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CY1110992T1 - ΣΥΝΔΥΑΣΜΕΝΕΣ ΣΥΝΘΕΣΕΙΣ ΠΟΥ ΠΕΡΙΕΧΟΥΝ (Ε)-7-[4-(4-ΦΘΟΡΟΦΑΙΝΥΛ)-6-ΙΣΟΠΡΟΠΥΛ-2-[ΜΕΘΥΛ(ΜΕΘΥΛΣΟΥΛΦΟΝΥΛ)ΑΜΙΝΟ]ΠΥΡΙΜΙΔΙΝ-5-ΥΛ](3r,5s)-3,5-ΔΙΥΔΡΟΞΥΕΠΤ-6-ΕΝΟΪΚΟ ΟΞΥ - Google Patents

ΣΥΝΔΥΑΣΜΕΝΕΣ ΣΥΝΘΕΣΕΙΣ ΠΟΥ ΠΕΡΙΕΧΟΥΝ (Ε)-7-[4-(4-ΦΘΟΡΟΦΑΙΝΥΛ)-6-ΙΣΟΠΡΟΠΥΛ-2-[ΜΕΘΥΛ(ΜΕΘΥΛΣΟΥΛΦΟΝΥΛ)ΑΜΙΝΟ]ΠΥΡΙΜΙΔΙΝ-5-ΥΛ](3r,5s)-3,5-ΔΙΥΔΡΟΞΥΕΠΤ-6-ΕΝΟΪΚΟ ΟΞΥ

Info

Publication number
CY1110992T1
CY1110992T1 CY20101101157T CY101101157T CY1110992T1 CY 1110992 T1 CY1110992 T1 CY 1110992T1 CY 20101101157 T CY20101101157 T CY 20101101157T CY 101101157 T CY101101157 T CY 101101157T CY 1110992 T1 CY1110992 T1 CY 1110992T1
Authority
CY
Cyprus
Prior art keywords
methylsulfonyl
fluorophenyl
pyridyl
isopropyl
amino
Prior art date
Application number
CY20101101157T
Other languages
English (en)
Inventor
Norman Eugene Cameron
Mary Anne Cotter
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9902591.8A external-priority patent/GB9902591D0/en
Priority claimed from GBGB9902594.2A external-priority patent/GB9902594D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CY1110992T1 publication Critical patent/CY1110992T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται σε φαρμακευτικούς συνδυασμούς και φαρμακευτικές συνθέσεις ενός φαρμάκου στατίνης και άλλων παραγόντων που χρησιμοποιούνται για τη θεραπευτική αντιμετώπιση του διαβήτη ή των επιπλοκών του διαβήτη.
CY20101101157T 1999-02-06 2010-12-16 ΣΥΝΔΥΑΣΜΕΝΕΣ ΣΥΝΘΕΣΕΙΣ ΠΟΥ ΠΕΡΙΕΧΟΥΝ (Ε)-7-[4-(4-ΦΘΟΡΟΦΑΙΝΥΛ)-6-ΙΣΟΠΡΟΠΥΛ-2-[ΜΕΘΥΛ(ΜΕΘΥΛΣΟΥΛΦΟΝΥΛ)ΑΜΙΝΟ]ΠΥΡΙΜΙΔΙΝ-5-ΥΛ](3r,5s)-3,5-ΔΙΥΔΡΟΞΥΕΠΤ-6-ΕΝΟΪΚΟ ΟΞΥ CY1110992T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9902591.8A GB9902591D0 (en) 1999-02-06 1999-02-06 Pharmaceutical compositions
GBGB9902594.2A GB9902594D0 (en) 1999-02-06 1999-02-06 Pharmaceutical compositions
EP07008956A EP1897546B1 (en) 1999-02-06 2000-02-01 Combined compositions comprising (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3r,5s)-3,5-dihydroxyhept-6-enoic acid

Publications (1)

Publication Number Publication Date
CY1110992T1 true CY1110992T1 (el) 2015-06-11

Family

ID=26315085

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20071101207T CY1106879T1 (el) 1999-02-06 2007-09-19 Χρηση των αναστολεων αναγωγασης συνενζυμου α 3-υδροξυ-3-μεθυλογλουταρυλ για την παρασκευη ενος φαρμακου για την αντιμετωπιση της διαβητικης νευροπαθειας
CY20101101157T CY1110992T1 (el) 1999-02-06 2010-12-16 ΣΥΝΔΥΑΣΜΕΝΕΣ ΣΥΝΘΕΣΕΙΣ ΠΟΥ ΠΕΡΙΕΧΟΥΝ (Ε)-7-[4-(4-ΦΘΟΡΟΦΑΙΝΥΛ)-6-ΙΣΟΠΡΟΠΥΛ-2-[ΜΕΘΥΛ(ΜΕΘΥΛΣΟΥΛΦΟΝΥΛ)ΑΜΙΝΟ]ΠΥΡΙΜΙΔΙΝ-5-ΥΛ](3r,5s)-3,5-ΔΙΥΔΡΟΞΥΕΠΤ-6-ΕΝΟΪΚΟ ΟΞΥ

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20071101207T CY1106879T1 (el) 1999-02-06 2007-09-19 Χρηση των αναστολεων αναγωγασης συνενζυμου α 3-υδροξυ-3-μεθυλογλουταρυλ για την παρασκευη ενος φαρμακου για την αντιμετωπιση της διαβητικης νευροπαθειας

Country Status (34)

Country Link
US (4) US6894058B1 (el)
EP (2) EP1897546B1 (el)
JP (3) JP2002536332A (el)
KR (1) KR100699757B1 (el)
CN (1) CN1196488C (el)
AR (1) AR025512A1 (el)
AT (2) ATE367162T1 (el)
AU (1) AU763970B2 (el)
BR (1) BR0007996A (el)
CA (1) CA2368186C (el)
CY (2) CY1106879T1 (el)
CZ (2) CZ302893B6 (el)
DE (2) DE60045168D1 (el)
DK (2) DK1150678T3 (el)
EE (2) EE05556B1 (el)
ES (2) ES2352803T3 (el)
GB (1) GB0001662D0 (el)
HK (2) HK1041223A1 (el)
HU (1) HU227642B1 (el)
IL (3) IL144730A0 (el)
IS (2) IS2793B (el)
MX (1) MXPA01007821A (el)
MY (1) MY138289A (el)
NO (1) NO330400B1 (el)
NZ (3) NZ525419A (el)
PL (1) PL198098B1 (el)
PT (2) PT1150678E (el)
RU (1) RU2239456C2 (el)
SI (2) SI1897546T1 (el)
SK (2) SK286854B6 (el)
TR (1) TR200102229T2 (el)
TW (1) TWI230067B (el)
WO (1) WO2000045818A1 (el)
ZA (1) ZA200105885B (el)

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Also Published As

Publication number Publication date
PL350312A1 (en) 2002-12-02
ES2286995T3 (es) 2007-12-16
SI1897546T1 (sl) 2011-02-28
CY1106879T1 (el) 2012-05-23
ZA200105885B (en) 2002-10-17
CA2368186A1 (en) 2000-08-10
SK286854B6 (sk) 2009-06-05
NO20013812L (no) 2001-10-02
KR100699757B1 (ko) 2007-03-27
NZ513061A (en) 2003-06-30
CZ302881B6 (cs) 2012-01-04
EP1150678B1 (en) 2007-07-18
NZ525419A (en) 2004-12-24
PL198098B1 (pl) 2008-05-30
EP1897546A1 (en) 2008-03-12
CN1196488C (zh) 2005-04-13
IS2820B (is) 2012-12-15
RU2239456C2 (ru) 2004-11-10
AU2304700A (en) 2000-08-25
CZ302893B6 (cs) 2012-01-11
IL208330A0 (en) 2010-12-30
EP1897546B1 (en) 2010-10-27
CA2368186C (en) 2008-06-03
DE60045168D1 (de) 2010-12-09
IL144730A (en) 2010-12-30
NO330400B1 (no) 2011-04-04
IS6016A (is) 2001-07-20
EE200100405A (et) 2002-10-15
HK1118209A1 (en) 2009-02-06
MXPA01007821A (es) 2004-08-19
MY138289A (en) 2009-05-29
TWI230067B (en) 2005-04-01
IS2793B (is) 2012-08-15
EP1150678A1 (en) 2001-11-07
IS8978A (is) 2011-08-23
PT1897546E (pt) 2010-12-15
AU763970B2 (en) 2003-08-07
CN1338937A (zh) 2002-03-06
HUP0105138A2 (hu) 2002-04-29
HK1041223A1 (en) 2002-07-05
ATE485823T1 (de) 2010-11-15
NO20013812D0 (no) 2001-08-03
US20090186908A1 (en) 2009-07-23
SK287792B6 (sk) 2011-10-04
US20050209128A1 (en) 2005-09-22
DK1150678T3 (da) 2007-10-08
ES2352803T3 (es) 2011-02-23
SK11102001A3 (sk) 2002-05-09
GB0001662D0 (en) 2000-03-15
EE201200015A (et) 2012-10-15
EE05556B1 (et) 2012-08-15
WO2000045818A1 (en) 2000-08-10
TR200102229T2 (tr) 2001-12-21
EE05621B1 (et) 2013-02-15
HUP0105138A3 (en) 2002-11-28
US20120041010A1 (en) 2012-02-16
PT1150678E (pt) 2007-09-14
IL144730A0 (en) 2002-06-30
HU227642B1 (en) 2011-10-28
DE60035575T2 (de) 2008-04-03
JP2012051898A (ja) 2012-03-15
KR20010089635A (ko) 2001-10-06
JP2002536332A (ja) 2002-10-29
BR0007996A (pt) 2001-10-30
DE60035575D1 (de) 2007-08-30
SI1150678T1 (sl) 2008-02-29
CZ20012806A3 (cs) 2002-02-13
DK1897546T3 (da) 2011-01-17
US6894058B1 (en) 2005-05-17
JP2014065718A (ja) 2014-04-17
NZ536433A (en) 2006-08-31
ATE367162T1 (de) 2007-08-15
AR025512A1 (es) 2002-12-04

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