RS50660B - Dihidrotetrabenazini i farmaceutske kompozicije koje ih sadrže - Google Patents
Dihidrotetrabenazini i farmaceutske kompozicije koje ih sadržeInfo
- Publication number
- RS50660B RS50660B RSP-2008/0550A RSP20080550A RS50660B RS 50660 B RS50660 B RS 50660B RS P20080550 A RSP20080550 A RS P20080550A RS 50660 B RS50660 B RS 50660B
- Authority
- RS
- Serbia
- Prior art keywords
- dihydrotetrabenazines
- pharmaceutical compositions
- compositions containing
- dihydrotetrabenazine
- cis
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
- C07D455/06—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine containing benzo [a] quinolizine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
3,11 b-cis-dihidrotetrabenazin. Prijava sadrži još 28 patentnih zahteva.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54353104P | 2004-02-11 | 2004-02-11 | |
GB0403037A GB2410947B (en) | 2004-02-11 | 2004-02-11 | Pharmaceutical compounds |
PCT/GB2005/000464 WO2005077946A1 (en) | 2004-02-11 | 2005-02-11 | Dihydrotetrabenazines and pharmaceutical compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
RS50660B true RS50660B (sr) | 2010-06-30 |
Family
ID=32011732
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RSP-2008/0550A RS50660B (sr) | 2004-02-11 | 2005-02-11 | Dihidrotetrabenazini i farmaceutske kompozicije koje ih sadrže |
Country Status (23)
Country | Link |
---|---|
US (1) | US20080108645A1 (sr) |
EP (1) | EP1716145B1 (sr) |
JP (1) | JP2007522193A (sr) |
CN (1) | CN100591680C (sr) |
AT (1) | ATE406370T1 (sr) |
AU (1) | AU2005213525B2 (sr) |
CA (1) | CA2555815A1 (sr) |
CY (1) | CY1108592T1 (sr) |
DE (1) | DE602005009327D1 (sr) |
DK (1) | DK1716145T3 (sr) |
ES (1) | ES2313292T3 (sr) |
GB (1) | GB2410947B (sr) |
HK (1) | HK1098138A1 (sr) |
HR (1) | HRP20080564T3 (sr) |
MX (1) | MXPA06009164A (sr) |
NZ (1) | NZ549105A (sr) |
PL (1) | PL1716145T3 (sr) |
PT (1) | PT1716145E (sr) |
RS (1) | RS50660B (sr) |
RU (1) | RU2365590C2 (sr) |
SI (1) | SI1716145T1 (sr) |
WO (1) | WO2005077946A1 (sr) |
ZA (1) | ZA200607425B (sr) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2843590B1 (fr) | 2002-08-14 | 2007-10-05 | Prestwick Scient Capital Inc | Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique |
GB0514501D0 (en) * | 2005-07-14 | 2005-08-24 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
GB0516168D0 (en) * | 2005-08-05 | 2005-09-14 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
RS50807B (sr) * | 2005-08-06 | 2010-08-31 | Biovail Laboratories International (Barbados) Srl. | 3,11 b-cis-dihidrotetrabenazin za lečenje šizofrenije i drugih psihoza |
EP2012833B1 (en) * | 2006-05-02 | 2014-10-29 | The Trustees Of The University Of Pennsylvania | Radiolabeled dihydrotrabenazine derivatives and their use as imaging agents |
US8039627B2 (en) * | 2006-11-08 | 2011-10-18 | Neurocrine Biosciences, Inc. | Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-A]isoquinolin-2-ol compounds and methods relating thereto |
WO2009055520A2 (en) * | 2007-10-25 | 2009-04-30 | General Electric Company | Fluorinated dihydrotetrabenazine ether imaging agents and probes |
US7897769B2 (en) | 2007-10-25 | 2011-03-01 | General Electric Company | Intermediates for fluorinated dihydrotetrabenazine ether imaging agents and probes |
US7897770B2 (en) | 2007-10-25 | 2011-03-01 | General Electric Company | Fluorinated dihydrotetrabenazine ether imaging agents and probes |
GB0721669D0 (en) * | 2007-11-02 | 2007-12-12 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
US7910738B2 (en) | 2007-11-29 | 2011-03-22 | General Electric Company | Intermediates for alpha-fluoroalkyl tetrabenazine and dihydrotetrabenazine imaging agents and probes |
US7902364B2 (en) | 2007-11-29 | 2011-03-08 | General Electric Company | Alpha-fluoroalkyl tetrabenazine and dihydrotetrabenazine imaging agents and probes |
US8053578B2 (en) * | 2007-11-29 | 2011-11-08 | General Electric Company | Alpha-fluoroalkyl dihydrotetrabenazine imaging agents and probes |
US8013161B1 (en) | 2007-12-07 | 2011-09-06 | General Electric Company | Fluoroalkyl tetrabenazine carbinol compounds as imaging agents and probes |
US7919622B2 (en) | 2007-12-07 | 2011-04-05 | Kande Kankanamalage Dayarathna Amarasinghe | Intermediates for fluorinated tetrabenazine carbinol compounds imaging agents and probes |
CN101889013B (zh) * | 2007-12-07 | 2014-09-03 | 通用电气公司 | 作为成像剂和探针的氟烷基丁苯那嗪甲醇化合物 |
GB0810857D0 (en) * | 2008-06-13 | 2008-07-23 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
US20110053866A1 (en) * | 2008-08-12 | 2011-03-03 | Biovail Laboratories International (Barbados) S.R.L. | Pharmaceutical compositions |
GB2462611A (en) * | 2008-08-12 | 2010-02-17 | Cambridge Lab | Pharmaceutical composition comprising tetrabenazine |
US20120208773A1 (en) * | 2008-08-12 | 2012-08-16 | Valeant International (Barbados) Srl | Pharmaceutical compositions with tetrabenazine |
GB2463283A (en) * | 2008-09-08 | 2010-03-10 | Cambridge Lab | 3,11b-cis-dihydrotetrabenazine for use in treating asthma |
GB2463452A (en) * | 2008-09-08 | 2010-03-17 | Cambridge Lab | Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof |
GB2463451A (en) | 2008-09-08 | 2010-03-17 | Cambridge Lab | 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia |
EP3345905B1 (en) | 2008-09-18 | 2021-09-01 | Auspex Pharmaceuticals, Inc. | Deuterated benzoquinolizine derivatives as inhibitors of vesicular monoamine transporter 2 |
CA2771539A1 (en) | 2009-08-12 | 2011-02-17 | Valeant International (Barbados) Srl | Pharmaceutical compositions with tetrabenzine |
CN104744456A (zh) | 2010-06-01 | 2015-07-01 | 奥斯拜客斯制药有限公司 | Vmat2的苯并喹啉酮抑制剂 |
CN102285984B (zh) * | 2010-11-25 | 2012-10-10 | 江苏威凯尔医药科技有限公司 | (2R,3R,11bR)-二氢丁苯那嗪及相关化合物的制备方法 |
IN2015DN01662A (sr) | 2012-09-18 | 2015-07-03 | Auspex Pharmaceuticals Inc | |
US9550780B2 (en) | 2012-09-18 | 2017-01-24 | Auspex Pharmaceuticals, Inc. | Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2 |
EP2951178A4 (en) | 2013-01-31 | 2016-07-06 | Auspex Pharmaceuticals Inc | VMAT2 INHIBITORS OF BENZOQUINOLONE TYPE |
EP3424504A1 (en) | 2013-12-03 | 2019-01-09 | Auspex Pharmaceuticals, Inc. | Methods of manufacturing benzoquinoline compounds |
EP3099299A4 (en) | 2014-01-27 | 2017-10-04 | Auspex Pharmaceuticals, Inc. | Benzoquinoline inhibitors of vesicular monoamine transporter 2 |
EP3102239A1 (en) | 2014-02-07 | 2016-12-14 | Neurocrine Biosciences, Inc. | Pharmaceutical compositions comprising an antipsychotic drug and a vmat2 inhibitor and uses thereof |
EP3102190A4 (en) | 2014-02-07 | 2017-09-06 | Auspex Pharmaceuticals, Inc. | Novel pharmaceutical formulations |
HUE059747T2 (hu) * | 2015-03-06 | 2022-12-28 | Auspex Pharmaceuticals Inc | Eljárások rendellenes, akaratlan mozgással járó zavarok kezelésére |
JP6919099B2 (ja) | 2015-06-23 | 2021-08-18 | ニューロクライン バイオサイエンシーズ,インコーポレイテッド | 神経学的疾患または障害を処置するためのvmat2阻害剤 |
CN115304596A (zh) | 2015-10-30 | 2022-11-08 | 纽罗克里生物科学有限公司 | Valbenazine盐及其多晶形物 |
DK3394057T3 (da) * | 2015-12-23 | 2022-04-11 | Neurocrine Biosciences Inc | Syntetisk fremgangsmåde til fremstilling af (S)-(2R,3R,11BR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11B-hexahydro-1H-pyrido[2,1,-A]isoquinolin-2-yl 2-amino-3-methylbutanoat-di(4-methylbenzensulfonat) |
US20200078352A1 (en) | 2016-12-02 | 2020-03-12 | Neurocrine Biosciences, Inc. | Use of Valbenazine for Treating Schizophrenia or Schizoaffective Disorder |
WO2018140095A2 (en) * | 2017-01-27 | 2018-08-02 | Obrien Christopher F | Methods for the administration of certain vmat2 inhibitors |
WO2018164996A1 (en) | 2017-03-06 | 2018-09-13 | Neurocrine Biosciences, Inc. | Dosing regimen for valbenazine |
GB201705304D0 (en) | 2017-04-01 | 2017-05-17 | Adeptio Pharmaceuticals Ltd | Pharmaceutical compositions |
RU2022104034A (ru) | 2017-04-01 | 2022-03-05 | Адептио Фармасьютикалз Лимитед | Фармацевтические композиции |
GB201705306D0 (en) | 2017-04-01 | 2017-05-17 | Adeptio Pharmaceuticals Ltd | Pharmaceutical compositions |
GB201705303D0 (en) | 2017-04-01 | 2017-05-17 | Adeptio Pharmaceuticals Ltd | Pharmaceutical compositions |
GB201705302D0 (en) | 2017-04-01 | 2017-05-17 | Adeptio Pharmaceuticals Ltd | Pharmaceutical compositions |
JP2020512986A (ja) * | 2017-04-01 | 2020-04-30 | アデプティオ ファーマシューティカルズ リミテッド | 運動障害の治療に使用するための(+)−α−ジヒドロテトラベナジン |
WO2018200605A1 (en) | 2017-04-26 | 2018-11-01 | Neurocrine Biosciences, Inc. | Use of valbenazine for treating levodopa-induced dyskinesia |
CN107089980B (zh) * | 2017-05-11 | 2019-08-30 | 合肥工业大学 | 一种手性苯并[a]喹嗪-2-酮类化合物及其不对称催化合成方法 |
IL309802A (en) | 2017-09-21 | 2024-02-01 | Neurocrine Biosciences Inc | High dosage valbenazine formulation and compositions, methods, and kits related thereto |
US10993941B2 (en) | 2017-10-10 | 2021-05-04 | Neurocrine Biosciences, Inc. | Methods for the administration of certain VMAT2 inhibitors |
US20200230127A1 (en) * | 2017-10-10 | 2020-07-23 | Neurocrine Biosciences, Inc. | Methods for the Administration of Certain VMAT2 Inhibitors |
US12144899B2 (en) | 2018-04-25 | 2024-11-19 | Shinkei Therapeutics, Inc. | Tetrabenazine transdermal delivery device |
GB201808464D0 (en) | 2018-05-23 | 2018-07-11 | Adeptio Pharmaceuticals Ltd | Pharmaceutical compounds for use in treating huntington's disease |
JOP20200298A1 (ar) | 2018-06-14 | 2020-11-22 | Neurocrine Biosciences Inc | مركبات مثبطة لـ vmat2 وتركيبات وطرق تتعلق بها |
WO2020037022A1 (en) | 2018-08-15 | 2020-02-20 | Neurocrine Biosciences, Inc. | Methods for the administration of certain vmat2 inhibitors |
US10940141B1 (en) | 2019-08-23 | 2021-03-09 | Neurocrine Biosciences, Inc. | Methods for the administration of certain VMAT2 inhibitors |
JP2024511053A (ja) | 2021-03-22 | 2024-03-12 | ニューロクライン バイオサイエンシーズ,インコーポレイテッド | Vmat2阻害剤および使用方法 |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3314966A (en) * | 1967-04-18 | Substituted benzo[a]quinolizines | ||
US3009918A (en) * | 1961-11-21 | Chz ch | ||
US3159638A (en) * | 1964-12-01 | Xcha-chj | ||
US3053845A (en) * | 1962-09-11 | Benzofykedocolines | ||
US3132147A (en) * | 1964-05-05 | |||
US3079395A (en) * | 1963-02-26 | Novel z-oxq-benzoquinoliaine | ||
US3123609A (en) * | 1964-03-03 | Benzo | ||
US2830993A (en) * | 1958-04-15 | Quinolizine derivatives | ||
US3209005A (en) * | 1965-09-28 | Hexahydro-llbh-benzo[a] quinolizines and processes therefor | ||
US2843591A (en) * | 1958-07-15 | Method for preparing same | ||
US3095419A (en) * | 1963-06-25 | Process for preparing z-oxo-j- | ||
US2954382A (en) * | 1960-09-27 | Xpreparation of hexahydrobenzoquinol- | ||
US3045021A (en) * | 1959-09-24 | 1962-07-17 | Hoffmann La Roche | Preparation of substituted 2-oxobenzoquinolizines |
GB999092A (en) * | 1959-11-24 | 1965-07-21 | Wellcome Found | Method for making benzo(a)-quinolizine derivatives |
US3375254A (en) * | 1961-09-29 | 1968-03-26 | Burroughs Wellcome Co | Manufacture of 1, 2, 3, 4, 6, 7-hexahydro-2-oxo-11bh-benzo(a)quinolizines |
US3105079A (en) * | 1961-12-29 | 1963-09-24 | Pfizer & Co C | 10-aminobenzopyridocolines |
US3390152A (en) * | 1965-10-21 | 1968-06-25 | Abbott Lab | 9, 10-alkoxy-3-alkyl-2, 2-(dithiosubstituted)-benzoquinolizines |
US3634431A (en) * | 1969-12-22 | 1972-01-11 | Miles Lab | Acylated and alkylated derivatives of 2-aminohexahydrobenzo(a)quinolizines |
US3635986A (en) * | 1969-12-22 | 1972-01-18 | Miles Lab | 2-substituted amino-hexahydrobenzo(a)quinolizines |
YU264675A (en) * | 1974-10-23 | 1982-05-31 | Chinoin Gyogyszer Es Vegyeszet | Process for obtaining benzo (a)-quinolizidine derivatives |
GB1513824A (en) * | 1975-05-22 | 1978-06-14 | Wyeth John & Brother Ltd | 1,3,4,6,7,11b-hexahydro-2h-benzo(a)quinolizine derivative |
US4133812A (en) * | 1975-11-21 | 1979-01-09 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | Process for producing benzo (a) quinolizine derivatives |
US4304913A (en) * | 1978-11-20 | 1981-12-08 | Miles Laboratories, Inc. | Trans-2-substituted-amido-hexahydrobenzo [A]quinolizines |
US4353656A (en) * | 1980-10-14 | 1982-10-12 | Xerox Corporation | Moving coil, multiple energy print hammer system including a closed loop servo |
US4778054A (en) * | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
NL8601949A (nl) * | 1985-07-30 | 1987-02-16 | Glaxo Group Ltd | Inrichtingen voor het toedienen van medicamenten aan patienten. |
GB9004781D0 (en) * | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
US6087376A (en) * | 1997-02-05 | 2000-07-11 | University Of Kentucky Research Foundation | Use of lobeline compounds in the treatment of central nervous system diseases and pathologies |
FR2794742B1 (fr) * | 1999-06-11 | 2005-06-03 | Sanofi Synthelabo | Nouveaux derives du benzene, un procede pour leur preparation et les compositions pharmaceutiques les contenant |
US6632666B2 (en) * | 2000-01-14 | 2003-10-14 | Biolife Solutions, Inc. | Normothermic, hypothermic and cryopreservation maintenance and storage of cells, tissues and organs in gel-based media |
CA2398446A1 (en) * | 2000-04-18 | 2001-10-25 | Agouron Pharmaceuticals, Inc. | Pyrazoles for inhibiting protein kinases |
EP2529730A1 (en) * | 2003-06-16 | 2012-12-05 | ANDRX Pharmaceuticals LLC. | Oral sustained-release composition |
KR100682506B1 (ko) * | 2005-01-18 | 2007-02-15 | (주)젠크로스 | 프라지콴텔, 또는 이의 염을 포함하는 약학 조성물 |
GB0514501D0 (en) * | 2005-07-14 | 2005-08-24 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
GB0516168D0 (en) * | 2005-08-05 | 2005-09-14 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
GB0810857D0 (en) * | 2008-06-13 | 2008-07-23 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
GB2462611A (en) * | 2008-08-12 | 2010-02-17 | Cambridge Lab | Pharmaceutical composition comprising tetrabenazine |
US20110053866A1 (en) * | 2008-08-12 | 2011-03-03 | Biovail Laboratories International (Barbados) S.R.L. | Pharmaceutical compositions |
GB2463451A (en) * | 2008-09-08 | 2010-03-17 | Cambridge Lab | 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia |
GB2463283A (en) * | 2008-09-08 | 2010-03-10 | Cambridge Lab | 3,11b-cis-dihydrotetrabenazine for use in treating asthma |
GB2463452A (en) * | 2008-09-08 | 2010-03-17 | Cambridge Lab | Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof |
-
2004
- 2004-02-11 GB GB0403037A patent/GB2410947B/en not_active Expired - Fee Related
-
2005
- 2005-02-11 AU AU2005213525A patent/AU2005213525B2/en not_active Ceased
- 2005-02-11 JP JP2006552683A patent/JP2007522193A/ja active Pending
- 2005-02-11 RS RSP-2008/0550A patent/RS50660B/sr unknown
- 2005-02-11 NZ NZ549105A patent/NZ549105A/en not_active IP Right Cessation
- 2005-02-11 CN CN200580012044A patent/CN100591680C/zh not_active Expired - Fee Related
- 2005-02-11 WO PCT/GB2005/000464 patent/WO2005077946A1/en active Application Filing
- 2005-02-11 ZA ZA200607425A patent/ZA200607425B/xx unknown
- 2005-02-11 MX MXPA06009164A patent/MXPA06009164A/es active IP Right Grant
- 2005-02-11 SI SI200530470T patent/SI1716145T1/sl unknown
- 2005-02-11 DE DE602005009327T patent/DE602005009327D1/de not_active Expired - Lifetime
- 2005-02-11 US US10/597,803 patent/US20080108645A1/en not_active Abandoned
- 2005-02-11 DK DK05708289T patent/DK1716145T3/da active
- 2005-02-11 PL PL05708289T patent/PL1716145T3/pl unknown
- 2005-02-11 CA CA002555815A patent/CA2555815A1/en not_active Abandoned
- 2005-02-11 RU RU2006132329/04A patent/RU2365590C2/ru not_active IP Right Cessation
- 2005-02-11 EP EP05708289A patent/EP1716145B1/en not_active Expired - Lifetime
- 2005-02-11 PT PT05708289T patent/PT1716145E/pt unknown
- 2005-02-11 ES ES05708289T patent/ES2313292T3/es not_active Expired - Lifetime
- 2005-02-11 AT AT05708289T patent/ATE406370T1/de active
-
2007
- 2007-04-25 HK HK07104428.7A patent/HK1098138A1/xx not_active IP Right Cessation
-
2008
- 2008-11-06 HR HR20080564T patent/HRP20080564T3/xx unknown
- 2008-11-26 CY CY20081101360T patent/CY1108592T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
PT1716145E (pt) | 2008-11-14 |
EP1716145B1 (en) | 2008-08-27 |
AU2005213525A1 (en) | 2005-08-25 |
CY1108592T1 (el) | 2014-04-09 |
EP1716145A1 (en) | 2006-11-02 |
DE602005009327D1 (de) | 2008-10-09 |
AU2005213525B2 (en) | 2011-01-06 |
NZ549105A (en) | 2009-04-30 |
RU2006132329A (ru) | 2008-03-20 |
ATE406370T1 (de) | 2008-09-15 |
GB2410947B (en) | 2008-09-17 |
RU2365590C2 (ru) | 2009-08-27 |
GB0403037D0 (en) | 2004-03-17 |
WO2005077946A1 (en) | 2005-08-25 |
HRP20080564T3 (en) | 2009-02-28 |
GB2410947A (en) | 2005-08-17 |
JP2007522193A (ja) | 2007-08-09 |
CN100591680C (zh) | 2010-02-24 |
PL1716145T3 (pl) | 2009-04-30 |
MXPA06009164A (es) | 2007-01-26 |
US20080108645A1 (en) | 2008-05-08 |
CA2555815A1 (en) | 2005-08-25 |
SI1716145T1 (sl) | 2009-02-28 |
CN1980924A (zh) | 2007-06-13 |
DK1716145T3 (da) | 2008-11-10 |
HK1098138A1 (en) | 2007-07-13 |
ZA200607425B (en) | 2008-02-27 |
ES2313292T3 (es) | 2009-03-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RS50660B (sr) | Dihidrotetrabenazini i farmaceutske kompozicije koje ih sadrže | |
HRP20070374T3 (en) | Formulations comprising ecteinascidin and a disaccharide | |
LTC1608344I2 (lt) | Per burną vartojamos kladribino kompozicijos | |
TW200732349A (en) | Anti-OX40L antibodies and methods using same | |
NO20052306D0 (no) | Dispergerbare farmasoytiske blandinger. | |
ATE289640T1 (de) | Amidofunktionelle aminopolydiorganosiloxane | |
DE602005010109D1 (de) | 1,1a,5,5a-tetrahydro-3-thia-cyclopropaäaüpentaleneptor-agonisten | |
SE0301653D0 (sv) | Novel compounds | |
HUS1500006I1 (hu) | Benzotiazol-származék vegyületek, kompozíciók és alkalmazások | |
MX2008001597A (es) | Formulaciones novedosas que comprenden fenofibrato y una estatina y metodos relacionados de tratamiento. | |
ATE506362T1 (de) | 1-aza-bicycloä3.3.1ünonane | |
NO20063293L (no) | Farmasoytiske forbindelser | |
SE0301650D0 (sv) | Novel compounds | |
ITMI20030385A1 (it) | Composizione cosmetica comprendente poliisoprene. | |
ITRM20030363A0 (it) | Composizioni comprendenti la 3, 5diiodotironina e uso farmaceutico diesse. | |
TW200621160A (en) | Anti-termite agent | |
RS51534B (sr) | Novi spoj inihbitora sinusoidne if struje i kalcijumskog inhibitora i farmaceutske smeše koje ga sadrže | |
BRPI0313645A2 (pt) | composições de inalação com relações de droga elevadas. | |
NO20052478D0 (no) | Vitamin D-analoger, sammensetninger omfattende analogene og deres anvendelse. | |
BRPI0500536A (pt) | Composição antimicrobiana | |
MX2007007355A (es) | 5-(2,2-dimetil-ciclopropil)-3-metil-pen-2-en nitrilo como fragancia y sabor. | |
ITTO20020747A1 (it) | Composizione. | |
NL1025908A1 (nl) | Farmaceutische combinatie. | |
GEP20084546B (en) | Novel association consisting of an anti-atherothrombotic agent and of platelet antiaggregating agent | |
BRPI0410638A (pt) | derivados de azitromicina |