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ATE242267T1 - Extendin-4 konjugate und ihre medizinische verwendung - Google Patents

Extendin-4 konjugate und ihre medizinische verwendung

Info

Publication number
ATE242267T1
ATE242267T1 AT00945656T AT00945656T ATE242267T1 AT E242267 T1 ATE242267 T1 AT E242267T1 AT 00945656 T AT00945656 T AT 00945656T AT 00945656 T AT00945656 T AT 00945656T AT E242267 T1 ATE242267 T1 AT E242267T1
Authority
AT
Austria
Prior art keywords
conjugates
extendin
medical uses
useful
treatment
Prior art date
Application number
AT00945656T
Other languages
English (en)
Inventor
Bjarne Due Larsen
Jens Damsgaard Mikkelsen
Soren Neve
Original Assignee
Zealand Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zealand Pharma As filed Critical Zealand Pharma As
Application granted granted Critical
Publication of ATE242267T1 publication Critical patent/ATE242267T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AT00945656T 1999-07-12 2000-07-12 Extendin-4 konjugate und ihre medizinische verwendung ATE242267T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14359199P 1999-07-12 1999-07-12
EP99610043A EP1076066A1 (de) 1999-07-12 1999-08-09 Peptide zur Senkung des Blutglukosespiegels
PCT/DK2000/000393 WO2001004156A1 (en) 1999-07-12 2000-07-12 Peptides that lower blood glucose levels

Publications (1)

Publication Number Publication Date
ATE242267T1 true ATE242267T1 (de) 2003-06-15

Family

ID=26153727

Family Applications (2)

Application Number Title Priority Date Filing Date
AT00945656T ATE242267T1 (de) 1999-07-12 2000-07-12 Extendin-4 konjugate und ihre medizinische verwendung
AT03005786T ATE551362T1 (de) 1999-07-12 2000-07-12 Peptide, die den blutzuckergehalt senken

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT03005786T ATE551362T1 (de) 1999-07-12 2000-07-12 Peptide, die den blutzuckergehalt senken

Country Status (20)

Country Link
US (1) US20070111940A1 (de)
EP (4) EP1076066A1 (de)
JP (4) JP4332314B2 (de)
CN (1) CN1229390C (de)
AT (2) ATE242267T1 (de)
AU (2) AU781338B2 (de)
BE (1) BE2013C033I2 (de)
CA (2) CA2378431C (de)
CY (2) CY1113347T1 (de)
DE (1) DE60003182T2 (de)
DK (3) DK1329458T5 (de)
ES (3) ES2200892T3 (de)
FR (1) FR13C0021I2 (de)
HK (2) HK1058046A1 (de)
IL (4) IL147293A0 (de)
LU (1) LU92175I2 (de)
NZ (1) NZ517012A (de)
PT (3) PT1196444E (de)
SI (2) SI2112161T1 (de)
WO (1) WO2001004156A1 (de)

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CA2680437A1 (en) 2001-01-18
PT1196444E (pt) 2003-10-31
DE60003182T2 (de) 2004-05-06
JP2014169296A (ja) 2014-09-18
IL206445A (en) 2011-09-27
JP5553742B2 (ja) 2014-07-16
IL147293A (en) 2007-12-03
EP2112161A2 (de) 2009-10-28
EP1329458A2 (de) 2003-07-23
IL147293A0 (en) 2002-08-14
ATE551362T1 (de) 2012-04-15
EP1196444A1 (de) 2002-04-17
CA2378431A1 (en) 2001-01-18
DK1329458T5 (da) 2013-02-11
DK1196444T3 (da) 2003-09-29
CY2013032I1 (el) 2015-11-04
IL206445A0 (en) 2011-07-31
JP2003505347A (ja) 2003-02-12
LU92175I2 (fr) 2013-05-27
SI2112161T1 (sl) 2015-02-27
ES2384963T9 (es) 2012-10-16
PT1329458E (pt) 2012-07-03
CN1376166A (zh) 2002-10-23
NZ517012A (en) 2003-02-28
EP1196444B1 (de) 2003-06-04
FR13C0021I1 (de) 2013-05-03
HK1058046A1 (en) 2004-04-30
ES2384963T3 (es) 2012-07-16
BE2013C033I2 (de) 2019-10-16
EP2112161A3 (de) 2010-04-28
EP1196444B8 (de) 2003-08-06
EP2112161B1 (de) 2014-11-05
CA2378431C (en) 2010-02-09
PT2112161E (pt) 2015-02-10
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DK1329458T3 (da) 2012-07-16
AU781338B2 (en) 2005-05-19
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EP1329458B1 (de) 2012-03-28
FR13C0021I2 (fr) 2013-08-16
DE60003182D1 (de) 2003-07-10
HK1135119A1 (en) 2010-05-28
JP2011102305A (ja) 2011-05-26
WO2001004156A1 (en) 2001-01-18
AU5966000A (en) 2001-01-30
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DK2112161T3 (en) 2015-01-19
ES2529578T3 (es) 2015-02-23
IL185763A (en) 2012-04-30
CN1229390C (zh) 2005-11-30
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SI1329458T1 (sl) 2012-07-31
AU2005203735A1 (en) 2005-09-29
EP1076066A1 (de) 2001-02-14
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