EP1438323A4 - MENINGOCOQUE COMPOSITIONS COMPRISING AN ADJUVANT - Google Patents

MENINGOCOQUE COMPOSITIONS COMPRISING AN ADJUVANT

Info

Publication number: EP1438323A4
Authority: EP; European Patent Office
Prior art keywords: meningocoque; adjuvant; compositions; meningocoque compositions
Prior art date: 2001-10-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP02800481A

Other languages

German (de)

French (fr)

Other versions

EP1438323A2 (en

Inventor

Derek O'hagan

Nicholas Valiante

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis Vaccines and Diagnostics Inc

Original Assignee

Novartis Vaccines and Diagnostics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-03

Filing date

2002-10-03

Publication date

2007-08-01

2002-04-05 Priority claimed from PCT/US2002/010869 external-priority patent/WO2002080648A2/en

2002-10-03 Application filed by Novartis Vaccines and Diagnostics Inc filed Critical Novartis Vaccines and Diagnostics Inc

2004-07-21 Publication of EP1438323A2 publication Critical patent/EP1438323A2/en

2007-08-01 Publication of EP1438323A4 publication Critical patent/EP1438323A4/en

Status Withdrawn legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Epidemiology (AREA)
Oncology (AREA)
Microbiology (AREA)
Mycology (AREA)
Bioinformatics & Cheminformatics (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Biological Depolymerization Polymers (AREA)
Compositions Of Macromolecular Compounds (AREA)

EP02800481A 2001-10-03 2002-10-03 MENINGOCOQUE COMPOSITIONS COMPRISING AN ADJUVANT Withdrawn EP1438323A4 (en)

Applications Claiming Priority (13)

Application Number	Priority Date	Filing Date	Title
US254438		1988-10-06
US32692901P	2001-10-03	2001-10-03
US326929P		2001-10-03
PCT/US2002/010869 WO2002080648A2 (en)	2001-04-05	2002-04-05	Mucosal boosting following parenteral priming
WOPCT/US02/10869		2002-04-05
US37354702P	2002-04-17	2002-04-17
US373547P		2002-04-17
US38067702P	2002-05-13	2002-05-13
US380677P		2002-05-13
US25443802A	2002-09-24	2002-09-24
US0230423		2002-09-24
WOPCT/US02/30423		2002-09-24
PCT/US2002/031726 WO2003028661A2 (en)	2001-10-03	2002-10-03	Adjuvanted meningococcus compositions

Publications (2)

Publication Number	Publication Date
EP1438323A2 EP1438323A2 (en)	2004-07-21
EP1438323A4 true EP1438323A4 (en)	2007-08-01

Family

ID=32601151

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP02800481A Withdrawn EP1438323A4 (en)	2001-10-03	2002-10-03	MENINGOCOQUE COMPOSITIONS COMPRISING AN ADJUVANT

Country Status (8)

Country	Link
EP (1)	EP1438323A4 (en)
JP (1)	JP4522699B2 (en)
CN (1)	CN100354297C (en)
AU (1)	AU2002334844B2 (en)
BR (1)	BR0213119A (en)
CA (1)	CA2462646C (en)
NZ (1)	NZ532274A (en)
WO (1)	WO2003028661A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0115176D0 (en)	2001-06-20	2001-08-15	Chiron Spa	Capular polysaccharide solubilisation and combination vaccines
GB0302218D0 (en)	2003-01-30	2003-03-05	Chiron Sri	Vaccine formulation & Mucosal delivery
MXPA04011249A (en) *	2002-05-14	2005-06-06	Chiron Srl	Mucosal vaccines with chitosan adjuvant and meningococcal antigens.
MY149591A (en) *	2002-08-02	2013-09-13	Glaxosmithkline Biolog Sa	Vaccines comprising l2 and/or l3 los from neisseria
CA2511512C (en)	2002-12-27	2013-10-29	Chiron Corporation	Immunogenic compositions containing phospholipid
CA2514328C (en) *	2003-01-30	2020-01-14	Chiron Srl	Injectable vaccines against multiple meningococcal serogroups
WO2004075829A2 (en) *	2003-01-30	2004-09-10	Chiron Corporation	Adjuvanted influenza vaccine
US7731967B2 (en)	2003-04-30	2010-06-08	Novartis Vaccines And Diagnostics, Inc.	Compositions for inducing immune responses
DE602004022286D1 (en)	2003-06-02	2009-09-10	Novartis Vaccines & Diagnostic	IMMUNOGENIC COMPOSITIONS BASED ON BIODEGRADABLE MICRO PARTICLES CONTAINING A DIPHTHERIA AND TETANO TOXOID
CA2555105A1 (en) *	2004-02-20	2005-09-09	Hybridon, Inc.	Potent mucosal immune response induced by modified immunomodulatory oligonucleotides
ES2434029T3 (en) *	2004-11-15	2013-12-13	Novartis Vaccines And Diagnostics, Inc.	Immunogenic compositions containing anthrax antigen, biodegradable polymer microparticles, and immunological adjuvant containing polynucleotide
AU2006207891C1 (en)	2005-01-28	2011-09-01	Galen Bio, Inc.	Immunologically active compositions
WO2006092607A1 (en) *	2005-03-02	2006-09-08	The Secretary Of State For Defence	Pharmaceutical composition
EP2244695A1 (en)	2007-12-07	2010-11-03	Novartis AG	Compositions for inducing immune responses
CN101559225B (en) *	2008-04-18	2012-07-11	北京生物制品研究所	Meningococcus vaccine
AU2013278056B2 (en) *	2012-06-21	2018-07-05	Northwestern University	Peptide conjugated particles

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6239116B1 (en) *	1994-07-15	2001-05-29	University Of Iowa Research Foundation	Immunostimulatory nucleic acid molecules
BR9813930A (en) *	1997-11-06	2006-12-19	Chiron Spa	neisserial antigen
WO1999036544A2 (en) *	1998-01-14	1999-07-22	Chiron S.P.A.	Neisseria meningitidis antigens
CN101293920B (en) *	1998-05-01	2012-07-18	诺华疫苗和诊断公司	Neisseria meningitidis antigens and compositions
PT1100468E (en) *	1998-07-29	2006-07-31	Chiron Corp	MICROPARTICLES WITH ADSORVENT SURFACES, PROCESSES OF MANUFACTURE AND USE OF THE SAME
JP2004511201A (en) *	1998-10-09	2004-04-15	カイロン　コーポレイション	Neisseria genome sequences and methods of using them
AU2457100A (en) *	1999-02-26	2000-09-14	Chiron S.P.A.	Enhancement of bactericidal activity of neisseria antigens with oligonucleotidescontaining cg motifs
AU2875700A (en) *	1999-02-26	2000-09-14	Chiron Corporation	Microemulsions with adsorbed macromoelecules and microparticles
JP2003518363A (en) *	1999-04-30	2003-06-10	カイロンエセ．ピー．アー．	Conserved Neisseria antigen
CN100339482C (en) *	2000-02-28	2007-09-26	启龙股份公司	Hybrid expression of neisserial proteins

2002
- 2002-10-03 CN CNB028241282A patent/CN100354297C/en not_active Expired - Fee Related
- 2002-10-03 WO PCT/US2002/031726 patent/WO2003028661A2/en active IP Right Grant
- 2002-10-03 BR BR0213119-6A patent/BR0213119A/en not_active IP Right Cessation
- 2002-10-03 AU AU2002334844A patent/AU2002334844B2/en not_active Ceased
- 2002-10-03 NZ NZ532274A patent/NZ532274A/en not_active IP Right Cessation
- 2002-10-03 JP JP2003531997A patent/JP4522699B2/en not_active Expired - Fee Related
- 2002-10-03 CA CA2462646A patent/CA2462646C/en not_active Expired - Fee Related
- 2002-10-03 EP EP02800481A patent/EP1438323A4/en not_active Withdrawn

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
O'HAGAN D T ET AL: "POLY(LACTIDE-CO-GLYCOLIDE) MICROPARTICLES FOR THE DEVELOPMENT OF SINGLE-DOSE CONTROLLED-RELEASE VACCINES", ADVANCED DRUG DELIVERY REVIEWS, AMSTERDAM, NL, vol. 32, 1998, pages 225 - 246, XP000944990, ISSN: 0169-409X *
SINGH M ET AL: "ADVANCES IN VACCINE ADJUVANTS", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 17, no. 11, November 1999 (1999-11-01), pages 1075 - 1081, XP000941305, ISSN: 1087-0156 *
SINGH M ET AL: "Cationic microparticles are an effective delivery system for immunie stimulatory CpG DNA", PHARMACEUTICAL RESEARCH, NEW YORK, NY, US, vol. 18, no. 10, October 2001 (2001-10-01), pages 1476 - 1479, XP002976979, ISSN: 0724-8741 *

Also Published As

Publication number	Publication date
WO2003028661A3 (en)	2003-10-09
CN1599746A (en)	2005-03-23
BR0213119A (en)	2004-12-28
JP2005526697A (en)	2005-09-08
JP4522699B2 (en)	2010-08-11
WO2003028661A2 (en)	2003-04-10
CA2462646A1 (en)	2003-04-10
EP1438323A2 (en)	2004-07-21
CN100354297C (en)	2007-12-12
NZ532274A (en)	2006-02-24
CA2462646C (en)	2013-02-12
AU2002334844B8 (en)	2003-04-14
AU2002334844B2 (en)	2007-08-02

Publication	Publication Date	Title
EP1438074A4 (en)	2007-08-01	ADJUVANT COMPOSITIONS
FI20010780A0 (en)	2001-04-12	Improved compositions
ATE303787T1 (en)	2005-09-15	SHEARGEL COMPOSITIONS
DK1390066T3 (en)	2012-07-16	vaccine Composition
AR028197A1 (en)	2003-04-30	ANTITRANSPIRING COMPOSITIONS
IS6915A (en)	2003-08-15	composition
PT1139764E (en)	2005-09-30	ADJUVANT COMPOSITION
BR0210619A (en)	2006-05-23	composition
EP1426029A4 (en)	2009-12-30	Emulsion compositions
IS7081A (en)	2003-12-16	composition
EP1438323A4 (en)	2007-08-01	MENINGOCOQUE COMPOSITIONS COMPRISING AN ADJUVANT
ATE369830T1 (en)	2007-09-15	SWEAT-INHIBITING COMPOSITIONS
ATE314049T1 (en)	2006-01-15	SWEAT-INHIBITING COMPOSITIONS
EG23126A (en)	2004-04-28	Novel fungicial compositions
EP1420818A4 (en)	2008-07-02	ANTIGENIC COMPOSITIONS
PT1238587E (en)	2005-10-31	BIOPESTICIDES COMPOSITIONS
ITMI20010954A0 (en)	2001-05-10	IODURATION PROCEDURE
GB0114532D0 (en)	2001-08-08	Novel compositions
NO20032086L (en)	2003-07-07	Adjuvant combination formulations
NO20020524D0 (en)	2002-02-01	Stabilized Organic-Peroxide Compositions
ITTO20020747A0 (en)	2002-08-23	COMPOSITION
ITTO20020745A0 (en)	2002-08-23	COMPOSITION
ITRC20010003A1 (en)	2001-05-22	"FUMANELLO"
ATE271600T1 (en)	2004-08-15	SOLID COMPOSITION
SE0101369D0 (en)	2001-04-17	Free 4 ever

Legal Events

Date	Code	Title	Description
2004-06-04	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2004-07-21	17P	Request for examination filed	Effective date: 20040420
2004-07-21	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
2004-07-21	AX	Request for extension of the european patent	Extension state: AL LT LV MK RO SI
2007-01-24	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC.
2007-08-01	A4	Supplementary search report drawn up and despatched	Effective date: 20070704
2007-08-01	RIC1	Information provided on ipc code assigned before grant	Ipc: A61K 39/385 20060101ALI20070628BHEP Ipc: A61K 39/095 20060101ALI20070628BHEP Ipc: A61K 39/02 20060101AFI20070628BHEP
2010-11-17	17Q	First examination report despatched	Effective date: 20101020
2014-10-10	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2014-11-12	18D	Application deemed to be withdrawn	Effective date: 20140501