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SG11201708194WA - Fusion proteins - Google Patents

Fusion proteins

Info

Publication number
SG11201708194WA
SG11201708194WA SG11201708194WA SG11201708194WA SG11201708194WA SG 11201708194W A SG11201708194W A SG 11201708194WA SG 11201708194W A SG11201708194W A SG 11201708194WA SG 11201708194W A SG11201708194W A SG 11201708194WA SG 11201708194W A SG11201708194W A SG 11201708194WA
Authority
SG
Singapore
Prior art keywords
fusion proteins
fusion
proteins
Prior art date
Application number
SG11201708194WA
Inventor
David Bruce Baldwin
John Michael Beals
Jonathan Wesley Day
Craig Duane Dickinson
Andrew Ihor Korytko
Gregory Alan Lazar
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55953435&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201708194W(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SG11201708194WA publication Critical patent/SG11201708194WA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
SG11201708194WA 2015-05-07 2016-04-28 Fusion proteins SG11201708194WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562158079P 2015-05-07 2015-05-07
PCT/US2016/029807 WO2016178905A1 (en) 2015-05-07 2016-04-28 Fusion proteins

Publications (1)

Publication Number Publication Date
SG11201708194WA true SG11201708194WA (en) 2017-11-29

Family

ID=55953435

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201708194WA SG11201708194WA (en) 2015-05-07 2016-04-28 Fusion proteins

Country Status (40)

Country Link
US (5) US9855318B2 (en)
EP (1) EP3292141B1 (en)
JP (1) JP6591562B2 (en)
KR (1) KR102059736B1 (en)
CN (1) CN107531806B (en)
AR (1) AR105616A1 (en)
AU (1) AU2016257659B2 (en)
CA (1) CA2981102A1 (en)
CL (1) CL2017002761A1 (en)
CO (1) CO2017011301A2 (en)
CR (1) CR20170469A (en)
CY (1) CY1122929T1 (en)
DK (1) DK3292141T3 (en)
DO (1) DOP2017000258A (en)
EA (1) EA039770B1 (en)
EC (1) ECSP17073650A (en)
ES (1) ES2799099T3 (en)
HR (1) HRP20200503T1 (en)
IL (1) IL254965B (en)
JO (1) JO3658B1 (en)
LT (1) LT3292141T (en)
MA (1) MA42037B1 (en)
MD (1) MD3292141T2 (en)
ME (1) ME03709B (en)
MX (1) MX388594B (en)
MY (1) MY183025A (en)
NZ (1) NZ736470A (en)
PE (1) PE20180507A1 (en)
PH (1) PH12017502025B1 (en)
PL (1) PL3292141T3 (en)
PT (1) PT3292141T (en)
RS (1) RS60044B1 (en)
SG (1) SG11201708194WA (en)
SI (1) SI3292141T1 (en)
SV (1) SV2017005548A (en)
TN (1) TN2018000059A1 (en)
TW (1) TWI656132B (en)
UA (1) UA122146C2 (en)
WO (1) WO2016178905A1 (en)
ZA (1) ZA201706334B (en)

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US11267862B2 (en) 2018-06-29 2022-03-08 Akston Biosciences Corporation Ultra-long acting insulin-Fc fusion proteins and methods of use
HUE065725T2 (en) * 2018-06-29 2024-06-28 Akston Biosciences Corp Ultra-long-acting insulin-FC fusion proteins and methods of use
WO2020074544A1 (en) 2018-10-10 2020-04-16 Novo Nordisk A/S Oligomer extended insulin-fc conjugates and their medical use
EP3883956A1 (en) 2018-11-20 2021-09-29 University of Washington Split interleukin mimetics and their use
WO2020190591A1 (en) * 2019-03-15 2020-09-24 Eli Lilly And Company Preserved formulations
WO2021011827A1 (en) * 2019-07-16 2021-01-21 Akston Biosciences Corporation Ultra-long acting insulin-fc fusion proteins and methods of use
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EP4073098B1 (en) * 2019-12-19 2023-09-27 Akston Biosciences Corporation Ultra-long acting insulin-fc fusion proteins and methods of use
US11186623B2 (en) 2019-12-24 2021-11-30 Akston Bioscience Corporation Ultra-long acting insulin-Fc fusion proteins and methods of use
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JP2023521706A (en) 2020-04-07 2023-05-25 ネオロイキン セラピューティクス， インコーポレイテッド Angiotensin-converting enzyme 2 (ACE2) de novo protein decoy
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BR112022020486A2 (en) 2020-04-10 2023-01-17 Akston Biosciences Corp ANTIGEN-SPECIFIC IMMUNOTHERAPY FOR COVID-19 FUSION PROTEINS AND METHODS OF USE
US11198719B2 (en) 2020-04-29 2021-12-14 Akston Biosciences Corporation Ultra-long acting insulin-Fc fusion protein and methods of use
US20230272030A1 (en) * 2020-07-24 2023-08-31 Jiangsu Gensciences Inc. Insulin-fc fusion protein and application thereof
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EP4495143A1 (en) * 2022-03-16 2025-01-22 Beijing Tuo Jie Biopharmaceutical Co. Ltd. Human insulin analogue, and fusion protein thereof and medical use thereof
KR20250004935A (en) 2022-05-18 2025-01-08 프로토머 테크놀로지스 인크. Aromatic boron-containing compounds and related insulin analogs
CN119403824A (en) 2022-06-23 2025-02-07 赛诺菲 Single-chain insulin and its Fc conjugate
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CN115894720B (en) * 2023-01-16 2024-07-09 中国科学院上海药物研究所 Long-acting insulin-Fc fusion protein
WO2024229093A1 (en) 2023-05-03 2024-11-07 Eli Lilly And Company Methods and systems for managing diabetes
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WO2025061146A1 (en) * 2023-09-20 2025-03-27 上海迈晋生物医药科技有限公司 Pharmaceutical composition containing human insulin analogue fusion protein and medical use thereof
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Also Published As

Publication number Publication date
KR102059736B1 (en) 2019-12-26
PH12017502025A1 (en) 2018-04-02
US20160324932A1 (en) 2016-11-10
HK1244019A1 (en) 2018-07-27
NZ736470A (en) 2019-04-26
JP6591562B2 (en) 2019-10-16
CO2017011301A2 (en) 2018-03-20
US20220211818A1 (en) 2022-07-07
DK3292141T3 (en) 2020-04-20
CL2017002761A1 (en) 2018-05-18
CN107531806A (en) 2018-01-02
SV2017005548A (en) 2018-04-24
ZA201706334B (en) 2020-01-29
EP3292141B1 (en) 2020-02-12
US20200390865A1 (en) 2020-12-17
MA42037B1 (en) 2020-03-31
US11253574B2 (en) 2022-02-22
US12059452B2 (en) 2024-08-13
TW201712029A (en) 2017-04-01
CN107531806B (en) 2022-06-07
PT3292141T (en) 2020-04-22
WO2016178905A1 (en) 2016-11-10
ME03709B (en) 2021-01-20
JP2018515088A (en) 2018-06-14
BR112017020502A2 (en) 2018-07-03
TWI656132B (en) 2019-04-11
MD3292141T2 (en) 2020-07-31
US20180177851A1 (en) 2018-06-28
TN2018000059A1 (en) 2019-07-08
US20250032588A1 (en) 2025-01-30
DOP2017000258A (en) 2017-12-31
ECSP17073650A (en) 2018-02-28
EA039770B1 (en) 2022-03-11
RS60044B1 (en) 2020-04-30
AU2016257659A1 (en) 2017-10-12
JO3658B1 (en) 2020-08-27
PE20180507A1 (en) 2018-03-09
IL254965B (en) 2021-03-25
HRP20200503T1 (en) 2020-06-26
MX388594B (en) 2025-03-20
KR20170134614A (en) 2017-12-06
IL254965A0 (en) 2017-12-31
LT3292141T (en) 2020-03-25
MX2017014284A (en) 2018-03-23
US9855318B2 (en) 2018-01-02
CA2981102A1 (en) 2016-11-10
SI3292141T1 (en) 2020-04-30
CY1122929T1 (en) 2021-10-29
PH12017502025B1 (en) 2018-04-02
AU2016257659B2 (en) 2018-08-09
AR105616A1 (en) 2017-10-25
MY183025A (en) 2021-02-07
EP3292141A1 (en) 2018-03-14
EA201792199A1 (en) 2018-03-30
UA122146C2 (en) 2020-09-25
US10709766B2 (en) 2020-07-14
PL3292141T3 (en) 2020-06-29
CR20170469A (en) 2017-11-14
ES2799099T3 (en) 2020-12-14

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