiolytiske forbindelser |
Country Status (13)
Country | Link |
---|---|
US (7) | US8293737B2 (da) |
EP (2) | EP2540722B1 (da) |
JP (4) | JP5373613B2 (da) |
AU (1) | AU2007312936B2 (da) |
CA (2) | CA2954376C (da) |
DK (1) | DK2074123T3 (da) |
ES (1) | ES2399071T3 (da) |
HK (1) | HK1132268A1 (da) |
NZ (1) | NZ576036A (da) |
PL (1) | PL2074123T3 (da) |
PT (1) | PT2074123E (da) |
SI (1) | SI2074123T1 (da) |
WO (1) | WO2008046135A1 (da) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2074123E (pt) | 2006-10-16 | 2013-01-22 | Bionomics Ltd | Novos compostos ansiolíticos |
US10954231B2 (en) | 2006-10-16 | 2021-03-23 | Bionomics Limited | Anxiolytic compounds |
WO2011031745A1 (en) | 2009-09-09 | 2011-03-17 | Achaogen, Inc. | Antibacterial fluoroquinolone analogs |
CA2828780A1 (en) | 2011-03-02 | 2012-09-07 | Bionomics Limited | Novel small-molecules as therapeutics |
US20140051701A1 (en) * | 2011-03-02 | 2014-02-20 | Bionomics Limited | Methods of treating a disease or condition of the central nervous system |
AU2012253237B2 (en) * | 2011-05-12 | 2015-09-24 | Bionomics Limited | Methods for preparing naphthyridines |
WO2014036595A1 (en) * | 2012-09-04 | 2014-03-13 | Bionomics Limited | Compounds and methods for treating diseases or conditions associated with the central nervous system and/or neurite outgrowth |
AU2013204159B2 (en) * | 2013-03-15 | 2015-05-07 | Bionomics Limited | A Crystalline Form of an Anxiolytic Compound |
JP2016510768A (ja) * | 2013-03-15 | 2016-04-11 | バイオノミックス リミテッド | 抗不安化合物の塩、共結晶及び多形 |
WO2019109150A1 (en) * | 2017-12-07 | 2019-06-13 | Bionomics Limited | Methods of treating agitation |
US20210355124A1 (en) * | 2018-10-18 | 2021-11-18 | Bionomics Limited | Cyclic compounds as receptor modulating therapeutics and methods and uses thereof |
CN114585362B (zh) * | 2019-09-23 | 2024-05-07 | 生态有限公司 | 治疗制剂及其用途 |
JP7570388B2 (ja) | 2022-10-25 | 2024-10-21 | 株式会社熊平製作所 | 電気式施解錠装置及び開閉装置 |
Family Cites Families (79)
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GB1022214A (en) * | 1963-01-31 | 1966-03-09 | Sterling Drug Inc | Novel 1,3-disubstituted-1,4-dihydro-4-oxo-1,7-naphthyridines and their preparation |
US3429887A (en) | 1965-01-26 | 1969-02-25 | Sterling Drug Inc | 1,7-naphthyridine-3-carboxylic acid derivatives and their preparation |
US3506668A (en) * | 1965-01-26 | 1970-04-14 | Sterling Drug Inc | Method of preparing 8-hydroxy-quinolines |
JPS5023037B1 (da) | 1970-12-29 | 1975-08-05 | ||
JPS5023036B1 (da) | 1970-12-29 | 1975-08-05 | ||
JPS5023037A (da) | 1973-07-03 | 1975-03-12 | ||
JPS5023036A (da) * | 1973-07-06 | 1975-03-12 | ||
JPS5132594A (en) * | 1974-09-11 | 1976-03-19 | Kanebo Ltd | 1 88 nafuchirijinjudotai no seiho |
JPS5331690A (en) * | 1976-09-01 | 1978-03-25 | Shionogi & Co Ltd | Oxadithiacephalosporins |
JPS54163596A (en) * | 1978-06-09 | 1979-12-26 | Daiichi Seiyaku Co | Flonaphlizine derivative |
JPS55111486A (en) * | 1979-02-19 | 1980-08-28 | Dai Ichi Seiyaku Co Ltd | Preparation of pro 3,2,-b -1,8-naphthyridine derivative |
JPS55151584A (en) * | 1979-05-11 | 1980-11-26 | Dai Ichi Seiyaku Co Ltd | Preparation of 1,8-naphthyridine derivative |
JPS56115787A (en) * | 1980-02-19 | 1981-09-11 | Dai Ichi Seiyaku Co Ltd | Preparation of furo (3,2-b)(1,8)naphthyridine derivative |
JPS56118083A (en) * | 1980-02-22 | 1981-09-16 | Dai Ichi Seiyaku Co Ltd | Furo(3,2-b)(1,8)naphthyridine derivative |
JPS56118081A (en) * | 1980-02-22 | 1981-09-16 | Dai Ichi Seiyaku Co Ltd | Preparation of 6-methoxy-1,8-naphthyridine |
JPS5726688A (en) | 1980-07-24 | 1982-02-12 | Dai Ichi Seiyaku Co Ltd | Furo 3,2-b 1,8-naphthyridine-7-carboxylic acid derivative |
JPS57109790A (en) * | 1980-12-26 | 1982-07-08 | Dai Ichi Seiyaku Co Ltd | Furo(3,2-b)1,8-naphthyridine-7-carboxylic acid derivative |
US4404201A (en) * | 1981-11-13 | 1983-09-13 | Warner-Lambert Company | Cephalosporins |
JPS5993080A (ja) * | 1982-11-18 | 1984-05-29 | Sumitomo Chem Co Ltd | 1,5−ナフチリジンカルボン酸誘導体 |
DE68919273T2 (de) * | 1988-05-10 | 1995-03-23 | Ici Pharma | Cephalosporine, Verfahren zu ihrer Herstellung und pharmazeutische Präparate. |
US5095015A (en) | 1990-07-24 | 1992-03-10 | Neurogen Corporation | Certain azacycloalkyl imidazopyrimidines; a new class of gaba brain receptor ligands |
US5182290A (en) | 1991-08-27 | 1993-01-26 | Neurogen Corporation | Certain oxazoloquinolinones; a new class of GABA brain receptor ligands |
US5182386A (en) | 1991-08-27 | 1993-01-26 | Neurogen Corporation | Certain imidazoquinoxalinones; a new class of gaba brain receptor ligands |
IT1251202B (it) * | 1991-09-13 | 1995-05-04 | Mediolanum Farmaceutici Spa | 6-amminochinoloni, sintesi ed impiego come antibatterici |
US5212310A (en) | 1991-12-19 | 1993-05-18 | Neurogen Corporation | Certain aryl fused imidazopyrimidines; a new class of GABA brain receptor ligands |
US5306819A (en) | 1992-08-27 | 1994-04-26 | Neurogen Corporation | Certain aryl a cycloalkyl fused imidazopyrazinols; and new class of GABA brain receptor ligands |
US5750702A (en) | 1993-10-27 | 1998-05-12 | Neurogen Corporation | Certain pyrrolo pyridine-3-carboxamides; a new class of GABA brain receptor ligands |
US5484944A (en) | 1993-10-27 | 1996-01-16 | Neurogen Corporation | Certain fused pyrrolecarboxanilides and their use as GABA brain receptor ligands |
US6211365B1 (en) | 1996-01-19 | 2001-04-03 | Neurogen Corporation | Fused pyrrolecarboxamides; a new class of GABA brain receptor ligands |
US5804686A (en) | 1996-01-19 | 1998-09-08 | Neurogen Corporation | fused pyrrolecarboxamides; a new class of GABA brain receptor ligands |
US6013650A (en) | 1996-03-14 | 2000-01-11 | Neurogen Corporation | Certain aryl fused imidazopyrimidines; a new class of GABA brain receptor ligands |
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US6143760A (en) | 1997-08-25 | 2000-11-07 | Neurogen Corporation | Substituted 4-oxo-napthyridine-3-carboxamides: GABA brain receptor ligands |
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DE19826050A1 (de) | 1998-06-12 | 1999-12-16 | Bayer Ag | Verfahren zur Herstellung von Chinolon- und Naphthyridoncarbonsäuren und deren Ester |
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US6297256B1 (en) | 1999-06-15 | 2001-10-02 | Neurogen Corporation | Aryl and heteroaryl substituted pyridino derivatives GABA brain receptor ligands |
CA2388593A1 (en) | 1999-11-12 | 2001-05-17 | Neurogen Corporation | Bicyclic and tricyclic heteroaromatic compounds |
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US6423956B1 (en) | 2000-07-28 | 2002-07-23 | Optical Biopsy Technologies | Fiber-coupled, high-speed, integrated, angled-dual-axis confocal scanning microscopes employing vertical cross-section scanning |
JP2004506038A (ja) | 2000-08-16 | 2004-02-26 | ニューロゲン コーポレイション | 2,4−置換ピリジン誘導体 |
MXPA03001945A (es) | 2000-09-06 | 2003-09-10 | Neurogen Corp | Tetrahidroindazoles sustituidos con arilo y su uso como ligandos para el receptor gaba-a. |
US20020151591A1 (en) | 2000-10-17 | 2002-10-17 | Anabella Villalobos | Combination use of acetylcholinesterase inhibitors and GABAa inverse agonists for the treatment of cognitive disorders |
AUPR283801A0 (en) | 2001-02-01 | 2001-03-01 | Australian National University, The | Chemical compounds and methods |
EP1363606A1 (en) | 2001-03-01 | 2003-11-26 | Pfizer Products Inc. | Use of gaba[a] inverse agonists in combination with nicotine receptor partial agonists, estrogen, selective estrogen modulators or vitamin e for the treatment of coginitive disorders |
MXPA03008681A (es) | 2001-03-27 | 2004-04-02 | Neurogen Corp | (oxo-pirazol[1,5]pirimidin-2-il)alquil-carboxamidas. |
US7084156B2 (en) | 2001-11-27 | 2006-08-01 | Merck & Co., Inc. | 2-Aminoquinoline compounds |
AU2002352868A1 (en) | 2001-11-27 | 2003-06-10 | Merck & Co., Inc. | 4-aminoquinoline compounds |
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US20070293492A1 (en) | 2004-12-03 | 2007-12-20 | Devita Robert J | Quinoline Tachykinin Receptor Antagonists |
MX2007014929A (es) | 2005-06-02 | 2008-02-15 | Hoffmann La Roche | 3-metansulfonilquinolinas como mejoradores de gaba-b. |
ES2392181T3 (es) | 2005-09-29 | 2012-12-05 | Sanofi | Derivados de fenil-[1,2,4]-oxadiazol-5-ona con grupo fenilo, procesos para su preparación y su uso como productos farmacéuticos |
US20080044390A1 (en) | 2006-08-11 | 2008-02-21 | Xiaowei Jin | Methods and compositions for the treatment of neurodegenerative disorders |
PT2074123E (pt) | 2006-10-16 | 2013-01-22 | Bionomics Ltd | Novos compostos ansiolíticos |
AR076687A1 (es) | 2009-05-18 | 2011-06-29 | Infinity Pharmaceuticals Inc | Isoxazolinas como inhibidores de la amidahidrolasa de acidos grasos y com-posiciones farmaceuticas que los contienen |
DK2672823T3 (da) | 2011-02-07 | 2016-11-28 | Biogen Ma Inc | S1p-modulerende midler |
CA2828780A1 (en) | 2011-03-02 | 2012-09-07 | Bionomics Limited | Novel small-molecules as therapeutics |
US20140051701A1 (en) | 2011-03-02 | 2014-02-20 | Bionomics Limited | Methods of treating a disease or condition of the central nervous system |
AU2012253237B2 (en) | 2011-05-12 | 2015-09-24 | Bionomics Limited | Methods for preparing naphthyridines |
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2007
- 2007-10-16 PT PT78153715T patent/PT2074123E/pt unknown
- 2007-10-16 JP JP2009531697A patent/JP5373613B2/ja active Active
- 2007-10-16 AU AU2007312936A patent/AU2007312936B2/en active Active
- 2007-10-16 CA CA2954376A patent/CA2954376C/en active Active
- 2007-10-16 EP EP12186384.9A patent/EP2540722B1/en active Active
- 2007-10-16 ES ES07815371T patent/ES2399071T3/es active Active
- 2007-10-16 CA CA2666219A patent/CA2666219C/en active Active
- 2007-10-16 US US12/311,872 patent/US8293737B2/en active Active
- 2007-10-16 WO PCT/AU2007/001566 patent/WO2008046135A1/en active Application Filing
- 2007-10-16 EP EP07815371A patent/EP2074123B1/en active Active
- 2007-10-16 NZ NZ576036A patent/NZ576036A/en not_active IP Right Cessation
- 2007-10-16 PL PL07815371T patent/PL2074123T3/pl unknown
- 2007-10-16 SI SI200731109T patent/SI2074123T1/sl unknown
- 2007-10-16 DK DK07815371.5T patent/DK2074123T3/da active
-
2009
- 2009-12-15 HK HK09111778.6A patent/HK1132268A1/xx unknown
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2012
- 2012-09-14 US US13/617,153 patent/US8551990B2/en active Active
- 2012-09-14 US US13/617,317 patent/US8614212B2/en active Active
-
2013
- 2013-05-20 JP JP2013106650A patent/JP5739476B2/ja active Active
- 2013-09-18 US US14/030,808 patent/US8906912B2/en active Active
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2014
- 2014-11-05 US US14/533,808 patent/US9573945B2/en active Active
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2015
- 2015-04-23 JP JP2015088672A patent/JP6138191B2/ja active Active
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2017
- 2017-01-04 US US15/398,472 patent/US9975892B2/en active Active
- 2017-02-08 JP JP2017021529A patent/JP6506322B2/ja active Active
- 2017-12-15 US US15/844,295 patent/US10233181B2/en active Active
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