PT1864679E - Aperfeiçoamento em vesículas de membrana externa bacterianas - Google Patents
Aperfeiçoamento em vesículas de membrana externa bacterianas Download PDFInfo
- Publication number
- PT1864679E PT1864679E PT70128939T PT07012893T PT1864679E PT 1864679 E PT1864679 E PT 1864679E PT 70128939 T PT70128939 T PT 70128939T PT 07012893 T PT07012893 T PT 07012893T PT 1864679 E PT1864679 E PT 1864679E
- Authority
- PT
- Portugal
- Prior art keywords
- pellet
- outer membrane
- membrane vesicles
- collecting
- detergent
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/06—Lysis of microorganisms
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0220194.5A GB0220194D0 (en) | 2002-08-30 | 2002-08-30 | Improved vesicles |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1864679E true PT1864679E (pt) | 2014-09-25 |
Family
ID=9943238
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT70128939T PT1864679E (pt) | 2002-08-30 | 2003-09-01 | Aperfeiçoamento em vesículas de membrana externa bacterianas |
PT03791150T PT1534326E (pt) | 2002-08-30 | 2003-09-01 | Aperfeiçoamentos em vesículas de membrana externa bacterianas |
PT101797835T PT2258389E (pt) | 2002-08-30 | 2003-09-01 | Vesículas de membrana externa bacteriana melhorada |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT03791150T PT1534326E (pt) | 2002-08-30 | 2003-09-01 | Aperfeiçoamentos em vesículas de membrana externa bacterianas |
PT101797835T PT2258389E (pt) | 2002-08-30 | 2003-09-01 | Vesículas de membrana externa bacteriana melhorada |
Country Status (21)
Country | Link |
---|---|
US (2) | US20060166344A1 (pt) |
EP (5) | EP2258388B1 (pt) |
JP (3) | JP2006503822A (pt) |
CN (2) | CN1688334A (pt) |
AT (1) | ATE366117T1 (pt) |
AU (1) | AU2003263534B2 (pt) |
BR (1) | BRPI0314094A8 (pt) |
CA (1) | CA2497165C (pt) |
CY (3) | CY1107737T1 (pt) |
DE (1) | DE60314756T2 (pt) |
DK (3) | DK1864679T3 (pt) |
ES (4) | ES2289351T3 (pt) |
FR (1) | FR13C0046I2 (pt) |
GB (1) | GB0220194D0 (pt) |
LU (1) | LU92239I2 (pt) |
MX (1) | MXPA05002316A (pt) |
NZ (1) | NZ538673A (pt) |
PT (3) | PT1864679E (pt) |
RU (1) | RU2325184C2 (pt) |
SI (2) | SI1864679T1 (pt) |
WO (1) | WO2004019977A2 (pt) |
Families Citing this family (84)
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PT1047784E (pt) * | 1998-01-14 | 2009-12-21 | Novartis Vaccines & Diagnostic | Antigénios de neisseria meningitidis |
JP5074644B2 (ja) | 1998-05-29 | 2012-11-14 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | 組合わせの髄膜炎菌b/cワクチン |
AU783894B2 (en) | 1999-05-19 | 2005-12-22 | Novartis Vaccines And Diagnostics S.R.L. | Combination neisserial compositions |
GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
US8273360B2 (en) | 2000-01-17 | 2012-09-25 | Novartis Ag | Outer membrane vesicle (OMV) vaccine comprising N. meningitidis serogroup B outer membrane proteins |
EP1322328B1 (en) | 2000-07-27 | 2014-08-20 | Children's Hospital & Research Center at Oakland | Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis |
MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
CU23377A1 (es) * | 2003-11-04 | 2009-05-28 | Ct De Ingenieria Genetica Y Biotecnologia | Metodo para la incorporacion de antigenos en vesiculas de membrana externa de bacterias y formulaciones resultantes |
GB0416120D0 (en) | 2004-07-19 | 2004-08-18 | Health Prot Agency | Stable compositions containing OMV's |
US8029777B2 (en) * | 2004-08-13 | 2011-10-04 | Marshall Barry J | Helicobacter system and uses thereof |
CN102078622A (zh) | 2004-08-13 | 2011-06-01 | 巴里.J.马沙尔 | 细菌递送系统 |
GB0419627D0 (en) * | 2004-09-03 | 2004-10-06 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
PT2682126T (pt) | 2005-01-27 | 2017-02-28 | Children`S Hospital & Res Center At Oakland | Vacinas de vesícula com base em agn1870 para proteção de amplo espetro contra doenças causadas por neisseria meningitidis |
CN101203529A (zh) * | 2005-02-18 | 2008-06-18 | 诺华疫苗和诊断公司 | 来自脑膜炎/脓毒症相关性大肠杆菌的蛋白质和核酸 |
WO2006123164A2 (en) * | 2005-05-19 | 2006-11-23 | The Edward Jenner Institute For Vaccine Research | Lps-binding and bactericidal cytokines and interferons |
PT1896061T (pt) | 2005-06-27 | 2019-08-01 | Glaxosmithkline Biologicals Sa | Composição imunogénica |
GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
AU2016204760A1 (en) * | 2006-04-26 | 2016-07-28 | Wyeth Llc | Novel formulations which stabilize and inhibit precipitation of immunogenic compositions |
AU2014268186C1 (en) * | 2006-04-26 | 2017-12-07 | Wyeth Llc | Novel formulations which stabilize and inhibit precipitation of immunogenic compositions |
AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
ATE553774T1 (de) | 2007-10-19 | 2012-05-15 | Novartis Ag | Meningokokkenimpfstoffformulierungen |
EP3263591B1 (en) | 2008-02-21 | 2019-03-27 | GlaxoSmithKline Biologicals S.A. | Meningococcal fhbp polypeptides |
GB0819633D0 (en) * | 2008-10-25 | 2008-12-03 | Isis Innovation | Composition |
GB0822634D0 (en) | 2008-12-11 | 2009-01-21 | Novartis Ag | Meningitis vaccines |
US20100189737A1 (en) | 2008-12-17 | 2010-07-29 | Arico Beatrice | Meningococcal vaccines including hemoglobin receptor |
WO2010109323A1 (en) | 2009-03-24 | 2010-09-30 | Novartis Ag | Adjuvanting meningococcal factor h binding protein |
WO2010127172A2 (en) * | 2009-04-30 | 2010-11-04 | Children's Hospital & Research Center At Oakland | Chimeric factor h binding proteins (fhbp) and methods of use |
ES2658863T3 (es) | 2009-06-10 | 2018-03-12 | Glaxosmithkline Biologicals Sa | Vacunas que contienen benzonaftiridina |
US20110045528A1 (en) * | 2009-08-20 | 2011-02-24 | Srisuda Dhamwichukorn | Apparatus and method for enhanced disruption and extraction of intracellular materials from microbial cells |
ES2562259T3 (es) | 2009-08-27 | 2016-03-03 | Glaxosmithkline Biologicals Sa | Polipéptidos híbridos que incluyen secuencias fHBP meningocócicas |
JP2013503148A (ja) | 2009-08-27 | 2013-01-31 | ノバルティス アーゲー | アルミニウム、オリゴヌクレオチドおよびポリカチオンを含むアジュバント |
WO2011027956A2 (ko) | 2009-09-04 | 2011-03-10 | 주식회사이언메딕스 | 그람 양성 박테리아에서 유래한 세포밖 소포체 및 이를 이용한 질병 모델 |
KR101430283B1 (ko) | 2009-09-01 | 2014-08-14 | 주식회사이언메딕스 | 장내 공생 세균유래 세포밖 소포체, 및 이를 이용한 질병모델, 백신, 후보 약물 탐색 방법, 및 진단 방법 |
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