DK1524993T3 - Neisseria-vaccinesammensætning omfattende en kombination af antigener - Google Patents
Neisseria-vaccinesammensætning omfattende en kombination af antigenerInfo
- Publication number
- DK1524993T3 DK1524993T3 DK03784153.3T DK03784153T DK1524993T3 DK 1524993 T3 DK1524993 T3 DK 1524993T3 DK 03784153 T DK03784153 T DK 03784153T DK 1524993 T3 DK1524993 T3 DK 1524993T3
- Authority
- DK
- Denmark
- Prior art keywords
- antigens
- combination
- vaccine composition
- neisseria
- neisseria vaccine
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/104—Pseudomonadales, e.g. Pseudomonas
- A61K39/1045—Moraxella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0218035A GB0218035D0 (en) | 2002-08-02 | 2002-08-02 | Vaccine composition |
GB0218036A GB0218036D0 (en) | 2002-08-02 | 2002-08-02 | Vaccine |
GB0218037A GB0218037D0 (en) | 2002-08-02 | 2002-08-02 | Vaccine composition |
GB0218051A GB0218051D0 (en) | 2002-08-02 | 2002-08-02 | Vaccine composition |
GBGB0220199.4A GB0220199D0 (en) | 2002-08-30 | 2002-08-30 | Mutant protein and refolding method |
GBGB0220197.8A GB0220197D0 (en) | 2002-08-30 | 2002-08-30 | Refolding method |
GB0225524A GB0225524D0 (en) | 2002-11-01 | 2002-11-01 | Vaccine composition |
GB0225531A GB0225531D0 (en) | 2002-11-01 | 2002-11-01 | Vaccine |
GB0230170A GB0230170D0 (en) | 2002-12-24 | 2002-12-24 | Vaccine |
GB0230168A GB0230168D0 (en) | 2002-12-24 | 2002-12-24 | Vaccine composition |
GB0230164A GB0230164D0 (en) | 2002-12-24 | 2002-12-24 | Vaccine composition |
GB0305028A GB0305028D0 (en) | 2003-03-05 | 2003-03-05 | Vaccine |
PCT/EP2003/008571 WO2004014418A2 (en) | 2002-08-02 | 2003-07-31 | Neisserial vaccine compositions comprising a combination of antigens |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1524993T3 true DK1524993T3 (da) | 2013-06-03 |
Family
ID=31722002
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03784153.3T DK1524993T3 (da) | 2002-08-02 | 2003-07-31 | Neisseria-vaccinesammensætning omfattende en kombination af antigener |
DK10177890.0T DK2255826T3 (da) | 2002-08-02 | 2003-07-31 | Neisseria-vaccinesammensætninger omfattende en kombination af antigener. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10177890.0T DK2255826T3 (da) | 2002-08-02 | 2003-07-31 | Neisseria-vaccinesammensætninger omfattende en kombination af antigener. |
Country Status (26)
Country | Link |
---|---|
US (9) | US7838014B2 (da) |
EP (11) | EP2258386A3 (da) |
JP (7) | JP4740738B2 (da) |
KR (6) | KR101237329B1 (da) |
CN (2) | CN1671413A (da) |
AU (6) | AU2003260357B2 (da) |
CA (4) | CA2493124C (da) |
CO (3) | CO5680454A2 (da) |
CY (3) | CY1114243T1 (da) |
DE (2) | DE20321890U1 (da) |
DK (2) | DK1524993T3 (da) |
ES (3) | ES2575014T3 (da) |
HK (1) | HK1077014A1 (da) |
HU (1) | HUE029200T2 (da) |
IL (3) | IL165660A0 (da) |
IS (3) | IS7593A (da) |
LU (1) | LU92262I2 (da) |
MX (3) | MXPA05000842A (da) |
MY (1) | MY149591A (da) |
NO (3) | NO20050008L (da) |
NZ (4) | NZ574530A (da) |
PL (5) | PL375382A1 (da) |
PT (2) | PT1524993E (da) |
SI (2) | SI2255826T1 (da) |
TW (1) | TWI360424B (da) |
WO (4) | WO2004015099A2 (da) |
Families Citing this family (139)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999057280A2 (en) | 1998-05-01 | 1999-11-11 | Chiron Corporation | Neisseria meningitidis antigens and compositions |
US10967045B2 (en) * | 1998-11-02 | 2021-04-06 | Secretary of State for Health and Social Care | Multicomponent meningococcal vaccine |
GB9823978D0 (en) * | 1998-11-02 | 1998-12-30 | Microbiological Res Authority | Multicomponent meningococcal vaccine |
BR0010130A (pt) | 1999-04-30 | 2002-06-04 | Chiron Spa | Antìgenos de neisseria conservados |
EP2258851A1 (en) * | 1999-05-19 | 2010-12-08 | Novartis Vaccines and Diagnostics S.r.l. | Combination neisserial compositions |
GB9918319D0 (en) * | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
PT2275554E (pt) | 1999-10-29 | 2015-06-26 | Novartis Vaccines & Diagnostic | Péptidos antigénicos de neisseria |
GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
US7947291B2 (en) * | 2000-01-25 | 2011-05-24 | The University Of Queensland | Modified surface antigen |
AU2001239478B2 (en) | 2000-02-28 | 2007-05-17 | Glaxosmithkline Biologicals S.A. | Hybrid expression of neisserial proteins |
US6936261B2 (en) | 2000-07-27 | 2005-08-30 | Children's Hospital & Research Center At Oakland | Vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis |
GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
JP4592284B2 (ja) | 2001-07-27 | 2010-12-01 | カイロン ソチエタ ア レスポンサビリタ リミタータ | 髄膜炎菌付着因子 |
GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
DK1524993T3 (da) * | 2002-08-02 | 2013-06-03 | Glaxosmithkline Biolog Sa | Neisseria-vaccinesammensætning omfattende en kombination af antigener |
GB0220194D0 (en) * | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
US8663656B2 (en) * | 2002-10-11 | 2014-03-04 | Novartis Ag | Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages |
GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
EP1615945B1 (en) | 2003-04-09 | 2011-09-28 | BioGeneriX AG | Glycopegylation methods and proteins/peptides produced by the methods |
GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
US9005625B2 (en) | 2003-07-25 | 2015-04-14 | Novo Nordisk A/S | Antibody toxin conjugates |
US8329192B2 (en) | 2003-09-19 | 2012-12-11 | Epitopix Llc | Campylobacter polypeptides and methods of use |
ATE506963T1 (de) | 2003-10-02 | 2011-05-15 | Novartis Vaccines & Diagnostic | Kombinationsimpfstoffe gegen meningitis |
GB0323709D0 (en) * | 2003-10-09 | 2003-11-12 | Health Prot Agency | Modified whole cell,cell extract and omv-based vaccines |
US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
EP1706481A2 (en) * | 2003-12-23 | 2006-10-04 | GlaxoSmithKline Biologicals S.A. | Vaccine |
GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
JP5174457B2 (ja) | 2004-05-11 | 2013-04-03 | デ スタート デール ネーダーランデン, フェルテヘンウォールディヒィト ドール デ ミニステール ファン フォルクスヘーゾンドハイド, フェルザイン アン スポルト | アジュバントとしての髄膜炎菌lgtBLOS |
US20080300173A1 (en) | 2004-07-13 | 2008-12-04 | Defrees Shawn | Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1] |
GB0419408D0 (en) * | 2004-09-01 | 2004-10-06 | Chiron Srl | 741 chimeric polypeptides |
GB0419627D0 (en) * | 2004-09-03 | 2004-10-06 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
CA2585758C (en) | 2004-10-29 | 2017-08-01 | Neose Technologies, Inc. | Remodeling and glycopegylation of fibroblast growth factor (fgf) |
GB0428381D0 (en) * | 2004-12-24 | 2005-02-02 | Isis Innovation | Vaccine |
NZ556436A (en) | 2005-01-10 | 2010-11-26 | Biogenerix Ag | Glycopegylated granulocyte colony stimulating factor |
EP1848732B1 (en) * | 2005-01-21 | 2016-07-27 | Epitopix, LLC | Yersinia spp. polypeptides and methods of use |
CN101107007B (zh) | 2005-01-27 | 2011-08-17 | 奥克兰儿童医院及研究中心 | 对脑膜炎奈瑟球菌所致疾病具有广谱保护作用的gna1870囊泡疫苗 |
EP2386571B1 (en) | 2005-04-08 | 2016-06-01 | ratiopharm GmbH | Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants |
KR101351873B1 (ko) * | 2005-06-27 | 2014-02-17 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 면역원성 조성물 |
US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
US7955817B2 (en) | 2005-09-02 | 2011-06-07 | Glaxosmithkline Biologicals S.A. | Vaccine protection assay |
JP5047969B2 (ja) * | 2005-09-05 | 2012-10-10 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 髄膜炎菌特異的抗血清に対する血清殺菌アッセイ |
US20090048440A1 (en) | 2005-11-03 | 2009-02-19 | Neose Technologies, Inc. | Nucleotide Sugar Purification Using Membranes |
GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
EP1962902A2 (en) * | 2005-12-06 | 2008-09-03 | Universita Degli Studi di Padova | Methods and compositions relating to adhesins as adjuvants |
GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
EP3470080A1 (en) | 2005-12-22 | 2019-04-17 | GlaxoSmithKline Biologicals S.A. | Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates |
CU23549A1 (es) * | 2005-12-29 | 2010-07-20 | Ct Ingenieria Genetica Biotech | Composiciones farmacéuticas que contienen la proteína nma0939 |
PH12013500136A1 (en) | 2006-03-30 | 2015-03-13 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
DE602007003596D1 (de) | 2006-06-12 | 2010-01-14 | Glaxosmithkline Biolog Sa | Impfstoff |
CN101516388B (zh) | 2006-07-21 | 2012-10-31 | 诺和诺德公司 | 通过o-联糖基化序列的肽的糖基化 |
CN103585624A (zh) | 2006-09-07 | 2014-02-19 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗 |
EP2054521A4 (en) | 2006-10-03 | 2012-12-19 | Novo Nordisk As | PROCESS FOR CLEANING POLYPEPTIDE CONJUGATES |
GB0700136D0 (en) | 2007-01-04 | 2007-02-14 | Glaxosmithkline Biolog Sa | Process for manufacturing vaccines |
GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
JP2010523582A (ja) | 2007-04-03 | 2010-07-15 | バイオジェネリクス アクチェンゲゼルシャフト | グリコpeg化g−csfを用いた治療方法 |
EP2170919B8 (en) | 2007-06-12 | 2016-01-20 | ratiopharm GmbH | Improved process for the production of nucleotide sugars |
MX2009013949A (es) | 2007-06-26 | 2010-05-24 | Glaxosmithkline Biolog Sa | Vacuna que comprende conjugados de polisacárido capsular de streptococcus pneumoniae. |
WO2009038889A1 (en) * | 2007-08-02 | 2009-03-26 | Children's Hospital And Research Center At Oakland | Fhbp- and lpxl1-based vesicle vaccines for broad spectrum protection against diseases caused by neisseria meningitidis |
EP2185727A2 (en) * | 2007-08-02 | 2010-05-19 | GlaxoSmithKline Biologicals SA | Novel method |
MX340096B (es) | 2007-10-19 | 2016-06-27 | Glaxosmithkline Biologicals Sa | Formulaciones de vacuna meningococica. |
EP2245048B1 (en) | 2008-02-21 | 2014-12-31 | Novartis AG | Meningococcal fhbp polypeptides |
CN103497247A (zh) | 2008-02-27 | 2014-01-08 | 诺沃—诺迪斯克有限公司 | 缀合的因子viii分子 |
EA018068B1 (ru) | 2008-03-03 | 2013-05-30 | Айрм Ллк | Соединения и композиции в качестве модуляторов активности tlr |
UA99659C2 (uk) * | 2008-05-30 | 2012-09-10 | Дзе Ю.Ес.Ей., Ес Репрезентед Бай Дзе Секретарі Оф Дзе Армі, Он Бехаф Оф Уолтер Рід Армі | Мультивалентна вакцина з нативних везикул зовнішньої мембрани менінгококів, способи її застосування |
KR101042541B1 (ko) * | 2008-07-25 | 2011-06-17 | 한국생명공학연구원 | 외막소체를 생산하는 재조합 g(-) 박테리아 및 이를이용한 다가항원이 실린 외막소체의 제조방법 |
US20110182981A1 (en) * | 2008-08-25 | 2011-07-28 | Peixuan Zhu | Gonococcal vaccines |
GB0816447D0 (en) * | 2008-09-08 | 2008-10-15 | Glaxosmithkline Biolog Sa | Vaccine |
GB0822634D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Meningitis vaccines |
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