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SG11202009441PA - Treatment of hidradenitis suppurativa using jak inhibitors - Google Patents

Treatment of hidradenitis suppurativa using jak inhibitors

Info

Publication number
SG11202009441PA
SG11202009441PA SG11202009441PA SG11202009441PA SG11202009441PA SG 11202009441P A SG11202009441P A SG 11202009441PA SG 11202009441P A SG11202009441P A SG 11202009441PA SG 11202009441P A SG11202009441P A SG 11202009441PA SG 11202009441P A SG11202009441P A SG 11202009441PA
Authority
SG
Singapore
Prior art keywords
treatment
jak inhibitors
hidradenitis suppurativa
suppurativa
hidradenitis
Prior art date
Application number
SG11202009441PA
Other languages
English (en)
Inventor
Michael D Howell
Paul Smith
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=66429533&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11202009441P(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of SG11202009441PA publication Critical patent/SG11202009441PA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11202009441PA 2018-03-30 2019-03-29 Treatment of hidradenitis suppurativa using jak inhibitors SG11202009441PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862650600P 2018-03-30 2018-03-30
PCT/US2019/024998 WO2019191684A1 (fr) 2018-03-30 2019-03-29 Traitement de l'hidradénite suppurée à l'aide d'inhibiteurs de jak

Publications (1)

Publication Number Publication Date
SG11202009441PA true SG11202009441PA (en) 2020-10-29

Family

ID=66429533

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202009441PA SG11202009441PA (en) 2018-03-30 2019-03-29 Treatment of hidradenitis suppurativa using jak inhibitors

Country Status (34)

Country Link
US (2) US11304949B2 (fr)
EP (2) EP4424328A3 (fr)
JP (2) JP2021519775A (fr)
KR (1) KR20210018203A (fr)
CN (3) CN113768927A (fr)
AU (2) AU2019245420B2 (fr)
BR (1) BR112020019814A2 (fr)
CA (1) CA3095487A1 (fr)
CL (1) CL2020002512A1 (fr)
CO (1) CO2020013600A2 (fr)
DK (1) DK3773593T3 (fr)
EA (1) EA202092343A1 (fr)
EC (1) ECSP20069416A (fr)
ES (1) ES2980497T3 (fr)
FI (1) FI3773593T3 (fr)
HR (1) HRP20240741T1 (fr)
HU (1) HUE067471T2 (fr)
IL (3) IL318069A (fr)
LT (1) LT3773593T (fr)
MA (1) MA52219B1 (fr)
MD (1) MD3773593T2 (fr)
MX (2) MX2022012285A (fr)
PE (1) PE20210402A1 (fr)
PH (1) PH12020551597A1 (fr)
PL (1) PL3773593T3 (fr)
PT (1) PT3773593T (fr)
RS (1) RS65624B1 (fr)
SG (1) SG11202009441PA (fr)
SI (1) SI3773593T1 (fr)
SM (1) SMT202400306T1 (fr)
TW (2) TW202310843A (fr)
UA (1) UA127925C2 (fr)
WO (1) WO2019191684A1 (fr)
ZA (1) ZA202202361B (fr)

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JP6359546B2 (ja) * 2012-11-01 2018-07-18 インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ Ｊａｋ阻害薬としての三環式縮合チオフェン誘導体
IL276725B2 (en) 2018-02-16 2024-09-01 Incyte Corp Jak1 pathway inhibitors for the treatment of cytokine-related disorders
PE20210402A1 (es) 2018-03-30 2021-03-02 Incyte Corp Tratamiento de la hidradenitis supurativa mediante el uso de inhibidores de jak
EP3775284A1 (fr) 2018-03-30 2021-02-17 Incyte Corporation Biomarqueurs pour maladie cutanée inflammatoire
US11372003B2 (en) 2018-04-13 2022-06-28 Incyte Corporation Biomarkers for graft-versus-host disease
CA3117969A1 (fr) 2018-10-31 2020-05-07 Incyte Corporation Polytherapie pour le traitement de maladies hematologiques
WO2020165788A1 (fr) * 2019-02-15 2020-08-20 Pfizer Inc. Composé de pyrimidinyl-3,8-diazabicyclo [3.2.1] octanylméthanone cristallin et son utilisation
EA202192426A1 (ru) 2019-03-05 2021-11-15 Инсайт Корпорейшн Ингибиторы путей jak1 для лечения хронической дисфункции аллотрансплантата легких
CN114667148A (zh) * 2019-09-11 2022-06-24 辉瑞公司 用jak抑制剂治疗汗腺炎
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WO2021072098A1 (fr) 2019-10-10 2021-04-15 Incyte Corporation Biomarqueurs de la maladie du greffon contre l'hôte
US11992490B2 (en) 2019-10-16 2024-05-28 Incyte Corporation Use of JAK1 inhibitors for the treatment of cutaneous lupus erythematosus and Lichen planus (LP)
WO2022125670A1 (fr) 2020-12-08 2022-06-16 Incyte Corporation Inhibiteurs de la voie jak1 destinés au traitement du vitiligo
IL308216A (en) 2021-05-03 2024-01-01 Incyte Corp Jak1 pathway inhibitors for the treatment of prurigo nodularis
CN117186078A (zh) * 2023-11-06 2023-12-08 药康众拓(北京)医药科技有限公司 氘代氮杂环丁烷类jak抑制剂药物及用途
WO2025117642A1 (fr) * 2023-12-01 2025-06-05 Incyte Corporation Ruxolitinib pour le traitement de l'hidrosadénite suppurée (hs)

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