LT2500017T - Ketogeninių junginių panaudojimas senatvinio atminties susilpnėjimo gydymui - Google Patents
Ketogeninių junginių panaudojimas senatvinio atminties susilpnėjimo gydymuiInfo
- Publication number
- LT2500017T LT2500017T LTEP12160599.2T LT12160599T LT2500017T LT 2500017 T LT2500017 T LT 2500017T LT 12160599 T LT12160599 T LT 12160599T LT 2500017 T LT2500017 T LT 2500017T
- Authority
- LT
- Lithuania
- Prior art keywords
- age
- treatment
- associated memory
- memory impairment
- ketogenic compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 230000002361 ketogenic effect Effects 0.000 title 1
- 206010027175 memory impairment Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Physiology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74414006P | 2006-04-03 | 2006-04-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
LT2500017T true LT2500017T (lt) | 2017-12-11 |
Family
ID=38564302
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP07797196.8T LT2001293T (lt) | 2006-04-03 | 2007-04-03 | Ketogeninių junginių panaudojimas su amžiumi susijusių atminties pažeidimų gydymui |
LTEP12160599.2T LT2500017T (lt) | 2006-04-03 | 2007-04-03 | Ketogeninių junginių panaudojimas senatvinio atminties susilpnėjimo gydymui |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP07797196.8T LT2001293T (lt) | 2006-04-03 | 2007-04-03 | Ketogeninių junginių panaudojimas su amžiumi susijusių atminties pažeidimų gydymui |
Country Status (11)
Country | Link |
---|---|
US (3) | US8124589B2 (lt) |
EP (2) | EP2001293B9 (lt) |
JP (4) | JP2009532496A (lt) |
KR (2) | KR20090003148A (lt) |
DK (2) | DK2500017T3 (lt) |
ES (2) | ES2697504T3 (lt) |
HU (2) | HUE035852T2 (lt) |
LT (2) | LT2001293T (lt) |
PT (2) | PT2001293T (lt) |
SI (1) | SI2001293T1 (lt) |
WO (1) | WO2007115282A2 (lt) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6323237B1 (en) * | 1997-03-17 | 2001-11-27 | Btg International Limited | Therapeutic compositions |
US20020006959A1 (en) * | 2000-05-01 | 2002-01-17 | Henderson Samuel T. | Use of medium chain triglycerides for the treatment and prevention of Alzheimer's Disease and other diseases resulting from reduced Neuronal Metabolism |
US20080009467A1 (en) * | 2000-05-01 | 2008-01-10 | Accera, Inc. | Combinations of medium chain triglycerides and therapeutic agents for the treatment and prevention of alzheimers disease and other diseases resulting from reduced neuronal metabolism |
US6835750B1 (en) | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
US20070179197A1 (en) * | 2000-05-01 | 2007-08-02 | Accera, Inc. | Compositions and methods for improving or preserving brain function |
US20060280721A1 (en) | 2003-06-03 | 2006-12-14 | The Gov Of Usa Represented By Secretary Of Dpt Of | Nutritional supplements and therapeutic compositions comprising (r)-3- hydroxybutyrate derivatives |
US20060252775A1 (en) * | 2005-05-03 | 2006-11-09 | Henderson Samuel T | Methods for reducing levels of disease associated proteins |
US20070135376A1 (en) * | 2005-06-20 | 2007-06-14 | Accera, Inc. | Method to reduce oxidative damage and improve mitochondrial efficiency |
RU2437656C2 (ru) * | 2005-12-15 | 2011-12-27 | Нестек С.А. | Композиции и способы для сохранения функции головного мозга |
PT2001293T (pt) | 2006-04-03 | 2018-11-28 | Accera Inc | Utilização de compostos cetogénicos para tratamento de comprometimento da memória associado à idade |
EP1929995A1 (en) | 2006-12-04 | 2008-06-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anaplerotic therapy of Huntington disease and other polyglutamine diseases |
CN101795701A (zh) * | 2007-05-14 | 2010-08-04 | 纽尔雅制药公司 | 用于治疗神经元代谢减退的乙酰coa羧化酶抑制剂 |
EP2650380B1 (en) | 2007-07-31 | 2015-09-16 | Accera, Inc. | Use of genomic testing and ketogenic compounds for treatment of reduced cognitive function |
US20100233304A1 (en) * | 2008-01-04 | 2010-09-16 | Yuanlong Pan | Compositions comprising unsaturated fatty acids and nitric oxide releasing compounds and use thereof for enhancing cognitive and related functions |
TR201908522T4 (tr) | 2008-01-04 | 2019-07-22 | The Government Of The U S A As Represented By The Secretary Dept Of Health And Human Services | Kan lipidi düşürücü maddeler olarak keton gövdeleri ve keton gövde esterleri. |
AU2009266869B2 (en) | 2008-07-03 | 2016-07-07 | Cerecin Inc. | Monoglyceride of acetoacetate and derivatives for the treatment of neurological disorders |
US8105809B2 (en) * | 2008-07-03 | 2012-01-31 | Accera, Inc. | Enzymatic synthesis of acetoacetate esters and derivatives |
KR20110049801A (ko) * | 2008-07-18 | 2011-05-12 | 다트 뉴로사이언시즈, 엘엘씨 | 기억 물질의 평가를 위한 방법 및 시스템 |
US8642654B2 (en) | 2009-04-16 | 2014-02-04 | Isis Innovation Limited | Hydroxybutyrate ester and medical use thereof |
MY150593A (en) | 2008-11-06 | 2014-01-30 | Nisshin Oillio Group Ltd | Concentrated liquid diet |
US20110201558A1 (en) * | 2009-12-30 | 2011-08-18 | Baylor Research Institute | Anaplerotic Therapy for Alzheimer's Disease and the Aging Brain |
GB201002983D0 (en) * | 2010-02-22 | 2010-04-07 | Tdeltas Ltd | Nutritinal composition |
JP2013521827A (ja) * | 2010-03-24 | 2013-06-13 | ネステク ソシエテ アノニム | 食用組成物の嗜好性を高めるための方法 |
AU2013337308B2 (en) | 2012-11-05 | 2018-06-21 | Tdeltas | Ketone bodies to protect tissues from damage by ionizing radiation |
US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
US9468229B2 (en) | 2012-12-13 | 2016-10-18 | National Institute Of Health And Medical Research | Triheptanoin for the treatment of glucose transport 1 deficiency |
US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
GB201304467D0 (en) | 2013-03-12 | 2013-04-24 | Tdeltas Ltd | Compound for use in protecting skin |
DK2984066T3 (en) | 2013-03-14 | 2017-05-08 | Univ Oxford Innovation Ltd | Process for preparing (R) -hydroxybutyl (R) -3-hydroxybutyrate |
CN105050594B (zh) | 2013-03-19 | 2019-11-12 | 南佛罗里达大学 | 用于产生升高和持久的酮症的组合物和方法 |
EP3689343A1 (en) | 2013-11-14 | 2020-08-05 | The University of Queensland | Neurodegenerative disorders and methods of treatment and diagnosis thereof using anaplerotic agents |
KR101791622B1 (ko) * | 2014-07-17 | 2017-10-30 | 닛신 오일리오그룹 가부시키가이샤 | 곡분을 실질적으로 포함하지 않는 구운 과자 |
WO2016013617A1 (ja) * | 2014-07-23 | 2016-01-28 | 一般財団法人糧食研究会 | 脳機能改善剤、及び認知機能障害の予防または治療剤 |
US10668041B2 (en) | 2014-12-08 | 2020-06-02 | Societe Des Produits Nestle Sa | Compositions and methods comprising medium chain triglycerides for treatment of epilepsy |
NZ730880A (en) | 2014-12-08 | 2022-07-01 | Nestle Sa | Compositions and methods comprising medium chain triglycerides for treatment of epilepsy |
JP6446265B2 (ja) * | 2014-12-26 | 2018-12-26 | 花王株式会社 | 固形状組成物 |
US10786476B2 (en) | 2016-02-23 | 2020-09-29 | Imbria Pharmaceuticals, Inc. | Combination therapy |
US10973786B2 (en) | 2016-03-11 | 2021-04-13 | Axcess Global Sciences, Llc | R-beta-hydroxybutyrate, S-beta-hydroxybutyrate, and RS-beta-hydroxybutyrate mixed salt compositions |
US10245243B1 (en) | 2017-12-19 | 2019-04-02 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the S-enantiomer and methods of use |
US11241403B2 (en) | 2016-03-11 | 2022-02-08 | Axcess Global Sciences, Llc | Beta-hydroxybutyrate mixed salt compositions and methods of use |
US11103470B2 (en) | 2017-11-22 | 2021-08-31 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
US10292952B2 (en) | 2016-03-11 | 2019-05-21 | Axcess Global Sciences, Llc | Mixed salt compositions for maintaining or restoring electrolyte balance while producing elevated and sustained ketosis |
US10596130B2 (en) | 2017-12-19 | 2020-03-24 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the S-enantiomer and methods of use |
US10973792B2 (en) | 2019-02-13 | 2021-04-13 | Axcess Global Sciences, Llc | Racemic beta-hydroxybutyrate mixed salt-acid compositions and methods of use |
US11185518B2 (en) | 2017-12-19 | 2021-11-30 | Axcess Global Sciences, Llc | S-beta-hydroxybutyrate compounds and compositions enriched with S-enantiomer |
US10736861B2 (en) | 2016-03-11 | 2020-08-11 | Axcess Global Sciences, Llc | Mixed salt compositions for producing elevated and sustained ketosis |
US10245242B1 (en) | 2017-11-22 | 2019-04-02 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
US10596129B2 (en) | 2017-11-22 | 2020-03-24 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
US10596131B2 (en) | 2017-11-22 | 2020-03-24 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
CN109069534B (zh) * | 2016-04-15 | 2021-04-20 | 广川庆裕 | 认知功能改善剂 |
US10925843B2 (en) | 2018-04-18 | 2021-02-23 | Axcess Global Sciences, Llc | Compositions and methods for keto stacking with beta-hydroxybutyrate and acetoacetate |
US12109182B2 (en) | 2016-04-19 | 2024-10-08 | Axcess Global Sciences, Llc | Administration of R-beta-hydroxybutyrate and related compounds in humans |
US11806324B2 (en) | 2018-04-18 | 2023-11-07 | Axcess Global Sciences, Llc | Beta-hydroxybutyric acid compositions and methods for oral delivery of ketone bodies |
JP6935994B2 (ja) | 2016-08-19 | 2021-09-15 | 株式会社明治 | ケトン体生成促進用組成物 |
US10945975B2 (en) * | 2016-10-24 | 2021-03-16 | University Of South Florida | Delaying latency to seizure by combinations of ketone supplements |
US20180177753A1 (en) | 2016-12-23 | 2018-06-28 | Neuroenergy Ventures, Inc. | Glyceryl 3-hydroxybutyrates for migraine symptom management |
US9925164B1 (en) | 2017-01-12 | 2018-03-27 | Neuroenergy Ventures, Inc. | Glyceryl 3-hydroxybutyrates for traumatic brain injury |
US10376528B2 (en) | 2017-03-10 | 2019-08-13 | Tecton Group, Llc | Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor |
JP6895144B2 (ja) * | 2017-04-05 | 2021-06-30 | 北海道公立大学法人 札幌医科大学 | 診断支援システム、診断支援システムの作動方法、及びプログラム |
US10770044B2 (en) * | 2017-08-31 | 2020-09-08 | Spotify Ab | Lyrics analyzer |
US11202769B2 (en) | 2017-11-22 | 2021-12-21 | Axcess Global Sciences, Llc | Ketone body esters of s-beta-hydroxybutyrate and/or s-1,3-butanediol for modifying metabolic function |
US12090129B2 (en) | 2017-11-22 | 2024-09-17 | Axcess Global Sciences, Llc | Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use |
US11944598B2 (en) | 2017-12-19 | 2024-04-02 | Axcess Global Sciences, Llc | Compositions containing s-beta-hydroxybutyrate or non-racemic mixtures enriched with the s-enatiomer |
US11241401B2 (en) | 2020-02-06 | 2022-02-08 | Axcess Global Sciences, Llc | Enantiomerically pure r-beta-hydroxybutyrate mixed salt-acid compositions |
US10980772B2 (en) | 2018-08-27 | 2021-04-20 | Axcess Global Sciences, Llc | Compositions and methods for delivering tetrahydrocannabinol and ketone bodies |
US10512615B1 (en) | 2018-08-27 | 2019-12-24 | Axcess Global Sciences, Llc | Compositions and methods for delivering cannabidiol and ketone bodies |
US11419836B2 (en) | 2019-02-13 | 2022-08-23 | Axcess Global Sciences, Llc | Racemic and near racemic beta-hydroxybutyrate mixed salt-acid compositions |
US11129802B2 (en) | 2018-08-27 | 2021-09-28 | Axcess Global Sciences, Llc | Compositions and methods for delivering cannabidiol and ketone bodies |
BR112020022985A2 (pt) * | 2018-06-21 | 2021-02-02 | Société des Produits Nestlé S.A. | composições e métodos que usam um precursor de nicotinamida adenina dinucleotídeo (nad+) e pelo menos uma cetona ou um precursor de cetona |
CN114072137A (zh) * | 2019-02-11 | 2022-02-18 | 阿克塞斯全球科学有限责任公司 | S-β-羟基丁酸根化合物和富含S-对映体的组合物 |
EP3923925A4 (en) * | 2019-02-11 | 2022-10-19 | Axcess Global Sciences, LLC | RACEMIC BETA-HYDROXYBUTYRATE MIXED SALT-ACID COMPOSITIONS AND METHODS OF USE |
SG11202109268XA (en) * | 2019-03-04 | 2021-09-29 | Cerecin Inc | Medium chain triglyceride formulations with improved bioavailiblity and methods related thereto |
US11033553B2 (en) | 2019-06-21 | 2021-06-15 | Axcess Global Sciences, Llc | Non-vasoconstricting energy-promoting compositions containing ketone bodies |
US11969430B1 (en) | 2023-03-10 | 2024-04-30 | Axcess Global Sciences, Llc | Compositions containing paraxanthine and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance |
US12167993B2 (en) | 2019-06-21 | 2024-12-17 | Axcess Global Sciences, Llc | Non-vasoconstricting energy-promoting compositions containing ketone bodies |
US11950616B2 (en) | 2019-06-21 | 2024-04-09 | Axcess Global Sciences, Llc | Non-vasoconstricting energy-promoting compositions containing ketone bodies |
JP7458620B2 (ja) * | 2019-06-21 | 2024-04-01 | 株式会社大塚製薬工場 | 栄養組成物 |
JP7010509B2 (ja) * | 2020-01-15 | 2022-01-26 | 一般社団法人 Unical | 新規配合スポーツ飲料およびその調製のための顆粒剤 |
WO2021178547A1 (en) | 2020-03-05 | 2021-09-10 | Devon Price | COMPOSITION OF (D)-β-HYDROXYBUTYRIC ACID, (D)-β-HYDROXYVALERIC ACID, AND (D)-1,3 BUTANEDIOL AS A NUTRITIONAL SUPPLEMENT AND THERAPEUTIC AGENT |
US12186297B2 (en) | 2020-08-26 | 2025-01-07 | Axcess Global Sciences, Llc | Compositions and methods for increasing lean-to-fat mass ratio |
WO2023167989A2 (en) * | 2022-03-04 | 2023-09-07 | Guardian Biosciences, LLC | Compositions and methods to promote brain health |
EP4499147A1 (en) * | 2022-03-24 | 2025-02-05 | Cerecin Inc. | Systems, methods, and devices for predicting pharmacokinetic influences on ketogenesis following administration of tricaprilin |
Family Cites Families (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2766146A (en) | 1954-07-26 | 1956-10-09 | Reynolds Tobacco Co R | Tobacco |
US2766145A (en) | 1954-07-26 | 1956-10-09 | Reynolds Tobacco Co R | Tobacco |
US3053677A (en) | 1959-11-12 | 1962-09-11 | Eastman Kodak Co | Petroleum wax for paper coatings |
US4346107A (en) * | 1979-02-12 | 1982-08-24 | Claudio Cavazza | Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism |
FR2490631A1 (fr) | 1980-09-24 | 1982-03-26 | Roussel Uclaf | Nouvelle composition lipidique utilisable en dietetique, reanimation et therapeutique |
US4528197A (en) | 1983-01-26 | 1985-07-09 | Kabivitrum Ab | Controlled triglyceride nutrition for hypercatabolic mammals |
US4551523A (en) | 1983-04-14 | 1985-11-05 | Eastman Kodak Company | Preparation of saccharide acetoacetates |
US4847296A (en) | 1984-09-13 | 1989-07-11 | Babayan Vigen K | Triglyceride preparations for the prevention of catabolism |
US5126373A (en) | 1987-11-19 | 1992-06-30 | Henri Brunengraber | Composition for parenteral and oral nutrition |
SE8803141L (sv) | 1988-09-07 | 1990-03-08 | Kabivitrum Ab | Naeringsmedel foer maenniskor och djur |
US5650148A (en) | 1988-12-15 | 1997-07-22 | The Regents Of The University Of California | Method of grafting genetically modified cells to treat defects, disease or damage of the central nervous system |
DE3843238C1 (lt) | 1988-12-22 | 1990-02-22 | Lohmann Therapie Syst Lts | |
IT1240775B (it) | 1990-02-23 | 1993-12-17 | Sigma Tau Ind Farmaceuti | Esteri della l-carnitina e di acil-l-carnitine con l'acido beta-idrossibutirrico e composizioni farmaceutiche che li contengono per la inibizione della degenerazione neuronale, della proteolisi epatica e nel trattamento del coma. |
JP3226217B2 (ja) | 1990-04-26 | 2001-11-05 | ザ、プロクター、エンド、ギャンブル、カンパニー | ポリオール脂肪酸ポリエステルを含有したショートニング組成物 |
US5538983A (en) | 1990-05-16 | 1996-07-23 | The Rockefeller University | Method of treating amyloidosis by modulation of calcium |
US5385915A (en) | 1990-05-16 | 1995-01-31 | The Rockefeller University | Treatment of amyloidosis associated with Alzheimer disease using modulators of protein phosphorylation |
US5614560A (en) | 1991-04-04 | 1997-03-25 | Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
GB9113484D0 (en) | 1991-06-21 | 1991-08-07 | Unilever Plc | Cosmetic composition |
US5276059A (en) | 1992-07-10 | 1994-01-04 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibition of diseases associated with amyloid formation |
US5308832A (en) * | 1992-07-27 | 1994-05-03 | Abbott Laboratories | Nutritional product for persons having a neurological injury |
WO1994009155A1 (en) | 1992-10-13 | 1994-04-28 | Duke University | Methods of detecting alzheimer's disease |
JP3486778B2 (ja) | 1993-04-02 | 2004-01-13 | 三菱ウェルファーマ株式会社 | アルツハイマー病予防治療剤 |
IL110309A0 (en) * | 1993-07-15 | 1994-10-21 | Univ Kentucky Res Found | A method of protecting against neuron loss |
US5420335A (en) | 1993-09-30 | 1995-05-30 | Birkhahn; Ronald H. | Parenteral nutrients based on watersoluble glycerol bisacetoacetates |
WO1995009145A1 (en) * | 1993-09-30 | 1995-04-06 | Eastman Chemical Company | NUTRITIVE GLYCEROL ESTERS OF β-ACYLOXY BUTYRATES |
US5438042B1 (en) | 1993-10-08 | 1997-08-26 | Sandoz Nutrition Ltd | Enteral nutritional composition having amino acid profile |
JP3645580B2 (ja) | 1993-10-22 | 2005-05-11 | 株式会社フジモト・ブラザーズ | グルコースエステル誘導体を含有する脳代謝改善剤 |
US5691325A (en) * | 1994-01-14 | 1997-11-25 | Sandyk; Reuven | Method for ameliorating age-related disease conditions |
US7049078B2 (en) | 1994-04-27 | 2006-05-23 | Judés Poirier | Apolipoprotein E polymorphism and treatment of alzheimer's disease |
GB9408465D0 (en) | 1994-04-27 | 1994-06-22 | Univ Mcgill | Apolipoprotein e polymorphism & treatment of alzheimer's disease |
US5607967A (en) | 1994-10-27 | 1997-03-04 | Merck & Co., Inc. | Treatment of alzheimer's disease with 5-(tetradecyloxy)-2-furan carboxylic acid |
DE69535104T2 (de) | 1994-11-08 | 2007-02-08 | Avicena Group, Inc., Cambridge | Verwendung von kreatin oder kreatinanologen zur behandlung von huntington chorea, morbus parkinson und amyotrophen lateralsklerose |
US5854215A (en) | 1995-03-14 | 1998-12-29 | Praecis Pharmaceuticals Incorporated | Modulators of β-amyloid peptide aggregation |
US5817626A (en) | 1995-03-14 | 1998-10-06 | Praecis Pharmaceuticals Incorporated | Modulators of beta-amyloid peptide aggregation |
JPH11514333A (ja) | 1995-03-14 | 1999-12-07 | プレーシス ファーマスーティカルズ インコーポレイテッド | アミロイドの凝集の調節剤 |
US6022683A (en) | 1996-12-16 | 2000-02-08 | Nova Molecular Inc. | Methods for assessing the prognosis of a patient with a neurodegenerative disease |
JP4598203B2 (ja) | 1995-12-01 | 2010-12-15 | ビーティージー・インターナショナル・リミテッド | 脳機能改善剤 |
US5936078A (en) | 1995-12-12 | 1999-08-10 | Kyowa Hakko Kogyo Co., Ltd. | DNA and protein for the diagnosis and treatment of Alzheimer's disease |
DE19609476A1 (de) | 1996-03-11 | 1997-09-18 | Basf Ag | Stabile zur parenteralen Verabreichung geeignete Carotinoid-Emulsionen |
IT1284650B1 (it) | 1996-05-24 | 1998-05-21 | Sigma Tau Ind Farmaceuti | Farmaco a base di un derivato della carnitina per il trattamento della demenza di alzheimer in pazienti ad insorgenza precoce della patologia |
KR980008239A (ko) | 1996-07-26 | 1998-04-30 | 김충환 | 사이클로스포린-함유 약학적 조성물 |
JP2001514663A (ja) | 1997-03-12 | 2001-09-11 | エスモンド,ロバート ダブリュー. | アルツハイマー病を処置または予防するための方法 |
CN1315473C (zh) * | 1997-03-17 | 2007-05-16 | 英国技术集团国际有限公司 | 治疗组合物 |
US6323237B1 (en) * | 1997-03-17 | 2001-11-27 | Btg International Limited | Therapeutic compositions |
US6316038B1 (en) | 1997-03-17 | 2001-11-13 | Btg International Limited | Therapeutic compositions |
US6352722B1 (en) | 1997-12-23 | 2002-03-05 | Quadrant Holdings Cambridge Limited | Derivatized carbohydrates, compositions comprised thereof and methods of use thereof |
US20040058873A1 (en) | 1998-03-12 | 2004-03-25 | Esmond Robert W. | Method for treating or preventing Alzheimer's disease |
EP1065931A4 (en) | 1998-04-02 | 2006-10-11 | Avicena Group Inc | COMPOSITIONS CONTAINING CREATINE COMBINED WITH A SECOND AGENT |
EP1098655B1 (en) | 1998-07-22 | 2004-11-24 | Metabolix, Inc. | Nutritional and therapeutic uses of 3-hydroxyalkanoate oligomers |
US6395306B1 (en) | 1998-09-14 | 2002-05-28 | Pan Pacific Pharmaceuticals, Inc. | Bee venom protein and gene encoding same |
CN1273129C (zh) | 1998-09-15 | 2006-09-06 | 英国技术集团国际有限公司 | 治疗组合物(ⅱ) |
GB9908202D0 (en) | 1999-04-12 | 1999-06-02 | Unilever Plc | Cosmetic compositions |
US20020006959A1 (en) | 2000-05-01 | 2002-01-17 | Henderson Samuel T. | Use of medium chain triglycerides for the treatment and prevention of Alzheimer's Disease and other diseases resulting from reduced Neuronal Metabolism |
US6835750B1 (en) * | 2000-05-01 | 2004-12-28 | Accera, Inc. | Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II |
US20070179197A1 (en) | 2000-05-01 | 2007-08-02 | Accera, Inc. | Compositions and methods for improving or preserving brain function |
DE20012857U1 (de) | 2000-07-27 | 2000-11-09 | Sportmedizin Team Vertriebs Gmbh, Berneck | Diätetisches Lebensmittel zum Fettabbau |
US6667397B2 (en) | 2000-08-25 | 2003-12-23 | Eastman Chemical Company | Methods of preparing disaccharide and trisaccharide C6-C12 fatty acid esters with high alpha content and materials therefrom |
GB2368011A (en) | 2000-10-17 | 2002-04-24 | Unilever Plc | Fatty acid esters of maltose and uses thereof |
US20020103139A1 (en) | 2000-12-01 | 2002-08-01 | M. Weisspapir | Solid self-emulsifying controlled release drug delivery system composition for enhanced delivery of water insoluble phytosterols and other hydrophobic natural compounds for body weight and cholestrol level control |
KR100479741B1 (ko) | 2000-12-30 | 2005-03-30 | 주식회사 엘지생활건강 | 글루코오스 아실화 유도체 또는 수크로오스 아실화유도체를 함유하는 피부미백제 |
JP2004534050A (ja) | 2001-06-07 | 2004-11-11 | エーザイ株式会社 | 細胞ストレスに関連する疾病及び状態を予防及び治療する方法 |
JP2003048831A (ja) * | 2001-08-02 | 2003-02-21 | Suntory Ltd | 脳機能の低下に起因する症状あるいは疾患の予防又は改善作用を有する組成物 |
WO2003028631A2 (en) | 2001-09-21 | 2003-04-10 | Accera, Inc. | Drug targets for alzheimer's disease and other diseases associated with decreased neuronal metabolism |
WO2004021980A2 (en) | 2002-09-09 | 2004-03-18 | Mitochroma Research, Inc. | Compositions and methods for treating niddm and other conditions and disorders associated with ampk regulation |
US6884454B2 (en) * | 2002-10-21 | 2005-04-26 | Julio Lionel Pimentel | Appetite suppressing diet bar |
JP3660997B2 (ja) * | 2002-11-26 | 2005-06-15 | 独立行政法人情報通信研究機構 | 3次元電界分布測定方法および3次元電界分布測定装置 |
US20050031651A1 (en) | 2002-12-24 | 2005-02-10 | Francine Gervais | Therapeutic formulations for the treatment of beta-amyloid related diseases |
EP1605950A4 (en) | 2003-03-06 | 2008-01-09 | Accera Inc | NOVEL CHEMICAL ENTITIES AND METHODS OF USE IN THE TREATMENT OF METABOLIC DISORDERS |
US20060280721A1 (en) | 2003-06-03 | 2006-12-14 | The Gov Of Usa Represented By Secretary Of Dpt Of | Nutritional supplements and therapeutic compositions comprising (r)-3- hydroxybutyrate derivatives |
US20050013884A1 (en) | 2003-07-16 | 2005-01-20 | Rennels M. Scott | Compositions and methods for treating heart disease |
US7148192B2 (en) * | 2004-01-29 | 2006-12-12 | Ebwe Pharma Ges. M.H. Nfg.Kg | Neuroprotective dietary supplement |
US20060252775A1 (en) | 2005-05-03 | 2006-11-09 | Henderson Samuel T | Methods for reducing levels of disease associated proteins |
US8227408B2 (en) | 2005-09-07 | 2012-07-24 | Neurotez, Inc. | Leptin as an anti-amyloidogenic biologic and methods for delaying the onset and reducing Alzheimer's disease-like pathology |
RU2437656C2 (ru) * | 2005-12-15 | 2011-12-27 | Нестек С.А. | Композиции и способы для сохранения функции головного мозга |
PT2001293T (pt) | 2006-04-03 | 2018-11-28 | Accera Inc | Utilização de compostos cetogénicos para tratamento de comprometimento da memória associado à idade |
US7807718B2 (en) | 2006-06-30 | 2010-10-05 | Sami A. Hashim | Glyceride esters for the treatment of diseases associated with reduced neuronal metabolism of glucose |
-
2007
- 2007-04-03 PT PT07797196T patent/PT2001293T/pt unknown
- 2007-04-03 KR KR1020087010466A patent/KR20090003148A/ko active Application Filing
- 2007-04-03 EP EP07797196.8A patent/EP2001293B9/en active Active
- 2007-04-03 SI SI200732064T patent/SI2001293T1/sl unknown
- 2007-04-03 PT PT121605992T patent/PT2500017T/pt unknown
- 2007-04-03 EP EP12160599.2A patent/EP2500017B1/en active Active
- 2007-04-03 LT LTEP07797196.8T patent/LT2001293T/lt unknown
- 2007-04-03 JP JP2009504423A patent/JP2009532496A/ja active Pending
- 2007-04-03 US US12/064,850 patent/US8124589B2/en not_active Expired - Fee Related
- 2007-04-03 ES ES07797196T patent/ES2697504T3/es active Active
- 2007-04-03 HU HUE12160599A patent/HUE035852T2/en unknown
- 2007-04-03 DK DK12160599.2T patent/DK2500017T3/da active
- 2007-04-03 DK DK07797196.8T patent/DK2001293T3/en active
- 2007-04-03 ES ES12160599.2T patent/ES2645816T3/es active Active
- 2007-04-03 WO PCT/US2007/065873 patent/WO2007115282A2/en active Application Filing
- 2007-04-03 LT LTEP12160599.2T patent/LT2500017T/lt unknown
- 2007-04-03 KR KR1020157002435A patent/KR101634083B1/ko active Active
- 2007-04-03 HU HUE07797196A patent/HUE040002T2/hu unknown
-
2012
- 2012-01-25 US US13/358,257 patent/US8748400B2/en not_active Expired - Fee Related
- 2012-12-06 JP JP2012267035A patent/JP5847693B2/ja active Active
-
2014
- 2014-05-05 US US14/269,453 patent/US20140256808A1/en not_active Abandoned
-
2015
- 2015-11-25 JP JP2015229243A patent/JP2016121128A/ja not_active Withdrawn
-
2017
- 2017-12-18 JP JP2017241367A patent/JP2018080175A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DK2001293T3 (en) | 2018-11-19 |
ES2645816T3 (es) | 2017-12-07 |
US20120122978A1 (en) | 2012-05-17 |
KR101634083B1 (ko) | 2016-06-28 |
JP2009532496A (ja) | 2009-09-10 |
JP2016121128A (ja) | 2016-07-07 |
PT2500017T (pt) | 2017-11-14 |
WO2007115282A2 (en) | 2007-10-11 |
EP2001293B9 (en) | 2019-04-17 |
PT2001293T (pt) | 2018-11-28 |
KR20150018897A (ko) | 2015-02-24 |
DK2500017T3 (da) | 2017-11-06 |
WO2007115282A3 (en) | 2007-12-21 |
HUE040002T2 (hu) | 2019-02-28 |
EP2500017A1 (en) | 2012-09-19 |
LT2001293T (lt) | 2018-11-12 |
EP2001293A4 (en) | 2009-09-23 |
US8748400B2 (en) | 2014-06-10 |
JP5847693B2 (ja) | 2016-01-27 |
HUE035852T2 (en) | 2018-05-28 |
EP2001293B1 (en) | 2018-08-29 |
JP2018080175A (ja) | 2018-05-24 |
KR20090003148A (ko) | 2009-01-09 |
US20140256808A1 (en) | 2014-09-11 |
ES2697504T3 (es) | 2019-01-24 |
EP2500017B1 (en) | 2017-09-06 |
US8124589B2 (en) | 2012-02-28 |
US20080287372A1 (en) | 2008-11-20 |
SI2001293T1 (sl) | 2018-12-31 |
EP2001293A2 (en) | 2008-12-17 |
JP2013082716A (ja) | 2013-05-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
LT2001293T (lt) | Ketogeninių junginių panaudojimas su amžiumi susijusių atminties pažeidimų gydymui | |
IL248204A0 (en) | Combined treatment of tumors expressing 38cd | |
GB0610867D0 (en) | Treatment of pain | |
EP2066589A4 (en) | WATER TREATMENT SYSTEM | |
GB2454797B (en) | Treatment of wastewater | |
EP2046349A4 (en) | TREATMENT OF EXCESSIVE NEOVASCULARIZATION | |
IL193748A0 (en) | Treatment of pain | |
EP2049139A4 (en) | TREATMENT OF TUMORS EXPRESSING RAS | |
ZA201001264B (en) | 1-amino-alkylcycohxane derivatives for the treatment of cochleat tinnitus | |
GB0909297D0 (en) | Composition for the treatment of skin conditions | |
GB0715790D0 (en) | Drug combination for the treatment of sialorrhoea | |
IL192933A0 (en) | Benzoisoindole derivatives for the treatment of pain | |
GB0610868D0 (en) | Treatment of pain | |
EP2271328A4 (en) | ANTISEPTIC COMPOSITIONS FOR THE TREATMENT OF INFECTIONS | |
IL194066A0 (en) | Therapeutic composition for treatment of tinnitus | |
GB0723100D0 (en) | Treatment of HFnEF | |
EP2023894A4 (en) | FIXED COMBINATION DOSAGE FOR TREATING MIGRAINE | |
GB0616450D0 (en) | Treatment of pain | |
GB0624439D0 (en) | Technique for treatment of gall-and kidney-stones | |
IL184620A0 (en) | Composition for the treatment of inflammation | |
PL1879609T3 (pl) | Zastosowanie histonu w celach terapeutycznych | |
IL176303A0 (en) | Pharmaceutical composition for the treatment of otomycosis | |
GB0602857D0 (en) | The treatment of sialorrhoea | |
ZA200806180B (en) | Benzoisoindole derivatives for the treatment of pain | |
GB0609789D0 (en) | Treatment of inflammation |