NO164656C - Analogifremgangsmaate for fremstilling av terapeutisk aktivt 1-(4-amionfenyl)-4-methyl-7,8-methylendioxy-3,4-dihydro-5h-2,3-benzodiazepin. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktivt 1-(4-amionfenyl)-4-methyl-7,8-methylendioxy-3,4-dihydro-5h-2,3-benzodiazepin.

Info

Publication number: NO164656C
Authority: NO; Norway
Prior art keywords: amionphenyl; methylendioxy; benzodiazepine; dihydro; methyl
Prior art date: 1986-08-15

Application number

NO873426A

Other languages

English (en)

Other versions

NO164656B (no

NO873426L (no

NO873426D0 (no

Inventor

Jeno Koroesi

Tibor Lang

Ferenc Andrasi

Pal Berzsenyi

Peter Botka

Tamas Hamori

Katalin Goldschmidt

Jozsef Borsy

Istvan Elekes

Zsuzsa Lang

Original Assignee

Biogal Gyogyszergyar

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-08-15

Filing date

1987-08-14

Publication date

1990-10-31

1987-08-14 Application filed by Biogal Gyogyszergyar filed Critical Biogal Gyogyszergyar

1987-08-14 Publication of NO873426D0 publication Critical patent/NO873426D0/no

1988-02-16 Publication of NO873426L publication Critical patent/NO873426L/no

1990-07-23 Publication of NO164656B publication Critical patent/NO164656B/no

1990-10-31 Publication of NO164656C publication Critical patent/NO164656C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Psychiatry (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

NO873426A 1986-08-15 1987-08-14 Analogifremgangsmaate for fremstilling av terapeutisk aktivt 1-(4-amionfenyl)-4-methyl-7,8-methylendioxy-3,4-dihydro-5h-2,3-benzodiazepin. NO164656C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU863594A HU198494B (en)	1986-08-15	1986-08-15	Process for producing new 3,4-dihydro-5h-2,3-benzodiazepine derivative and acid addition salts thereof, as well as pharmaceutical compositions comprising same

Publications (4)

Publication Number	Publication Date
NO873426D0 NO873426D0 (no)	1987-08-14
NO873426L NO873426L (no)	1988-02-16
NO164656B NO164656B (no)	1990-07-23
NO164656C true NO164656C (no)	1990-10-31

Family

ID=10964707

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO873426A NO164656C (no)	1986-08-15	1987-08-14	Analogifremgangsmaate for fremstilling av terapeutisk aktivt 1-(4-amionfenyl)-4-methyl-7,8-methylendioxy-3,4-dihydro-5h-2,3-benzodiazepin.

Country Status (23)

Country	Link
US (1)	US4835152A (no)
JP (1)	JPS6399073A (no)
AT (1)	ATA202187A (no)
AU (1)	AU596206B2 (no)
BE (1)	BE1002415A4 (no)
CA (1)	CA1284322C (no)
CH (1)	CH673652A5 (no)
CS (1)	CS264150B2 (no)
DD (1)	DD265627A5 (no)
DE (1)	DE3727226A1 (no)
DK (1)	DK164555C (no)
ES (1)	ES2004985A6 (no)
FI (1)	FI85706C (no)
FR (1)	FR2602773B1 (no)
GB (1)	GB2194236B (no)
HU (1)	HU198494B (no)
IT (1)	IT1222508B (no)
NL (1)	NL8701909A (no)
NO (1)	NO164656C (no)
PL (1)	PL148535B1 (no)
RU (1)	RU1779251C (no)
SE (1)	SE467357B (no)
YU (1)	YU46223B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5639751A (en) *	1990-12-21	1997-06-17	Cyogyszerkutato Intezet Kft	N-acyl-2,3-benzodiazepine derivatives for treating acute and chronic neurodegenerative disorders
HU219778B (hu) *	1990-12-21	2001-07-30	Gyógyszerkutató Intézet Közös Vállalat	Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények
HU206719B (en) *	1990-12-21	1992-12-28	Gyogyszerkutato Intezet	Process for producing 1-/4-acylamino-phenyl/-7,8-methylenedioxy-5h-2,3-benzodiazepine derivatives, acid addicional salts and pharmaceutical compositions containing them
US6288057B1 (en) *	1994-08-31	2001-09-11	Eli Lilly And Company	Physical form of dihydro-2,3-benzodiazepine derivative
TR199501071A2 (tr)	1994-08-31	1996-06-21	Lilly Co Eli	Dihidro-2,3-benzodiazepin türevlerinin üretilmesi icin stereoselektif islem.
US5891871A (en) *	1996-03-21	1999-04-06	Cocensys, Inc.	Substituted 2,3-benzodiazepin-4-ones and the use thereof
UA67749C2 (uk) *	1997-08-12	2004-07-15	Егіш Дьйодьсердьяр Рт.	Похідна 8-заміщеного-9н-1,3-діоксол/4,5-h//2,3/бензодіазепіну з властивостями амра/каїнатного антагоніста, спосіб одержання похідних, фармацевтична композиція (варіанти), спосіб її одержання та спосіб лікування
US6649607B2 (en) *	2001-05-18	2003-11-18	Vela Pharmaceuticals, Inc.	Compositions and methods for treating or preventing convulsions or seizures
JP2006510634A (ja) *	2002-12-03	2006-03-30	ヴェラファーマスーティカルズインコーポレイテッド	１−（３，４−ジメトキシフェニル）−４−メチル−５−エチル−７−メトキシ−８−ヒドロキシ−５ｈ−２，３−ベンゾジアゼピンの製薬組成物及びその用途
US6638928B1 (en)	2002-12-03	2003-10-28	Vela Pharmaceuticals, Inc.	Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
EP1575521A4 (en) *	2002-12-03	2008-04-30	Vela Acquisition Corp	PHARMACEUTICAL COMPOSITION OF 1- (3-HYDROXY-4-METHOXYPHENYL) -4-METHYL-5-ETHYL-7,8-DIMETHOXY-5H-2,3-BENZODIAZEPINE AND ITS USE
US7022700B2 (en) *	2002-12-03	2006-04-04	Vela Pharmaceuticals, Inc.	Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
US6864251B2 (en) *	2002-12-03	2005-03-08	Vela Pharmaceuticals, Inc.	Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
US20040224943A1 (en) *	2003-02-19	2004-11-11	Leventer Steven M.	Method of lowering body temperature with (R) - 2,3-benzodiazepines
US20040162284A1 (en) *	2003-02-19	2004-08-19	Harris Herbert W.	Method of lowering body temperature with (S) tofisopam
US20070021412A1 (en) *	2003-05-16	2007-01-25	Vela Pharmaceuticals, Inc.	Treatment of gastrointestinal dysfunction and related stress with an enantiomerically-pure (S) 2,3-benzodiazepine
EP1624875A4 (en) *	2003-05-16	2010-01-20	Vela Acquisition Corp	TREATMENT OF GASTROINTESTINAL DYSFUNCTION AND RELATED LOADS WITH ENANTIOMERIC PURE (R) 2,3-BENZODIAZEPINE
US20040254173A1 (en) *	2003-06-13	2004-12-16	Leventer Steven M.	Modulation of dopamine responses with substituted (S)-2,3-benzodiazepines
US20050096464A1 (en) *	2003-10-30	2005-05-05	Heikki Heikkila	Separation process
EP4197536A1 (en) *	2021-12-20	2023-06-21	Universitat de València	Haloperidol for use in the treatment of spinal muscular atrophy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU186760B (en) *	1981-03-12	1985-09-30	Gyogyszerkutato Intezet	Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives
DE3319491A1 (de) *	1982-06-19	1983-10-13	Alps Electric Co., Ltd., Tokyo	Papierfuehrungsmechanismus fuer schreibgeraete
HU191698B (en) *	1984-07-27	1987-03-30	Gyogyszerkutato Intezet	Process for producing new 1-aryl-5h-2beta-benzodiazepines

1986
- 1986-08-15 HU HU863594A patent/HU198494B/hu not_active IP Right Cessation
1987
- 1987-08-11 AT AT0202187A patent/ATA202187A/de not_active Application Discontinuation
- 1987-08-12 CH CH3115/87A patent/CH673652A5/de not_active IP Right Cessation
- 1987-08-13 YU YU151487A patent/YU46223B/sh unknown
- 1987-08-14 SE SE8703169A patent/SE467357B/sv not_active IP Right Cessation
- 1987-08-14 NO NO873426A patent/NO164656C/no unknown
- 1987-08-14 AU AU76880/87A patent/AU596206B2/en not_active Ceased
- 1987-08-14 DD DD87306060A patent/DD265627A5/de not_active IP Right Cessation
- 1987-08-14 DE DE19873727226 patent/DE3727226A1/de not_active Withdrawn
- 1987-08-14 DK DK424887A patent/DK164555C/da not_active IP Right Cessation
- 1987-08-14 BE BE8700909A patent/BE1002415A4/fr not_active IP Right Cessation
- 1987-08-14 FR FR878711578A patent/FR2602773B1/fr not_active Expired - Lifetime
- 1987-08-14 NL NL8701909A patent/NL8701909A/nl not_active Application Discontinuation
- 1987-08-14 GB GB8719265A patent/GB2194236B/en not_active Expired - Lifetime
- 1987-08-14 PL PL1987267326A patent/PL148535B1/pl unknown
- 1987-08-14 JP JP62201967A patent/JPS6399073A/ja active Pending
- 1987-08-14 RU SU874203196A patent/RU1779251C/ru active
- 1987-08-14 CS CS876007A patent/CS264150B2/cs unknown
- 1987-08-14 CA CA000544626A patent/CA1284322C/en not_active Expired - Lifetime
- 1987-08-14 IT IT21667/87A patent/IT1222508B/it active
- 1987-08-14 FI FI873525A patent/FI85706C/fi not_active IP Right Cessation
- 1987-08-14 ES ES8702415A patent/ES2004985A6/es not_active Expired
- 1987-08-20 US US07/087,341 patent/US4835152A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
NO164656B (no)	1990-07-23
FI873525A0 (fi)	1987-08-14
GB2194236A (en)	1988-03-02
FI873525A (fi)	1988-02-16
AU7688087A (en)	1988-02-18
GB8719265D0 (en)	1987-09-23
DK424887D0 (da)	1987-08-14
BE1002415A4 (fr)	1991-02-05
FR2602773A1 (fr)	1988-02-19
US4835152A (en)	1989-05-30
ES2004985A6 (es)	1989-02-16
DK164555B (da)	1992-07-13
CS264150B2 (en)	1989-06-13
YU46223B (sh)	1993-05-28
RU1779251C (ru)	1992-11-30
NL8701909A (nl)	1988-03-01
PL148535B1 (en)	1989-10-31
SE8703169D0 (sv)	1987-08-14
IT8721667A0 (it)	1987-08-14
DK424887A (da)	1988-02-16
DK164555C (da)	1992-11-30
HU198494B (en)	1989-10-30
GB2194236B (en)	1990-03-21
ATA202187A (de)	1993-06-15
NO873426L (no)	1988-02-16
DD265627A5 (de)	1989-03-08
FR2602773B1 (fr)	1990-11-02
SE467357B (sv)	1992-07-06
HUT47287A (en)	1989-02-28
DE3727226A1 (de)	1988-02-18
NO873426D0 (no)	1987-08-14
CA1284322C (en)	1991-05-21
FI85706C (fi)	1992-05-25
IT1222508B (it)	1990-09-05
CS600787A2 (en)	1988-08-16
FI85706B (fi)	1992-02-14
AU596206B2 (en)	1990-04-26
YU151487A (en)	1988-12-31
JPS6399073A (ja)	1988-04-30
SE8703169L (sv)	1988-02-16
CH673652A5 (no)	1990-03-30

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