[go: up one dir, main page]

BRPI1016266A2 - compostos antivirais heterocíclicos - Google Patents

compostos antivirais heterocíclicos

Info

Publication number
BRPI1016266A2
BRPI1016266A2 BRPI1016266A BRPI1016266A BRPI1016266A2 BR PI1016266 A2 BRPI1016266 A2 BR PI1016266A2 BR PI1016266 A BRPI1016266 A BR PI1016266A BR PI1016266 A BRPI1016266 A BR PI1016266A BR PI1016266 A2 BRPI1016266 A2 BR PI1016266A2
Authority
BR
Brazil
Prior art keywords
antiviral compounds
heterocyclic antiviral
heterocyclic
compounds
antiviral
Prior art date
Application number
BRPI1016266A
Other languages
English (en)
Inventor
Sui-Ting Lui Alfred
Xavier Talamas Francisco
Li Jim
C Abbot Sarah
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BRPI1016266A2 publication Critical patent/BRPI1016266A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4433Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI1016266A 2009-03-06 2010-03-03 compostos antivirais heterocíclicos BRPI1016266A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15820709P 2009-03-06 2009-03-06
PCT/EP2010/052661 WO2010100178A1 (en) 2009-03-06 2010-03-03 Heterocyclic antiviral compounds

Publications (1)

Publication Number Publication Date
BRPI1016266A2 true BRPI1016266A2 (pt) 2019-09-24

Family

ID=42102526

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1016266A BRPI1016266A2 (pt) 2009-03-06 2010-03-03 compostos antivirais heterocíclicos

Country Status (14)

Country Link
US (1) US8168792B2 (pt)
EP (1) EP2403844A1 (pt)
JP (1) JP2012519661A (pt)
KR (1) KR20110122874A (pt)
CN (1) CN102341382A (pt)
AR (1) AR075718A1 (pt)
AU (1) AU2010220374A1 (pt)
BR (1) BRPI1016266A2 (pt)
CA (1) CA2752443A1 (pt)
IL (1) IL214288A0 (pt)
MX (1) MX2011008641A (pt)
SG (1) SG174252A1 (pt)
TW (1) TW201035083A (pt)
WO (1) WO2010100178A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007345526B2 (en) 2007-02-01 2013-02-28 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular diseases
WO2010079431A2 (en) 2009-01-08 2010-07-15 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
US10752611B2 (en) 2009-02-27 2020-08-25 Enanta Pharmaceuticals, Inc. Benzimidazole derivatives
AU2010224523B2 (en) 2009-03-18 2014-05-08 Resverlogix Corp. Novel anti-inflammatory agents
MX374414B (es) 2009-04-22 2025-03-06 Resverlogix Corp Nuevos agentes anti-inflamatorios.
US8734777B2 (en) * 2010-08-13 2014-05-27 Roche Palo Alto Llc Heterocyclic antiviral compounds
LT2773354T (lt) 2011-11-01 2019-08-12 Resverlogix Corp. Geriamosios greitai atsipalaiduojančios pakeistų chinozolinų vaisto formos
DK2822656T3 (en) 2012-03-07 2017-01-30 Inst Of Cancer Research: Royal Cancer Hospital (The) 3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
US9271978B2 (en) 2012-12-21 2016-03-01 Zenith Epigenetics Corp. Heterocyclic compounds as bromodomain inhibitors
WO2015017382A1 (en) * 2013-07-29 2015-02-05 Enanta Pharmaceuticals, Inc. Hepatitis c virus inhibitors
EP3044221B1 (en) 2013-09-11 2018-02-21 Institute of Cancer Research: Royal Cancer Hospital (The) 3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use
CN107530356A (zh) 2015-03-13 2018-01-02 雷斯韦洛吉克斯公司 用于治疗补体相关疾病之组合物及治疗方法
CN106810557B (zh) * 2015-11-27 2021-05-04 南京圣和药物研发有限公司 杂环化合物及其应用

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323180B1 (en) 1998-08-10 2001-11-27 Boehringer Ingelheim (Canada) Ltd Hepatitis C inhibitor tri-peptides
WO2001047833A1 (en) 1999-12-24 2001-07-05 Asahi Glass Company, Limited Silicon nitride filter and method of manufacture thereof
EP1292310A1 (en) 2000-05-10 2003-03-19 SmithKline Beecham Corporation Novel anti-infectives
US6448281B1 (en) 2000-07-06 2002-09-10 Boehringer Ingelheim (Canada) Ltd. Viral polymerase inhibitors
AR036081A1 (es) 2001-06-07 2004-08-11 Smithkline Beecham Corp Compuesto de 1,2-dihidroquinolina, su uso para preparar una composicion farmaceutica, metodos para prepararlo y compuestos del acido 2-aminobenzoico n-alquilado de utilidad como intermediarios en dichos metodos
AR035543A1 (es) 2001-06-26 2004-06-16 Japan Tobacco Inc Agente terapeutico para la hepatitis c que comprende un compuesto de anillo condensado, compuesto de anillo condensado, composicion farmaceutica que lo comprende, compuestos de benzimidazol, tiazol y bifenilo utiles como intermediarios para producir dichos compuestos, uso del compuesto de anillo con
WO2003007945A1 (en) 2001-07-20 2003-01-30 Boehringer Ingelheim (Canada) Ltd. Viral polymerase inhibitors
US6899700B2 (en) 2001-08-29 2005-05-31 Kimberly-Clark Worldwide, Inc. Therapeutic agent delivery tampon
AU2002359320A1 (en) 2001-10-29 2003-05-12 Smithkline Beecham Corporation Novel anit-infectives
WO2003059356A2 (en) 2001-10-30 2003-07-24 Smithkline Beecham Corporation Novel anti-infectives
AU2003248566A1 (en) 2002-05-24 2003-12-12 Smithkline Beecham Corporation Novel anti-infectives
ATE493408T1 (de) * 2002-11-01 2011-01-15 Abbott Lab Antiinfektiöse mittel
US20040097492A1 (en) 2002-11-01 2004-05-20 Pratt John K Anti-infective agents
BR0315897A (pt) * 2002-11-01 2008-05-13 Abbott Lab agentes antiinfecciosos
TWI332507B (en) 2002-11-19 2010-11-01 Hoffmann La Roche Antiviral nucleoside derivatives
WO2004052313A2 (en) 2002-12-11 2004-06-24 Smithkline Beecham Corporation Anti-infectives
AU2003300956A1 (en) 2002-12-11 2004-06-30 Smithkline Beecham Corporation Anti-infectives
AU2003297235A1 (en) 2002-12-17 2004-07-22 Smithkline Beecham Corporation Anti-infectives
WO2005019191A2 (en) 2003-08-25 2005-03-03 Abbott Laboratories 1, 1-dioxido-4h-1,2,4-benzothiadiazine derivate und verwandte verbindungen als inhibitoren der hcv polymerase zur behandlung von hepatitis c
AU2005276648A1 (en) 2004-08-23 2006-03-02 F. Hoffmann-La Roche Ag Heterocyclic antiviral compounds
US20070163927A1 (en) 2006-01-05 2007-07-19 M-I L.L.C. Vapor extracting and separator cleaning apparatus
KR20090094154A (ko) * 2006-12-22 2009-09-03 쉐링 코포레이션 Hcv 및 관련 바이러스 감염을 치료 또는 예방하기 위한 4,5-환 환상 인돌 유도체
HRP20110632T1 (hr) 2007-09-17 2011-10-31 Abbott Laboratories N-fenil-diokso-hidropirimidini korisni kao inhibitori virusa hepatitisa c (hcv)
JP2011528686A (ja) * 2008-07-23 2011-11-24 エフ.ホフマン−ラ ロシュ アーゲー ヘテロ環式抗ウイルス性化合物
RU2015144653A (ru) 2009-03-25 2018-12-29 Эббви Инк. Противовирусные соединения и их применения
CN102448952B (zh) 2009-03-25 2014-10-29 Abbvie公司 抗病毒化合物和其用途
AR077004A1 (es) * 2009-06-09 2011-07-27 Hoffmann La Roche Compuestos heterociclicos antivirales

Also Published As

Publication number Publication date
US8168792B2 (en) 2012-05-01
CA2752443A1 (en) 2010-09-10
EP2403844A1 (en) 2012-01-11
US20100226879A1 (en) 2010-09-09
JP2012519661A (ja) 2012-08-30
CN102341382A (zh) 2012-02-01
WO2010100178A1 (en) 2010-09-10
AR075718A1 (es) 2011-04-20
AU2010220374A1 (en) 2011-09-01
KR20110122874A (ko) 2011-11-11
IL214288A0 (en) 2011-09-27
MX2011008641A (es) 2011-09-06
SG174252A1 (en) 2011-10-28
TW201035083A (en) 2010-10-01

Similar Documents

Publication Publication Date Title
SMT201600351B (it) Composti antivirali
BR112012005616A2 (pt) compostos antivirais heterocíclicos
BRPI1010852A2 (pt) compostos antivirais heterocíclicos
BRPI0916233A2 (pt) compostos heterocíclicos antivirais
SMT201600008B (it) Composti di piridazinone
BRPI1016266A2 (pt) compostos antivirais heterocíclicos
ATE539070T1 (de) Heterozyklische antivirale verbindungen
DK2427449T3 (da) Vinylindazolylforbindelser
BR112012006859A2 (pt) compostos
ECSP12011999A (es) Derivados benzamida sustituidos
BRPI1013246A2 (pt) derivados de benzofuralina
BRPI1013614A2 (pt) compostos substituídos de espiro-amida
BR112012002828A2 (pt) derivados de 5-fluorpirimidinona
BRPI0924121A2 (pt) compostos antivirais heterocíclicos
DK2540728T3 (da) Heterocyklisk forbindelse
BRPI1005525A2 (pt) compostos de azaazuleno
DK2397480T3 (da) Diazepindionderivat
BRPI0821349A2 (pt) compostos antivirais heterocíclicos
BRPI0906705A2 (pt) Composto heterocíclicos
BRPI1013844A2 (pt) derivados de piridina-isoxazol
BRPI1013493A2 (pt) composto de pirimidina
BRPI1014454A2 (pt) derivados de isoxazol-pirazol
DK2387580T3 (da) Deoxyactagardinderivater
HRP20150932T1 (xx) Heterocikliäśki spojevi
BR112013010643A2 (pt) compostos heterocíclicos

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.