CN1299714C - Method for preparing traditional Chinese compound ointment - Google Patents

Abstract

The present invention relates to Chinese medicinal compound ointment which is mainly composed of coptis root, Chinese gall and other auxiliary materials. The present invention also has a preparation method that the coptis root is pulverized for standby, the Chinese gall is warmly soaked and concentrated into powder by way of spray drying, and ointment is prepared after the two drugs are added into simple ointment substrates. Substances that are prepared with the method can be used for treating dermatosis.

Description

A kind of preparation method of traditional Chinese medicine compound ointment

Technical Field The present invention relates to a compound traditional Chinese medicine ointment, which is mainly composed of Coptis chinensis, gallnut and other auxiliary materials.

Background Art Baby red buttocks is a common pediatric disease, and bed sores are a common disease in long-term bedridden patients, which bothers many patients. There are not many traditional Chinese medicines clinically used for the above two diseases. Among traditional Chinese medicines, Galla galla has the function of reducing dampness and sores, and Coptis chinensis has the functions of clearing away heat and dampness, purging fire and detoxifying. The ointment can directly act on the human body through transdermal absorption, and the preparation method is mostly that the medicinal material is directly used as a medicine or is made into an extract after water extraction and alcohol precipitation, and then made into an ointment. Therefore, preparing a medicine that can be used for infant red buttocks and decubitus and adopting a new traditional Chinese medicine preparation method can provide more clinical choices.

SUMMARY OF THE INVENTION The purpose of the present invention is to establish a new preparation method of traditional Chinese medicine compound ointment, and the medicine prepared by it can be used to treat skin diseases.

The technical scheme of the invention is: an ointment, which is composed of 1 part of Coptidis rhizome and 2 to 4 parts of Chinese gallnut, and the others are medicinal ointment base materials. The auxiliary materials can be: magnesium stearate, paraffin wax, liquid paraffin wax, lanolin and other ointment bases. Its preparation method is:

(1) Take Coptidis Rhizome. After crushing, sieve and set aside;

(2) Get Galla gall, soak in warm water after crushing, collect the leachate, filter, remove impurities, the filtrate is concentrated through a thin film to obtain a concentrated solution, and the resulting solution is spray-dried to make a powder for subsequent use;

(3) Prepare a single ointment base.

(4) Add the medicinal materials in steps (1) and (2) into the single ointment base of (3), add an appropriate amount of essence, and stir evenly to prepare an ointment.

Wherein the pulverizing method described in step (1) can be ultrafine pulverization, passing through a 100-200 mesh sieve.

Wherein the temperature of the water soaking described in the step (2) can be 40-60° C., and the soaking time can be 24-72 hours.

In the spray drying described in step (2), the inlet temperature may be 160-220° C., the outlet air temperature may be 80-120° C., and the feed pump frequency may be 30-80 Hz.

Wherein the method for preparing single ointment base described in step (3) can be: get 5～8 parts of stearic acid, 1～3 parts of paraffin wax, 2～4 parts of liquid paraffin wax, 1～2 parts of anhydrous lanolin , heated and melted, filtered, and kept at 70-75°C to obtain substance A; additionally take 1-2 parts of glycerin, 1-2 parts of triethanolamine, appropriate amount of preservatives and distilled water, heat and dissolve, and keep warm at 70-75°C to obtain substance B; Substances A.B were thoroughly mixed under stirring to prepare a matrix.

Compared with the prior art, the present invention adopts the compound preparation of Galla gall and Coptis chinensis, and adopts a new technology, and the prepared substance can be used for the treatment of skin diseases.

Specific embodiments The present invention will be further described below in conjunction with a plurality of specific embodiments:

Each gallnut 100g was taken, compared with different warm soaking times and warm soaking temperatures, and the leaching rate was used as an index: Soaking time (hours) Soaking temperature (℃) Leaching rate 24244848 45554555 36% 43% 42% 45%

Take the concentrated solution, conduct experiments according to different inlet and outlet temperatures, and compare the properties and water content of the powder. Inlet air temperature Outlet temperature Properties and water content 180190200215 81879295 General properties, with adhesion phenomenon, relatively high water content. Good shape, less sticky, relatively low water content. The character is good, with a small amount of burnt yellow, relatively dry. The properties are good, with a small amount of charring.

Adopted multiple auxiliary materials to carry out the preparation of single matrix ointment, adopting method is as follows (unit is gram): plan Substance A Substance B Magnesium stearate Paraffin liquid paraffin Anhydrous lanolin glycerin Triethanolamine 1234 150150200200 6030030 908010080 2030200 50606050 30304040

The above four kinds of schemes have all been prepared into single matrix ointment by using conventional ointment preparation methods.

Claims (8)

1. An ointment for treating skin diseases, characterized in that: it is prepared from the extract powder and medicinal ointment matrix adjuvant obtained after the Coptidis rhizome powder of 1 weight part and Gallnut gallnut of 2 to 4 weight parts are extracted and processed . 2. The ointment for treating skin diseases according to claim 1, wherein the auxiliary material is: magnesium stearate, paraffin wax, liquid paraffin wax or lanolin. 3. as claimed in claim 1 or 2, be used for the preparation method of the ointment for the treatment of dermatosis, it is characterized in that: (1) Get Coptis Rhizoma, sieve after crushing, and set aside; (2) Get Galla gall, soak in warm water after crushing, collect the leachate, filter, remove impurities, the filtrate is concentrated through a thin film to obtain a concentrated solution, and the resulting solution is spray-dried to make a powder for subsequent use; (3) preparing a single ointment base; (4) Add the medicinal materials in steps (1), (2) to the single ointment base of (3), and Add an appropriate amount of essence and stir evenly to prepare an ointment. 4. According to the preparation method of the ointment for treating skin diseases according to claim 3, it is characterized in that: the pulverization method of Coptis Rhizoma is superfine pulverization. 5. According to the preparation method of the ointment for treating skin diseases according to claim 3, it is characterized in that: the water soaking temperature described in step (2) is 40-60° C., and the soaking time is 24-48 hours. 6. according to the preparation method of the ointment that is used for the treatment of dermatosis described in claim 3, it is characterized in that: the spray drying described in step (2), its inlet air temperature is 160～220 ℃, and air outlet temperature is 80 ~120°C, feed pump frequency is 30~80Hz. 7. according to the preparation method of the ointment that is used for the treatment of dermatosis described in claim 3, it is characterized in that: the method for preparing single ointment base described in step (3) is: get stearic acid 5～8 weight parts, 1-3 parts by weight of paraffin wax, 2-4 parts by weight of liquid paraffin wax, 1-2 parts by weight of anhydrous lanolin, heated and melted, filtered, and kept at 70-75°C to obtain substance A; additionally take 1-2 parts by weight of glycerin 1-2 parts by weight of triethanolamine, an appropriate amount of preservative and distilled water, heated and dissolved, and kept at 70-75°C to obtain substance B; under stirring state, substances A·B were fully mixed to obtain a matrix. 8. The application of the ointment for treating skin diseases as claimed in claim 1 or 2, characterized in that: the application of the ointment in the preparation of medicines for treating skin diseases.