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CY1625A - Podophyllotoxin derivatives - Google Patents

Podophyllotoxin derivatives Download PDF

Info

Publication number
CY1625A
CY1625A CY1625A CY162592A CY1625A CY 1625 A CY1625 A CY 1625A CY 1625 A CY1625 A CY 1625A CY 162592 A CY162592 A CY 162592A CY 1625 A CY1625 A CY 1625A
Authority
CY
Cyprus
Prior art keywords
compound
formula
substituted
alkyl
pharmaceutically acceptable
Prior art date
Application number
CY1625A
Other languages
English (en)
Inventor
Mark G Saulnier
Peter D Senter
John F Kadow
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of CY1625A publication Critical patent/CY1625A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Cable Accessories (AREA)
CY1625A 1987-08-04 1992-07-10 Podophyllotoxin derivatives CY1625A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8149387A 1987-08-04 1987-08-04
US07/199,731 US4904768A (en) 1987-08-04 1988-05-27 Epipodophyllotoxin glucoside 4'-phosphate derivatives

Publications (1)

Publication Number Publication Date
CY1625A true CY1625A (en) 1992-07-10

Family

ID=26765636

Family Applications (1)

Application Number Title Priority Date Filing Date
CY1625A CY1625A (en) 1987-08-04 1992-07-10 Podophyllotoxin derivatives

Country Status (34)

Country Link
US (3) US4904768A (sk)
JP (1) JPH0699465B2 (sk)
KR (1) KR900006230B1 (sk)
CN (1) CN1027169C (sk)
AT (1) AT398974B (sk)
BE (1) BE1002982A4 (sk)
CA (1) CA1310637C (sk)
CH (1) CH676716A5 (sk)
CY (1) CY1625A (sk)
CZ (1) CZ286893B6 (sk)
DD (2) DD299067A5 (sk)
DE (1) DE3826562A1 (sk)
DK (2) DK169344B1 (sk)
ES (1) ES2010775A6 (sk)
FI (1) FI87790C (sk)
FR (1) FR2622193B1 (sk)
GB (1) GB2207674B (sk)
GR (1) GR1000490B (sk)
HK (1) HK6392A (sk)
HU (3) HU208147B (sk)
IE (1) IE61040B1 (sk)
IL (1) IL87290A (sk)
IT (1) IT1226825B (sk)
LU (2) LU87290A1 (sk)
MX (1) MX173843B (sk)
MY (1) MY104321A (sk)
NL (2) NL192683C (sk)
NO (4) NO170284C (sk)
NZ (1) NZ225615A (sk)
PT (1) PT88186B (sk)
SE (1) SE502214C2 (sk)
SG (1) SG101291G (sk)
SK (1) SK541288A3 (sk)
YU (3) YU143688A (sk)

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US6610299B1 (en) 1989-10-19 2003-08-26 Aventis Pharma Deutschland Gmbh Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates
US7241595B2 (en) 1989-10-20 2007-07-10 Sanofi-Aventis Pharma Deutschland Gmbh Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates
US6475486B1 (en) 1990-10-18 2002-11-05 Aventis Pharma Deutschland Gmbh Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates
US5552154A (en) * 1989-11-06 1996-09-03 The Stehlin Foundation For Cancer Research Method for treating cancer with water-insoluble s-camptothecin of the closed lactone ring form and derivatives thereof
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US5648474A (en) * 1991-10-08 1997-07-15 Bristol-Myers Squibb Crystalline etoposide 4'-phosphate diethanolate
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US5459248A (en) * 1993-11-04 1995-10-17 Bristol-Myers Squibb Company Process of preparing etoposide phosphate and etoposide
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CA2491310C (en) 2002-07-15 2015-10-06 Board Of Regents, The University Of Texas System Compositions comprising cell-impermeant duramycin derivatives
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FR1171314A (fr) * 1955-05-13 1959-01-23 Sandoz Ag Produits de condensation de glucosides avec des composés carbonyliques et leur préparation
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FR2397425A1 (fr) * 1977-07-11 1979-02-09 Rhone Poulenc Ind Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent
EP0111058B1 (en) * 1982-11-26 1987-11-04 Nippon Kayaku Kabushiki Kaisha Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof
US4567253A (en) * 1984-02-03 1986-01-28 Tony Durst 2-Substituted derivatives of podophyllotoxin and etoposide
JPS60208910A (ja) * 1984-03-31 1985-10-21 Green Cross Corp:The 水難溶性薬物・リン脂質複合体の製造方法
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Also Published As

Publication number Publication date
LU87290A1 (fr) 1990-02-07
SK279325B6 (sk) 1998-10-07
LU90138I2 (fr) 1997-11-26
IL87290A0 (en) 1989-01-31
ES2010775A6 (es) 1989-12-01
FI87790C (fi) 1993-02-25
NL970042I2 (sk) 2005-06-01
SE502214C2 (sv) 1995-09-18
PT88186A (pt) 1989-06-30
NO883299L (no) 1989-02-24
GB2207674A (en) 1989-02-08
FR2622193A1 (fr) 1989-04-28
DE3826562A1 (de) 1989-02-16
AT398974B (de) 1995-02-27
GR880100512A (en) 1989-05-25
US4904768A (en) 1990-02-27
NL8801934A (nl) 1989-03-01
NO920665D0 (no) 1992-02-20
SG101291G (en) 1992-01-17
SE8802815D0 (sv) 1988-08-03
NL192683C (nl) 1997-12-02
DD274423A5 (de) 1989-12-20
GB8818462D0 (en) 1988-09-07
USRE35524E (en) 1997-06-03
MY104321A (en) 1994-03-31
DE3826562C2 (sk) 1993-04-08
HU905862D0 (en) 1991-03-28
CN1027169C (zh) 1994-12-28
DK11992D0 (da) 1992-01-31
DK169344B1 (da) 1994-10-10
NL192683B (sk) 1997-08-01
CN1061225A (zh) 1992-05-20
ATA195588A (de) 1994-07-15
IE882378L (en) 1989-02-04
CZ286893B6 (cs) 2000-07-12
PT88186B (pt) 1995-07-03
AU610619B2 (en) 1991-05-23
IT1226825B (it) 1991-02-19
JPH0699465B2 (ja) 1994-12-07
NO920665L (no) 1989-02-24
IL87290A (en) 1993-01-31
US5041424A (en) 1991-08-20
JPH01100188A (ja) 1989-04-18
IT8821535A0 (it) 1988-07-28
NO172440B (no) 1993-04-13
AU2030688A (en) 1989-06-08
NZ225615A (en) 1991-06-25
NO1998002I1 (no) 1998-01-14
BE1002982A4 (fr) 1991-10-15
MX173843B (es) 1994-03-30
DK434088D0 (da) 1988-08-03
CA1310637C (en) 1992-11-24
FI883596A0 (fi) 1988-08-01
NO170284B (no) 1992-06-22
HUT47303A (en) 1989-02-28
YU10390A (en) 1990-06-30
DD299067A5 (de) 1992-03-26
FI883596A (fi) 1989-02-05
KR900006230B1 (ko) 1990-08-27
SK541288A3 (en) 1998-10-07
NO920277D0 (no) 1992-01-22
SE8802815L (sv) 1989-02-05
HU208147B (en) 1993-08-30
NO172440C (no) 1993-07-21
NL970042I1 (nl) 1998-03-02
CZ541288A3 (cs) 1999-12-15
NO920277L (no) 1989-02-24
DK434088A (da) 1989-02-05
CH676716A5 (sk) 1991-02-28
DK11992A (da) 1992-01-31
IE61040B1 (en) 1994-09-07
GB2207674B (en) 1991-09-11
FR2622193B1 (fr) 1993-12-17
KR890003790A (ko) 1989-04-18
HU202547B (en) 1991-03-28
HU211960A9 (en) 1996-01-29
YU143688A (en) 1990-04-30
GR1000490B (el) 1992-07-30
FI87790B (fi) 1992-11-13
NO170284C (no) 1992-09-30
YU10490A (en) 1990-06-30
HK6392A (en) 1992-01-17
NO883299D0 (no) 1988-07-26
MX9202851A (es) 1992-06-30

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