OA11225A - 9-Oxime erythromycin derivatives - Google Patents

9-Oxime erythromycin derivatives Download PDF

Info

Publication number: OA11225A
Authority: OA; OAPI
Prior art keywords: carbamate; deoxo; deoxy; hydrazo; desosaminyl
Prior art date: 1997-06-11

Application number

OA9900269A

Other languages

English (en)

Inventor

Yong-Jin Wu

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-11

Filing date

1999-12-03

Publication date

2003-07-17

1999-12-03 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2003-07-17 Publication of OA11225A publication Critical patent/OA11225A/en

Links

0 CC[C@@]([C@@]1OC([n]2cncc2)=O)([C@]1(C)C=C(C)C([C@](C)C[C@@](C)([C@@]([C@@](C)C([C@]1C)=O)O[C@@]2O[C@](C)C[C@](*)[C@@]2OC(C)=O)OC)=O)OC1=O Chemical compound CC[C@@]([C@@]1OC([n]2cncc2)=O)([C@]1(C)C=C(C)C([C@](C)C[C@@](C)([C@@]([C@@](C)C([C@]1C)=O)O[C@@]2O[C@](C)C[C@](*)[C@@]2OC(C)=O)OC)=O)OC1=O 0.000 description 2

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Tropical Medicine & Parasitology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

OA9900269A 1997-06-11 1999-12-03 9-Oxime erythromycin derivatives OA11225A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US4934997P	1997-06-11	1997-06-11

Publications (1)

Publication Number	Publication Date
OA11225A true OA11225A (en)	2003-07-17

Family

ID=21959341

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA9900269A OA11225A (en)	1997-06-11	1999-12-03	9-Oxime erythromycin derivatives

Country Status (31)

Country	Link
EP (1)	EP0988308A1 (zh)
JP (1)	JP2000513026A (zh)
KR (1)	KR20010013660A (zh)
CN (1)	CN1259135A (zh)
AP (1)	AP9801253A0 (zh)
AR (1)	AR012244A1 (zh)
AU (1)	AU7226798A (zh)
BG (1)	BG103947A (zh)
BR (1)	BR9810021A (zh)
CA (1)	CA2293335A1 (zh)
CO (1)	CO4940506A1 (zh)
CZ (1)	CZ9904388A3 (zh)
EA (1)	EA199901016A1 (zh)
GT (1)	GT199800074A (zh)
HN (1)	HN1998000073A (zh)
HR (1)	HRP980316A2 (zh)
HU (1)	HUP0002252A3 (zh)
ID (1)	ID24529A (zh)
IL (1)	IL132767A0 (zh)
IS (1)	IS5251A (zh)
MA (1)	MA26505A1 (zh)
NO (1)	NO996108L (zh)
OA (1)	OA11225A (zh)
PA (1)	PA8451801A1 (zh)
PE (1)	PE79899A1 (zh)
PL (1)	PL337606A1 (zh)
TN (1)	TNSN98083A1 (zh)
TR (1)	TR199902995T2 (zh)
TW (1)	TW448174B (zh)
WO (1)	WO1998056800A1 (zh)
ZA (1)	ZA985018B (zh)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HN1998000159A (es) *	1997-10-29	1999-02-09	Monsanto Co	Derivados de 9- amino - 3 ceto eritromicina
AU5299499A (en) *	1998-09-22	2000-04-10	Pfizer Products Inc.	Carbamate and carbazate ketolide antibiotics
FR2786188B1 (fr) *	1998-11-24	2002-10-31	Hoechst Marion Roussel Inc	Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
US6258785B1 (en)	1998-12-02	2001-07-10	Pfizer Inc.	Crystalline 9-E-(O-methyl)oxime of 11, 12-dideoxy-3-de(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribohexopyranosyloxy)-6-O-methyl-12,11-(iminocarbonyl-(2-(3-(4-(3-pyridinyl)1H-imadazol-1-yl)propyl)hydrazono))-3-oxoerythromycin
EP1298138B1 (en) *	1998-12-10	2006-11-02	Pfizer Products Inc.	Carbamate and Carbazate Ketolide Antibiotics
US6284732B1 (en) *	1998-12-18	2001-09-04	Bio-Rad Laboratories, Inc.	Peptides and peptide analogues designed from HFE protein and their uses in the treatment of iron overload diseases
ES2272273T3 (es) *	1999-04-16	2007-05-01	Kosan Biosciences, Inc.	Agentes antiinfecciosos macrolidos.
CZ20013733A3 (cs)	1999-05-24	2002-11-13	Pfizer Products Inc.	Deriváty 13-methylerythromycinu
DE60005334T2 (de) *	1999-06-07	2004-06-24	Abbott Laboratories, Abbott Park	6-o-carbamat ketolide derivate
ID27331A (id) *	1999-09-29	2001-03-29	Pfizer Prod Inc	Pembuatan antibiotik-antibiotik ketolida karbamat
EP1114826A3 (en) *	1999-12-29	2001-10-31	Pfizer Products Inc.	Novel antibacterial and prokinetic macrolides
EP1439186A3 (en) *	1999-12-29	2004-11-03	Pfizer Products Inc.	Intermediates for novel antibacterial and prokinetic macrolides
US6946446B2 (en)	2000-02-24	2005-09-20	Abbott Laboratories	Anti-infective agents useful against multidrug-resistant strains of bacteria
US6403776B1 (en)	2000-07-05	2002-06-11	Pfizer Inc.	Synthesis of carbamate ketolide antibiotics
WO2003090761A1 (en) *	2002-04-25	2003-11-06	Abbott Laboratories	9-oxime macrolide antibacterials
US7091196B2 (en)	2002-09-26	2006-08-15	Rib-X Pharmaceuticals, Inc.	Bifunctional heterocyclic compounds and methods of making and using same
CA2529817C (en) *	2003-03-10	2013-02-12	Optimer Pharmaceuticals, Inc.	Novel antibacterial agents
JP5383037B2 (ja)	2004-02-27	2014-01-08	リブ−エックスファーマシューティカルズ，インコーポレイテッド	大環状化合物およびそれらを製造し使用する方法
CN101917850B (zh)	2007-10-25	2016-01-13	森普拉制药公司	大环内酯类抗菌剂的制备方法
CN102223794B (zh)	2008-10-24	2017-12-22	森普拉制药公司	使用含三唑的大环内酯治疗抗性疾病的方法
US9937194B1 (en)	2009-06-12	2018-04-10	Cempra Pharmaceuticals, Inc.	Compounds and methods for treating inflammatory diseases
JP5914335B2 (ja)	2009-09-10	2016-05-11	センプラファーマシューティカルズ，インコーポレイテッド	マラリア、結核、及びｍａｃ病の治療方法
CN102146085B (zh) *	2010-02-09	2014-03-26	北京理工大学	一种9-肟醚酮内酯衍生物、制备方法及其药物组合物
BR112012023950A2 (pt)	2010-03-22	2016-07-05	Cempra Pharmaceuticals Inc	formas cristalinas de um macrolídeo, e usos dos mesmos
ES2636948T3 (es)	2010-05-20	2017-10-10	Cempra Pharmaceuticals, Inc.	Procesos para preparar macrólidos y cetólidos e intermediarios para los mismos
EP2613630A4 (en)	2010-09-10	2014-01-15	Cempra Pharmaceuticals Inc	FLUOROCETOLIDES FORMING HYDROGEN LINKS TO TREAT DISEASES
RU2658050C2 (ru)	2012-03-27	2018-06-19	Семпра Фармасьютикалз, Инк.	Парентеральные составы для введения макролидных антибиотиков
WO2014152326A1 (en)	2013-03-14	2014-09-25	Cempra Pharmaceuticals, Inc.	Methods for treating respiratory diseases and formulations therefor
RU2015138797A (ru)	2013-03-15	2017-04-24	Семпра Фармасьютикалс, Инк.	Конвергентные способы получения макролидных антибактериальных агентов

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL114589A (en) *	1990-11-21	1999-12-22	Roussel Uclaf	Intermediates for the preparation of the history of erythromycin
US5527780A (en) *	1992-11-05	1996-06-18	Roussel Uclaf	Erythromycin derivatives
FR2718450B1 (fr) *	1994-04-08	1997-01-10	Roussel Uclaf	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

1998
- 1998-05-15 ID IDW991570A patent/ID24529A/id unknown
- 1998-05-15 CN CN98805848A patent/CN1259135A/zh active Pending
- 1998-05-15 AU AU72267/98A patent/AU7226798A/en not_active Abandoned
- 1998-05-15 JP JP11501928A patent/JP2000513026A/ja active Pending
- 1998-05-15 KR KR1019997011672A patent/KR20010013660A/ko not_active Application Discontinuation
- 1998-05-15 BR BR9810021-1A patent/BR9810021A/pt not_active IP Right Cessation
- 1998-05-15 PL PL98337606A patent/PL337606A1/xx unknown
- 1998-05-15 CA CA002293335A patent/CA2293335A1/en not_active Abandoned
- 1998-05-15 EA EA199901016A patent/EA199901016A1/ru unknown
- 1998-05-15 IL IL13276798A patent/IL132767A0/xx unknown
- 1998-05-15 CZ CZ19994388A patent/CZ9904388A3/cs unknown
- 1998-05-15 WO PCT/IB1998/000741 patent/WO1998056800A1/en not_active Application Discontinuation
- 1998-05-15 EP EP98919394A patent/EP0988308A1/en not_active Withdrawn
- 1998-05-15 TR TR1999/02995T patent/TR199902995T2/xx unknown
- 1998-05-15 HU HU0002252A patent/HUP0002252A3/hu unknown
- 1998-05-19 HN HN1998000073A patent/HN1998000073A/es unknown
- 1998-05-21 PA PA19988451801A patent/PA8451801A1/es unknown
- 1998-06-04 AP APAP/P/1998/001253A patent/AP9801253A0/en unknown
- 1998-06-05 GT GT199800074A patent/GT199800074A/es unknown
- 1998-06-08 PE PE1998000470A patent/PE79899A1/es not_active Application Discontinuation
- 1998-06-08 TW TW087109086A patent/TW448174B/zh active
- 1998-06-09 AR ARP980102703A patent/AR012244A1/es unknown
- 1998-06-10 ZA ZA9805018A patent/ZA985018B/xx unknown
- 1998-06-10 MA MA25105A patent/MA26505A1/fr unknown
- 1998-06-10 TN TNTNSN98083A patent/TNSN98083A1/fr unknown
- 1998-06-11 HR HR60/049,349A patent/HRP980316A2/hr not_active Application Discontinuation
- 1998-06-11 CO CO98033538A patent/CO4940506A1/es unknown
1999
- 1999-11-16 IS IS5251A patent/IS5251A/is unknown
- 1999-12-03 BG BG103947A patent/BG103947A/xx unknown
- 1999-12-03 OA OA9900269A patent/OA11225A/en unknown
- 1999-12-10 NO NO996108A patent/NO996108L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
GT199800074A (es)	1999-11-27
BR9810021A (pt)	2000-09-19
TNSN98083A1 (fr)	2005-03-15
TW448174B (en)	2001-08-01
CN1259135A (zh)	2000-07-05
EP0988308A1 (en)	2000-03-29
PL337606A1 (en)	2000-08-28
ZA985018B (en)	1999-12-10
EA199901016A1 (ru)	2000-06-26
NO996108L (no)	2000-02-10
AP9801253A0 (en)	1999-12-04
AR012244A1 (es)	2000-09-27
HN1998000073A (es)	1999-01-08
CO4940506A1 (es)	2000-07-24
WO1998056800A1 (en)	1998-12-17
ID24529A (id)	2000-07-20
PA8451801A1 (es)	2000-05-24
NO996108D0 (no)	1999-12-10
HUP0002252A2 (hu)	2000-12-28
HRP980316A2 (en)	1999-04-30
BG103947A (en)	2000-07-31
IL132767A0 (en)	2001-03-19
AU7226798A (en)	1998-12-30
JP2000513026A (ja)	2000-10-03
IS5251A (is)	1999-11-16
TR199902995T2 (xx)	2000-02-21
CZ9904388A3 (cs)	2002-10-16
MA26505A1 (fr)	2004-12-20
KR20010013660A (ko)	2001-02-26
CA2293335A1 (en)	1998-12-17
PE79899A1 (es)	1999-08-25
HUP0002252A3 (en)	2002-01-28

Publication	Publication Date	Title
OA11225A (en)	2003-07-17	9-Oxime erythromycin derivatives
EP0988310B1 (en)	2003-10-01	4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives
US6159945A (en)	2000-12-12	9-amino-3-keto erythromycin derivatives
EP1131331B1 (en)	2004-03-03	13-membered azalides and their use as antibiotic agents
EP0895999A1 (en)	1999-02-10	C-4" substituted macrolide antibiotics
SK9772000A3 (en)	2002-09-10	Erythromycin derivatives, methods for their producing and pharmaceutical compositions based thereon
US6291656B1 (en)	2001-09-18	Tricyclic erythromycin derivatives
US6262030B1 (en)	2001-07-17	Erythromycin derivatives
US6583274B1 (en)	2003-06-24	Crystalline forms of macrolide antibiotic
US6162794A (en)	2000-12-19	Erythromycin derivatives
US6248719B1 (en)	2001-06-19	Tricyclic 3-keto derivatives of 6-O-methylerthromycin
US20020025937A1 (en)	2002-02-28	9-oxime erythromycin derivatives
US6498146B1 (en)	2002-12-24	Erythromycin derivatives
US20020077302A1 (en)	2002-06-20	Tricyclic erythromycin derivatives
US6258785B1 (en)	2001-07-10	Crystalline 9-E-(O-methyl)oxime of 11, 12-dideoxy-3-de(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribohexopyranosyloxy)-6-O-methyl-12,11-(iminocarbonyl-(2-(3-(4-(3-pyridinyl)1H-imadazol-1-yl)propyl)hydrazono))-3-oxoerythromycin
EP0952157B1 (en)	2003-06-18	9A, 11B-Dehydro derivatives of 9-oxime-3-keto-6-0-methylerythromycin
NZ526120A (en)	2005-02-25	13-membered azalides and their use as antibiotic agents
MXPA99011494A (en)	2000-07-01	9-oxime erythromycin derivatives
MXPA01005055A (en)	2001-12-04	13-membered azalides and their use as antibiotic agents