ATE358484T1 - Antidiabetische medikamente - Google Patents
Antidiabetische medikamenteInfo
- Publication number
- ATE358484T1 ATE358484T1 AT99926903T AT99926903T ATE358484T1 AT E358484 T1 ATE358484 T1 AT E358484T1 AT 99926903 T AT99926903 T AT 99926903T AT 99926903 T AT99926903 T AT 99926903T AT E358484 T1 ATE358484 T1 AT E358484T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted
- group
- unsubstituted
- hydrogen atom
- lower alkyl
- Prior art date
Links
- 229940127003 anti-diabetic drug Drugs 0.000 title 1
- 239000003472 antidiabetic agent Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP18770598 | 1998-07-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE358484T1 true ATE358484T1 (de) | 2007-04-15 |
Family
ID=16210732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99926903T ATE358484T1 (de) | 1998-07-02 | 1999-07-02 | Antidiabetische medikamente |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6489331B1 (de) |
| EP (1) | EP1092435B1 (de) |
| AT (1) | ATE358484T1 (de) |
| AU (1) | AU4396899A (de) |
| CA (1) | CA2336412C (de) |
| DE (1) | DE69935718T2 (de) |
| ES (1) | ES2284256T3 (de) |
| WO (1) | WO2000001388A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1230243T1 (sl) | 1999-11-12 | 2009-08-31 | Biogen Idec Inc | Policikloalkilpurini kot antagonisti adenozinskega receptorja |
| HUP0203371A3 (en) | 1999-11-12 | 2005-02-28 | Biogen Idec Ma Inc Cambridge | Adenosine receptor antagonists and methods of making and using the same |
| CA2395414A1 (en) * | 1999-12-24 | 2001-07-05 | Kyowa Hakko Kogyo Co., Ltd | Condensed purine derivative |
| EP1347981B1 (de) | 2000-12-01 | 2008-05-07 | Biogen Idec MA Inc. | Kondensierte purinderivate als a1-adenosinrezeptorantagonisten |
| JP4450628B2 (ja) | 2002-03-22 | 2010-04-14 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ファルネシルトランスフェラーゼインヒビターとして使用するためのベンジルイミダゾリル置換２−キノリンおよびキナゾリン誘導体 |
| US20070191402A1 (en) * | 2002-05-17 | 2007-08-16 | Kyowa Hakko Kogyo Co., Ltd. | Method of searching substrate having antidiabetic activity |
| JPWO2003097064A1 (ja) * | 2002-05-17 | 2005-09-15 | 協和醗酵工業株式会社 | 糖尿病治療剤 |
| AU2003252697A1 (en) * | 2002-07-26 | 2004-02-16 | Kyowa Hakko Kogyo Co., Ltd. | Cell differentiation inductor |
| BR0314455A (pt) | 2002-09-19 | 2005-07-26 | Kyorin Seiyaku Kk | Derivados de aminoálcool, seus sais e agentes imunosupressores |
| CN1777608A (zh) * | 2003-04-25 | 2006-05-24 | 协和发酵工业株式会社 | 稠合嘧啶衍生物 |
| BRPI0513110A (pt) | 2004-07-16 | 2008-04-29 | Kyorin Seiyaku Kk | medicamento compreendendo composto sulfeto diaril ou composto éter diaril tendo uma estrutura 2-amina-1, 3-propanediol tendo uma atividade de redução de linfócitos perifericamente circulante, em combinação com um agente imunosupressivo e/ou um agente antiinflamatório e método de expressão de prevenção do efeito secundário |
| US7795472B2 (en) * | 2004-10-12 | 2010-09-14 | Kyorin Pharmaceutical Co., Ltd. | Process for producing 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]ethyl]-1,3-propanediol hydrochloride and hydrates thereof, and intermediates in the production thereof |
| CA2624909C (en) * | 2005-10-07 | 2013-10-01 | Kyorin Pharmaceutical Co., Ltd. | Therapeutic agent for treating liver disease containing 2-amino-1,3-propanediol derivative as active ingredient, and method for treating liver disease |
| TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
| TWI423978B (zh) * | 2006-06-23 | 2014-01-21 | Incyte Corp | 作為ｈｍ７４ａ同效劑之嘌呤酮衍生物（二） |
| ES2355325T3 (es) * | 2006-06-23 | 2011-03-24 | Incyte Corporation | Derivados de purinona como agonistas de hm74a. |
| KR20090025261A (ko) | 2006-06-23 | 2009-03-10 | 인사이트 코포레이션 | Ｈｍ７４ａ 아고니스트로서의 퓨리논 유도체 |
| MY152176A (en) * | 2006-08-08 | 2014-08-15 | Kyorin Seiyaku Kk | Amino phosphate derivative and s1p receptor modulator having same as an active ingredient |
| MY146775A (en) * | 2006-08-08 | 2012-09-28 | Kyorin Seiyaku Kk | Amino alcohol derivative and immunosuppressive agent having same as an active ingredient |
| JP4337898B2 (ja) * | 2007-03-29 | 2009-09-30 | セイコーエプソン株式会社 | 半導体装置 |
| WO2009099174A1 (ja) | 2008-02-07 | 2009-08-13 | Kyorin Pharmaceutical Co., Ltd. | アミノアルコール誘導体を有効成分とする炎症性腸疾患の治療剤又は予防剤 |
| EP2145621A1 (de) * | 2008-07-16 | 2010-01-20 | Stephan Lück | Verhinderung der Dehydrierung und Reduzierung der gluconeogenetischen Verluste von Aminosäuren durch Propan-1,2,3-Triol |
| CN103492359B (zh) * | 2011-04-02 | 2015-11-25 | 中国人民解放军军事医学科学院毒物药物研究所 | 氨基苯丙醇类化合物及其用于制备免疫抑制剂的用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5270316A (en) * | 1989-10-20 | 1993-12-14 | Kyowa Hakko Kogyo Co., Ltd. | Condensed purine derivatives |
| GB9015914D0 (en) * | 1990-07-19 | 1990-09-05 | Wellcome Found | Heterocyclic compounds |
| JP3204880B2 (ja) | 1995-07-25 | 2001-09-04 | 株式会社バーテックススタンダード | デジタルフィルタ |
| CA2239881A1 (en) * | 1996-10-07 | 1998-04-16 | Nobuo Kosaka | Condensed purine derivatives |
| JP4354016B2 (ja) | 1996-11-29 | 2009-10-28 | 株式会社メディサイエンスプラニング | 新規プリン誘導体およびこれを含む医薬組成物 |
-
1999
- 1999-07-02 AT AT99926903T patent/ATE358484T1/de not_active IP Right Cessation
- 1999-07-02 US US09/719,570 patent/US6489331B1/en not_active Expired - Fee Related
- 1999-07-02 EP EP99926903A patent/EP1092435B1/de not_active Expired - Lifetime
- 1999-07-02 CA CA002336412A patent/CA2336412C/en not_active Expired - Fee Related
- 1999-07-02 WO PCT/JP1999/003583 patent/WO2000001388A1/ja active IP Right Grant
- 1999-07-02 AU AU43968/99A patent/AU4396899A/en not_active Abandoned
- 1999-07-02 DE DE69935718T patent/DE69935718T2/de not_active Expired - Fee Related
- 1999-07-02 ES ES99926903T patent/ES2284256T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1092435A1 (de) | 2001-04-18 |
| CA2336412A1 (en) | 2000-01-13 |
| AU4396899A (en) | 2000-01-24 |
| US6489331B1 (en) | 2002-12-03 |
| EP1092435B1 (de) | 2007-04-04 |
| CA2336412C (en) | 2007-11-27 |
| DE69935718T2 (de) | 2007-12-27 |
| WO2000001388A1 (fr) | 2000-01-13 |
| DE69935718D1 (de) | 2007-05-16 |
| ES2284256T3 (es) | 2007-11-01 |
| EP1092435A4 (de) | 2004-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |