SG11201708194WA - Fusion proteins - Google Patents
Fusion proteinsInfo
- Publication number
- SG11201708194WA SG11201708194WA SG11201708194WA SG11201708194WA SG11201708194WA SG 11201708194W A SG11201708194W A SG 11201708194WA SG 11201708194W A SG11201708194W A SG 11201708194WA SG 11201708194W A SG11201708194W A SG 11201708194WA SG 11201708194W A SG11201708194W A SG 11201708194WA
- Authority
- SG
- Singapore
- Prior art keywords
- fusion proteins
- fusion
- proteins
- Prior art date
Links
- 102000037865 fusion proteins Human genes 0.000 title 1
- 108020001507 fusion proteins Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562158079P | 2015-05-07 | 2015-05-07 | |
PCT/US2016/029807 WO2016178905A1 (en) | 2015-05-07 | 2016-04-28 | Fusion proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201708194WA true SG11201708194WA (en) | 2017-11-29 |
Family
ID=55953435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201708194WA SG11201708194WA (en) | 2015-05-07 | 2016-04-28 | Fusion proteins |
Country Status (40)
Country | Link |
---|---|
US (5) | US9855318B2 (zh) |
EP (1) | EP3292141B1 (zh) |
JP (1) | JP6591562B2 (zh) |
KR (1) | KR102059736B1 (zh) |
CN (1) | CN107531806B (zh) |
AR (1) | AR105616A1 (zh) |
AU (1) | AU2016257659B2 (zh) |
CA (1) | CA2981102A1 (zh) |
CL (1) | CL2017002761A1 (zh) |
CO (1) | CO2017011301A2 (zh) |
CR (1) | CR20170469A (zh) |
CY (1) | CY1122929T1 (zh) |
DK (1) | DK3292141T3 (zh) |
DO (1) | DOP2017000258A (zh) |
EA (1) | EA039770B1 (zh) |
EC (1) | ECSP17073650A (zh) |
ES (1) | ES2799099T3 (zh) |
HR (1) | HRP20200503T1 (zh) |
IL (1) | IL254965B (zh) |
JO (1) | JO3658B1 (zh) |
LT (1) | LT3292141T (zh) |
MA (1) | MA42037B1 (zh) |
MD (1) | MD3292141T2 (zh) |
ME (1) | ME03709B (zh) |
MX (1) | MX388594B (zh) |
MY (1) | MY183025A (zh) |
NZ (1) | NZ736470A (zh) |
PE (1) | PE20180507A1 (zh) |
PH (1) | PH12017502025B1 (zh) |
PL (1) | PL3292141T3 (zh) |
PT (1) | PT3292141T (zh) |
RS (1) | RS60044B1 (zh) |
SG (1) | SG11201708194WA (zh) |
SI (1) | SI3292141T1 (zh) |
SV (1) | SV2017005548A (zh) |
TN (1) | TN2018000059A1 (zh) |
TW (1) | TWI656132B (zh) |
UA (1) | UA122146C2 (zh) |
WO (1) | WO2016178905A1 (zh) |
ZA (1) | ZA201706334B (zh) |
Families Citing this family (37)
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US11208452B2 (en) | 2015-06-02 | 2021-12-28 | Novo Nordisk A/S | Insulins with polar recombinant extensions |
MA43348A (fr) | 2015-10-01 | 2018-08-08 | Novo Nordisk As | Conjugués de protéines |
KR102233545B1 (ko) | 2016-07-27 | 2021-03-29 | 휴렛-팩커드 디벨롭먼트 컴퍼니, 엘.피. | 디지털 유체 레벨 센서를 갖는 유체 공급 카트리지용 수평 인터페이스 |
HRP20211334T1 (hr) * | 2016-12-09 | 2021-11-26 | Akston Biosciences Corporation | Inzulin-fc fuzije i načini uporabe |
TR201703622A1 (tr) * | 2017-03-09 | 2018-09-21 | Univ Yeditepe | Obezi̇te tedavi̇si̇ i̇çi̇n bi̇r ürün |
JP2020513019A (ja) * | 2017-04-05 | 2020-04-30 | ノヴォ ノルディスク アー/エス | オリゴマー伸長インスリン−Fcコンジュゲート |
TWI835773B (zh) * | 2018-01-26 | 2024-03-21 | 美商建南德克公司 | 組合物及使用方法 |
EP3810640A1 (en) | 2018-06-25 | 2021-04-28 | University of Washington | De novo design of potent and selective interleukin mimetics |
US11267862B2 (en) | 2018-06-29 | 2022-03-08 | Akston Biosciences Corporation | Ultra-long acting insulin-Fc fusion proteins and methods of use |
HUE065725T2 (hu) * | 2018-06-29 | 2024-06-28 | Akston Biosciences Corp | Ultra-hosszú hatású inzulin-FC fúziós fehérjék és alkalmazási eljárások |
WO2020074544A1 (en) | 2018-10-10 | 2020-04-16 | Novo Nordisk A/S | Oligomer extended insulin-fc conjugates and their medical use |
EP3883956A1 (en) | 2018-11-20 | 2021-09-29 | University of Washington | Split interleukin mimetics and their use |
WO2020190591A1 (en) * | 2019-03-15 | 2020-09-24 | Eli Lilly And Company | Preserved formulations |
WO2021011827A1 (en) * | 2019-07-16 | 2021-01-21 | Akston Biosciences Corporation | Ultra-long acting insulin-fc fusion proteins and methods of use |
TWI844709B (zh) | 2019-07-31 | 2024-06-11 | 美商美國禮來大藥廠 | 鬆弛素(relaxin)類似物及其使用方法 |
MX2022004311A (es) | 2019-10-15 | 2022-05-10 | Lilly Co Eli | Estirpes celulares de mamiferos con deficiencia de lipasa/esterasa modificadas geneticamente de manera recombinante. |
EP4073098B1 (en) * | 2019-12-19 | 2023-09-27 | Akston Biosciences Corporation | Ultra-long acting insulin-fc fusion proteins and methods of use |
US11186623B2 (en) | 2019-12-24 | 2021-11-30 | Akston Bioscience Corporation | Ultra-long acting insulin-Fc fusion proteins and methods of use |
WO2021188374A2 (en) | 2020-03-16 | 2021-09-23 | Neoleukin Therapeutics, Inc. | Interleukin-2 receptor βeta (il-2rβ) binding polypeptides |
JP2023521706A (ja) | 2020-04-07 | 2023-05-25 | ネオロイキン セラピューティクス, インコーポレイテッド | アンギオテンシン変換酵素2(ace2)のデノボタンパク質デコイ |
US11192930B2 (en) | 2020-04-10 | 2021-12-07 | Askton Bioscences Corporation | Ultra-long acting insulin-Fc fusion protein and methods of use |
BR112022020486A2 (pt) | 2020-04-10 | 2023-01-17 | Akston Biosciences Corp | Imunoterapia específica de antígeno para proteínas de fusão de covid-19 e métodos de uso |
US11198719B2 (en) | 2020-04-29 | 2021-12-14 | Akston Biosciences Corporation | Ultra-long acting insulin-Fc fusion protein and methods of use |
US20230272030A1 (en) * | 2020-07-24 | 2023-08-31 | Jiangsu Gensciences Inc. | Insulin-fc fusion protein and application thereof |
CN116723852A (zh) * | 2020-12-14 | 2023-09-08 | 伊莱利利公司 | 治疗糖尿病的方法 |
US11667689B2 (en) | 2021-07-23 | 2023-06-06 | Akston Biosciences Corporation | Insulin-Fc fusion proteins and methods of use to treat cancer |
WO2023044318A2 (en) | 2021-09-15 | 2023-03-23 | Neoleukin Therapeutics, Inc. | Interleukin-2 receptor βeta (il-2rβ) binding polypeptides |
TWI871539B (zh) | 2021-11-15 | 2025-02-01 | 美商美國禮來大藥廠 | 可保存之調配物 |
EP4495143A1 (en) * | 2022-03-16 | 2025-01-22 | Beijing Tuo Jie Biopharmaceutical Co. Ltd. | Human insulin analogue, and fusion protein thereof and medical use thereof |
KR20250004935A (ko) | 2022-05-18 | 2025-01-08 | 프로토머 테크놀로지스 인크. | 방향족 붕소-함유 화합물 및 관련 인슐린 유사체 |
CN119403824A (zh) | 2022-06-23 | 2025-02-07 | 赛诺菲 | 单链胰岛素及其Fc缀合物 |
WO2024137820A1 (en) * | 2022-12-20 | 2024-06-27 | The Board Of Trustees Of The Leland Stanford Junior University | Insulin receptor antagonist |
CN115894720B (zh) * | 2023-01-16 | 2024-07-09 | 中国科学院上海药物研究所 | 一种长效胰岛素-Fc融合蛋白 |
WO2024229093A1 (en) | 2023-05-03 | 2024-11-07 | Eli Lilly And Company | Methods and systems for managing diabetes |
WO2025059010A1 (en) | 2023-09-11 | 2025-03-20 | Eli Lilly And Company | Methods and systems for managing diabetes |
WO2025061146A1 (zh) * | 2023-09-20 | 2025-03-27 | 上海迈晋生物医药科技有限公司 | 一种人胰岛素类似物融合蛋白的药物组合物及其医药用途 |
WO2025080923A1 (en) | 2023-10-13 | 2025-04-17 | Eli Lilly And Company | Insulin-fc fusion proteins |
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KR102049647B1 (ko) | 2014-11-21 | 2019-11-29 | 머크 샤프 앤드 돔 코포레이션 | 인슐린 수용체 부분 효능제 |
WO2016133372A2 (ko) | 2015-02-17 | 2016-08-25 | 한미약품 주식회사 | 지속형 인슐린 또는 이의 아날로그 결합체 |
CN110134210A (zh) | 2019-04-16 | 2019-08-16 | 深圳市国鑫恒宇科技有限公司 | 一种服务器一体机的温度控制方法、系统、装置及存储介质 |
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2016
- 2016-04-20 AR ARP160101082A patent/AR105616A1/es unknown
- 2016-04-21 JO JOP/2016/0076A patent/JO3658B1/ar active
- 2016-04-22 TW TW105112730A patent/TWI656132B/zh active
- 2016-04-28 PT PT167216050T patent/PT3292141T/pt unknown
- 2016-04-28 AU AU2016257659A patent/AU2016257659B2/en active Active
- 2016-04-28 NZ NZ736470A patent/NZ736470A/en unknown
- 2016-04-28 SG SG11201708194WA patent/SG11201708194WA/en unknown
- 2016-04-28 HR HRP20200503TT patent/HRP20200503T1/hr unknown
- 2016-04-28 PL PL16721605T patent/PL3292141T3/pl unknown
- 2016-04-28 MX MX2017014284A patent/MX388594B/es unknown
- 2016-04-28 MD MDE20180255T patent/MD3292141T2/ro unknown
- 2016-04-28 KR KR1020177031825A patent/KR102059736B1/ko active Active
- 2016-04-28 MA MA42037A patent/MA42037B1/fr unknown
- 2016-04-28 CN CN201680023998.4A patent/CN107531806B/zh active Active
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