[go: up one dir, main page]

NO20004649D0 - Modulatorer av funksjonen av reseptorer av TNF/NGF- reseptorfamilien og andre proteiner - Google Patents

Modulatorer av funksjonen av reseptorer av TNF/NGF- reseptorfamilien og andre proteiner

Info

Publication number
NO20004649D0
NO20004649D0 NO20004649A NO20004649A NO20004649D0 NO 20004649 D0 NO20004649 D0 NO 20004649D0 NO 20004649 A NO20004649 A NO 20004649A NO 20004649 A NO20004649 A NO 20004649A NO 20004649 D0 NO20004649 D0 NO 20004649D0
Authority
NO
Norway
Prior art keywords
tnf
modulators
proteins
function
receptor family
Prior art date
Application number
NO20004649A
Other languages
English (en)
Other versions
NO327854B1 (no
NO20004649L (no
Inventor
David Wallach
Andrei Kovalenko
Marshall S Horwitz
Yongan Li
Original Assignee
Yeda Res & Dev
Einstein Coll Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL12375898A external-priority patent/IL123758A0/xx
Application filed by Yeda Res & Dev, Einstein Coll Med filed Critical Yeda Res & Dev
Publication of NO20004649D0 publication Critical patent/NO20004649D0/no
Publication of NO20004649L publication Critical patent/NO20004649L/no
Publication of NO327854B1 publication Critical patent/NO327854B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • AIDS & HIV (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20004649A 1998-03-19 2000-09-18 DNA-sekvens, replikerbar ekspresjonsvektor, transformert eukaryot eller prokaryot vertscelle; RAP-2 protein, isoform, fragment, funksjonell analog eller derivater derav samt fremgangsmate for fremstilling og anvendelse derav; farmasoytisk preparat, anvendelse av en rekombinant dyrevirusvektor og en vektor kodende for ribozym sekvens. NO327854B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IL12375898A IL123758A0 (en) 1998-03-19 1998-03-19 Modulators of the function of receptors of the TNF/NGF receptor family and other proteins
IL12602498A IL126024A0 (en) 1998-03-19 1998-09-01 Modulators of the function of receptors of the tnf/ngf receptor family and other proteins
PCT/IL1999/000158 WO1999047672A1 (en) 1998-03-19 1999-03-18 Modulators of the function of receptors of the tnf/ngf receptor family and other proteins
CA002323637A CA2323637A1 (en) 1998-03-19 1999-03-18 Modulators of the function of receptors of the tnf/ngf receptor family and other proteins

Publications (3)

Publication Number Publication Date
NO20004649D0 true NO20004649D0 (no) 2000-09-18
NO20004649L NO20004649L (no) 2000-10-30
NO327854B1 NO327854B1 (no) 2009-10-05

Family

ID=39598416

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004649A NO327854B1 (no) 1998-03-19 2000-09-18 DNA-sekvens, replikerbar ekspresjonsvektor, transformert eukaryot eller prokaryot vertscelle; RAP-2 protein, isoform, fragment, funksjonell analog eller derivater derav samt fremgangsmate for fremstilling og anvendelse derav; farmasoytisk preparat, anvendelse av en rekombinant dyrevirusvektor og en vektor kodende for ribozym sekvens.

Country Status (24)

Country Link
US (1) US6734174B1 (no)
EP (1) EP1062336B1 (no)
JP (1) JP4351389B2 (no)
KR (1) KR100748293B1 (no)
CN (1) CN1232641C (no)
AT (1) ATE318310T1 (no)
AU (1) AU760900B2 (no)
BG (2) BG64990B1 (no)
BR (1) BR9909659A (no)
CA (2) CA2625284A1 (no)
DE (1) DE69929958T2 (no)
DK (1) DK1062336T3 (no)
EA (1) EA004062B1 (no)
EE (1) EE200000538A (no)
ES (1) ES2258838T3 (no)
HK (1) HK1034995A1 (no)
HU (1) HUP0101612A3 (no)
IL (1) IL126024A0 (no)
NO (1) NO327854B1 (no)
NZ (2) NZ525566A (no)
PL (1) PL200763B1 (no)
PT (1) PT1062336E (no)
SK (1) SK285804B6 (no)
WO (1) WO1999047672A1 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7189832B1 (en) * 1998-08-20 2007-03-13 The Regents Of The University Of California Gamma subunit of cytokine responsive IκB-alpha kinase complex and methods of using same
US7745579B1 (en) 1998-09-01 2010-06-29 David Wallach Inhibitor of NF-KB activation
DK2270052T3 (en) 2001-06-26 2018-07-02 Amgen Inc Antibodies to OPGL
US7521534B1 (en) * 2003-03-03 2009-04-21 The University Board Of Regents Of Texas System IKK gamma gene products and methods for making and using same
BRPI0414714A (pt) * 2003-09-24 2006-11-21 Pasteur Institut polinucleotìdeo purificado, vetor, célula hospedeira, construto de fusão de polipeptìdeo, métodos de inibir a rota de sinalização de nf-capab, de interromper a oligomerização de nemo, e, de identificar polipeptìdeos que modulam a oligomerização de nemo, e, uso de uma quantidade eficaz de uma composição
EP2492281B1 (en) 2009-10-19 2018-04-11 HanAll Biopharma Co., Ltd. Modified human tumor necrosis factor receptor-1 polypeptide or fragment thereof, and method for preparing same
CN102399819B (zh) * 2011-08-24 2013-06-19 西北农林科技大学 一种质粒型腺病毒载体pAd-NRIP1及其构建方法
DE102011115480A1 (de) * 2011-10-06 2013-04-11 Biostep Gmbh Substrat und Vorrichtung zur Chemilumineszenzdetektion
SG11201704764PA (en) 2014-12-11 2017-07-28 Harvard College Inhibitors of cellular necrosis and related methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL73883A (en) * 1984-12-20 1990-12-23 Yeda Res & Dev Monoclonal antibodies against tnf-alpha,hybridomas producing them and method for the purification of tnf-alpha
IL94039A (en) * 1989-08-06 2006-09-05 Yeda Res & Dev Antibodies to tbp - 1 and their use
EP0398327B2 (en) * 1989-05-18 2013-02-20 Yeda Research And Development Co., Ltd. Tumor necrosis factor binding protein II, its purification and antibodies thereto
WO1996025941A1 (en) * 1995-02-22 1996-08-29 Yeda Research And Development Co. Ltd. Modulators of regulatory proteins
US5674734A (en) * 1995-05-18 1997-10-07 President And Fellows Of Harvard College Cell death protein
AU7457796A (en) * 1995-10-23 1997-05-15 Tularik Inc. Rip: novel human protein involved in tumor necrosis factor signal transduction, and screening assays
EP0914338A2 (en) * 1996-05-29 1999-05-12 Genzyme Corporation Cell growth regulatory genes

Also Published As

Publication number Publication date
WO1999047672A1 (en) 1999-09-23
EA200000961A1 (ru) 2001-04-23
PT1062336E (pt) 2006-05-31
HUP0101612A2 (hu) 2004-01-28
IL126024A0 (en) 1999-05-09
DE69929958T2 (de) 2006-11-23
BG109537A (en) 2007-11-30
JP2002506644A (ja) 2002-03-05
BG104769A (en) 2001-04-30
JP4351389B2 (ja) 2009-10-28
CA2323637A1 (en) 1999-09-23
AU760900B2 (en) 2003-05-22
ES2258838T3 (es) 2006-09-01
EP1062336A1 (en) 2000-12-27
PL200763B1 (pl) 2009-02-27
CN1232641C (zh) 2005-12-21
HK1034995A1 (en) 2001-11-09
PL343262A1 (en) 2001-07-30
HUP0101612A3 (en) 2005-03-29
NZ506776A (en) 2003-08-29
KR20050107527A (ko) 2005-11-11
DE69929958D1 (de) 2006-04-27
ATE318310T1 (de) 2006-03-15
EE200000538A (et) 2002-04-15
SK285804B6 (sk) 2007-08-02
BG64990B1 (bg) 2006-11-30
KR100748293B1 (ko) 2007-08-09
AU2954599A (en) 1999-10-11
NZ525566A (en) 2004-12-24
SK13762000A3 (sk) 2001-03-12
CA2625284A1 (en) 1999-09-23
EP1062336B1 (en) 2006-02-22
CN1295614A (zh) 2001-05-16
US6734174B1 (en) 2004-05-11
BG65684B1 (bg) 2009-06-30
DK1062336T3 (da) 2006-05-29
NO327854B1 (no) 2009-10-05
EA004062B1 (ru) 2003-12-25
BR9909659A (pt) 2000-11-21
NO20004649L (no) 2000-10-30

Similar Documents

Publication Publication Date Title
ATE193553T1 (de) Domänen von extrazellulären bereichen von menschlichen blutplättchen abstammenden wachstumsfaktor rezeptor-polypeptiden
TR199902426T2 (xx) Bitki b�ceklerinin kontrol�.
NO961115L (no) Humane metabotrope glutamatreseptorsubtyper (HMR4, HMR6, HMR7) og relaterte DNA forbindelser
ATE334200T1 (de) Chimäre rezeptoren
DE69534235D1 (de) Cytokin lerk-7
WO2001049728A3 (en) HUMAN PROTEINS HAVING HYDROPHOBIC DOMAINS AND DNAs ENCODING THESE PROTEINS
NO980198L (no) Modulatorer av funksjonen til FAS-reseptorer og andre proteiner
NO20004649L (no) Modulatorer av funksjonen av reseptorer av TNF/NGF- reseptorfamilien og andre proteiner
MX9704501A (es) Moduladores de la funcion de receptores de fas/ap01.
DE69831231D1 (de) Modulatoren von intrazellulären entzündungs-, zelltod- und zellüberlebenswegen, die card- und kinase-domänen enthalten
EA199900842A1 (ru) Модуляторы функции рецепторов, принадлежащих к семейству рецепторов tnf/ngf
DK0939769T3 (da) Vertebrat-Smoothened-proteiner
SG148025A1 (en) Modulators of the function of receptors of the tnf/ngf receptor family and other proteins
PT1127133E (pt) Polipeptido que proporciona permeabilidade celular
ATE329035T1 (de) Cytoplasmische tyrosin kinase
UA72877C2 (en) Modulators of metabolic ways of intracellular inflammation, cells death and survival

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees