CA2293335A1 - 9-oxime erythromycin derivatives - Google Patents

9-oxime erythromycin derivatives Download PDF

Info

Publication number: CA2293335A1
Authority: CA; Canada
Prior art keywords: carbamate; methyl; deoxo; hydrazo; deoxy
Prior art date: 1997-06-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002293335A

Other languages

English (en)

French (fr)

Inventor

Yong-Jin Wu

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Products Inc

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-11

Filing date

1998-05-15

Publication date

1998-12-17

1998-05-15 Application filed by Individual filed Critical Individual

1998-12-17 Publication of CA2293335A1 publication Critical patent/CA2293335A1/en

Status Abandoned legal-status Critical Current

Links

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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Genetics & Genomics (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

CA002293335A 1997-06-11 1998-05-15 9-oxime erythromycin derivatives Abandoned CA2293335A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US4934997P	1997-06-11	1997-06-11
US60/049349		1997-06-11
PCT/IB1998/000741 WO1998056800A1 (en)	1997-06-11	1998-05-15	9-oxime erythromycin derivatives

Publications (1)

Publication Number	Publication Date
CA2293335A1 true CA2293335A1 (en)	1998-12-17

Family

ID=21959341

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002293335A Abandoned CA2293335A1 (en)	1997-06-11	1998-05-15	9-oxime erythromycin derivatives

Country Status (31)

Country	Link
EP (1)	EP0988308A1 (zh)
JP (1)	JP2000513026A (zh)
KR (1)	KR20010013660A (zh)
CN (1)	CN1259135A (zh)
AP (1)	AP9801253A0 (zh)
AR (1)	AR012244A1 (zh)
AU (1)	AU7226798A (zh)
BG (1)	BG103947A (zh)
BR (1)	BR9810021A (zh)
CA (1)	CA2293335A1 (zh)
CO (1)	CO4940506A1 (zh)
CZ (1)	CZ9904388A3 (zh)
EA (1)	EA199901016A1 (zh)
GT (1)	GT199800074A (zh)
HN (1)	HN1998000073A (zh)
HR (1)	HRP980316A2 (zh)
HU (1)	HUP0002252A3 (zh)
ID (1)	ID24529A (zh)
IL (1)	IL132767A0 (zh)
IS (1)	IS5251A (zh)
MA (1)	MA26505A1 (zh)
NO (1)	NO996108L (zh)
OA (1)	OA11225A (zh)
PA (1)	PA8451801A1 (zh)
PE (1)	PE79899A1 (zh)
PL (1)	PL337606A1 (zh)
TN (1)	TNSN98083A1 (zh)
TR (1)	TR199902995T2 (zh)
TW (1)	TW448174B (zh)
WO (1)	WO1998056800A1 (zh)
ZA (1)	ZA985018B (zh)

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AR043050A1 (es)	2002-09-26	2005-07-13	Rib X Pharmaceuticals Inc	Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
CA2529817C (en) *	2003-03-10	2013-02-12	Optimer Pharmaceuticals, Inc.	Novel antibacterial agents
CN102816194A (zh)	2004-02-27	2012-12-12	瑞伯-X医药品有限公司	大环化合物以及其制作和使用方法
JP5698979B2 (ja)	2007-10-25	2015-04-08	センプラファーマシューティカルズ，インコーポレイテッド	マクロライド系抗菌剤の調製プロセス
EP2365747B1 (en)	2008-10-24	2018-04-11	Cempra Pharmaceuticals, Inc.	Methods for treating gastrointestinal diseases
US9937194B1 (en)	2009-06-12	2018-04-10	Cempra Pharmaceuticals, Inc.	Compounds and methods for treating inflammatory diseases
EP2475253B1 (en)	2009-09-10	2016-10-26	Cempra Pharmaceuticals, Inc.	Methods for treating malaria, tuberculosis and mac diseases
CN102146085B (zh) *	2010-02-09	2014-03-26	北京理工大学	一种9-肟醚酮内酯衍生物、制备方法及其药物组合物
NZ602544A (en)	2010-03-22	2014-11-28	Cempra Pharmaceuticals Inc	Crystalline forms of a macrolide, and uses therefor
SI2571506T1 (sl)	2010-05-20	2017-12-29	Cempra Pharmaceuticals, Inc.	Postopki za pripravo makrolidov in ketolidov ter njihovih intermediatov
KR20180110181A (ko)	2010-09-10	2018-10-08	셈프라 파마슈티컬스, 인크.	질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
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1998
- 1998-05-15 JP JP11501928A patent/JP2000513026A/ja active Pending
- 1998-05-15 CN CN98805848A patent/CN1259135A/zh active Pending
- 1998-05-15 ID IDW991570A patent/ID24529A/id unknown
- 1998-05-15 EA EA199901016A patent/EA199901016A1/ru unknown
- 1998-05-15 WO PCT/IB1998/000741 patent/WO1998056800A1/en not_active Application Discontinuation
- 1998-05-15 CZ CZ19994388A patent/CZ9904388A3/cs unknown
- 1998-05-15 PL PL98337606A patent/PL337606A1/xx unknown
- 1998-05-15 TR TR1999/02995T patent/TR199902995T2/xx unknown
- 1998-05-15 BR BR9810021-1A patent/BR9810021A/pt not_active IP Right Cessation
- 1998-05-15 AU AU72267/98A patent/AU7226798A/en not_active Abandoned
- 1998-05-15 IL IL13276798A patent/IL132767A0/xx unknown
- 1998-05-15 KR KR1019997011672A patent/KR20010013660A/ko not_active Ceased
- 1998-05-15 CA CA002293335A patent/CA2293335A1/en not_active Abandoned
- 1998-05-15 HU HU0002252A patent/HUP0002252A3/hu unknown
- 1998-05-15 EP EP98919394A patent/EP0988308A1/en not_active Withdrawn
- 1998-05-19 HN HN1998000073A patent/HN1998000073A/es unknown
- 1998-05-21 PA PA19988451801A patent/PA8451801A1/es unknown
- 1998-06-04 AP APAP/P/1998/001253A patent/AP9801253A0/en unknown
- 1998-06-05 GT GT199800074A patent/GT199800074A/es unknown
- 1998-06-08 PE PE1998000470A patent/PE79899A1/es not_active Application Discontinuation
- 1998-06-08 TW TW087109086A patent/TW448174B/zh active
- 1998-06-09 AR ARP980102703A patent/AR012244A1/es unknown
- 1998-06-10 ZA ZA9805018A patent/ZA985018B/xx unknown
- 1998-06-10 MA MA25105A patent/MA26505A1/fr unknown
- 1998-06-10 TN TNTNSN98083A patent/TNSN98083A1/fr unknown
- 1998-06-11 HR HR60/049,349A patent/HRP980316A2/hr not_active Application Discontinuation
- 1998-06-11 CO CO98033538A patent/CO4940506A1/es unknown
1999
- 1999-11-16 IS IS5251A patent/IS5251A/is unknown
- 1999-12-03 BG BG103947A patent/BG103947A/xx unknown
- 1999-12-03 OA OA9900269A patent/OA11225A/en unknown
- 1999-12-10 NO NO996108A patent/NO996108L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
KR20010013660A (ko)	2001-02-26
CO4940506A1 (es)	2000-07-24
NO996108D0 (no)	1999-12-10
BR9810021A (pt)	2000-09-19
PL337606A1 (en)	2000-08-28
BG103947A (en)	2000-07-31
AR012244A1 (es)	2000-09-27
AU7226798A (en)	1998-12-30
EP0988308A1 (en)	2000-03-29
IL132767A0 (en)	2001-03-19
GT199800074A (es)	1999-11-27
HRP980316A2 (en)	1999-04-30
WO1998056800A1 (en)	1998-12-17
HUP0002252A3 (en)	2002-01-28
IS5251A (is)	1999-11-16
PA8451801A1 (es)	2000-05-24
NO996108L (no)	2000-02-10
MA26505A1 (fr)	2004-12-20
TW448174B (en)	2001-08-01
JP2000513026A (ja)	2000-10-03
PE79899A1 (es)	1999-08-25
CN1259135A (zh)	2000-07-05
EA199901016A1 (ru)	2000-06-26
TNSN98083A1 (fr)	2005-03-15
HUP0002252A2 (hu)	2000-12-28
ZA985018B (en)	1999-12-10
AP9801253A0 (en)	1999-12-04
ID24529A (id)	2000-07-20
OA11225A (en)	2003-07-17
TR199902995T2 (xx)	2000-02-21
CZ9904388A3 (cs)	2002-10-16
HN1998000073A (es)	1999-01-08

Publication	Publication Date	Title
EP0988310B1 (en)	2003-10-01	4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives
CA2293335A1 (en)	1998-12-17	9-oxime erythromycin derivatives
US6159945A (en)	2000-12-12	9-amino-3-keto erythromycin derivatives
CA2293397C (en)	2004-08-31	C-4''-substituted macrolide derivatives
EP1131331B1 (en)	2004-03-03	13-membered azalides and their use as antibiotic agents
EP0984019B1 (en)	2004-06-02	C11 carbamates of macrolide antibacterials
EP0992509B1 (en)	2004-09-22	Novel macrolide derivatives
US6162794A (en)	2000-12-19	Erythromycin derivatives
US6248719B1 (en)	2001-06-19	Tricyclic 3-keto derivatives of 6-O-methylerthromycin
US20020025937A1 (en)	2002-02-28	9-oxime erythromycin derivatives
US6498146B1 (en)	2002-12-24	Erythromycin derivatives
EP0952157B1 (en)	2003-06-18	9A, 11B-Dehydro derivatives of 9-oxime-3-keto-6-0-methylerythromycin
MXPA99011494A (en)	2000-07-01	9-oxime erythromycin derivatives
EP1437360A2 (en)	2004-07-14	C11 Carbamates of macrolide antibacterials
MXPA01005055A (en)	2001-12-04	13-membered azalides and their use as antibiotic agents
MXPA99011495A (en)	2001-05-17	4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives

Legal Events

Date	Code	Title	Description
1999-12-09	EEER	Examination request
2003-05-15	FZDE	Discontinued