SG145724A1 - Recombinant lubricin molecules and uses thereof - Google Patents

Recombinant lubricin molecules and uses thereof

Info

Publication number: SG145724A1
Authority: SG; Singapore
Prior art keywords: recombinant lubricin; lubricin molecules; molecules; recombinant; pleura
Prior art date: 2003-08-14

Application number

SG200805896-8A

Other languages

English (en)

Inventor

Carl Ralph Flannery

Christopher John Corcoran

Bethany Annis Freeman

Lisa Anne Racie

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-08-14

Filing date

2004-08-13

Publication date

2008-09-29

2004-08-13 Application filed by Wyeth Corp filed Critical Wyeth Corp

2008-09-29 Publication of SG145724A1 publication Critical patent/SG145724A1/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Immunology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Physical Education & Sports Medicine (AREA)
Marine Sciences & Fisheries (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Neurosurgery (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

SG200805896-8A 2003-08-14 2004-08-13 Recombinant lubricin molecules and uses thereof SG145724A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US49574103P	2003-08-14	2003-08-14

Publications (1)

Publication Number	Publication Date
SG145724A1 true SG145724A1 (en)	2008-09-29

Family

ID=34193342

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG200805896-8A SG145724A1 (en)	2003-08-14	2004-08-13	Recombinant lubricin molecules and uses thereof

Country Status (21)

Country	Link
US (6)	US7642236B2 (zh)
EP (1)	EP1663291B1 (zh)
JP (1)	JP2007502122A (zh)
KR (1)	KR101078202B1 (zh)
CN (2)	CN1867350A (zh)
AU (2)	AU2004264970B2 (zh)
BR (1)	BRPI0413553A (zh)
CR (1)	CR8204A (zh)
DK (1)	DK1663291T3 (zh)
EC (1)	ECSP066364A (zh)
ES (1)	ES2388970T3 (zh)
HK (1)	HK1089110A1 (zh)
IL (2)	IL173258A (zh)
MX (1)	MXPA06001658A (zh)
NO (1)	NO20060475L (zh)
NZ (1)	NZ545021A (zh)
RU (2)	RU2376313C2 (zh)
SG (1)	SG145724A1 (zh)
UA (1)	UA91818C2 (zh)
WO (1)	WO2005016130A2 (zh)
ZA (1)	ZA200601291B (zh)

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US6743774B1 (en) *	1999-04-23	2004-06-01	Rhode Island Hospital	Tribonectins
CA2575086A1 (en) *	2004-07-23	2006-02-02	Mucosal Therapeutics Llc	Compositions and methods for viscosupplementation
US20090068247A1 (en) *	2007-09-12	2009-03-12	Mucosal Therapeutics	Biocompatible devices coated with a tribonectin and methods for their production
US20090104148A1 (en) *	2007-09-18	2009-04-23	Jay Gregory D	Treatment and prevention of joint disease
PT2915529T (pt)	2008-05-07	2017-07-24	Univ California	Reposição e enriquecimento terapêutico de lubrificação da superficie ocular
US8506944B2 (en)	2008-05-07	2013-08-13	The Regents Of The University Of California	Replenishment and enrichment of ocular surface lubrication
US8980840B2 (en)	2009-01-13	2015-03-17	Schepens Eye Research Institute	Therapeutic modulation of vaginal epithelium boundary lubrication
WO2010135736A2 (en) *	2009-05-22	2010-11-25	Singularis Inc.	Application and uses of prg4 and therapeutic modulation thereof
ES2627103T3 (es) *	2010-01-19	2017-07-26	Lubris Llc	Composiciones de cuidado bucal y métodos
US8716204B2 (en)	2010-07-27	2014-05-06	Zimmer, Inc.	Synthetic synovial fluid compositions and methods for making the same
US20130116186A1 (en) *	2011-10-04	2013-05-09	Rhode Island Hospital, A Lifespan Partner	Lubricin injections to maintain cartilage health
EP2948553B1 (en)	2013-01-25	2020-04-01	Baylor College Of Medicine	A helper-dependent adenoviral gene therapy delivery and expression system
US20150010606A1 (en) *	2013-07-08	2015-01-08	Arthrex, Inc.	Intra-articular injection and implant attachment of molecule consisting of lubricin and extracellular superoxide dismutase or hyaluronic acid and extracellular superoxide dismutase
WO2015057993A1 (en) *	2013-10-16	2015-04-23	Ensisheim Partners Llc	Protein-specific formulations
WO2015060935A1 (en)	2013-10-22	2015-04-30	Lubris, Llc	Control of rheological properties of mixed hyaluronate/lubricin solutions
AU2014354859B2 (en)	2013-11-26	2020-04-09	Lubris Llc	Compositions and methods for inhibiting intercellular interactions
ES2808199T3 (es)	2015-01-26	2021-02-25	Lubris Llc	Uso de PRG4 como un agente antiinflamatorio
AR108683A1 (es)	2016-01-13	2018-09-19	Merial Inc	Vectores aav recombinantes que expresan genes osteoprotectores que incluyen has2 y lubricina, de utilidad en el tratamiento de la osteoartritis y afecciones articulares relacionadas en mamíferos
US11028410B2 (en)	2016-01-27	2021-06-08	Just-Evotec Biologics, Inc.	Hybrid promoter and uses thereof
WO2019246522A1 (en) *	2018-06-21	2019-12-26	Lubris Llc	Lubricin for use in wound healing
WO2020150396A1 (en) *	2019-01-15	2020-07-23	Cornell University	Recombinant lubricins, and compositions and methods for using the same
BR112022016481A2 (pt) *	2020-02-24	2022-10-25	Novartis Ag	Purificação de polipeptídeos recombinantemente produzidos
IT202000022636A1 (it)	2020-09-25	2022-03-25	Ente Ospedaliero Specializzato In Gastroenterologia Istituto Nazionale Di Ricovero E Cura A Caratter	“terapia di combinazione di sorafenib e/o regorafenib con la proteina ricombinante umana proteoglicano-4 per il trattamento dell'epatocarcinoma”

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2004
- 2004-08-13 EP EP04781229A patent/EP1663291B1/en not_active Expired - Lifetime
- 2004-08-13 KR KR1020067003110A patent/KR101078202B1/ko not_active IP Right Cessation
- 2004-08-13 CN CNA2004800299041A patent/CN1867350A/zh active Pending
- 2004-08-13 SG SG200805896-8A patent/SG145724A1/en unknown
- 2004-08-13 CN CN2012104146501A patent/CN102924584A/zh active Pending
- 2004-08-13 DK DK04781229.2T patent/DK1663291T3/da active
- 2004-08-13 BR BRPI0413553-9A patent/BRPI0413553A/pt not_active IP Right Cessation
- 2004-08-13 US US10/567,764 patent/US7642236B2/en not_active Expired - Fee Related
- 2004-08-13 UA UAA200602706A patent/UA91818C2/ru unknown
- 2004-08-13 AU AU2004264970A patent/AU2004264970B2/en not_active Ceased
- 2004-08-13 JP JP2006523436A patent/JP2007502122A/ja active Pending
- 2004-08-13 NZ NZ545021A patent/NZ545021A/en not_active IP Right Cessation
- 2004-08-13 ES ES04781229T patent/ES2388970T3/es not_active Expired - Lifetime
- 2004-08-13 RU RU2006107925/13A patent/RU2376313C2/ru not_active IP Right Cessation
- 2004-08-13 WO PCT/US2004/026508 patent/WO2005016130A2/en active Application Filing
- 2004-08-13 MX MXPA06001658A patent/MXPA06001658A/es active IP Right Grant
2006
- 2006-01-19 CR CR8204A patent/CR8204A/es unknown
- 2006-01-19 IL IL173258A patent/IL173258A/en not_active IP Right Cessation
- 2006-01-30 NO NO20060475A patent/NO20060475L/no not_active Application Discontinuation
- 2006-02-13 ZA ZA200601291A patent/ZA200601291B/xx unknown
- 2006-02-14 EC EC2006006364A patent/ECSP066364A/es unknown
- 2006-10-10 HK HK06111118.8A patent/HK1089110A1/xx unknown
2009
- 2009-06-24 IL IL199528A patent/IL199528A/en not_active IP Right Cessation
- 2009-08-07 RU RU2009130434/10A patent/RU2009130434A/ru not_active Application Discontinuation
- 2009-11-19 US US12/622,141 patent/US7893029B2/en not_active Expired - Fee Related
- 2009-11-23 US US12/624,112 patent/US7897571B2/en not_active Expired - Fee Related
2010
- 2010-04-16 AU AU2010201537A patent/AU2010201537B2/en not_active Ceased
2011
- 2011-02-25 US US13/035,529 patent/US8420793B2/en not_active Expired - Fee Related
2013
- 2013-03-08 US US13/791,346 patent/US8987205B2/en not_active Expired - Fee Related
2015
- 2015-02-05 US US14/614,809 patent/US20150343019A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US7642236B2 (en)	2010-01-05
NZ545021A (en)	2009-03-31
ES2388970T3 (es)	2012-10-22
HK1089110A1 (en)	2006-11-24
US8420793B2 (en)	2013-04-16
JP2007502122A (ja)	2007-02-08
US20070191268A1 (en)	2007-08-16
NO20060475L (no)	2006-03-13
CN1867350A (zh)	2006-11-22
US20100080848A1 (en)	2010-04-01
IL173258A (en)	2010-12-30
US20100074935A1 (en)	2010-03-25
CN102924584A (zh)	2013-02-13
WO2005016130A2 (en)	2005-02-24
AU2010201537A1 (en)	2010-05-06
AU2010201537B2 (en)	2012-02-23
DK1663291T3 (da)	2012-07-02
BRPI0413553A (pt)	2006-10-17
KR101078202B1 (ko)	2011-11-01
RU2376313C2 (ru)	2009-12-20
EP1663291A4 (en)	2009-08-05
MXPA06001658A (es)	2006-04-28
US20130196930A1 (en)	2013-08-01
WO2005016130A3 (en)	2006-02-02
AU2004264970A1 (en)	2005-02-24
IL199528A (en)	2013-03-24
KR20060072124A (ko)	2006-06-27
CR8204A (es)	2007-10-01
RU2009130434A (ru)	2011-02-20
IL199528A0 (en)	2011-08-01
US7893029B2 (en)	2011-02-22
US8987205B2 (en)	2015-03-24
IL173258A0 (en)	2006-06-11
ZA200601291B (en)	2010-08-25
US20150343019A1 (en)	2015-12-03
RU2006107925A (ru)	2006-07-27
AU2004264970B2 (en)	2010-02-11
ECSP066364A (es)	2006-08-30
EP1663291A2 (en)	2006-06-07
UA91818C2 (ru)	2010-09-10
US7897571B2 (en)	2011-03-01
US20110189731A1 (en)	2011-08-04
EP1663291B1 (en)	2012-06-06

Publication	Publication Date	Title
SG145724A1 (en)	2008-09-29	Recombinant lubricin molecules and uses thereof
RS50660B (sr)	2010-06-30	Dihidrotetrabenazini i farmaceutske kompozicije koje ih sadrže
SG159547A1 (en)	2010-03-30	Methods and compositions for modulating hyperstabilized c-met
HK1122843A1 (en)	2009-05-29	Compositions of trna and uses thereof trna
WO2006127768A3 (en)	2009-06-04	Microscale micropatterned engineered in vitor tissue
WO2006128685A3 (en)	2007-04-19	Process for making a low molecular weight gelatine hydrolysate and gelatine hydrolysate compositions
BRPI0513958A (pt)	2008-05-20	junta de engate de vagão ferroviário possuindo superfìcie de apoio aperfeiçoada
NO20090047L (no)	2009-03-05	Anti-DLL4-antistoffer og fremgangsmater for anvendelse av disse
CY1113199T1 (el)	2016-04-13	Σταθεροποιημενες συνθεσεις γλυκοσερεμπροσιδασης
EA200701528A1 (ru)	2007-12-28	Новые нутрицевтические композиции
MX2009007763A (es)	2009-07-30	Mousse.
TW200722897A (en)	2007-06-16	Projection partitioning and aligning
BR0211293B1 (pt)	2011-11-01	processo para produzir continuamente uma composição elastomérica.
BRPI0702163A (pt)	2007-12-11	composições de toner e métodos
SI2327792T1 (sl)	2013-12-31	Postopki in sestavki za detektiranje avtoimunskih motenj
WO2006012492A8 (en)	2006-12-28	Compositions and methods for viscosupplementation
BRPI0810130A8 (pt)	2016-09-20	Composição de bebida, processo para produzir uma composição de bebida, e, uso de uma composição de bebida
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