CN107837315A - A kind of Chinese medicine composition for treating the fungal infection of the hand and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating the fungal infection of the hand and preparation method thereof Download PDFInfo
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- CN107837315A CN107837315A CN201711133544.5A CN201711133544A CN107837315A CN 107837315 A CN107837315 A CN 107837315A CN 201711133544 A CN201711133544 A CN 201711133544A CN 107837315 A CN107837315 A CN 107837315A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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Abstract
The present invention relates to a kind of Chinese medicine composition for treating the fungal infection of the hand and preparation method thereof.The Chinese medicine is prepared by the raw material including following parts by weight:Camphor tree oil, lemon are by oil, Baeckea frutescens oil, MEIHUA BINGPIAN, tea-seed oil.Chinese medicine composition provided by the invention is curative for effect, security is good, is free from side effects in terms of the fungal infection of the hand is treated, and it is easy to use, cost is low, effect is better than prior art.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition for treating the fungal infection of the hand and preparation method thereof.
Background technology
The fungal infection of the hand is the Superficial mycoses of hand.Gained the name because of the coarse dry and cracked palm such as goose of its hand.Men and women, old and young can obtain
Disease, but between twenty and fifty more common.Southern sough is higher than the northern Arid Area incidence of disease, often concurrent with eczema.This disease is more
Send out in the centre of the palm and finger.Common blister of its skin lesion summer or rotten to the corn sepage, winter show as the scales of skin that peel off and dry chap.It is modern
Medical science is referred to as the tinea manuum.
Doctor trained in Western medicine thinks, caused by this disease system infects because of the dermatophyte between being grown on palm and referring to, mainly Trichophyton rubrum,
Alpha fungus and acrothesium floccosum.
Diagnosis and treatment:
1st, rheumatism accumulates skin card:Palm refers to a blister as brilliant, and dry up dry furfur, and boundary is obvious, expands gradually, or refers to a flush, wet
Rotten, itch, tongue is red, Tai Bai or greasy, slippery.The hot clearing damp of wind and heat dispersing.
2nd, skin syndrome of dampness-heat:Blister cluster, itch unbearably, micro- sense cusalgia, scratch flowing water, contamination is in blocks, low-grade fever sweating, mouth
Thirst without desire to drink, red tongue with yellowish and greasy fur, soft and rapid pulse or sliding number.Clearing heat and expelling damp.
3rd, syndrome of wind and dryness due to blood deficiency:Skin of palm of hand plumpness is coarse, dry, cracking, or blister does not show, and dry up exfoliation, pink tongue tongue
Thin, arteries and veins is thin.Enriching the blood to restore normal menstruation.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for treating the fungal infection of the hand;
The purpose of the present invention is realized by following technical scheme:
The Chinese medicine composition of the treatment fungal infection of the hand of the present invention, is prepared by the raw material including following parts by weight:
Camphor tree oil 30-50 parts, lemon are by oily 30-50 parts, Baeckea frutescens oil 10-30 parts, MEIHUA BINGPIAN 10-30 parts, tea-seed oil 5-20 parts.
Preferably, it is to be prepared by the raw material including following parts by weight:
Camphor tree oil 35-45 parts, lemon are by oily 35-45 parts, Baeckea frutescens oil 15-25 parts, MEIHUA BINGPIAN 15-25 parts, tea-seed oil 10-15
Part.
Camphor tree oil, for the root of Sterculiaceae plant Chinese parasol tree, wind-damp dispelling, and blood vessels, degrading the channel.Control pain in rheumatoid joints, intestines wind
Lower blood, irregular menstruation, traumatic injury.
Camphor tree oil, it is volatile oil of the canella camphor tree through evaporation extraction.Toil, temperature.Wind-dispelling, dehumidify, analgesic, desinsection.Control
Treating rheumatic ostealgia, traumatic injury, mange.
Lemon is by oil, volatilizations of the Myrtaceae eucalyptus citriodora Eucalyptus Citriodora Hook. f. through evaporation extraction
Oil.Hardship, temperature.External application decoct soup washes boil, controls all diseases of skin and rheumatalgia.It is among the people with dysentery is controlled, again for extraction eucalyptus oil raw material.
Baeckea frutescens oil, volatile oil of the Myrtaceae baeckea frutescen platymiscium baeckea frutescen Baeckea frutescens L. through evaporation extraction.
It is pungent, bitter, puckery, it is cool.Wind dehumidifies, diuresis of detoxifying, antalgesic-antipruritic.
MEIHUA BINGPIAN, for the native crystal compound separated out in the resin of Spore density borneo camphor tree.It is pungent;It is bitter;
The cool thoughts of returning home;Lung channel;Inducing resuscitation of having one's ideas straightened out;Radiating analgesic;Shade removing.Main apoplexy lockjaw;Pyreticosis coma;Frightened epilepsy phlegm fan;Deafness with qi stagnation;
Conjunctivitis;Larynx numbness;Aphtha;Carbuncle swells;Hemorrhoid;Enterobiasis.
Tea-seed oil, the fruit ribes of plant of theaceae tea are through oily made from refinement.Fall fire dispelling phlegm to stop asthma.Main phlegm heat panting is coughed;
Brains ring.
The Chinese medicine composition of the present invention, its active component is to be mixed with each raw material to form.
The Chinese medicine composition of the treatment fungal infection of the hand of the present invention, it can be made each with pharmaceutically acceptable carrier combination
Kind of conventional external preparation, as liniment, granule, lotion, tincture, finish, paste,(It is soft)Paste, press agent etc..
The pharmaceutically acceptable carrier of the present invention includes but is not limited to following:
Diluent:Distilled water, ethanol etc..
Cosolvent:The polyalcohols such as glycerine, sorbierite.
Preservative:Benzoic acid, sodium benzoate, propionic acid, parabens, ethyl-para-hydroxybenzoate etc..
Oleaginous base:Vaseline, liquid paraffin, lanolin, beeswax, animal oil, vegetable oil, glycerin monostearate,
Octadecyl alcolol etc. and its mixture,
Water-soluble base:Glycerine, sodium alginate, carbopol resin, starch gelatin, methylcellulose, sodium carboxymethylcellulose,
Polyethylene glycol, polyvinyl alcohol.
Transdermal enhancer:Cutin moisturizing diuretin, pyrrolones derivative, linoleic acid, laruyl alcohol, tween, dodecyl front three
Base ammonium bromide, dodecyl sodium sulfate, lauryl sodium sulfate, menthol, Laurocapram(Azone)Deng.
For example, it can be prepared as various common exterior-applied formulations by one of following method:
Method 1:Granule
Scheme one is taken to add granule and often use auxiliary material, routinely production method is prepared into one of to the gained active component of scheme three
Granule of the present invention.
Above-mentioned granule often includes one of diluent, wetting agent, adhesive, disintegrant or whole with auxiliary material.
Method 2:Liniment
Scheme one is taken to add liniment and often use auxiliary material one of to the gained active component of scheme three, routinely production method is prepared into
Invention liniment.
Above-mentioned liniment often includes one of diluent, preservative, cosolvent, transdermal enhancer or whole with auxiliary material.
Method 3:Paste
Scheme one is taken to add paste and often use auxiliary material one of to the gained active component of scheme three, routinely production method is prepared into
Invention paste.
Above-mentioned paste often includes one of oleaginous base, water-soluble base, preservative, transdermal enhancer or whole with auxiliary material.
Method 4:Lotion
Scheme one is taken after dilution, to add water to stir evenly, after standing filtering, produce one of to the gained active component of scheme three.
A kind of Chinese medicine composition for treating the fungal infection of the hand provided by the invention has advantages below:
1st, composition provided by the invention is safe and effective, has clearing heat and expelling damp, dispelling wind blood-nourishing, the work(of antibacterial desinsection, has to the fungal infection of the hand
Good therapeutic effect.
2nd, composition provided by the invention has the effect of notable to the fungal infection of the hand, and total effective rate is up to 88.6%..
3rd, Traditional Chinese medicine composition formula of the present invention is rationally innovated, and production cost is low, technique is simple.
Embodiment
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are to be used to illustrate
The present invention rather than limitation of the present invention.The present invention is belonged to according to the simple modifications that the essence of the present invention is carried out to the present invention
Claimed scope.Unless otherwise indicated, the percentage of the amount of alcohol in the present invention is percentage by volume, and v/v represents solution
Volume ratio.
The lotion of embodiment 1
Camphor tree oil 3kg, lemon are weighed by oily 3kg, Baeckea frutescens oil 1kg, MEIHUA BINGPIAN 1kg, tea-seed oil 0.5kg., stir evenly, add water to adjust
To 1000mL, stir evenly, stand 12h, refined filtration, packing, produce lotion of the present invention.
The granule of embodiment 2
Camphor tree oil 5kg, lemon are weighed by oily 5kg, Baeckea frutescens oil 3kg, MEIHUA BINGPIAN 3kg, tea-seed oil 2kg.Add auxiliary material dextrin, form sediment
Powder, mix, pelletized with ethanol in proper amount, whole grain after 60 DEG C of dryings, particle is made, produces.
The granule of embodiment 3
Camphor tree oil 3.5kg, lemon are weighed by oily 3.5kg, Baeckea frutescens oil 1.5kg, MEIHUA BINGPIAN 1.5kg, tea-seed oil 1kg.Add and form sediment
Powder, dextrin, granulation, dry, whole grain produce.
The liniment of embodiment 4
Camphor tree oil 4.5kg, lemon are weighed by oily 4.5kg, Baeckea frutescens oil 2.5kg, MEIHUA BINGPIAN 2.5kg, tea-seed oil 1.5kg.Add pure
Change 2 times that water ad pond om is medicinal material gross weight, add 0.1% sodium benzoate, 0.05% methyl hydroxybenzoate, mix, packing,
Produce liniment of the present invention.
The paste of embodiment 5
Camphor tree oil 4kg, lemon are weighed by oily 4kg, Baeckea frutescens oil 2kg, MEIHUA BINGPIAN 2kg, tea-seed oil 1.2kg.Mix, it is standby.
Stearic acid 15g is weighed, vaseline 100g, lanolin 80g, glyceryl stearate 35g, hexadecanol 80g, is heated to
85 DEG C, stir evenly, it is standby as oil phase;Separately take glycerine 130g, ethyl-para-hydroxybenzoate 2g, lauryl sodium sulfate 20g, the moon
Osmanthus Azone 25g, adds said mixture, and water use regulation makes oil, the common 1000g of water two-phase, as aqueous phase, is heated to 90 DEG C, treats
All after dissolving, constant temperature stirs evenly to 85 DEG C;Oil phase is slowly added into aqueous phase, puts in refiner and stirs, is cooled down, is solidified, packing,
Produce paste of the present invention.
The paste of embodiment 6
Camphor tree oil 3.8kg, lemon are weighed by oily 4.2kg, Baeckea frutescens oil 2.3kg, MEIHUA BINGPIAN 1.8kg, tea-seed oil 1.8kg.Mix,
It is standby.
Stearic acid 18g is weighed, vaseline 100g, lanolin 80g, glyceryl stearate 30g, hexadecanol 82g, is heated to
85 DEG C, stir evenly, it is standby as oil phase;Separately take glycerine 110g, ethyl-para-hydroxybenzoate 4g, lauryl sodium sulfate 30g, the moon
Osmanthus Azone 30g, adds said mixture, and water use regulation makes oil, the common 1000g of water two-phase, as aqueous phase, is heated to 90 DEG C, treats
All after dissolving, constant temperature stirs evenly to 85 DEG C;Oil phase is slowly added into aqueous phase, puts in refiner and stirs, is cooled down, is solidified, packing,
Produce paste of the present invention.
The application of embodiment 7
Camphor tree oil 4.2kg, lemon are weighed by oily 3.8kg, Baeckea frutescens oil 1.8kg, MEIHUA BINGPIAN 2.3kg, tea-seed oil 0.8kg.Mix,
Produce.
Embodiment 8
Application prepared by the embodiment of the present invention 7, fungal infection of the hand patient's external application is given, one time a day, clinical data is as follows:
Disorder class | Illness number of cases | The course of disease | Treatment time | Efficiently individual quantity | Total effective rate |
The fungal infection of the hand | 44 | - 3 years March | The 1-3 months | 39 | 88.6% |
Embodiment 9
Yuan XX, man, 46 years old.Main suit's both hands very itch unbearably, incrustation, take off white pachydermia.Personality is irritable, winter trick is not cold.Tongue side
Point is red, tongue is white.Examine as the fungal infection of the hand.Treated using the embodiment of the present invention 2, palm desquamation, dry itch start to mitigate after one week, 3 months
Palm returns to normal afterwards, does not itch, and does not peel.
Claims (4)
1. a kind of Chinese medicine composition for treating the fungal infection of the hand, it is characterised in that it is to include being prepared by the raw material of following parts by weight
's:Camphor tree oil 30-50 parts, lemon are by oily 30-50 parts, Baeckea frutescens oil 10-30 parts, MEIHUA BINGPIAN 10-30 parts, tea-seed oil 5-20 parts.
2. the Chinese medicine composition of the treatment fungal infection of the hand as claimed in claim 1, it is characterised in that it is by including following parts by weight
Raw material be prepared:Camphor tree oil 35-45 parts, lemon by oily 35-45 parts, Baeckea frutescens oil 15-25 parts, MEIHUA BINGPIAN 15-25 parts,
Tea-seed oil 10-15 parts.
3. the Chinese medicine composition of the treatment fungal infection of the hand as claimed in claim 1 or 2, it is characterised in that its active component is will be each
Raw material, which is mixed with, to be formed.
4. a kind of Chinese medicine composition for treating the fungal infection of the hand, as the treatment fungal infection of the hand described in claim 1 or 2 Chinese medicine composition with
Pharmaceutically acceptable carrier combination is prepared.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108578281A (en) * | 2018-05-08 | 2018-09-28 | 南京日光生物科技有限公司 | A kind of compound essential oil and preparation method thereof for turning joint nursing |
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CN1200270A (en) * | 1997-05-25 | 1998-12-02 | 邱国华 | Recipe and mfg. method for antifungal agent |
CN101199787A (en) * | 2007-12-06 | 2008-06-18 | 朱锋 | Medicament compound for treating skin disease |
CN101513433A (en) * | 2008-02-18 | 2009-08-26 | 唐远福 | External ointment for treating herpes zoster |
-
2017
- 2017-11-16 CN CN201711133544.5A patent/CN107837315A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN88101422A (en) * | 1988-03-20 | 1988-12-21 | 曲治国 | The manufacture method of treatment psoriasis drug |
CN1200270A (en) * | 1997-05-25 | 1998-12-02 | 邱国华 | Recipe and mfg. method for antifungal agent |
CN101199787A (en) * | 2007-12-06 | 2008-06-18 | 朱锋 | Medicament compound for treating skin disease |
CN101513433A (en) * | 2008-02-18 | 2009-08-26 | 唐远福 | External ointment for treating herpes zoster |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108578281A (en) * | 2018-05-08 | 2018-09-28 | 南京日光生物科技有限公司 | A kind of compound essential oil and preparation method thereof for turning joint nursing |
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Application publication date: 20180327 |