SK18412001A3 - Spôsob prípravy citalopramu a antidepresívny farmaceutický prostriedok vyrobený týmto spôsobom - Google Patents

Spôsob prípravy citalopramu a antidepresívny farmaceutický prostriedok vyrobený týmto spôsobom Download PDF

Info

Publication number: SK18412001A3
Authority: SK; Slovakia
Prior art keywords: citalopram; process according; compound; nickel; formula
Prior art date: 1999-06-25

Application number

SK1841-2001A

Other languages

English (en)

Slovak (sk)

Inventor

Hans Petersen

Michael Harold Rock

Original Assignee

H. Lundbeck A/S

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-25

Filing date

1999-11-19

Publication date

2002-05-09

1999-11-19 Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S

2002-05-09 Publication of SK18412001A3 publication Critical patent/SK18412001A3/sk

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/22—Organic complexes
- B01J31/2282—Unsaturated compounds used as ligands
- B01J31/2295—Cyclic compounds, e.g. cyclopentadienyls
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
- B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/40—Substitution reactions at carbon centres, e.g. C-C or C-X, i.e. carbon-hetero atom, cross-coupling, C-H activation or ring-opening reactions
- B01J2231/42—Catalytic cross-coupling, i.e. connection of previously not connected C-atoms or C- and X-atoms without rearrangement
- B01J2231/4205—C-C cross-coupling, e.g. metal catalyzed or Friedel-Crafts type
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/84—Metals of the iron group
- B01J2531/847—Nickel

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Inorganic Chemistry (AREA)
Materials Engineering (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Furan Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)

SK1841-2001A 1999-06-25 1999-11-19 Spôsob prípravy citalopramu a antidepresívny farmaceutický prostriedok vyrobený týmto spôsobom SK18412001A3 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA199900921		1999-06-25
PCT/DK1999/000643 WO2000011926A2 (en)	1999-06-25	1999-11-19	Method for the preparation of citalopram

Publications (1)

Publication Number	Publication Date
SK18412001A3 true SK18412001A3 (sk)	2002-05-09

Family

ID=8099044

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1841-2001A SK18412001A3 (sk)	1999-06-25	1999-11-19	Spôsob prípravy citalopramu a antidepresívny farmaceutický prostriedok vyrobený týmto spôsobom

Country Status (36)

Country	Link
US (1)	US6750358B2 (pt)
EP (1)	EP1105382B1 (pt)
JP (1)	JP3389571B2 (pt)
KR (1)	KR100491369B1 (pt)
CN (1)	CN1129593C (pt)
AR (1)	AR020573A1 (pt)
AT (3)	ATE213237T1 (pt)
AU (2)	AU2001100433B4 (pt)
BG (1)	BG106190A (pt)
BR (1)	BR9917367A (pt)
CA (1)	CA2290125C (pt)
CH (1)	CH691304A5 (pt)
CZ (1)	CZ292174B6 (pt)
DE (2)	DE19983486C2 (pt)
DK (1)	DK1105382T3 (pt)
EA (1)	EA002661B1 (pt)
ES (1)	ES2172356T3 (pt)
FI (1)	FI108538B (pt)
GB (1)	GB2354240B (pt)
HK (1)	HK1047745B (pt)
HU (1)	HUP0103417A3 (pt)
IL (1)	IL145960A0 (pt)
IS (1)	IS5862A (pt)
IT (1)	ITMI991579A1 (pt)
MX (1)	MXPA01010986A (pt)
NO (1)	NO20010318L (pt)
NZ (1)	NZ514982A (pt)
PL (1)	PL345971A1 (pt)
PT (1)	PT1105382E (pt)
SE (1)	SE516689C2 (pt)
SI (1)	SI1105382T1 (pt)
SK (1)	SK18412001A3 (pt)
TR (1)	TR200103700T2 (pt)
UA (1)	UA62023C2 (pt)
WO (1)	WO2000011926A2 (pt)
ZA (1)	ZA200108855B (pt)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SK285530B6 (sk)	1998-12-23	2007-03-01	H. Lundbeck A/S	Spôsob prípravy 5-kyanoftalidu
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
CA2291129C (en)	1999-04-14	2002-10-22	H. Lundbeck A/S	Method for the preparation of citalopram
ITMI991581A1 (it) *	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
DE19983836C1 (de)	1999-10-25	2003-10-23	Lundbeck As Valby H	Verfahren zur Herstellung von Citalopram, 4-[1-(4- Fluorphenyl)-methanoyl]-benzonitril-Derivate und Verfahren zu deren Herstellung und deren Verwendung
TR200101874T1 (tr)	1999-10-25	2002-02-21	H. Lundbeck A/S	Sitalopram hazırlanması için yöntem
AR026063A1 (es)	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
CA2395404A1 (en)	1999-12-28	2001-07-05	H. Lundbeck A/S	Method for the preparation of citalopram
DK1246813T3 (da)	1999-12-30	2004-03-01	Lundbeck & Co As H	Fremgangsmåde til fremstilling af Citalopram
HUP0300343A2 (hu)	2000-01-14	2003-06-28	H. Lundbeck A/S	Eljárás 5-cianoftalid előállítására
FR2805812A1 (fr)	2000-02-24	2001-09-07	Lundbeck & Co As H	Procede de preparation du citalopram
NL1017417C1 (nl)	2000-03-03	2001-03-16	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
KR20020080481A (ko)	2000-03-13	2002-10-23	하. 룬트벡 아크티에 셀스카브	시탈로프람의 제조 방법
GB2357762B (en) *	2000-03-13	2002-01-30	Lundbeck & Co As H	Crystalline base of citalopram
JP2003527385A (ja)	2000-03-13	2003-09-16	ハー・ルンドベック・アクチエゼルスカベット	５−置換された１−（４−フルオロフェニル）−１，３−ジヒドロイソベンゾフランの段階的アルキル化法
IES20010206A2 (en)	2000-03-13	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
AU2001239213A1 (en)	2000-03-14	2001-09-24	H Lundbeck A/S	Method for the preparation of citalopram
AT5093U1 (de) *	2000-03-16	2002-03-25	Lundbeck & Co As H	Verfahren zur herstellung von
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
SK3362002A3 (en) *	2000-07-06	2002-08-06	Lundbeck & Co As H	Method for the preparation of citalopram
FI20011622L (fi) *	2000-08-18	2002-02-19	Lundbeck & Co As H	Menetelmä sitalopraamin valmistamiseksi
BR0106272A (pt) *	2000-12-22	2004-06-15	Lundbeck & Co As H	Processo para preparação de citalopram puro
DK1181272T3 (da) *	2000-12-28	2002-12-30	Lundbeck & Co As H	Fremgangsmåde til fremstilling af rent citalopram
WO2002060886A1 (en)	2001-01-30	2002-08-08	Orion Corporation, Fermion	Process for the preparation of 1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
RU2003130073A (ru) *	2001-03-09	2005-04-10	Ранбакси Лабораторис Лимитед (In)	Способ получения циталопрама
DE60217932T2 (de)	2001-07-31	2007-08-30	H. Lundbeck A/S, Valby	Kristalline Zusammensetzung enthaltend Escitalopram
AU2003222435A1 (en)	2002-01-07	2003-07-24	Sun Pharmaceutical Industries Limited	Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
PE20040991A1 (es)	2002-08-12	2004-12-27	Lundbeck & Co As H	Separacion de intermediarios para la preparacion de escitalopram
AU2003223105A1 (en) *	2003-03-24	2004-10-18	Hetero Drugs Limited	Novel crystalline forms of (s)-citalopram oxalate
US7019153B2 (en)	2003-06-10	2006-03-28	Sun Pharmaceutical Industries Limited	Process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran acetamido-3-substituted-3-cephem-4-carboxylic acid
TWI339651B (en)	2004-02-12	2011-04-01	Lundbeck & Co As H	Method for the separation of intermediates which may be used for the preparation of escitalopram
JP2006008603A (ja) *	2004-06-25	2006-01-12	Sumitomo Chemical Co Ltd	光学活性シタロプラムの製造方法、その中間体およびその製造方法
EP2141156A1 (en)	2004-08-23	2010-01-06	Sun Pharma Global FZE	Process for Preparation of Citalopram and Enantiomers
WO2006103550A1 (en) *	2005-03-31	2006-10-05	Ranbaxy Laboratories Limited	Processes for the preparation of citalopram and its intermediate 5-aminophthalide
US7834201B2 (en)	2005-06-22	2010-11-16	H. Lundbeck A/S	Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
TWI347942B (en)	2005-06-22	2011-09-01	Lundbeck & Co As H	Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
EP2017271A1 (en)	2007-07-06	2009-01-21	Aurobindo Pharma Limited	Process for the preparation of escitalopram

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1143702A (pt)	1965-03-18
GB1526331A (en) *	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8419963D0 (en)	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en)	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
CA2010159A1 (en)	1989-02-21	1990-08-21	James J. Maul	Cyanation of haloaromatics utilizing catalysts generated in situ starting with nic1 or nic1 6h 0
US5296507A (en)	1990-09-06	1994-03-22	H.Lundbeck A/S	Treatment of cerbrovascular disorders
DE19626659A1 (de)	1996-07-03	1998-01-08	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de)	1996-07-10	1998-01-15	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19706648A1 (de)	1997-02-20	1998-08-27	Bayer Ag	Verfahren zur Herstellung von aromatischen Nitrilen
ES2148120T3 (es)	1997-07-08	2002-01-16	Lundbeck & Co As H	Metodo para la preparacion de citalopram.
UA62985C2 (en)	1997-11-10	2004-01-15	Lunnbeck As H	A method for the preparation of citalopram
TR200001341T2 (tr)	1997-11-11	2000-11-21	H. Lundbeck A/S	Sitalopramın hazırlandığı metot
JP3892667B2 (ja)	1998-10-20	2007-03-14	ハー・ルンドベック・アクチエゼルスカベット	シタロプラムの製造方法
SK285530B6 (sk)	1998-12-23	2007-03-01	H. Lundbeck A/S	Spôsob prípravy 5-kyanoftalidu
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
US6331628B1 (en)	1999-03-29	2001-12-18	Nissan Chemical Industries, Ltd.	Process for the preparation of benzonitrile compounds
CA2291129C (en)	1999-04-14	2002-10-22	H. Lundbeck A/S	Method for the preparation of citalopram
ITMI991581A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
TR200101874T1 (tr)	1999-10-25	2002-02-21	H. Lundbeck A/S	Sitalopram hazırlanması için yöntem
US6310222B1 (en)	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
BR0106272A (pt)	2000-12-22	2004-06-15	Lundbeck & Co As H	Processo para preparação de citalopram puro
DK1181272T3 (da)	2000-12-28	2002-12-30	Lundbeck & Co As H	Fremgangsmåde til fremstilling af rent citalopram

1999
- 1999-07-15 IT IT1999MI001579A patent/ITMI991579A1/it unknown
- 1999-11-19 JP JP2000567065A patent/JP3389571B2/ja not_active Expired - Fee Related
- 1999-11-19 DK DK99968206T patent/DK1105382T3/da active
- 1999-11-19 MX MXPA01010986A patent/MXPA01010986A/es not_active IP Right Cessation
- 1999-11-19 AU AU2001100433A patent/AU2001100433B4/en not_active Ceased
- 1999-11-19 SK SK1841-2001A patent/SK18412001A3/sk unknown
- 1999-11-19 IL IL14596099A patent/IL145960A0/xx unknown
- 1999-11-19 NZ NZ514982A patent/NZ514982A/xx unknown
- 1999-11-19 PT PT99968206T patent/PT1105382E/pt unknown
- 1999-11-19 PL PL99345971A patent/PL345971A1/xx not_active Application Discontinuation
- 1999-11-19 KR KR10-2001-7013971A patent/KR100491369B1/ko not_active Expired - Fee Related
- 1999-11-19 AU AU13748/00A patent/AU1374800A/en active Pending
- 1999-11-19 CN CN99816768A patent/CN1129593C/zh not_active Expired - Fee Related
- 1999-11-19 EA EA200101071A patent/EA002661B1/ru not_active IP Right Cessation
- 1999-11-19 CH CH00307/01A patent/CH691304A5/de not_active IP Right Cessation
- 1999-11-19 ES ES99968206T patent/ES2172356T3/es not_active Expired - Lifetime
- 1999-11-19 AT AT99968206T patent/ATE213237T1/de not_active IP Right Cessation
- 1999-11-19 CZ CZ2001319A patent/CZ292174B6/cs not_active IP Right Cessation
- 1999-11-19 BR BR9917367-0A patent/BR9917367A/pt not_active IP Right Cessation
- 1999-11-19 DE DE19983486T patent/DE19983486C2/de not_active Expired - Fee Related
- 1999-11-19 DE DE69900891T patent/DE69900891D1/de not_active Expired - Lifetime
- 1999-11-19 HU HU0103417A patent/HUP0103417A3/hu unknown
- 1999-11-19 AT AT0904099A patent/AT409960B/de not_active IP Right Cessation
- 1999-11-19 GB GB0101508A patent/GB2354240B/en not_active Expired - Fee Related
- 1999-11-19 WO PCT/DK1999/000643 patent/WO2000011926A2/en active IP Right Grant
- 1999-11-19 SI SI9930039T patent/SI1105382T1/xx unknown
- 1999-11-19 EP EP99968206A patent/EP1105382B1/en not_active Expired - Lifetime
- 1999-11-19 TR TR2001/03700T patent/TR200103700T2/xx unknown
- 1999-11-19 UA UA2001117897A patent/UA62023C2/uk unknown
- 1999-11-22 CA CA002290125A patent/CA2290125C/en not_active Expired - Fee Related
2000
- 2000-06-21 AR ARP000103080A patent/AR020573A1/es unknown
2001
- 2001-01-19 NO NO20010318A patent/NO20010318L/no unknown
- 2001-01-24 SE SE0100194A patent/SE516689C2/sv not_active IP Right Cessation
- 2001-01-25 FI FI20010154A patent/FI108538B/fi not_active IP Right Cessation
- 2001-02-23 IS IS5862A patent/IS5862A/is unknown
- 2001-03-13 AT AT0018501U patent/AT4366U1/de not_active IP Right Cessation
- 2001-10-26 ZA ZA200108855A patent/ZA200108855B/xx unknown
- 2001-11-06 US US10/012,025 patent/US6750358B2/en not_active Expired - Fee Related
- 2001-12-07 BG BG106190A patent/BG106190A/xx unknown
2002
- 2002-12-24 HK HK02109330.8A patent/HK1047745B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
HUP0103417A3 (en)	2003-01-28
WO2000011926A2 (en)	2000-03-09
FI20010154L (fi)	2001-02-09
IL145960A0 (en)	2002-07-25
BG106190A (en)	2002-08-30
EA200101071A1 (ru)	2002-02-28
ITMI991579A0 (it)	1999-07-15
AU2001100433B4 (en)	2002-01-17
JP2002523432A (ja)	2002-07-30
DE69900891D1 (de)	2002-03-21
AT409960B (de)	2002-12-27
FI108538B (fi)	2002-02-15
GB2354240A (en)	2001-03-21
ITMI991579A1 (it)	2001-01-15
EP1105382B1 (en)	2002-02-13
HK1047745B (zh)	2004-09-10
NZ514982A (en)	2004-01-30
SE516689C2 (sv)	2002-02-12
DE19983486C2 (de)	2002-09-05
PL345971A1 (en)	2002-01-14
CA2290125C (en)	2004-08-10
BR9917367A (pt)	2002-03-05
TR200103700T2 (tr)	2002-05-21
KR20020011982A (ko)	2002-02-09
DK1105382T3 (da)	2002-05-27
ES2172356T3 (es)	2002-09-16
NO20010318L (no)	2001-02-20
IS5862A (is)	2001-02-23
CH691304A5 (de)	2001-06-29
PT1105382E (pt)	2002-07-31
ZA200108855B (en)	2002-08-28
CN1356993A (zh)	2002-07-03
CN1129593C (zh)	2003-12-03
GB0101508D0 (en)	2001-03-07
SI1105382T1 (en)	2002-06-30
JP3389571B2 (ja)	2003-03-24
CZ292174B6 (cs)	2003-08-13
SE0100194L (sv)	2001-04-25
AU2001100433A4 (en)	2001-11-01
HUP0103417A2 (hu)	2002-01-28
DE19983486T1 (de)	2001-10-18
AR020573A1 (es)	2002-05-15
CZ2001319A3 (en)	2001-05-16
EP1105382A2 (en)	2001-06-13
HK1047745A1 (en)	2003-03-07
NO20010318D0 (no)	2001-01-19
AT4366U1 (de)	2001-06-25
WO2000011926A3 (en)	2000-06-29
CA2290125A1 (en)	2000-12-25
US6750358B2 (en)	2004-06-15
GB2354240B (en)	2001-05-23
KR100491369B1 (ko)	2005-05-24
US20020061925A1 (en)	2002-05-23
MXPA01010986A (es)	2002-06-04
EA002661B1 (ru)	2002-08-29
ATA904099A (de)	2002-05-15
UA62023C2 (en)	2003-12-15
AU1374800A (en)	2000-03-21
ATE213237T1 (de)	2002-02-15
SE0100194D0 (sv)	2001-01-24

Publication	Publication Date	Title
SK18412001A3 (sk)	2002-05-09	Spôsob prípravy citalopramu a antidepresívny farmaceutický prostriedok vyrobený týmto spôsobom
SK285813B6 (sk)	2007-08-02	Spôsob prípravy citalopramu, farmaceutický prostriedok s obsahom citalopramu a medziprodukt
US6426422B1 (en)	2002-07-30	Method for the preparation of citalopram
US6762307B2 (en)	2004-07-13	Method for the preparation of citalopram
US6660873B2 (en)	2003-12-09	Method for the preparation of citalopram
CZ20023383A3 (cs)	2003-01-15	Způsob výroby citalopramu