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BRPI0720625A2 - Derivados de indol de 4,5-anel anulados e métodos de uso dos mesmos - Google Patents

Derivados de indol de 4,5-anel anulados e métodos de uso dos mesmos

Info

Publication number
BRPI0720625A2
BRPI0720625A2 BRPI0720625-9A2A BRPI0720625A BRPI0720625A2 BR PI0720625 A2 BRPI0720625 A2 BR PI0720625A2 BR PI0720625 A BRPI0720625 A BR PI0720625A BR PI0720625 A2 BRPI0720625 A2 BR PI0720625A2
Authority
BR
Brazil
Prior art keywords
ring
methods
indol derivatives
indol
derivatives
Prior art date
Application number
BRPI0720625-9A2A
Other languages
English (en)
Inventor
Kevin X Chen
Srikanth Venkatraman
F George Njoroge
Stuart B Rosenblum
Charles A Lesburg
Jose S Duca
Neng-Yang Shih
Francisco Velazquez
Gopinadhan N Anilkumar
Qingbei Zeng
Joseph A Kozlowski
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39186835&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0720625(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of BRPI0720625A2 publication Critical patent/BRPI0720625A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BRPI0720625-9A2A 2006-12-22 2007-12-17 Derivados de indol de 4,5-anel anulados e métodos de uso dos mesmos BRPI0720625A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87687706P 2006-12-22 2006-12-22
PCT/US2007/025754 WO2008082484A1 (en) 2006-12-22 2007-12-17 4,5-ring annulated indole derivatives for treating or preventing of hcv and related viral infections

Publications (1)

Publication Number Publication Date
BRPI0720625A2 true BRPI0720625A2 (pt) 2014-03-25

Family

ID=39186835

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0720625-9A2A BRPI0720625A2 (pt) 2006-12-22 2007-12-17 Derivados de indol de 4,5-anel anulados e métodos de uso dos mesmos

Country Status (18)

Country Link
US (1) US8557848B2 (pt)
EP (1) EP2064180B1 (pt)
JP (1) JP5079818B2 (pt)
KR (1) KR20090094154A (pt)
CN (1) CN101631773A (pt)
AR (1) AR064428A1 (pt)
AU (1) AU2007339382B2 (pt)
BR (1) BRPI0720625A2 (pt)
CA (1) CA2673249C (pt)
CL (1) CL2007003686A1 (pt)
CO (1) CO6190515A2 (pt)
EC (1) ECSP099447A (pt)
MX (1) MX2009006880A (pt)
NO (1) NO20092742L (pt)
PE (1) PE20081608A1 (pt)
RU (1) RU2009127855A (pt)
TW (1) TW200831496A (pt)
WO (1) WO2008082484A1 (pt)

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AU2007339382B2 (en) 2013-05-02
ECSP099447A (es) 2009-07-31
PE20081608A1 (es) 2008-11-12
CO6190515A2 (es) 2010-08-19
RU2009127855A (ru) 2011-01-27
TW200831496A (en) 2008-08-01
EP2064180B1 (en) 2016-07-13
CL2007003686A1 (es) 2008-06-27
KR20090094154A (ko) 2009-09-03
JP5079818B2 (ja) 2012-11-21
US8557848B2 (en) 2013-10-15
WO2008082484A1 (en) 2008-07-10
NO20092742L (no) 2009-09-21
EP2064180A1 (en) 2009-06-03
AR064428A1 (es) 2009-04-01
US20100098661A1 (en) 2010-04-22
JP2010513490A (ja) 2010-04-30
CA2673249A1 (en) 2008-07-10
CA2673249C (en) 2013-04-30
MX2009006880A (es) 2009-07-03
AU2007339382A1 (en) 2008-07-10
CN101631773A (zh) 2010-01-20

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