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IS2793B - Notkun á 3-hýdroxý-3-metýlglútarýl hjálparensíms A afsýringarkljúfshindrum til framleiðslunnar á lyfi til að meðhöndla sykursýkitaugakvilla - Google Patents

Notkun á 3-hýdroxý-3-metýlglútarýl hjálparensíms A afsýringarkljúfshindrum til framleiðslunnar á lyfi til að meðhöndla sykursýkitaugakvilla

Info

Publication number
IS2793B
IS2793B IS6016A IS6016A IS2793B IS 2793 B IS2793 B IS 2793B IS 6016 A IS6016 A IS 6016A IS 6016 A IS6016 A IS 6016A IS 2793 B IS2793 B IS 2793B
Authority
IS
Iceland
Prior art keywords
methylglutaryl
antacid
medicament
inhibitors
hydroxy
Prior art date
Application number
IS6016A
Other languages
English (en)
Other versions
IS6016A (is
Inventor
Norman E Cameron
Mary A Cotter
Original Assignee
Astrazeneca Ab
Univ Aberdeen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9902594.2A external-priority patent/GB9902594D0/en
Priority claimed from GBGB9902591.8A external-priority patent/GB9902591D0/en
Application filed by Astrazeneca Ab, Univ Aberdeen filed Critical Astrazeneca Ab
Publication of IS6016A publication Critical patent/IS6016A/is
Publication of IS2793B publication Critical patent/IS2793B/is

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IS6016A 1999-02-06 2001-07-20 Notkun á 3-hýdroxý-3-metýlglútarýl hjálparensíms A afsýringarkljúfshindrum til framleiðslunnar á lyfi til að meðhöndla sykursýkitaugakvilla IS2793B (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9902594.2A GB9902594D0 (en) 1999-02-06 1999-02-06 Pharmaceutical compositions
GBGB9902591.8A GB9902591D0 (en) 1999-02-06 1999-02-06 Pharmaceutical compositions
PCT/GB2000/000280 WO2000045818A1 (en) 1999-02-06 2000-02-01 Use of 3-hydroxy-3-methylglutaryl coenzym a reductase inhibitors for the manufacture of a medicament for the treatment of diabetic neuropathy

Publications (2)

Publication Number Publication Date
IS6016A IS6016A (is) 2001-07-20
IS2793B true IS2793B (is) 2012-08-15

Family

ID=26315085

Family Applications (2)

Application Number Title Priority Date Filing Date
IS6016A IS2793B (is) 1999-02-06 2001-07-20 Notkun á 3-hýdroxý-3-metýlglútarýl hjálparensíms A afsýringarkljúfshindrum til framleiðslunnar á lyfi til að meðhöndla sykursýkitaugakvilla
IS8978A IS2820B (is) 1999-02-06 2011-08-23 Samsettar samsetningar sem ná yfir (E)-7-[4-(4-flúorofenýl)-6-ísóprópyl-2-[metýl(metýlsúlfónýl)-amínó]pýrimídín-5-ýl](3R,5S)-3,5-díhýdroxýhept-6-enósýru

Family Applications After (1)

Application Number Title Priority Date Filing Date
IS8978A IS2820B (is) 1999-02-06 2011-08-23 Samsettar samsetningar sem ná yfir (E)-7-[4-(4-flúorofenýl)-6-ísóprópyl-2-[metýl(metýlsúlfónýl)-amínó]pýrimídín-5-ýl](3R,5S)-3,5-díhýdroxýhept-6-enósýru

Country Status (33)

Country Link
US (4) US6894058B1 (is)
EP (2) EP1150678B1 (is)
JP (3) JP2002536332A (is)
KR (1) KR100699757B1 (is)
CN (1) CN1196488C (is)
AR (1) AR025512A1 (is)
AT (2) ATE485823T1 (is)
AU (1) AU763970B2 (is)
BR (1) BR0007996A (is)
CA (1) CA2368186C (is)
CY (2) CY1106879T1 (is)
CZ (2) CZ302893B6 (is)
DE (2) DE60035575T2 (is)
DK (2) DK1150678T3 (is)
EE (2) EE05621B1 (is)
ES (2) ES2286995T3 (is)
GB (1) GB0001662D0 (is)
HU (1) HU227642B1 (is)
IL (3) IL144730A0 (is)
IS (2) IS2793B (is)
MX (1) MXPA01007821A (is)
MY (1) MY138289A (is)
NO (1) NO330400B1 (is)
NZ (3) NZ525419A (is)
PL (1) PL198098B1 (is)
PT (2) PT1150678E (is)
RU (1) RU2239456C2 (is)
SI (2) SI1150678T1 (is)
SK (2) SK287792B6 (is)
TR (1) TR200102229T2 (is)
TW (1) TWI230067B (is)
WO (1) WO2000045818A1 (is)
ZA (1) ZA200105885B (is)

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DE10025308A1 (de) * 2000-05-23 2001-11-29 Bayer Ag Kombination von Cerivastatin mit ACE Inhibitoren und ihre Verwendung in Arzneimitteln
PE20020617A1 (es) * 2000-08-22 2002-08-05 Novartis Ag Composicion que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina o un sensibilizante a la insulina
AR030379A1 (es) * 2000-08-22 2003-08-20 Novartis Ag Combinaciones
US20060089389A1 (en) 2000-08-22 2006-04-27 Malcolm Allison Combination
HUP0303353A3 (en) * 2000-10-12 2004-10-28 Kowa Co Preventives and remedies for complications of diabetes
KR20040025874A (ko) * 2000-10-18 2004-03-26 화이자 프로덕츠 인크. 스타틴 및 소르비톨 탈수소효소 억제제의 조합
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US20030171407A1 (en) * 2002-03-07 2003-09-11 Upsher-Smith Laboratories, Inc. Composition for reducing blood glucose and cholesterol
US20030199424A1 (en) * 2002-03-20 2003-10-23 Smith Maree Therese Method of treatment and/or prophylaxis
TW200810743A (en) * 2002-03-22 2008-03-01 Novartis Ag Combination of organic compounds
JP4395633B2 (ja) * 2002-08-29 2010-01-13 学校法人鈴鹿医療科学大学 非神経細胞の神経細胞への分化成熟法、該組成物と該組成物探索法
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US20090082407A1 (en) * 2004-06-18 2009-03-26 Biostratum, Inc. Pyridoxamine for the Treatment of Diabetic Kidney Disease
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US20050054731A1 (en) * 2003-09-08 2005-03-10 Franco Folli Multi-system therapy for diabetes, the metabolic syndrome and obesity
AU2003269484A1 (en) * 2003-09-11 2005-03-29 Biocon Limited Salt of atorvastatin with metformin
GB0322552D0 (en) * 2003-09-26 2003-10-29 Astrazeneca Uk Ltd Therapeutic treatment
AU2003272084A1 (en) * 2003-10-07 2005-04-21 Biocon Limited SALT OF 1,2,6,7,8,8A-HEXAHYDRO-Beta,Delta,6-TRIHYDROXY-2-METHYL-8-((2S)-2-METHYL-1-OXOBUTOXY)-, (BetaR,Delta R,1S,2S,6S,8S,8AR)- 1-NAPHTHALENEHEPTANOIC ACID WITH N,N-DIMETHYL-IMIDODICARBONIMIDIC DIAMIDE
KR100715114B1 (ko) * 2005-02-19 2007-05-10 한국유나이티드제약 주식회사 당뇨병 치료를 위한 약학적 조성물
CN101632673B (zh) * 2008-07-24 2011-08-10 鲁南制药集团股份有限公司 含有氯沙坦、吡格列酮和瑞舒伐他汀的药物组合物及其新用途
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WO2015053589A1 (ko) * 2013-10-11 2015-04-16 가톨릭대학교 산학협력단 메트포민 및 스타틴의 복합제를 이용한 자가면역질환의 예방 또는 치료용 조성물
KR101579656B1 (ko) * 2013-12-12 2015-12-22 가천대학교 산학협력단 프라바스타틴과 발사르탄을 포함하는 약학 조성물
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Also Published As

Publication number Publication date
RU2239456C2 (ru) 2004-11-10
EP1150678B1 (en) 2007-07-18
EE200100405A (et) 2002-10-15
KR20010089635A (ko) 2001-10-06
NO330400B1 (no) 2011-04-04
CA2368186C (en) 2008-06-03
EE201200015A (et) 2012-10-15
TR200102229T2 (tr) 2001-12-21
KR100699757B1 (ko) 2007-03-27
CN1338937A (zh) 2002-03-06
CY1110992T1 (el) 2015-06-11
IS2820B (is) 2012-12-15
HUP0105138A2 (hu) 2002-04-29
ES2352803T3 (es) 2011-02-23
IL144730A0 (en) 2002-06-30
NZ536433A (en) 2006-08-31
HK1118209A1 (en) 2009-02-06
NO20013812D0 (no) 2001-08-03
US20090186908A1 (en) 2009-07-23
MXPA01007821A (es) 2004-08-19
DE60045168D1 (de) 2010-12-09
PL350312A1 (en) 2002-12-02
SI1150678T1 (sl) 2008-02-29
ZA200105885B (en) 2002-10-17
CY1106879T1 (el) 2012-05-23
EP1150678A1 (en) 2001-11-07
HU227642B1 (en) 2011-10-28
CZ302893B6 (cs) 2012-01-11
HUP0105138A3 (en) 2002-11-28
DE60035575T2 (de) 2008-04-03
CN1196488C (zh) 2005-04-13
IS8978A (is) 2011-08-23
US20120041010A1 (en) 2012-02-16
TWI230067B (en) 2005-04-01
PT1897546E (pt) 2010-12-15
DK1897546T3 (da) 2011-01-17
CA2368186A1 (en) 2000-08-10
MY138289A (en) 2009-05-29
GB0001662D0 (en) 2000-03-15
JP2014065718A (ja) 2014-04-17
CZ20012806A3 (cs) 2002-02-13
IL208330A0 (en) 2010-12-30
IS6016A (is) 2001-07-20
SK11102001A3 (sk) 2002-05-09
NZ525419A (en) 2004-12-24
US6894058B1 (en) 2005-05-17
ATE367162T1 (de) 2007-08-15
NZ513061A (en) 2003-06-30
CZ302881B6 (cs) 2012-01-04
SK286854B6 (sk) 2009-06-05
PL198098B1 (pl) 2008-05-30
EP1897546B1 (en) 2010-10-27
WO2000045818A1 (en) 2000-08-10
EP1897546A1 (en) 2008-03-12
DE60035575D1 (de) 2007-08-30
JP2012051898A (ja) 2012-03-15
DK1150678T3 (da) 2007-10-08
PT1150678E (pt) 2007-09-14
IL144730A (en) 2010-12-30
SK287792B6 (sk) 2011-10-04
US20050209128A1 (en) 2005-09-22
EE05556B1 (et) 2012-08-15
ES2286995T3 (es) 2007-12-16
NO20013812L (no) 2001-10-02
ATE485823T1 (de) 2010-11-15
SI1897546T1 (sl) 2011-02-28
AU2304700A (en) 2000-08-25
JP2002536332A (ja) 2002-10-29
BR0007996A (pt) 2001-10-30
EE05621B1 (et) 2013-02-15
AR025512A1 (es) 2002-12-04
HK1041223A1 (en) 2002-07-05
AU763970B2 (en) 2003-08-07

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