SI9420001B - Polipeptidni antagonisti bombezina - Google Patents

Polipeptidni antagonisti bombezina Download PDF

Info

Publication number: SI9420001B
Authority: SI; Slovenia
Prior art keywords: alkyl; phenyl; hydrogen; peptide; moiety
Prior art date: 1993-03-15

Application number

SI9420001A

Other languages

English (en)

Slovenian (sl)

Other versions

SI9420001A (en

Inventor

Andrew V. Schally

Zhi Cai Ren

Original Assignee

The Administrators Of

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-03-15

Filing date

1994-03-07

Publication date

1999-08-31

1994-03-07 Application filed by The Administrators Of filed Critical The Administrators Of

1995-08-31 Publication of SI9420001A publication Critical patent/SI9420001A/sl

1999-08-31 Publication of SI9420001B publication Critical patent/SI9420001B/sl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C07K7/086—Bombesin; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Genetics & Genomics (AREA)
Animal Behavior & Ethology (AREA)
Biophysics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Epidemiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Enzymes And Modification Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

SI9420001A 1993-03-15 1994-03-07 Polipeptidni antagonisti bombezina SI9420001B (sl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/031,325 US5369094A (en)	1990-11-29	1993-03-15	Polypeptide bombesin antagonists
PCT/US1994/002511 WO1994021674A1 (en)	1993-03-15	1994-03-07	Polypeptide bombesin antagonists

Publications (2)

Publication Number	Publication Date
SI9420001A SI9420001A (en)	1995-08-31
SI9420001B true SI9420001B (sl)	1999-08-31

Family

ID=21858823

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI9420001A SI9420001B (sl)	1993-03-15	1994-03-07	Polipeptidni antagonisti bombezina

Country Status (27)

Country	Link
US (1)	US5369094A (ru)
EP (1)	EP0646127B1 (ru)
JP (1)	JP3838656B2 (ru)
KR (1)	KR100306506B1 (ru)
AT (1)	ATE167874T1 (ru)
AU (1)	AU666270B2 (ru)
BR (1)	BR9404341A (ru)
CA (1)	CA2135787C (ru)
CZ (1)	CZ286750B6 (ru)
DE (1)	DE69411342T2 (ru)
DK (1)	DK0646127T3 (ru)
EE (1)	EE03180B1 (ru)
ES (1)	ES2120615T3 (ru)
FI (1)	FI945378A0 (ru)
HR (1)	HRP940164B1 (ru)
HU (1)	HU218288B (ru)
IL (2)	IL108851A (ru)
NO (1)	NO313418B1 (ru)
NZ (2)	NZ299913A (ru)
PL (1)	PL180372B1 (ru)
RU (1)	RU2114118C1 (ru)
SI (1)	SI9420001B (ru)
SK (1)	SK282267B6 (ru)
TW (1)	TW325478B (ru)
UA (1)	UA34456C2 (ru)
WO (1)	WO1994021674A1 (ru)
ZA (1)	ZA941767B (ru)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5877277A (en)	1987-09-24	1999-03-02	Biomeasure, Inc.	Octapeptide bombesin analogs
US5723578A (en) *	1987-09-24	1998-03-03	The Administrators Of Tulane Educational Fund	Peptide analogs of bombesin
US5650395A (en) *	1995-03-13	1997-07-22	Hurel; Steven	Treatment of pulmonary hypertension
US6989371B1 (en)	1996-08-16	2006-01-24	Dabur Research Foundation	Bombesin analogs for treatment of cancer
DE69840647D1 (de) *	1997-04-22	2009-04-23	Curator Of The University Of M	Konjugate aus peptiden, die liganden von gastrinrezeptoren sind
IL155814A0 (en) *	2000-11-17	2003-12-23	Warner Lambert Co	Treatment of sexual dysfunction using bombesin antagonist
US20060239923A1 (en) *	2003-01-13	2006-10-26	Bracco Imaging S.P.A.	Gastrin releasing peptide compounds
US8420050B2 (en) *	2003-01-13	2013-04-16	Bracco Imaging S.P.A.	Gastrin releasing peptide compounds
US7611692B2 (en) *	2003-01-13	2009-11-03	Bracco Imaging S.P.A.	Gastrin releasing peptide compounds
US7922998B2 (en) *	2003-01-13	2011-04-12	Bracco Imaging S.P.A.	Gastrin releasing peptide compounds
US7850947B2 (en)	2003-01-13	2010-12-14	Bracco Imaging S.P.A.	Gastrin releasing peptide compounds
EP1583564B1 (en) *	2003-01-13	2009-07-01	Bracco Imaging S.p.A	Improved linkers for radiopharmaceutical compounds
US7226577B2 (en) *	2003-01-13	2007-06-05	Bracco Imaging, S. P. A.	Gastrin releasing peptide compounds
MXPA05011233A (es)	2003-04-22	2005-12-14	Conseils De Rech S Et D Aplica	Vectores peptidicos.
US7795385B2 (en) *	2004-12-17	2010-09-14	Bexar Global, Inc.	Use of bombesin/gastrin-releasing peptide antagonists for the treatment of inflammatory conditions, acute lung injury and bipolar disorder
FR2918566B1 (fr) *	2007-07-11	2009-10-09	Pierre Fabre Medicament Sa	Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
EP2100900A1 (en) *	2008-03-07	2009-09-16	Universitätsspital Basel	Bombesin analog peptide antagonist conjugates
EP2198878A1 (en) *	2008-12-18	2010-06-23	University Of Miami	Polypeptide bombesin antagonists
WO2011043954A1 (en)	2009-10-07	2011-04-14	Merck Sharp & Dohme Corp.	Novel trpa1 antagonists

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1989002897A1 (en) *	1987-09-24	1989-04-06	The Administrators Of The Tulane Educational Fund	Therapeutic peptides
US5084555A (en) *	1989-08-21	1992-01-28	The Administrators Of The Tulane Educational Fund	An octapeptide bombesin analog
US5162497A (en) *	1987-09-24	1992-11-10	The Administrators Of The Tulane Educational Fund	Bradykinin analogs with non-peptide bond
AU618029B2 (en) *	1987-11-02	1991-12-12	Imperial Chemical Industries Plc	Polypeptide compounds
GB8813356D0 (en) *	1988-06-06	1988-07-13	Ici Plc	Polypeptide compounds
GR1000608B (el) *	1988-07-21	1992-08-31	Erba Carlo Spa	Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
JP2919889B2 (ja) *	1988-10-14	1999-07-19	アドミニストレイターズオブザテューレインエデュケイショナルファンド	治療用ペプチド
US5217955A (en) *	1989-09-15	1993-06-08	Biomeasure, Inc.	Treatment of cancer with peptide analog of bombesin, grp, litorin or neuromedin
US5244883A (en) *	1990-11-29	1993-09-14	The Administrators Of The Tulane Educational Fund	Nonapeptide bombesin antagonists

1993
- 1993-03-15 US US08/031,325 patent/US5369094A/en not_active Expired - Lifetime
1994
- 1994-02-23 TW TW083101048A patent/TW325478B/zh not_active IP Right Cessation
- 1994-03-03 IL IL10885194A patent/IL108851A/xx not_active IP Right Cessation
- 1994-03-07 EP EP94912199A patent/EP0646127B1/en not_active Expired - Lifetime
- 1994-03-07 BR BR9404341-8A patent/BR9404341A/pt not_active Application Discontinuation
- 1994-03-07 ES ES94912199T patent/ES2120615T3/es not_active Expired - Lifetime
- 1994-03-07 SK SK1364-94A patent/SK282267B6/sk unknown
- 1994-03-07 NZ NZ299913A patent/NZ299913A/en not_active IP Right Cessation
- 1994-03-07 CZ CZ19942807A patent/CZ286750B6/cs not_active IP Right Cessation
- 1994-03-07 KR KR1019940704104A patent/KR100306506B1/ko not_active IP Right Cessation
- 1994-03-07 SI SI9420001A patent/SI9420001B/sl not_active IP Right Cessation
- 1994-03-07 AT AT94912199T patent/ATE167874T1/de not_active IP Right Cessation
- 1994-03-07 NZ NZ263668A patent/NZ263668A/en unknown
- 1994-03-07 WO PCT/US1994/002511 patent/WO1994021674A1/en active IP Right Grant
- 1994-03-07 CA CA002135787A patent/CA2135787C/en not_active Expired - Fee Related
- 1994-03-07 HU HU9403244A patent/HU218288B/hu not_active IP Right Cessation
- 1994-03-07 RU RU94046091A patent/RU2114118C1/ru not_active IP Right Cessation
- 1994-03-07 PL PL94306209A patent/PL180372B1/pl not_active IP Right Cessation
- 1994-03-07 DK DK94912199T patent/DK0646127T3/da active
- 1994-03-07 UA UA94119008A patent/UA34456C2/ru unknown
- 1994-03-07 AU AU64446/94A patent/AU666270B2/en not_active Ceased
- 1994-03-07 JP JP52109194A patent/JP3838656B2/ja not_active Expired - Fee Related
- 1994-03-07 DE DE69411342T patent/DE69411342T2/de not_active Expired - Fee Related
- 1994-03-10 HR HR08/031,325A patent/HRP940164B1/xx not_active IP Right Cessation
- 1994-03-14 ZA ZA941767A patent/ZA941767B/xx unknown
- 1994-11-10 NO NO19944293A patent/NO313418B1/no unknown
- 1994-11-15 FI FI945378A patent/FI945378A0/fi unknown
- 1994-11-23 EE EE9400166A patent/EE03180B1/xx not_active IP Right Cessation
2003
- 2003-03-19 IL IL15499503A patent/IL154995A0/xx unknown

Also Published As

Publication number	Publication date
ZA941767B (en)	1994-10-06
HUT69727A (en)	1995-09-28
RU2114118C1 (ru)	1998-06-27
DE69411342D1 (de)	1998-08-06
AU6444694A (en)	1994-10-11
NZ263668A (en)	1997-06-24
JP3838656B2 (ja)	2006-10-25
EP0646127A1 (en)	1995-04-05
HRP940164A2 (en)	1996-08-31
FI945378A (fi)	1994-11-15
EP0646127B1 (en)	1998-07-01
JPH07507330A (ja)	1995-08-10
UA34456C2 (ru)	2001-03-15
SK136494A3 (en)	1995-08-09
ES2120615T3 (es)	1998-11-01
IL108851A0 (en)	1994-06-24
IL108851A (en)	2003-05-29
NO944293D0 (no)	1994-11-10
FI945378A0 (fi)	1994-11-15
DK0646127T3 (da)	1999-04-12
US5369094A (en)	1994-11-29
RU94046091A (ru)	1996-09-27
KR950701646A (ko)	1995-04-28
PL306209A1 (en)	1995-03-06
BR9404341A (pt)	1999-08-31
CA2135787C (en)	2008-08-12
PL180372B1 (pl)	2001-01-31
DE69411342T2 (de)	1998-11-19
TW325478B (en)	1998-01-21
IL154995A0 (en)	2003-10-31
WO1994021674A1 (en)	1994-09-29
KR100306506B1 (ko)	2001-12-01
NO313418B1 (no)	2002-09-30
AU666270B2 (en)	1996-02-01
HU218288B (en)	2000-07-28
NO944293L (no)	1995-01-02
SI9420001A (en)	1995-08-31
CZ286750B6 (en)	2000-06-14
CA2135787A1 (en)	1994-09-29
EE03180B1 (et)	1999-04-15
ATE167874T1 (de)	1998-07-15
CZ280794A3 (en)	1995-07-12
HRP940164B1 (en)	2000-02-29
SK282267B6 (sk)	2001-12-03
NZ299913A (en)	2000-07-28

Publication	Publication Date	Title
SI9420001B (sl)	1999-08-31	Polipeptidni antagonisti bombezina
CA2097192A1 (en)	1992-05-30	Bombesin antagonists
GB1528336A (en)	1978-10-11	Compounds compositions and methods of their use
GB1532211A (en)	1978-11-15	Lh-rh peptide analogues
CA2067901A1 (en)	1992-11-03	Novel polypeptides with affinity to lipopolysaccharides and their uses
GB1533077A (en)	1978-11-22	4-substituted enkephalin derivatives
GB1526367A (en)	1978-09-27	Polypeptide
PT78209B (en)	1986-04-24	Gnrh antagonists iii
DE2158123A1 (de)	1972-06-08	Neue pharmazeutische Präparate
DE3267380D1 (en)	1985-12-19	Peptides and pseudopeptides in which the n terminus bears two substituents
KR920701242A (ko)	1992-08-11	환원된 비가역성 봄베신 길항제
ES416516A1 (es)	1976-03-01	Un procedimiento para la preparacion de nonapeptidos.
GB1357121A (en)	1974-06-19	Peptide enzyme inhibitors
ES248724A1 (es)	1960-01-01	Procedimiento para la obtenciën de nuevosdecapeptures ciclicos
GB1430522A (en)	1976-03-31	N-substituted aspartyl peptide amides
GB1273873A (en)	1972-05-10	Corticotropically highly active octadecapeptides
Lübke et al.	1966	The Influence of Substitution or Omission of an Amino Group on the Hypotensive Activity of the C-Terminal Sequences of Eledoisin
FR4219M (ru)	1966-07-18
GB1037143A (en)	1966-07-27	Polypeptides
GB1532148A (en)	1978-11-15	1-substituted enkepholin derivatives
HRP921277A2 (en)	1997-08-31	Nonapeptide bombestin antagonists
TH17064B (th)	2004-06-18	ตัวปฏิปักษ์ต่อโปลีเปปไทด์บอมเบซิน

Legal Events

Date	Code	Title	Description
2005-01-10	IF	Valid on the event date
2008-12-31	KO00	Lapse of patent	Effective date: 20081112