[go: up one dir, main page]

SG155206A1 - Vaccine for prevention and treatment of hiv-infection - Google Patents

Vaccine for prevention and treatment of hiv-infection

Info

Publication number
SG155206A1
SG155206A1 SG200905319-0A SG2009053190A SG155206A1 SG 155206 A1 SG155206 A1 SG 155206A1 SG 2009053190 A SG2009053190 A SG 2009053190A SG 155206 A1 SG155206 A1 SG 155206A1
Authority
SG
Singapore
Prior art keywords
hiv
gag
vaccine
infection
prevention
Prior art date
Application number
SG200905319-0A
Other languages
English (en)
Inventor
Helge Abrecht
Martine Delchambre
Martine Marchand
Nathalie Louise Mathy
Philippe Jean Gervais Ghislain Permanne
Gerald Hermann Voss
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Publication of SG155206A1 publication Critical patent/SG155206A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
    • A61K2039/645—Dendrimers; Multiple antigen peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG200905319-0A 2004-08-05 2005-08-03 Vaccine for prevention and treatment of hiv-infection SG155206A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0417494.2A GB0417494D0 (en) 2004-08-05 2004-08-05 Vaccine

Publications (1)

Publication Number Publication Date
SG155206A1 true SG155206A1 (en) 2009-09-30

Family

ID=32982606

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200905319-0A SG155206A1 (en) 2004-08-05 2005-08-03 Vaccine for prevention and treatment of hiv-infection

Country Status (32)

Country Link
US (2) US7612173B2 (fr)
EP (3) EP1773999B1 (fr)
JP (3) JP2008507987A (fr)
KR (1) KR101501495B1 (fr)
CN (2) CN102633866B (fr)
AR (2) AR050102A1 (fr)
AT (1) ATE443769T1 (fr)
AU (1) AU2005268856B2 (fr)
BR (1) BRPI0514108A (fr)
CA (1) CA2575898C (fr)
CY (1) CY1109667T1 (fr)
DE (1) DE602005016810D1 (fr)
DK (1) DK1773999T3 (fr)
ES (3) ES2486669T3 (fr)
GB (1) GB0417494D0 (fr)
HK (1) HK1108168A1 (fr)
HR (1) HRP20090678T1 (fr)
IL (2) IL180947A0 (fr)
MA (1) MA28983B1 (fr)
MX (1) MX2007001515A (fr)
MY (1) MY145614A (fr)
NO (1) NO20070988L (fr)
NZ (1) NZ552976A (fr)
PE (1) PE20060577A1 (fr)
PL (1) PL1773999T3 (fr)
PT (1) PT1773999E (fr)
RU (1) RU2441878C2 (fr)
SG (1) SG155206A1 (fr)
SI (1) SI1773999T1 (fr)
TW (1) TWI365191B (fr)
WO (1) WO2006013106A2 (fr)
ZA (1) ZA200700771B (fr)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020048596A1 (en) * 1994-12-30 2002-04-25 Gregor Cevc Preparation for the transport of an active substance across barriers
EP1039880A1 (fr) * 1998-10-23 2000-10-04 Idea Innovative Dermale Applikationen GmbH Procede pour mettre au point, tester et utiliser des produits resultant de l'association de macromolecules et d'agregats de complexes, en vue d'ameliorer la charge utile et de reguler les vitesses de dissociation/association
ATE216875T1 (de) 1999-01-27 2002-05-15 Idea Ag Nichtinvasive impfung durch die haut
EP1031347B1 (fr) 1999-01-27 2002-04-17 Idea Ag Transport/immunisation transnasale avec véhicules très adaptables
WO2001001962A1 (fr) * 1999-07-05 2001-01-11 Idea Ag. Procede d'amelioration du transport a travers des barrieres semi-permeables compatibles
US20040105881A1 (en) * 2002-10-11 2004-06-03 Gregor Cevc Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin
TW200510425A (en) * 2003-08-13 2005-03-16 Japan Tobacco Inc Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor
EP1811961A2 (fr) * 2004-11-12 2007-08-01 Idea Ag Agregats a grande surface pour le traitement de troubles cutanes
TW200716750A (en) * 2005-05-12 2007-05-01 Glaxo Group Ltd Vaccine composition
EP2963118B1 (fr) 2005-06-01 2017-08-09 California Institute of Technology Procede permettant le transfert cible de genes au moyen de vecteurs viraux
JP2009536653A (ja) * 2006-05-09 2009-10-15 ザ ヘンリー エム． ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド Ｈｉｖ−１免疫原性組成物
PT2048955E (pt) * 2006-07-21 2013-09-20 California Inst Of Techn Administração de gene alvo para vacinação de células dendríticas
PL2137210T3 (pl) * 2007-03-02 2017-06-30 Glaxosmithkline Biologicals Sa Nowy sposób i kompozycje
US9717788B2 (en) * 2007-03-02 2017-08-01 Glaxosmithkline Biologicals Sa Method of inducing an immune response against HIV employing HIV immunogens, adenoviral vectors encoding said immunogens, and adjuvant
US20110244496A1 (en) * 2007-03-06 2011-10-06 Rutgers, The State University Hiv reverse transcriptase compositions and methods
EP2142212A2 (fr) * 2007-03-26 2010-01-13 International Aids Vaccine Initiative Vaccins contre le vih-1 basés sur le virus ankara modifié recombiné
KR101238795B1 (ko) 2007-05-24 2013-03-07 글락소스미스클라인 바이오로지칼즈 에스.에이. 동결건조 항원 조성물
AU2008339984A1 (en) * 2007-12-21 2009-07-02 Glaxosmithkline Biologicals S.A. Vaccine
NZ596171A (en) 2008-07-16 2012-05-25 Baylor Res Inst Hiv vaccine based on targeting maximized gag and nef to dendritic cells
GB0815872D0 (en) * 2008-09-01 2008-10-08 Pasteur Institut Novel method and compositions
EP2344143A1 (fr) 2008-09-09 2011-07-20 Mukesh Harilal Shukla Composition bioactive destinée au traitement du vih/sida, et procédé de fabrication et d utilisation de celle-ci
MX2012001075A (es) 2009-07-24 2012-05-22 Immune Design Corp Vectores lentivirales pseudotipificados con una glicoproteina de envoltura de virus sindbis.
WO2011117408A1 (fr) * 2010-03-26 2011-09-29 Glaxosmithkline Biologicals S.A. Vaccin contre le hiv
JP6030052B2 (ja) * 2010-05-14 2016-11-24 バクスアルタ インコーポレイテッド Ｏｓｐａキメラおよびそのワクチンでの使用法
EP2621528A1 (fr) * 2010-09-27 2013-08-07 GlaxoSmithKline Biologicals S.A. Vaccin
JP2012120506A (ja) * 2010-12-10 2012-06-28 Tosoh Corp Ａｍｖ逆転写酵素遺伝子、該遺伝子によりコードされるａｍｖ逆転写酵素及び該遺伝子を用いるａｍｖ逆転写酵素の製造方法
GB201022007D0 (en) 2010-12-24 2011-02-02 Imp Innovations Ltd DNA-sensor
JP2013146235A (ja) * 2012-01-20 2013-08-01 Tosoh Corp トリ骨髄芽細胞腫ウイルス逆転写酵素の製造方法
EP2620446A1 (fr) 2012-01-27 2013-07-31 Laboratorios Del Dr. Esteve, S.A. Immunogènes pour la vaccination contre le VIH
US9713635B2 (en) 2012-03-30 2017-07-25 Immune Design Corp. Materials and methods for producing improved lentiviral vector particles
US8323662B1 (en) 2012-03-30 2012-12-04 Immune Design Corp. Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein
MX362699B (es) 2012-03-30 2019-02-01 Immune Design Corp Partículas de vectores lentivirales teniendo eficiencia de transducción mejorada para células que expresan dc-sign.
WO2014160747A2 (fr) 2013-03-26 2014-10-02 Globeimmune, Inc. Compositions et méthodes de traitement ou de prévention d'une infection par le virus de l'immunodéficience humaine
PL3166607T3 (pl) 2014-07-11 2023-02-20 Gilead Sciences, Inc. Modulatory receptorów toll-podobnych do leczenia hiv
KR102014518B1 (ko) 2017-01-05 2019-08-26 서울대학교산학협력단 HIV 1의 p24 단백질을 발현하는 벡터가 도입된 재조합 마이코박테리움 스메그마티스 균주 및 이를 포함하는 백신
GB201812647D0 (en) 2018-08-03 2018-09-19 Chancellor Masters And Scholars Of The Univ Of Oxford Viral vectors and methods for the prevention or treatment of cancer
CN114761041A (zh) 2019-07-16 2022-07-15 吉利德科学公司 Hiv疫苗及其制备和使用方法
BR112022009421A2 (pt) 2019-11-14 2022-10-25 Aelix Therapeutics S L Regimes de dosagem para vacinas
CN115666634A (zh) 2020-03-27 2023-01-31 瑞典疫苗制药有限公司 用于治疗和预防冠状病毒的组合物和方法
EP4277652A1 (fr) 2021-01-14 2023-11-22 Gilead Sciences, Inc. Vaccins contre le vih et méthodes d'utilisation
TW202330575A (zh) 2021-09-29 2023-08-01 瑞典商斯文斯卡疫苗生產股份有限公司 用於治療及預防冠狀病毒之組成物及方法

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235877A (en) 1979-06-27 1980-11-25 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit
US4372945A (en) 1979-11-13 1983-02-08 Likhite Vilas V Antigen compounds
IL61904A (en) 1981-01-13 1985-07-31 Yeda Res & Dev Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same
US4436727A (en) 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
DE3300234A1 (de) 1983-01-05 1984-07-05 Display-Design GmbH für moderne Verkaufsförderungsmittel und Raumaussstattung, 6233 Kelkheim Etagenturm zur warenausstellung
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
CA1331443C (fr) 1987-05-29 1994-08-16 Charlotte A. Kensil Adjuvant a saponine
DK643188A (da) * 1987-11-24 1989-05-25 Smithkline Biolog Ekspression af hiv-proteiner i e.coli og s.cerevisiae
US5221610A (en) * 1988-05-26 1993-06-22 Institut Pasteur Diagnostic method and composition for early detection of HIV infection
EP0468520A3 (en) 1990-07-27 1992-07-01 Mitsui Toatsu Chemicals, Inc. Immunostimulatory remedies containing palindromic dna sequences
JP3723231B2 (ja) 1991-12-23 2005-12-07 ディミナコ アクチェンゲゼルシャフト アジュバント
KR0172970B1 (ko) 1992-06-17 1999-02-01 김영길 Aids백신에 유용한 키메릭 단백 및 그의 제조방법
DK0761231T3 (da) 1992-06-25 2000-05-08 Smithkline Beecham Biolog Vaccinepræparat indeholdende adjuvanser
DE69405551T3 (de) 1993-03-23 2005-10-20 Smithkline Beecham Biologicals S.A. 3-0-deazylierte monophosphoryl lipid a enthaltende impfstoff-zusammensetzungen
US5962635A (en) * 1993-05-18 1999-10-05 Biomolecular Research Institute Ltd. Therapeutic compounds
WO1995014026A1 (fr) 1993-11-17 1995-05-26 Laboratoires Om S.A. Disaccharides de glucosamine, leur procede de preparation, composition pharmaceutique les contenant, et leurs utilisations
GB9326253D0 (en) 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
WO1996002555A1 (fr) 1994-07-15 1996-02-01 The University Of Iowa Research Foundation Oligonucleotides immunomodulateurs
AUPM873294A0 (en) 1994-10-12 1994-11-03 Csl Limited Saponin preparations and use thereof in iscoms
GB9620795D0 (en) 1996-10-05 1996-11-20 Smithkline Beecham Plc Vaccines
UA56132C2 (uk) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
AU4255397A (en) 1996-09-06 1998-03-26 Trustees Of The University Of Pennsylvania, The Chimpanzee adenovirus vectors
AU4992197A (en) 1996-10-11 1998-05-11 Regents Of The University Of California, The Immunostimulatory polynucleotide/immunomodulatory molecule conjugates
GB9711990D0 (en) 1997-06-11 1997-08-06 Smithkline Beecham Biolog Vaccine
JP5220248B2 (ja) 1997-08-29 2013-06-26 アンチジェニックス・インコーポレイテッド アジュバントｑｓ−２１および賦形剤としてポリソルベートまたはシクロデキストリンを含む組成物
CA2302554C (fr) 1997-09-05 2007-04-10 Smithkline Beecham Biologicals S.A. Emulsions huile-dans-l'eau contenant des saponines
GB9718901D0 (en) 1997-09-05 1997-11-12 Smithkline Beecham Biolog Vaccine
GB9720585D0 (en) 1997-09-26 1997-11-26 Smithkline Beecham Biolog Vaccine
AU762376C (en) 1998-08-04 2004-10-14 Henry M. Jackson Foundation, The Expression and characterization of HIV-1 envelope protein associated with a broadly reactive neutralizing antibody response
AU782193B2 (en) 1999-12-17 2005-07-07 Merck & Co., Inc. Polynucleotide vaccines expressing codon optimized HIV-1 Nef and modified HIV-1 Nef
DK1240186T3 (da) * 1999-12-23 2010-05-31 Medical Res Council Forbedringer i eller relateret til immunrespons mod HIV
US20020155127A1 (en) * 2000-06-02 2002-10-24 Danher Wang Genetic vaccine against human immunodeficiency virus
AU2001294562B2 (en) 2000-09-15 2007-05-24 Merck & Co., Inc. Enhanced First Generation Adenovirus Vaccines Expressing Codon Optimized HIV1-Gag, Pol, Nef and Modifications
CU23235A1 (es) 2001-02-28 2007-09-26 Ct Ingenieria Genetica Biotech POXVIRUS RECOMBINANTES PARA PROTEINAS QUIMéRICAS DEL VIRUS DE LA INMUNODEFICIENCIA HUMANA Y SU APLICACION EN LA TERAPéUTICA Y LA PREVENCION DEL SIDA
EP1434859A2 (fr) * 2001-07-25 2004-07-07 New York University Utilisation de glycosylceramides comme adjuvants pour des vaccins contre les infections et le cancer
EP1427826B1 (fr) * 2001-09-20 2011-04-20 Glaxo Group Limited Vaccins VIH-RT-nef-Gag à DNA avec codons optimisés
IL161584A0 (en) 2001-11-21 2004-09-27 Univ Pennsylvania Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use
AU2002360429A1 (en) 2001-11-26 2003-06-10 Avigen, Inc. Methods for producing stocks of recombinant aav virions
US20030190308A1 (en) * 2002-03-19 2003-10-09 Braun Ralph P. Adjuvant
US20050266024A1 (en) * 2002-03-19 2005-12-01 Powdermed Limited Adjuvant
ES2285174T3 (es) * 2002-06-11 2007-11-16 Glaxosmithkline Biologicals S.A. Composiciones inmunogenicas.
GB0225788D0 (en) 2002-11-05 2002-12-11 Glaxo Group Ltd Vaccine
GB0225786D0 (en) * 2002-11-05 2002-12-11 Glaxo Group Ltd Vaccine
US7501503B2 (en) * 2002-12-31 2009-03-10 Mcgill University Compositions and methods for inhibiting RNase H activity of retroid reverse transcriptase
US20050175627A1 (en) * 2003-09-24 2005-08-11 Oxxon Therapeutics Ltd. HIV pharmaccines
CA2539864A1 (fr) 2003-09-24 2005-04-07 Oxxon Therapeutics Limited Vaccins pharmaceutiques contre le vih

Also Published As

Publication number Publication date
CN101035897A (zh) 2007-09-12
HK1108168A1 (en) 2008-05-02
JP2011234722A (ja) 2011-11-24
AU2005268856A1 (en) 2006-02-09
TWI365191B (en) 2012-06-01
EP2130921A3 (fr) 2010-03-03
PT1773999E (pt) 2009-12-16
CA2575898C (fr) 2015-09-29
MX2007001515A (es) 2007-09-07
SI1773999T1 (sl) 2010-01-29
MY145614A (en) 2012-03-15
US20100184836A1 (en) 2010-07-22
RU2441878C2 (ru) 2012-02-10
BRPI0514108A (pt) 2008-05-27
NO20070988L (no) 2007-05-04
IL180947A0 (en) 2007-07-04
WO2006013106A3 (fr) 2006-08-17
GB0417494D0 (en) 2004-09-08
DE602005016810D1 (de) 2009-11-05
EP2130921A2 (fr) 2009-12-09
KR101501495B1 (ko) 2015-03-11
CA2575898A1 (fr) 2006-02-09
JP5629647B2 (ja) 2014-11-26
KR20070041765A (ko) 2007-04-19
AR050102A1 (es) 2006-09-27
TW200621806A (en) 2006-07-01
US7612173B2 (en) 2009-11-03
US20070243203A1 (en) 2007-10-18
RU2007104088A (ru) 2008-09-10
EP2280073A2 (fr) 2011-02-02
EP1773999A2 (fr) 2007-04-18
ES2486669T3 (es) 2014-08-19
CY1109667T1 (el) 2014-08-13
MA28983B1 (fr) 2007-11-01
HRP20090678T1 (hr) 2010-01-31
IL207575A0 (en) 2011-07-31
ES2445453T3 (es) 2014-03-03
EP2280073B1 (fr) 2014-06-11
NZ552976A (en) 2010-01-29
JP2014239687A (ja) 2014-12-25
EP1773999B1 (fr) 2009-09-23
JP2008507987A (ja) 2008-03-21
DK1773999T3 (da) 2010-01-18
ATE443769T1 (de) 2009-10-15
CN101035897B (zh) 2012-02-01
EP2280073A3 (fr) 2011-06-29
ZA200700771B (en) 2009-04-29
WO2006013106A2 (fr) 2006-02-09
ES2334044T3 (es) 2010-03-04
AR080216A2 (es) 2012-03-21
JP6007212B2 (ja) 2016-10-12
CN102633866B (zh) 2015-04-15
PL1773999T3 (pl) 2010-02-26
CN102633866A (zh) 2012-08-15
EP2130921B1 (fr) 2013-11-20
PE20060577A1 (es) 2006-08-07
AU2005268856B2 (en) 2012-05-24

Similar Documents

Publication Publication Date Title
SG155206A1 (en) Vaccine for prevention and treatment of hiv-infection
EA200200724A1 (ru) Вакцина для профилактической или терапевтической иммунизации против вируса иммунодефицита человека (вич)
PE20061372A1 (es) Composicion farmaceutica que contiene un vector adenovirus
EA201000829A1 (ru) Вакцина
MY136081A (en) Modified hiv - 1gag p17 peptide and immunogenic composition
EA200001030A1 (ru) Получение капсул и таблеток быстрорастворяющегося эфавиренза с использованием супердезинтеграторов
TW200726479A (en) Method of inducing neutralizing antibodies to human immunodeficiency virus
CY1111636T1 (el) Εμβολιο που περιεχει gp120 και nef kai/´h tat για ανοσοποιηση εναντι hiv
NZ597458A (en) Hiv related peptides combination or fusion for use in hiv vaccine composition or as diagnostic means
EA200700904A1 (ru) Вакцины против вируса японского энцефалита и вируса западного нила
CO5560591A2 (es) Vacunas de adn optimizadas por el codon vih-gag
AU8499901A (en) Modifications of hiv env, gag, and pol enhance immunogenicity for genetic immunization
SG178909A1 (en) Generation of a broad t-cell response in humans against hiv
MX2022000879A (es) Vacuna viral terapeutica.
EP1471936A4 (fr) Vaccin contre le vih et procede d'utilisation
WO2003080112A3 (fr) Adjuvant
WO2003052122A3 (fr) Inhibiteur de gp41
WO2007018550A3 (fr) Compositions et methodes pour detecter une infection par le vih-1/vih-2
WO2005089231A3 (fr) Activite renforcee de vaccin vih utilisant un oligonucleotide immunomodulateur de seconde generation
WO2004039945A3 (fr) Vaccins preventifs et therapeutiques contre le sida
WO2006085979A3 (fr) Formes solubles de glycoproteine g des virus hendra et nipah
WO2007025276A3 (fr) Utilisation de complexes cd4/enveloppe du vih pour la generation d'anticorps et comme complexes immunogenes
FR2868318B1 (fr) Antigene tat stabilise et ses applications pour la vaccination anti-vih
WO2010135663A3 (fr) Compositions et procédés pour détecter une infection par le vih-1/vih-2
ATE324450T1 (de) Polypeptid, das neutralisierende antikörper gegen hiv induziert