AR055393A2 - Uso de un derivado de carboestirilo para la preparcion de una composicion farmaceutica para tratar enfermedades oftalmologicas - Google Patents
Uso de un derivado de carboestirilo para la preparcion de una composicion farmaceutica para tratar enfermedades oftalmologicasInfo
- Publication number
- AR055393A2 AR055393A2 ARP060103704A ARP060103704A AR055393A2 AR 055393 A2 AR055393 A2 AR 055393A2 AR P060103704 A ARP060103704 A AR P060103704A AR P060103704 A ARP060103704 A AR P060103704A AR 055393 A2 AR055393 A2 AR 055393A2
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- pharmaceutical composition
- derivative
- carboestirile
- ophthalmological diseases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Uso de un derivado de carboestirilo o una sal del mismo, que tiene la formula (1), (donde R es un átomo de halogeno, la posicion substituida de la cadena lateral de la formula (2), es la posicion 3- o 4- en la estructura de carboestirilo, y el enlace carbono-carbono entre las posiciones 3- y 4- en la estructura de carboestirilo es un enlace simple o un enlace doble) para la preparacion de una composicion farmacéutica para curar enfermedades oftálmicas seleccionadas de síndrome de xeroftalmia (ojo seco) y lesiones de los ojos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP26389695 | 1995-10-12 | ||
| JP5733796 | 1996-03-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR055393A2 true AR055393A2 (es) | 2007-08-22 |
Family
ID=26398366
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP960104658A AR004214A1 (es) | 1995-10-12 | 1996-09-10 | Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas |
| ARP060103704A AR055393A2 (es) | 1995-10-12 | 2006-08-25 | Uso de un derivado de carboestirilo para la preparcion de una composicion farmaceutica para tratar enfermedades oftalmologicas |
| ARP080105747A AR070051A2 (es) | 1995-10-12 | 2008-12-29 | Una preparacion farmaceutica para la cura del sindrome de xeroftalmia |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP960104658A AR004214A1 (es) | 1995-10-12 | 1996-09-10 | Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080105747A AR070051A2 (es) | 1995-10-12 | 2008-12-29 | Una preparacion farmaceutica para la cura del sindrome de xeroftalmia |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6060486A (es) |
| EP (1) | EP0859615B1 (es) |
| KR (1) | KR100281865B1 (es) |
| CN (1) | CN1132580C (es) |
| AR (3) | AR004214A1 (es) |
| AT (1) | ATE201992T1 (es) |
| AU (1) | AU709734B2 (es) |
| CA (1) | CA2234247C (es) |
| DE (1) | DE69613386T2 (es) |
| DK (1) | DK0859615T3 (es) |
| ES (1) | ES2159043T3 (es) |
| GR (1) | GR3036457T3 (es) |
| MX (1) | MX9802817A (es) |
| PT (1) | PT859615E (es) |
| TW (1) | TW446702B (es) |
| WO (1) | WO1997013515A1 (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6506412B2 (en) | 2000-11-29 | 2003-01-14 | Sciencebased Health | Treatment of dry eye syndrome |
| US6623754B2 (en) * | 2001-05-21 | 2003-09-23 | Noveon Ip Holdings Corp. | Dosage form of N-acetyl cysteine |
| DE10133870A1 (de) * | 2001-07-12 | 2003-02-06 | Chris P Lohmann | Ophthalmisches Mittel, Verwendung von EGF zur Behandlung von Dry Eye-Syndrom und Insert zur Verabreichung von EGF am Auge |
| KR100907407B1 (ko) * | 2002-09-28 | 2009-07-10 | 주식회사 케이티 | 대량 메시지 동보 전송을 위한 메시지 예약 및 전송 방법 |
| KR100681360B1 (ko) * | 2003-07-30 | 2007-02-12 | 오츠카 세이야쿠 가부시키가이샤 | 타액분비 촉진용 카르보스티릴 유도체 |
| ES2381672T3 (es) * | 2003-11-14 | 2012-05-30 | Senju Pharmaceutical Co., Ltd. | Preparación en solución acuosa que comprende un antibiótico aminoglicósido y bromfenaco |
| TWI340650B (en) | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
| JPWO2006022291A1 (ja) | 2004-08-27 | 2008-05-08 | 千寿製薬株式会社 | ドライアイ治療用点眼液 |
| TWI363626B (en) * | 2004-11-15 | 2012-05-11 | Otsuka Pharma Co Ltd | Aqueous ophthalmic suspension of crystalline rebamipide |
| TW200808375A (en) * | 2006-05-12 | 2008-02-16 | Otsuka Pharma Co Ltd | Hydrogel suspension and manufacturing process thereof |
| TWI415629B (zh) * | 2006-10-26 | 2013-11-21 | Otsuka Pharma Co Ltd | 含有瑞巴匹特之水性醫藥懸浮物及其製造方法 |
| AU2009261101B2 (en) * | 2008-06-19 | 2013-11-07 | Otsuka Pharmaceutical Co., Ltd. | A pharmaceutical composition comprising rebamipide |
| US9248196B2 (en) | 2011-02-25 | 2016-02-02 | Nuformix Limited | Rebamipide complexes and cocrystals |
| TW201322982A (zh) | 2011-11-01 | 2013-06-16 | Otsuka Pharma Co Ltd | 用於治療前眼疾病之藥劑，該藥劑包含瑞巴派特及眼淚保持劑 |
| KR101692578B1 (ko) * | 2013-04-18 | 2017-01-03 | 삼진제약주식회사 | 레바미피드 또는 이의 전구체를 포함하는 안구건조증의 예방 또는 치료를 위한 경구용 약제학적 조성물 |
| EP3954269A1 (en) * | 2014-05-02 | 2022-02-16 | Massachusetts Eye & Ear Infirmary | Grading corneal fluorescein staining |
| KR20170039347A (ko) | 2015-10-01 | 2017-04-11 | 삼진제약주식회사 | 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법 |
| KR102307958B1 (ko) | 2015-10-01 | 2021-10-05 | 삼진제약주식회사 | 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법 |
| BR112019018367A2 (pt) * | 2017-03-05 | 2020-04-07 | Resdevco Res And Development Co Ltd | uso de uma preparação oftálmica para tratamento de irritação não decorrente de infecção |
| KR102615076B1 (ko) | 2021-07-14 | 2023-12-19 | 대우제약 주식회사 | 안정한 레바미피드 점안제의 대용량 제조 방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI80022C (fi) * | 1982-07-05 | 1990-04-10 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av ett nytt, terapeutiskt anvaendbart karbostyrilderivat. |
| JPH0713138B2 (ja) * | 1986-07-30 | 1995-02-15 | 保土谷化学工業株式会社 | ポリテトラメチレンエ−テルグリコ−ルの製法 |
| EP0543018B1 (en) * | 1991-06-07 | 1996-01-10 | Otsuka Pharmaceutical Co., Ltd. | Antidiabetic agent |
| TW227558B (es) * | 1992-05-14 | 1994-08-01 | Otsuka Pharma Co Ltd | |
| CN1105799A (zh) * | 1993-03-18 | 1995-07-26 | 大制药株式会社 | 作为基质金属蛋白酶抑制剂的喹诺酮衍生物 |
| JP2839847B2 (ja) * | 1993-10-21 | 1998-12-16 | 大塚製薬株式会社 | インターロイキン−８産生抑制剤 |
| KR970704439A (ko) * | 1994-08-10 | 1997-09-06 | 오쓰카 아키히코 | 눈의 염증 및/또는 상처의 예방 및 치료 방법(Method of preventing and treating ophthalmic inflammation and/or wound) |
-
1996
- 1996-09-10 AR ARP960104658A patent/AR004214A1/es not_active Application Discontinuation
- 1996-10-01 EP EP96932058A patent/EP0859615B1/en not_active Expired - Lifetime
- 1996-10-01 AT AT96932058T patent/ATE201992T1/de active
- 1996-10-01 AU AU70975/96A patent/AU709734B2/en not_active Expired
- 1996-10-01 PT PT96932058T patent/PT859615E/pt unknown
- 1996-10-01 KR KR1019980702671A patent/KR100281865B1/ko not_active IP Right Cessation
- 1996-10-01 WO PCT/JP1996/002850 patent/WO1997013515A1/en active IP Right Grant
- 1996-10-01 US US09/051,194 patent/US6060486A/en not_active Expired - Lifetime
- 1996-10-01 CN CN96198194A patent/CN1132580C/zh not_active Expired - Lifetime
- 1996-10-01 DE DE69613386T patent/DE69613386T2/de not_active Expired - Lifetime
- 1996-10-01 CA CA002234247A patent/CA2234247C/en not_active Expired - Lifetime
- 1996-10-01 DK DK96932058T patent/DK0859615T3/da active
- 1996-10-01 ES ES96932058T patent/ES2159043T3/es not_active Expired - Lifetime
- 1996-10-02 TW TW085112022A patent/TW446702B/zh not_active IP Right Cessation
-
1998
- 1998-04-08 MX MX9802817A patent/MX9802817A/es unknown
-
2001
- 2001-08-27 GR GR20010401307T patent/GR3036457T3/el unknown
-
2006
- 2006-08-25 AR ARP060103704A patent/AR055393A2/es not_active Application Discontinuation
-
2008
- 2008-12-29 AR ARP080105747A patent/AR070051A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69613386D1 (de) | 2001-07-19 |
| DE69613386T2 (de) | 2002-05-23 |
| KR100281865B1 (ko) | 2001-02-15 |
| ES2159043T3 (es) | 2001-09-16 |
| ATE201992T1 (de) | 2001-06-15 |
| CA2234247A1 (en) | 1997-04-17 |
| AU7097596A (en) | 1997-04-30 |
| EP0859615B1 (en) | 2001-06-13 |
| AR070051A2 (es) | 2010-03-10 |
| US6060486A (en) | 2000-05-09 |
| CN1202108A (zh) | 1998-12-16 |
| PT859615E (pt) | 2001-09-28 |
| CA2234247C (en) | 2005-05-10 |
| GR3036457T3 (en) | 2001-11-30 |
| WO1997013515A1 (en) | 1997-04-17 |
| KR19990064187A (ko) | 1999-07-26 |
| MX9802817A (es) | 1998-09-30 |
| EP0859615A1 (en) | 1998-08-26 |
| AR004214A1 (es) | 1998-11-04 |
| TW446702B (en) | 2001-07-21 |
| DK0859615T3 (da) | 2001-09-03 |
| AU709734B2 (en) | 1999-09-02 |
| CN1132580C (zh) | 2003-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR055393A2 (es) | Uso de un derivado de carboestirilo para la preparcion de una composicion farmaceutica para tratar enfermedades oftalmologicas | |
| ES2175127T3 (es) | Derivados de la quinazolina y su uso. | |
| ES2147294T3 (es) | Compuestos terapeuticos. | |
| ES2154262T3 (es) | Uso de compuestos macrolidos para enfermedades oculares. | |
| ES2186670T3 (es) | Derivados de prostaglandina para el tratamiento del glaucoma o la hipertension ocular. | |
| BR9714363A (pt) | Derivados de pirazol substituìdos para o tratamento de doenças circulatórias cardìacas | |
| ES2051641A1 (es) | Procedimientos para la preparacion de compuestos derivados de tiourea. | |
| BR9810745A (pt) | Derivados de benzimidazol | |
| ES2064130T3 (es) | Utilizacion de droloxifeno para el tratamiento de enfermedades de los huesos. | |
| ES2093735T3 (es) | Derivados de melatonina para uso en la terapia de trastornos del sueño y en medicacion preanestesica. | |
| AR004700A1 (es) | 1alfa, 26 dihidroxi-d-homo-vitamina d3, una composicion farmaceutica que la comprende, un procedimiento para su preparacion y el uso de los mismos en laelaboracion de un medicamento | |
| AR023715A1 (es) | Composicion farmaceutica para un sujeto que necesita una elevacion del contenido de nad intracelular, y el uso de la misma para la manufactura de unmedicamento para aumentar las respuestas celulares protectoras al stress genotoxico en la piel | |
| ES2160648T3 (es) | Derivados de piridina. | |
| ES2080307T3 (es) | Composiciones farmaceuticas. | |
| ES2084579T3 (es) | Uso de buspirona en la preparacion de una composicion farmaceutica para el tratamiento del abuso del alcohol. | |
| ES2156287T3 (es) | Derivados de difenilmetilen piperidina. | |
| HN2000000050A (es) | Sal mutua de amlodipino y atorvastatina | |
| ES2129485T3 (es) | Derivados de acidos guanidinoalquil-1,1-bisfosfonicos, procedimiento para su preparacion y su utilizacion. | |
| ES2045182T3 (es) | Substancias fisiologicamente activas, un proceso para la preparacion de las mismas y composiciones farmaceuticas que las contienen. | |
| AR012504A1 (es) | Utilizacion de derivados de tetrahidropiridina, para la preparacion de medicamentos para el tratamiento de las enfermedades que provocan unadesmielinizacion. | |
| AR017723A1 (es) | Uso de 4-(1-etil-propoxi)3,6-dimetil-2-(2,4,6-trimetil-fenoxi)piridina o (3,6-dimetil-2-(2,4,6-trimetil-fenoxi)-piridin-4-il)-(1-etil-propil)-amina, unprofarmaco de las mismas o una sal farmaceuticamente aceptable de las mismas o de dicho profarmaco para la preparacion de un medicamento para el trat | |
| MX9202152A (es) | Derivados del indol, procedimiento para su preparacion y composicion farmaceutica que los contiene. | |
| ES2038650T3 (es) | Procedimiento para preparar una composicion farmaceutica que comprende 3'-desoxitimidin-2'-eno-(3'-desoxi-2',3'-dideshidrotimidina) para tratar pacientes infectados con retrovirus. | |
| ES2123499T3 (es) | Metodos y composiciones para tratamiento de infecciones virales. | |
| BG101605A (bg) | Ентерокинетични бензамиди |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |