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RS60124B1 - Upotreba alginatnih oligomera kao antikoagulanasa krvi - Google Patents

Upotreba alginatnih oligomera kao antikoagulanasa krvi

Info

Publication number
RS60124B1
RS60124B1 RS20200384A RSP20200384A RS60124B1 RS 60124 B1 RS60124 B1 RS 60124B1 RS 20200384 A RS20200384 A RS 20200384A RS P20200384 A RSP20200384 A RS P20200384A RS 60124 B1 RS60124 B1 RS 60124B1
Authority
RS
Serbia
Prior art keywords
alginate oligomers
blood anticoagulants
anticoagulants
blood
oligomers
Prior art date
Application number
RS20200384A
Other languages
English (en)
Inventor
Arne Dessen
Philip Rye
Original Assignee
Algipharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Algipharma As filed Critical Algipharma As
Publication of RS60124B1 publication Critical patent/RS60124B1/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/734—Alginic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06—Use of macromolecular materials
    • A61L33/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3672—Means preventing coagulation
    • A61M1/3673—Anticoagulant coating, e.g. Heparin coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/04—Alginic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RS20200384A 2013-12-20 2014-12-19 Upotreba alginatnih oligomera kao antikoagulanasa krvi RS60124B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1322777.2A GB201322777D0 (en) 2013-12-20 2013-12-20 Use of alginate oligomers as blood anticoagulants
PCT/GB2014/053808 WO2015092437A1 (en) 2013-12-20 2014-12-19 Use of alginate oligomers as blood anticoagulants
EP14815848.8A EP3082830B1 (en) 2013-12-20 2014-12-19 Use of alginate oligomers as blood anticoagulants

Publications (1)

Publication Number Publication Date
RS60124B1 true RS60124B1 (sr) 2020-05-29

Family

ID=50071308

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20200384A RS60124B1 (sr) 2013-12-20 2014-12-19 Upotreba alginatnih oligomera kao antikoagulanasa krvi

Country Status (18)

Country Link
US (1) US11712448B2 (sr)
EP (1) EP3082830B1 (sr)
JP (1) JP6626824B2 (sr)
KR (1) KR102256919B1 (sr)
CN (1) CN105960243B (sr)
AU (1) AU2014369463B2 (sr)
BR (1) BR112016014321A8 (sr)
CA (1) CA2934572C (sr)
DK (1) DK3082830T3 (sr)
ES (1) ES2779228T3 (sr)
GB (1) GB201322777D0 (sr)
HU (1) HUE048891T2 (sr)
PL (1) PL3082830T3 (sr)
PT (1) PT3082830T (sr)
RS (1) RS60124B1 (sr)
RU (1) RU2709814C1 (sr)
SI (1) SI3082830T1 (sr)
WO (1) WO2015092437A1 (sr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10017471B2 (en) * 2015-04-21 2018-07-10 University Of Tennessee Research Foundation Selective androgen receptor degrader (SARD) ligands and methods of use thereof
US11072668B2 (en) 2017-01-03 2021-07-27 The University Of North Carolina At Chapel Hill Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto
CA3055474A1 (en) 2017-03-28 2018-10-04 The University Of North Carolina At Chapel Hill Nitric oxide-releasing polyaminoglycosides as biodegradable antibacterial scaffolds and methods pertaining thereto
CA3091458A1 (en) 2018-03-06 2019-09-12 The University Of North Carolina At Chapel Hill Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto
AU2019414421B2 (en) 2018-12-28 2023-08-31 The University Of North Carolina At Chapel Hill Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto
GB201908639D0 (en) 2019-06-17 2019-07-31 Algipharma Ipr As Use of alginate oligomers in the anticoagulation therapy of subjects at risk of blood clots which have an abnormally dense microstructure

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2508433A (en) * 1946-10-16 1950-05-23 Wyeth Corp Alginic acid sulfate anticoagulant
EP0059221A4 (en) * 1980-09-03 1983-08-16 Kyosei Pharmaceutical Co Ltd CONNECTION FOR THE FOOD CHANNEL.
US5135955A (en) * 1988-04-25 1992-08-04 Eli Lilly And Company Propanamine derivatives
KR920000459B1 (ko) 1989-12-13 1992-01-14 재단법인 한국화학연구소 다당류 유도체가 도포된 인공혈관과 그 제조방법
GB9221163D0 (en) 1992-10-08 1992-11-25 Nobipol And Protan Biopolymer Dna compounds
US5646130A (en) 1995-06-30 1997-07-08 Ocean University Of Oingdao Low molecular weight sulfated polysaccharides and uses thereof
NO305033B1 (no) 1997-05-09 1999-03-22 Algipharma As Fremgangsmate for fremstilling av uronsyreblokker fra alginat
US7494669B2 (en) 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
NO20023581D0 (no) 2002-07-26 2002-07-26 Fmc Biopolymer As Nye mutantstammer av Pseudomonas fluorescens og varianter derav, metoder for produksjon og bruk derav til produksjon avalginat
CN1218965C (zh) 2003-11-04 2005-09-14 武汉大学 海藻酸钠硫酸酯及其制备方法和用途
GB2430881B (en) 2005-10-06 2010-10-13 Ntnu Technology Transfer As Oligoelectrolyte polyols for the treatment of mucosal hyperviscosity
AU2007333377B2 (en) 2006-12-08 2014-01-16 Millennium Pharmaceuticals, Inc. Unit dose formulations and methods of treating thrombosis with an oral factor Xa inhibitor
GB0707096D0 (en) 2007-04-12 2007-05-23 Ntnu Technology Transfer As Method
DK2268142T3 (en) * 2007-11-27 2017-05-22 Algipharma As USING ALGINATED OLIGOMERS TO FIGHT BIOFILM
US9295716B2 (en) 2008-02-22 2016-03-29 Annexin Pharmaceuticals Ab Methods for treating restenosis using annexin A5
EP2437784B8 (en) 2009-06-03 2013-12-11 Algipharma As Alginate oligomers for use in overcoming multidrug resistance in bacteria
KR101229055B1 (ko) * 2010-06-07 2013-02-04 신라대학교 산학협력단 알긴산 분해능을 갖는 메틸로박테리움 속 균주 및 상기 균주를 이용한 알긴산 올리고머 제조방법
CN102212148B (zh) 2011-03-21 2013-07-17 中国海洋大学 一种静脉注射用抗血栓药及其制备方法和应用
CN102382204B (zh) 2011-08-31 2013-06-26 中国海洋大学 低分子量藻酸双酯钠及其制备方法和应用
CN103142539B (zh) 2013-03-21 2014-08-20 青岛正大海尔制药有限公司 一种藻酸双酯钠控释片及其制备方法

Also Published As

Publication number Publication date
ES2779228T3 (es) 2020-08-14
DK3082830T3 (da) 2020-03-30
CN105960243A (zh) 2016-09-21
JP6626824B2 (ja) 2019-12-25
EP3082830B1 (en) 2020-03-04
KR20160099707A (ko) 2016-08-22
GB201322777D0 (en) 2014-02-05
BR112016014321A2 (sr) 2017-08-08
BR112016014321A8 (pt) 2020-06-02
JP2017508716A (ja) 2017-03-30
AU2014369463B2 (en) 2020-02-27
US11712448B2 (en) 2023-08-01
KR102256919B1 (ko) 2021-05-27
CA2934572A1 (en) 2015-06-25
CN105960243B (zh) 2020-01-14
SI3082830T1 (sl) 2020-07-31
EP3082830A1 (en) 2016-10-26
RU2016126848A (ru) 2018-01-25
PT3082830T (pt) 2020-04-08
PL3082830T3 (pl) 2020-06-29
WO2015092437A1 (en) 2015-06-25
CA2934572C (en) 2023-08-15
AU2014369463A1 (en) 2016-07-14
RU2709814C1 (ru) 2019-12-23
US20160331777A1 (en) 2016-11-17
HUE048891T2 (hu) 2020-08-28

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