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MX9802817A - Un agente para curar padecimientos oftalmologicos. - Google Patents

Un agente para curar padecimientos oftalmologicos.

Info

Publication number
MX9802817A
MX9802817A MX9802817A MX9802817A MX9802817A MX 9802817 A MX9802817 A MX 9802817A MX 9802817 A MX9802817 A MX 9802817A MX 9802817 A MX9802817 A MX 9802817A MX 9802817 A MX9802817 A MX 9802817A
Authority
MX
Mexico
Prior art keywords
curing
carbostyril derivative
ophthalmological diseases
curing ophthalmological
agent
Prior art date
Application number
MX9802817A
Other languages
English (en)
Inventor
Hiroki Urashima
Yasuhiro Takeji
Hisashi Shinohara
Shigeki Fujisawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of MX9802817A publication Critical patent/MX9802817A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invencion proporciona un agente para curar padecimientos oftalmologicos los cuales contienen, como el ingrediente activo, un derivado carboestirilo o una sal del mismo representada por la formula general (I) (en donde R es unátomo de halogeno) particularmente la invencion proporciona un agente efectivo para curar el síndrome de xeroftalmina (ojo seco).
MX9802817A 1995-10-12 1998-04-08 Un agente para curar padecimientos oftalmologicos. MX9802817A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26389695 1995-10-12
JP5733796 1996-03-14

Publications (1)

Publication Number Publication Date
MX9802817A true MX9802817A (es) 1998-09-30

Family

ID=26398366

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9802817A MX9802817A (es) 1995-10-12 1998-04-08 Un agente para curar padecimientos oftalmologicos.

Country Status (16)

Country Link
US (1) US6060486A (es)
EP (1) EP0859615B1 (es)
KR (1) KR100281865B1 (es)
CN (1) CN1132580C (es)
AR (3) AR004214A1 (es)
AT (1) ATE201992T1 (es)
AU (1) AU709734B2 (es)
CA (1) CA2234247C (es)
DE (1) DE69613386T2 (es)
DK (1) DK0859615T3 (es)
ES (1) ES2159043T3 (es)
GR (1) GR3036457T3 (es)
MX (1) MX9802817A (es)
PT (1) PT859615E (es)
TW (1) TW446702B (es)
WO (1) WO1997013515A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506412B2 (en) 2000-11-29 2003-01-14 Sciencebased Health Treatment of dry eye syndrome
US6623754B2 (en) * 2001-05-21 2003-09-23 Noveon Ip Holdings Corp. Dosage form of N-acetyl cysteine
DE10133870A1 (de) * 2001-07-12 2003-02-06 Chris P Lohmann Ophthalmisches Mittel, Verwendung von EGF zur Behandlung von Dry Eye-Syndrom und Insert zur Verabreichung von EGF am Auge
KR100907407B1 (ko) * 2002-09-28 2009-07-10 주식회사 케이티 대량 메시지 동보 전송을 위한 메시지 예약 및 전송 방법
KR100681360B1 (ko) * 2003-07-30 2007-02-12 오츠카 세이야쿠 가부시키가이샤 타액분비 촉진용 카르보스티릴 유도체
ES2381672T3 (es) * 2003-11-14 2012-05-30 Senju Pharmaceutical Co., Ltd. Preparación en solución acuosa que comprende un antibiótico aminoglicósido y bromfenaco
TWI340650B (en) 2004-01-21 2011-04-21 Otsuka Pharma Co Ltd Amine saly of carbostyril derivative
JPWO2006022291A1 (ja) 2004-08-27 2008-05-08 千寿製薬株式会社 ドライアイ治療用点眼液
TWI363626B (en) * 2004-11-15 2012-05-11 Otsuka Pharma Co Ltd Aqueous ophthalmic suspension of crystalline rebamipide
TW200808375A (en) * 2006-05-12 2008-02-16 Otsuka Pharma Co Ltd Hydrogel suspension and manufacturing process thereof
TWI415629B (zh) * 2006-10-26 2013-11-21 Otsuka Pharma Co Ltd 含有瑞巴匹特之水性醫藥懸浮物及其製造方法
AU2009261101B2 (en) * 2008-06-19 2013-11-07 Otsuka Pharmaceutical Co., Ltd. A pharmaceutical composition comprising rebamipide
US9248196B2 (en) 2011-02-25 2016-02-02 Nuformix Limited Rebamipide complexes and cocrystals
TW201322982A (zh) 2011-11-01 2013-06-16 Otsuka Pharma Co Ltd 用於治療前眼疾病之藥劑，該藥劑包含瑞巴派特及眼淚保持劑
KR101692578B1 (ko) * 2013-04-18 2017-01-03 삼진제약주식회사 레바미피드 또는 이의 전구체를 포함하는 안구건조증의 예방 또는 치료를 위한 경구용 약제학적 조성물
EP3954269A1 (en) * 2014-05-02 2022-02-16 Massachusetts Eye & Ear Infirmary Grading corneal fluorescein staining
KR20170039347A (ko) 2015-10-01 2017-04-11 삼진제약주식회사 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법
KR102307958B1 (ko) 2015-10-01 2021-10-05 삼진제약주식회사 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법
BR112019018367A2 (pt) * 2017-03-05 2020-04-07 Resdevco Res And Development Co Ltd uso de uma preparação oftálmica para tratamento de irritação não decorrente de infecção
KR102615076B1 (ko) 2021-07-14 2023-12-19 대우제약 주식회사 안정한 레바미피드 점안제의 대용량 제조 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI80022C (fi) * 1982-07-05 1990-04-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av ett nytt, terapeutiskt anvaendbart karbostyrilderivat.
JPH0713138B2 (ja) * 1986-07-30 1995-02-15 保土谷化学工業株式会社 ポリテトラメチレンエ−テルグリコ−ルの製法
EP0543018B1 (en) * 1991-06-07 1996-01-10 Otsuka Pharmaceutical Co., Ltd. Antidiabetic agent
TW227558B (es) * 1992-05-14 1994-08-01 Otsuka Pharma Co Ltd
CN1105799A (zh) * 1993-03-18 1995-07-26 大制药株式会社 作为基质金属蛋白酶抑制剂的喹诺酮衍生物
JP2839847B2 (ja) * 1993-10-21 1998-12-16 大塚製薬株式会社 インターロイキン−８産生抑制剤
KR970704439A (ko) * 1994-08-10 1997-09-06 오쓰카 아키히코 눈의 염증 및/또는 상처의 예방 및 치료 방법(Method of preventing and treating ophthalmic inflammation and/or wound)

Also Published As

Publication number Publication date
DE69613386D1 (de) 2001-07-19
DE69613386T2 (de) 2002-05-23
KR100281865B1 (ko) 2001-02-15
ES2159043T3 (es) 2001-09-16
ATE201992T1 (de) 2001-06-15
CA2234247A1 (en) 1997-04-17
AU7097596A (en) 1997-04-30
EP0859615B1 (en) 2001-06-13
AR070051A2 (es) 2010-03-10
US6060486A (en) 2000-05-09
CN1202108A (zh) 1998-12-16
PT859615E (pt) 2001-09-28
CA2234247C (en) 2005-05-10
GR3036457T3 (en) 2001-11-30
WO1997013515A1 (en) 1997-04-17
KR19990064187A (ko) 1999-07-26
EP0859615A1 (en) 1998-08-26
AR004214A1 (es) 1998-11-04
TW446702B (en) 2001-07-21
DK0859615T3 (da) 2001-09-03
AR055393A2 (es) 2007-08-22
AU709734B2 (en) 1999-09-02
CN1132580C (zh) 2003-12-31

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