NO20022238L - Polycykloalkyl-puriner som adenosinreseptor-antagonister - Google Patents

Polycykloalkyl-puriner som adenosinreseptor-antagonister

Info

Publication number: NO20022238L
Authority: NO; Norway
Prior art keywords: polycycloalkyl; purines; receptor antagonists; adenosine receptor; adenosine
Prior art date: 1999-11-12

Application number

NO20022238A

Other languages

English (en)

Other versions

NO20022238D0 (no

NO328956B1 (no

Inventor

William F Kiesman

James E Dowling

Carol L Ensinger

Gnanasambandam Kumaravel

Russell C Petter

He Xi Chang

Ko Chung Lin

Original Assignee

Biogen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-11-12

Filing date

2002-05-10

Publication date

2002-07-12

2002-05-10 Application filed by Biogen Inc filed Critical Biogen Inc

2002-05-10 Publication of NO20022238D0 publication Critical patent/NO20022238D0/no

2002-07-12 Publication of NO20022238L publication Critical patent/NO20022238L/no

2010-06-28 Publication of NO328956B1 publication Critical patent/NO328956B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/22—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one sulfur atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Gastroenterology & Hepatology (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Vascular Medicine (AREA)
Dermatology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO20022238A 1999-11-12 2002-05-10 Adenosinreseptorantagonist NO328956B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US16519199P	1999-11-12	1999-11-12
PCT/US2000/031058 WO2001034610A1 (en)	1999-11-12	2000-11-13	Polycycloalkylpurines as adenosine receptor antagonists

Publications (3)

Publication Number	Publication Date
NO20022238D0 NO20022238D0 (no)	2002-05-10
NO20022238L true NO20022238L (no)	2002-07-12
NO328956B1 NO328956B1 (no)	2010-06-28

Family

ID=22597852

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20022238A NO328956B1 (no)	1999-11-12	2002-05-10	Adenosinreseptorantagonist

Country Status (35)

Country	Link
US (5)	US6649600B1 (no)
EP (3)	EP1230243B1 (no)
JP (1)	JP2003513982A (no)
KR (2)	KR20080027971A (no)
CN (2)	CN100390178C (no)
AT (1)	ATE424403T1 (no)
AU (1)	AU784556B2 (no)
BG (1)	BG65720B1 (no)
BR (1)	BR0015545A (no)
CA (1)	CA2390496A1 (no)
CY (1)	CY1110512T1 (no)
CZ (1)	CZ20021614A3 (no)
DE (1)	DE60041710D1 (no)
DK (1)	DK1230243T3 (no)
EA (1)	EA005211B1 (no)
EE (1)	EE05365B1 (no)
ES (1)	ES2323357T3 (no)
GE (1)	GEP20043303B (no)
HK (1)	HK1049155B (no)
IL (1)	IL149487A0 (no)
IS (1)	IS6379A (no)
ME (1)	MEP42208A (no)
MX (1)	MXPA02004796A (no)
NO (1)	NO328956B1 (no)
NZ (2)	NZ527917A (no)
PL (1)	PL206890B1 (no)
PT (1)	PT1230243E (no)
RS (1)	RS50381B (no)
SI (1)	SI1230243T1 (no)
SK (1)	SK287311B6 (no)
TR (1)	TR200201260T2 (no)
TW (1)	TWI272270B (no)
UA (1)	UA77391C2 (no)
WO (1)	WO2001034610A1 (no)
ZA (1)	ZA200203701B (no)

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DE10145193C1 (de)	2001-09-13	2003-03-13	Sachtler Gmbh & Co Kg	Körpermontierbares Kameratragesystem mit einem multifunktionalen Verbund elektrischer Komponenten
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EP1521584A1 (en)	2002-06-17	2005-04-13	Glaxo Group Limited	Purine derivatives as liver x receptor agonists
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JP2006518390A (ja) *	2003-02-19	2006-08-10	エンダシア，インコーポレイテッド	Ａ１アデノシンレセプターアンタゴニスト
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JP4859666B2 (ja)	2003-06-06	2012-01-25	エンダセア，インコーポレイテッド	Ａ１アデノシンレセプターアンタゴニスト
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WO2011063268A2 (en)	2009-11-19	2011-05-26	Biogen Idec Ma Inc	Novel synthetic methods
EP3121208A1 (en) *	2009-12-04	2017-01-25	Commonwealth Scientific and Industrial Research Organisation	Polymeric materials
CN101709034B (zh) *	2009-12-14	2017-05-31	大连九信精细化工有限公司	双环[2.2.2]辛烷‑1，4‑二羧酸单甲酯的合成方法
TWI538905B (zh) *	2010-12-22	2016-06-21	Ｈ朗德貝克公司	雙環［３．２．１］辛基醯胺衍生物及其用途
US20140243302A1 (en)	2011-06-27	2014-08-28	Merck Sharp & Dohme Corporation	Bridged bicyclic compounds for the treatment of bacterial infections
US8962660B2 (en)	2013-03-14	2015-02-24	Bristol-Myers Squibb Company	Oxabicyclo [2.2.2] acid GPR120 modulators
JP2016516708A (ja) *	2013-03-14	2016-06-09	ブリストル−マイヤーズスクイブカンパニーＢｒｉｓｔｏｌ−ＭｙｅｒｓＳｑｕｉｂｂＣｏｍｐａｎｙ	ビシクロ［２．２．２］酸のｇｐｒ１２０モジュレーター
LT6401B (lt)	2015-07-28	2017-06-12	Vilniaus Universitetas	Karboanhidrazės selektyvūs inhibitoriai
AU2017208970A1 (en)	2016-01-18	2018-08-02	Arisan Therapeutics	Adamatane derivatives for the treatment of filovirus infection
US10633315B2 (en)	2016-10-19	2020-04-28	Eastman Chemical Company	Synthesis of bicyclo[2.2.2]octanes
WO2019018185A1 (en)	2017-07-15	2019-01-24	Arisan Therapeutics Inc.	ENANTIOMERICALLY PURE ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTIONS
MX2020002944A (es)	2017-09-14	2020-09-28	Daiichi Sankyo Co Ltd	Compuesto que tiene estructura ciclica.
WO2019075004A1 (en)	2017-10-11	2019-04-18	Eastman Chemical Company	SYNTHESIS OF BICYCLO [2.2.2] OCTANE DERIVATIVES
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HUP0203371A3 (en) *	1999-11-12	2005-02-28	Biogen Idec Ma Inc Cambridge	Adenosine receptor antagonists and methods of making and using the same
US7074798B2 (en)	2002-02-25	2006-07-11	Eisai Co., Ltd	Xanthine derivative and DPPIV inhibitor
WO2004009594A2 (en) *	2002-07-19	2004-01-29	Aryx Therapeutics	Xanthine derivatives having adenosine a1-receptor antagonist properties
US7129239B2 (en)	2002-10-28	2006-10-31	Pfizer Inc.	Purine compounds and uses thereof
DK1781657T3 (da) *	2004-02-14	2013-06-10	Glaxosmithkline Ip Dev Ltd	Medikamenter med hm74a-receptor aktivitet

2000
- 2000-11-13 SI SI200031029T patent/SI1230243T1/sl unknown
- 2000-11-13 NZ NZ527917A patent/NZ527917A/en not_active IP Right Cessation
- 2000-11-13 UA UA2002064822A patent/UA77391C2/uk unknown
- 2000-11-13 CA CA002390496A patent/CA2390496A1/en not_active Abandoned
- 2000-11-13 AU AU16000/01A patent/AU784556B2/en not_active Ceased
- 2000-11-13 DK DK00978546T patent/DK1230243T3/da active
- 2000-11-13 MX MXPA02004796A patent/MXPA02004796A/es active IP Right Grant
- 2000-11-13 IL IL14948700A patent/IL149487A0/xx not_active IP Right Cessation
- 2000-11-13 NZ NZ519426A patent/NZ519426A/en not_active IP Right Cessation
- 2000-11-13 CN CNB008164398A patent/CN100390178C/zh not_active Expired - Fee Related
- 2000-11-13 CN CNA2008100921415A patent/CN101255162A/zh active Pending
- 2000-11-13 WO PCT/US2000/031058 patent/WO2001034610A1/en active IP Right Grant
- 2000-11-13 EA EA200200560A patent/EA005211B1/ru not_active IP Right Cessation
- 2000-11-13 BR BR0015545-4A patent/BR0015545A/pt not_active Application Discontinuation
- 2000-11-13 DE DE60041710T patent/DE60041710D1/de not_active Expired - Lifetime
- 2000-11-13 RS YUP-338/02A patent/RS50381B/sr unknown
- 2000-11-13 AT AT00978546T patent/ATE424403T1/de active
- 2000-11-13 TR TR2002/01260T patent/TR200201260T2/xx unknown
- 2000-11-13 KR KR1020087005528A patent/KR20080027971A/ko not_active Application Discontinuation
- 2000-11-13 EP EP00978546A patent/EP1230243B1/en not_active Expired - Lifetime
- 2000-11-13 EE EEP200200247A patent/EE05365B1/xx not_active IP Right Cessation
- 2000-11-13 ES ES00978546T patent/ES2323357T3/es not_active Expired - Lifetime
- 2000-11-13 PT PT00978546T patent/PT1230243E/pt unknown
- 2000-11-13 ME MEP-422/08A patent/MEP42208A/xx unknown
- 2000-11-13 US US09/711,543 patent/US6649600B1/en not_active Expired - Fee Related
- 2000-11-13 JP JP2001537323A patent/JP2003513982A/ja active Pending
- 2000-11-13 EP EP10183076A patent/EP2305684A1/en not_active Withdrawn
- 2000-11-13 KR KR1020027006093A patent/KR100863761B1/ko not_active IP Right Cessation
- 2000-11-13 EP EP09151275A patent/EP2070930A1/en not_active Withdrawn
- 2000-11-13 SK SK663-2002A patent/SK287311B6/sk not_active IP Right Cessation
- 2000-11-13 GE GE4819A patent/GEP20043303B/en unknown
- 2000-11-13 PL PL356033A patent/PL206890B1/pl not_active IP Right Cessation
- 2000-11-13 CZ CZ20021614A patent/CZ20021614A3/cs unknown
- 2000-12-15 TW TW089123845A patent/TWI272270B/zh active
2002
- 2002-05-09 ZA ZA200203701A patent/ZA200203701B/xx unknown
- 2002-05-10 NO NO20022238A patent/NO328956B1/no not_active IP Right Cessation
- 2002-05-10 IS IS6379A patent/IS6379A/is unknown
- 2002-05-31 BG BG106762A patent/BG65720B1/bg unknown
- 2002-12-23 HK HK02109310.2A patent/HK1049155B/zh not_active IP Right Cessation
2003
- 2003-08-21 US US10/646,454 patent/US20040067966A1/en not_active Abandoned
2006
- 2006-07-10 US US11/484,805 patent/US7579354B2/en not_active Expired - Fee Related
- 2006-07-13 US US11/487,764 patent/US20070015732A1/en not_active Abandoned
2009
- 2009-02-10 US US12/368,469 patent/US20090221821A1/en not_active Abandoned
- 2009-05-21 CY CY20091100543T patent/CY1110512T1/el unknown

Also Published As

Publication number	Publication date
KR20020049050A (ko)	2002-06-24
US20060252730A1 (en)	2006-11-09
HK1049155B (zh)	2009-11-06
ZA200203701B (en)	2004-02-23
EP1230243B1 (en)	2009-03-04
EE200200247A (et)	2003-06-16
PT1230243E (pt)	2009-06-12
NO20022238D0 (no)	2002-05-10
BR0015545A (pt)	2002-08-06
AU1600001A (en)	2001-06-06
WO2001034610A1 (en)	2001-05-17
CN1402729A (zh)	2003-03-12
DE60041710D1 (de)	2009-04-16
ATE424403T1 (de)	2009-03-15
UA77391C2 (en)	2006-12-15
NZ527917A (en)	2005-03-24
US6649600B1 (en)	2003-11-18
CN101255162A (zh)	2008-09-03
EE05365B1 (et)	2010-12-15
MXPA02004796A (es)	2007-01-30
KR100863761B1 (ko)	2008-10-16
SK287311B6 (sk)	2010-06-07
TR200201260T2 (tr)	2002-09-23
BG65720B1 (bg)	2009-08-31
NZ519426A (en)	2003-08-29
EP2305684A1 (en)	2011-04-06
HK1049155A1 (en)	2003-05-02
US20070015732A1 (en)	2007-01-18
AU784556B2 (en)	2006-05-04
IS6379A (is)	2002-05-10
US7579354B2 (en)	2009-08-25
TWI272270B (en)	2007-02-01
YU33802A (sh)	2006-01-16
RS50381B (sr)	2009-11-10
MEP42208A (en)	2011-02-10
CA2390496A1 (en)	2001-05-17
SI1230243T1 (sl)	2009-08-31
EA200200560A1 (ru)	2002-10-31
IL149487A0 (en)	2002-11-10
PL356033A1 (en)	2004-06-14
KR20080027971A (ko)	2008-03-28
PL206890B1 (pl)	2010-10-29
BG106762A (en)	2003-01-31
US20090221821A1 (en)	2009-09-03
CY1110512T1 (el)	2015-04-29
NO328956B1 (no)	2010-06-28
CN100390178C (zh)	2008-05-28
EP2070930A1 (en)	2009-06-17
GEP20043303B (en)	2004-01-12
EA005211B1 (ru)	2004-12-30
CZ20021614A3 (cs)	2002-07-17
JP2003513982A (ja)	2003-04-15
DK1230243T3 (da)	2009-06-15
SK6632002A3 (en)	2003-02-04
ES2323357T3 (es)	2009-07-14
US20040067966A1 (en)	2004-04-08
EP1230243A1 (en)	2002-08-14

Publication	Publication Date	Title
NO20022238L (no)	2002-07-12	Polycykloalkyl-puriner som adenosinreseptor-antagonister
CY1106560T1 (el)	2012-01-25	Ανταγωνιστες υποδοχεα αδενοσινης και μεθοδοι κατασκευης και χρησης αυτων
HK1083838A1 (en)	2006-07-14	A2a adenosine receptor antagonists
DK1551803T3 (da)	2007-02-19	Azabicycloderivater som muskarine receptorantagonister
DK0503563T3 (da)	2003-12-22	Hidtil ukendte 8-substituerede puriner som selektive adenosinreceptor-antagonister
DE69834500D1 (de)	2006-06-14	Xanthinderivative zur behandlung von hirnischämie
CA2275686A1 (en)	1998-06-25	Isoquinolinamine and phthalazinamine derivatives which interact with crf receptors
DK0896822T3 (da)	2003-06-02	4-aminopyrrol (3,2-d) pyrimidiner som neuropeptide Y receptorantagonister

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2012-06-25	MM1K	Lapsed by not paying the annual fees