JPH08225428A - Cosmetic - Google Patents

Abstract

PURPOSE: To obtain a cosmetic having excellent stability and safety and exhibiting synergistic effect for remarkably suppressing the formation of wrinkles by combining a specific plant extract with a pseudoceramide. CONSTITUTION: This cosmetic contains (A) an extract of one or more kinds of plants selected from among hamamelis, SHOUKYOU (rhizome of Zingiber officinale) and SENKIN and (B) a pseudoceramide of formula (R<1> and R<2> are each a 9-39C straight or branched-chain saturated or unsaturated hydrocarbon group for which one or more OH groups may be substituted; R<3> and R<4> are each H, a phosphate residue, a sulfate residue or a saccharide residue). The cosmetic is preferably further incorporated with (C) a sterol, (D) an anti- inflammatory substance or (E) one or more substances selected from between a singlet oxygen scavenger and an antioxidant. The amounts of the components A, B, C, D and E are preferably 0.0001-20wt.% (in terms of dry solid), 0.01-50wt.%, 0.01-50wt.%, 0.001-5wt.% and 0.001-5wt.%, respectively.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cosmetic having an excellent effect of suppressing wrinkle formation.

[0002]

2. Description of the Related Art Maintaining healthy and beautiful skin has become a serious concern for people of all ages. However, the skin is affected by aging, ultraviolet rays, temperature / humidity, diseases, stress, eating habits, etc., causing aging, deterioration of various functions, and various other troubles.

Of these, wrinkles, which are one of the problems of the dermis, are aging of the skin due to aging and sunlight (photoaging).
Caused by. Although the mechanism of aging is not clear, in the case of the skin, it is located in the outermost layer of the body and plays a role of the front line of biological defense.Accordingly, the accumulation of disorders due to environmental factors has a significant effect on the skin aging phenomenon. it seems to do. In particular, ultraviolet rays are considered to be the largest environmental factor involved in skin aging and wrinkle formation. That is, it is known that free radicals (particularly active oxygen) produced by ultraviolet rays induce not only acute inflammation such as sunburn but also photoaging by being chronically repeated. In detail,
Various free radicals and active oxygen (superoxide, hydroxy radicals, singlet oxygen, etc.) generated by ultraviolet rays are DNA-protein crosslinks (crosslinking bonds) in the dermal component, obstacles and denaturation of protein crosslinks such as collagen and elastin, and SOD. It is thought that the inactivation of antioxidant enzymes such as the above, the peroxidation of membrane lipids of cell components and the resulting deterioration of cell function, resulting in the formation of aging and wrinkles (Fragrance Journal, Vol. 11, Vol. 49
-54, 1992).

With the recent increase in the proportion of elderly people in the makeup population, there is a demand for cosmetics which suppress such skin aging, especially wrinkle formation.

Conventionally, as preventive / improving agents for wrinkle formation, retinoic acid and its derivatives (JP-A-6-24958, etc.) and ascorbic acid derivatives (JP-A-61-305).
No. 10, JP-A-61-152613, etc.), Vitamin E (JP-A-62-19511, JP-A-62).
-87506) and γ-amino acid derivatives (JP-A-62-255405, JP-A-2-62810, etc.) have already been proposed.

[0006] However, these are not satisfactory in stability, safety and effect, especially in the effect of suppressing wrinkle formation.

[0007]

SUMMARY OF THE INVENTION Therefore, an object of the present invention is to provide a cosmetic having an excellent effect of suppressing wrinkle formation.

[0008]

In view of such circumstances, the present inventors have examined the wrinkle formation-inhibiting action of various natural products and compounds, and as a result, combined a specific plant extract and pseudoceramides. It was found that a cosmetic composition having an excellent effect of suppressing wrinkle formation can be obtained by using it, and the present invention has been completed.

That is, the present invention provides the following components (A) and (B): (A) an extract of one or more kinds of plants selected from hamamelis, button, ginger and sensi, (B)
The following general formula (1)

[0010]

Embedded image

(In the formula, R ¹ and R ² are the same or different and are linear or branched, saturated or unsaturated carbonization having 9 to 39 carbon atoms which may be substituted with one or more hydroxyl groups. A hydrogen atom group, and R ³ and R ⁴ are the same or different and each represents a hydrogen atom, a phosphate residue, a sulfate residue or a sugar residue) To do.

The plant extract of the component (A) used in the present invention is hamamelis, button, ginger, sensi,
Gentian, Chickweed grass, Catalpa, Parsley, Sweet tea, Amami, Rensai, Rensai, Persimmon leaf, Floating grass, Life-prolonging grass, Thyme, Kawamoyogi, Ginkgo biloba, Owakaku, Ouren, Kyoukou, Kikuka, Kyounin, Kumazasa, Gardenia, Dokudami, White birch , Achillea millefolium, senkyu, mulberry, chimpanzee, daffodil, tonin, novara, safflower,
It is obtained from a plant selected from Atlantic peppermint, horse chestnut, sorghum, peach leaves, cornflower, lily, yokuinin, litchi and forsythia. Of these,
Hamamelis, button, ginger and senki are particularly preferred.

The extract is obtained by drying or crushing whole plant of each plant or its leaves, bark, roots, branches, etc. at one or two or more places (hereinafter referred to as "prodrug"), or It can be obtained by extracting with a solvent at room temperature or under heating, or by using an extraction device such as a Soxhlet extractor. Here, the solvent used is not particularly limited, and examples thereof include water, primary alcohols such as methyl alcohol and ethyl alcohol, propylene glycol, and 1,3-.
Liquid polyhydric alcohols such as butylene glycol, lower alkyl esters such as acetic acid ethyl ester, hydrocarbons such as benzene and hexane, known solvents such as ethyl ether and acetone, and these solvents may be used alone or in combination of two or more. It can be used in combination. As a specific example of a preferable extraction method from the drug substance, 1000 ml of 50 v / v% ethanol is added to 100 g of the dried and ground product, and extraction is performed for 3 days at room temperature with occasional stirring. The extract thus obtained is filtered, the filtrate is allowed to stand at 5 ° C. for 3 days and then filtered again to obtain a supernatant. The plant extract obtained under the above conditions may be used as it is as an extracted solution, but if necessary, it may be subjected to treatments such as concentration, filtration and drying.

The plant extract of the component (A) can be used alone or in combination of two or more kinds, and the compounding amount thereof is not particularly limited, but it is converted to a dry solid content, and the total amount of the composition is 0.
It is preferable to add 0001 to 20% by weight, and in particular, it is preferable that the content is 0.
It is preferable to add 0001 to 10% by weight, more preferably 0.0001 to 5% by weight, in order to obtain a sufficient effect of preventing and improving wrinkle formation.

The component (B) pseudo-ceramides used in the present invention are represented by the above general formula (1). Where:
Examples of the linear or branched saturated or unsaturated hydrocarbon group having 9 to 39 carbon atoms represented by R ¹ and R ² include nonyl group, decyl group, undecyl group, dodecyl group, tridecyl group, tetradecyl group, Pentadecyl group, hexadecyl group, heptadecyl group, octadecyl group, nonadecyl group,
Eicosyl group, heneicosyl group, docosyl group, tricosyl group, tetracosyl group, pentacosyl group, hexacosyl group, 2-heptylundecyl group, 5,7,7-trimethyl-2- (1,3,3-trimethylbutyl) -octyl Group, 2-hexyldecyl group, 2-octylundecyl group, 2-decyltetradecyl group, and other alkyl groups; decenyl group, dodecenyl group, undecenyl group, tridecenyl group, tetradecenyl group, pentadecenyl group, hexadecenyl group, heptadecenyl group, Octadecenyl group, nonadecenyl group, eicosenyl group, heneicosenyl group, docosenyl group, tricosenyl group, tetracosenyl group, pentacosenyl group, hexacocenyl group, nonadienyl group, decadienyl group, dodecadienyl group, undecadienyl group,
Tridecadienyl group, tetradecadienyl group, pentadecadienyl group, hexadecadienyl group, heptadecadienyl group, octadecadienyl group, nonadecadienyl group,
Icosadienyl group, henicosadienyl group, docosadienyl group, tricosadienyl group, tetracosadienyl group,
Examples thereof include a pentacosadienyl group, a hexacosadienyl group, a 9-octadecenyl group, and a 9,12-octadecadienyl group. These hydrocarbon groups may be substituted with one or more hydroxyl groups.

Of these, R ¹ and R ² are preferably an alkyl group having 8 to 28 carbon atoms which may be substituted with a hydroxyl group.

Pseudo-ceramides represented by the general formula (1) are described in, for example, JP-A-62-128048 and JP-A-6-28048.
It can be manufactured according to the method described in JP-A-3-216852. Particularly preferred as the pseudo-ceramide (1) is N- (3-tetradecyloxy-2-
Hydroxypropyl) -N-2-hydroxyethyldecanamid, N- (3-hexadecyloxy-2-hydroxypropyl) -N-2-hydroxyethylhexadecanamide, N- (3-hexadecyloxy-2 -Hydroxypropyl) -N-2-hydroxyethyl decanamide.

The pseudo-ceramides as the component (B) are preferably added in an amount of 0.01 to 50% by weight in the total composition, and particularly preferably 0.
It is preferable to add 1 to 40% by weight, more preferably 0.1 to 20% by weight in order to obtain a sufficient wrinkle formation preventing and improving effect.

The cosmetic of the present invention comprises, in addition to the above essential ingredients,
Furthermore, if the following components (C), (D) or (E) are added,
The effects of the present invention can be further enhanced.

When sterols are blended as the component (C), penetration of the components (A) and (B) into the skin is enhanced,
This is preferable because a higher effect of preventing and improving wrinkle formation can be obtained. Examples of such sterols include cholesterol or a cholesterol derivative, and examples of the cholesterol derivative include cholesteryl alkenylsuccinate, cholestanol, a saturated or unsaturated straight chain or branched chain having 12 to 36 carbon atoms, preferably 14 to 28 carbon atoms. Examples thereof include cholesteryl ester having a chain hydrocarbon group, dehydrocholesterol and the like. Among these, cholesteryl alkenyl succinate is synthesized by the production method described in JP-A-5-294989, for example, n-hexadecenyl succinic acid cholesteryl monoester, n-octadecenyl succinic acid cholesteryl ester. Examples thereof include monoesters.
Examples of the cholesteryl ester include cholesteryl isostearate, cholesteryl 1,2-hydroxystearate, lanolin fatty acid cholesteryl, and cholesteryl ricinoleate. Of these, alkenyl succinate cholesteryl, cholesterol and cholesteryl isostearate are preferred.

The sterols as the component (C) are one kind or two kinds.
It is possible to use a combination of two or more species, and the blending amount is not particularly limited, but it is preferably blended in an amount of 0.01 to 50% by weight, more preferably 0.01 to 40.0% by weight, and further 0.1. It is preferably set to 01 to 20.0% by weight.

Further, it is preferable to add an anti-inflammatory substance as the component (D) because the effect of suppressing inflammation caused by ultraviolet rays and the like is enhanced and a higher effect of preventing and improving wrinkle formation is obtained. Examples of such anti-inflammatory substances include glycyrrhizic acid and salts thereof, glycyrrhetinic acid and salts thereof, epsilon aminocaproic acid and salts thereof, allantoin, lysozyme chloride, guaiazulene, methyl salicylate, γ
-Oryzanol and the like are mentioned, and of these, glycyrrhetinic acid and glycyrrhetinic acid stearyl epsilon aminocaproic acid are preferable.

The anti-inflammatory substance of the component (D) may be used alone or in combination of two or more, and may be 0.00
It is preferable to add 1 to 5% by weight, particularly 0.01 to 2
It is preferable to add 0.01% to 1% by weight, more preferably 0.01 to 1% by weight.

Furthermore, when a singlet oxygen scavenger or an antioxidant is added as the component (E), the effect of detoxifying the peroxide and active oxygen is enhanced, and a higher effect of preventing and improving wrinkle formation can be obtained. preferable. Examples of the singlet oxygen scavenger or antioxidant include, for example, α-carotene, β-carotene, γ-carotene, lycopene, clybutoxanthin, lutein, zeaxanthin, isoseaxanthin, rhodoxanthin,
Carotenoids such as capsanthin and crocetin; 1,4-
Diazacyclooctane, 2,5-dimethylfuran, 2-
Methylfuran, 2,5-diphenylfuran, 1,3-diphenylisobenzofuran, α-tocopherol, β-tocopherol, γ-tocopherol, d-tocopherol, histidine, tryptophan, methionine, alanine or an alkyl ester thereof; dibutylhydroxytoluene,
Tannins such as butylhydroxyanisole, ascorbic acid, tannic acid, epicatechin, epicarocatechin, epicatechin gallate, epicarocatechin gallate,
Examples thereof include flavonoids such as rutin. Of these, carotene, tocopherol, ascorbic acid, tannic acid, epicatechin gallate, and epicarocatechin gallate are preferable.

The singlet oxygen scavenger or antioxidant of the component (E) can be used alone or in combination of two or more,
It is preferable to add 0.001 to 5% by weight in the total composition, particularly 0.01 to 2% by weight, and further 0.01 to 1% by weight.
It is preferable to mix them.

In the cosmetic of the present invention, one or more of these components (C), (D) and (E) can be used in combination.

The cosmetic of the present invention further comprises oily ingredients, water, surfactants and other ingredients usually used in cosmetics to prepare an emulsion type,
It can be made into a desired dosage form such as a dispersion type, a two-layer type, a solubilization type and a gel, and can be a lotion, an emulsion, a cream, a pack, a foundation and the like.

Examples of the oil component include hydrocarbons such as solid or liquid paraffin, petrolatum, crystal oil, ceresin, ozokerite, montan wax, squalane, squalene, olive oil, carnauba wax, lanolin, jojoba oil, glycerin monostearate ester, Glycerin distearate, glycerin monooleate, isopropyl stearate, ester oil such as neopentyl glycol dicaprate, higher fatty acids such as stearic acid and palmitic acid, and higher alcohols such as cetanol and stearyl alcohol can be used. . When these oils are blended, it is preferably blended in the cosmetic in an amount of 0.01 to 50% by weight, particularly preferably 0.1 to 30% by weight.

Water can be used as a base together with ethanol and a water-soluble polyhydric alcohol. As the water-soluble polyhydric alcohol, one containing two or more hydroxyl groups in the molecule, for example, ethylene glycol, propylene glycol, 1,3-butylene glycol, 1,4-
Butylene glycol, dipropylene glycol, glycerin and polyglycerin such as diglycerin, triglycerin, tetraglycerin, glucose, maltose, maltitol, sucrose, fructose, xylitol, sorbitol, maltotriose, threitol, erythritol, starch-reducing sugar reduction Examples thereof include alcohols, and one or more of these can be used.
When these water, ethanol, and water-soluble polyhydric alcohol are blended, the blending amount in the cosmetic can be appropriately set according to the dosage form, but usually the sum of these is 0.0
It is preferable to add 1 to 75% by weight, and particularly preferably 0.1 to 50% by weight.

When the cosmetic of the present invention is emulsified or solubilized, it is preferable to add a surfactant. Examples of the surfactant include polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene sorbitol fatty acid ester, glycerin fatty acid ester, polyoxyethylene hydrogenated castor oil alkyl sulfate, polyoxyethylene. Examples thereof include ethylene alkyl sulfate ester, alkyl phosphate ester, polyoxyethylene alkyl phosphate ester, fatty acid alkali metal salt, sorbitan fatty acid ester, glycerin fatty acid ester, and alkyl glyceryl ether. These may be used alone or in combination. it can. When these surfactants are blended, it is preferably blended in the cosmetic in an amount of 0.01 to 50% by weight, particularly preferably 0.1 to 30% by weight.

The cosmetic of the present invention may further contain silicones as an oil agent or a surfactant. The silicones are not particularly limited as long as they are usually blended in cosmetics, for example, octamethylpolysiloxane, tetradecamethylpolysiloxane,
Methyl polysiloxane, highly polymerized methyl polysiloxane,
In addition to methylphenylpolysiloxane, octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, and other methylpolycyclosiloxanes, trimethylsiloxysilicic acid, and further polyether-modified silicone, polyether-alkyl-modified silicone, alkylglycerylether-modified silicone And the like modified silicone and the like. When blending these silicones, the blending amount in the cosmetic is such as dimethylpolysiloxane, when used as an oil component, when using as a surfactant such as polyether modified silicone, when a non-silicone oil component or It may be adjusted so that the total amount with the surfactant is the above-mentioned amount.

A powder is further added to the cosmetic of the present invention,
It can be used as makeup cosmetics such as foundation. As the powder, for example, mica, talc, sericite, kaolin, nylon powder, extender pigments such as polymethylsilsesquioxane, inorganic pigments such as pearls,
Examples thereof include organic pigments such as red 202, red 226, yellow 4, and aluminum lake, and inorganic powder for protecting ultraviolet rays such as zinc oxide, titanium oxide, zirconium oxide, and iron oxide. These powders are treated with silicone such as methylhydrogenmethylpolysiloxane, trimethylsiloxysilicic acid and methylpolysiloxane, fluorine treatment with perfluoroalkyl phosphate ester, perfluoroalcohol and the like, amino acid treatment with N-acylglutamic acid and the like, Those treated with lecithin, metal soap, fatty acid, alkyl phosphate, etc. can also be used. When these powders are blended, the blending amount in the cosmetic can be appropriately set according to the dosage form, but it is usually preferable to blend 0.1 to 50% by weight, particularly 1 to 30% by weight. It is preferable to mix them.

The cosmetic composition of the present invention may further contain a pH adjuster to improve the stability of color and odor of the ingredients such as plant extract. The pH adjuster is not particularly limited, but metal hydroxides such as sodium hydroxide, potassium hydroxide and lithium hydroxide, triethanolamine,
Isopropanolamine, diisopropanolamine,
Organic acids such as urea, ε-aminocaproic acid, sodium pyrrolidonecarboxylate, sodium hydrogenphosphate, sodium citrate, citric acid, lactic acid, succinic acid, tartaric acid, etc.
Examples thereof include betaines such as glycine betaine and lysine betaine. The pH of the cosmetic of the present invention is preferably in the range of 4-10.

In addition to the above-mentioned components, the cosmetic of the present invention may contain various components which are usually added to cosmetics, quasi drugs, pharmaceuticals, etc. within a range not impairing the object of the present invention. . Examples of such components include inorganic salts such as magnesium sulfate, potassium sulfate, sodium sulfate, magnesium chloride, sodium chloride; polyvinyl alcohol, carboxyvinyl polymer, carboxymethylcellulose, gelatin, tragacanth gum, xanthan gum, hyaluronic acid, tuberose extract, Viscosity modifiers such as agarose and sodium alginate; antiseptics such as parabens, ultraviolet absorbers, dyes, medicinal ingredients, and fragrances.

[0035]

EFFECTS OF THE INVENTION The cosmetic composition of the present invention is used in combination with a specific plant extract and pseudoceramides to obtain a recurrently high effect of suppressing wrinkle formation.

[0036]

The present invention will be described in more detail with reference to examples, but the present invention is not limited to these examples.

Production example of plant extract

Production Example 1 Method for producing hamamelis extract 50 per 100 g of dried crushed hamamelis leaves and bark
Add 1,000 ml of v / v% ethanol and perform extraction for 3 days at room temperature with occasional stirring. The obtained extract is filtered,
The filtrate was allowed to stand at 5 ° C. for 3 days and then filtered again to obtain a supernatant.

Production Example 2 Production Method of Button Extract Instead of the dried and ground product of Hamamelis in Production Example 1,
It was produced in the same manner as in Production Example 1, except that a dried and crushed root bark was used.

Production Example 3 Production Method of Ginger Extract: Instead of the dried pulverized product of Hamamelis in Production Example 1,
Production Example 1 except that a dry ground product of ginger rhizome was used
It was manufactured in the same manner as.

Production Example 4 Production Method of Senxi Extract Instead of the dried and ground product of Hamamelis in Production Example 1,
Production Example 1 except that a dry ground product of whole grass of Senxi was used
It was manufactured in the same manner as. These extracts were produced so that the dry solid content was 0.1 to 20%.

Example 1 Emulsified cosmetics having the compositions shown in Table 1 below were produced by a conventional method, and the effect of suppressing wrinkle formation when these were used was evaluated by the following method. Table 2 shows the results.

(Evaluation Method) An emulsion type cosmetic (80 μl) was applied to hairless mice. After 2 hours, UV-B (1
MED or less), and immediately after that, another sample was applied. This operation was performed 5 times a week for 16 weeks. The amount of irradiation energy is UV-Radiometer (Tok
yo optical, UV-R-305 / 365 days)
The total irradiation dose is 100 m at an energy dose of 0.28 mW / cm ² so that the irradiation dose per time is 1 MED or less.
It was set to J / cm ² . After completion of application / irradiation for 16 weeks, the frequency of the wrinkles formed was visually evaluated by the following criteria (wrinkle index).

Standard (wrinkle index): 1: No wrinkles formed. 2: Slightly formed wrinkles. 3: Some wrinkles formed. 4: Strongly formed wrinkles.

[0045]

[Table 1]

[0046]

[Table 2]

Example 2 (o / w type moisturizing emulsion) An o / w type moisturizing emulsion having the following composition was produced by a conventional method.

[0048]

[Table 3] (Composition) (wt%) Compound 1 (same as in Example 1) 3.0 Hamamelis extract ^{* 2} 0.5 Button extract ^{* 1} 0.5 Cetyl alcohol 1.0 Vaseline 2.0 Squalane 5 0.0 Dimethyl polysiloxane (6 cSt) 2.0 Glycerin 4.0 1,3-Butylene glycol 2.0 Polyoxyethylene (20) sorbitan monooleate 0.5 sorbitan monostearate 0.3 Tuberose polysaccharide (1% solution) ) 5.0 n-hexadecenyl succinic acid cholesteryl monoester 1.0 stearyl glycyrrhetinate 1.0 tocopherol 1.0 succinic acid 0.55 sodium dihydrogen phosphate 0.9 purified water residual amount 100.0 * 1: Button extract (extract described in Production Example 2, solid content 0.5%) * 2: Hamamelis extract (extract described in Production Example 1, solid content 1.0%) )

The obtained emulsion was excellent in the wrinkle formation inhibiting action.

Example 3 (Sunscreen emulsion) A sunscreen emulsion having the following composition was produced by a conventional method.

[0051]

(Table 4) (Composition) (wt%) Compound 1 (same as in Example 1) 2.0 Hamamelis extract ^{* 2} 0.5 Button extract ^{* 1} 0.5 Octyl paramethoxycinnamate 6.0 4- tert-butyl-4-methoxybenzoylmethane 2.0 oleyl oleate 5.0 dimethylpolysiloxane (6 cSt) 3.0 vaseline 0.5 cetyl alcohol 1.0 sorbitan sesquioleate 0.8 polyoxyethylene (20) oleyl Alcohol ether 1.2 Dipropylene glycol 6.0 Ethanol 3.0 Hydroxyethyl cellulose 0.3 n-Octadecenyl succinic acid cholesteryl monoester 1.0 Stearyl glycyrrhetinate 1.0 Tocopherol 1.0 Succinic acid 0.2 Water sodium oxide 0.2 purified water Balance total 100.0 * 1: button extract (production example Extract according solids 0.5%) * 2: Hamamelis extract (extract of Production Example 1, solids 1.0%)

The obtained emulsion was excellent in the effect of suppressing wrinkle formation.

Example 4 A sunscreen cream having the composition shown below was prepared according to Example 3
It was manufactured in the same manner as. The obtained cream was excellent in the effect of preventing skin aging.

[0054]

[Table 5] (Composition) (wt%) Compound 1 (same as in Example 1) 3.0 Silicone-coated zinc oxide 7.0 2-ethylhexyl p-methoxycinnamate 2.0 Ascorbic acid 0.5 Cholesterol 1.0 Polyether-modified silicone ^{* 5} 2.5 Methyl polysiloxane ^{* 6} 6.0 Cyclic silicone ^{* 7} 12.0 Magnesium sulfate 0.7 Allantoin 0.1 Ginger extract ^{* 3} 0.5 Senxy extract ^{* 4} 0.5 Glycerin 3.0 Preservative Suitable amount of purified water Residual amount meter 100.0 * 3: Ginger extract (extract described in Production Example 3, dry solid content 2.0% * 4: Senxy extract (described in Production Example 4) Extraction, dry solid content 0.5%) * 5: Silicone KF-6015, manufactured by Shin-Etsu Chemical Co., Ltd. * 6: Silicone KF-96A (6cs), manufactured by Shin-Etsu Chemical Co., Ltd. * 7: Silicone SH- 244, SH-245 or SH-244 and SH-245 3: 2 (weight ratio) Compounds, manufactured by Dow Corning Toray Silicone Co., Ltd.

The emulsion obtained was excellent in the effect of suppressing wrinkle formation.

 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Ritsuko Toyota 1926-55 Hirayama-cho, Midori-ku, Chiba-shi, Chiba

Claims (9)

[Claims] 1. The following components (A) and (B): (A) an extract of one or more kinds of plants selected from hamamelis, button, ginger and senki; (B)
The following general formula (1) (In the formula, R ¹ and R ² are the same or different and have 9 to 9 carbon atoms which may be substituted with one or more hydroxyl groups.
39 represents a straight chain or branched chain saturated or unsaturated hydrocarbon group, and R ³ and R ⁴ are the same or different and represent a hydrogen atom, a phosphate residue, a sulfate residue or a sugar residue) Cosmetics containing pseudo-ceramides represented by. 2. The cosmetic according to claim 1, which further comprises (C) a sterol. 3. The cosmetic according to claim 1, further comprising (D) an anti-inflammatory substance. 4. The cosmetic according to claim 1, which further comprises (E) one or more selected from singlet oxygen scavengers and antioxidants. 5. The cosmetic according to claim 1, wherein the content of the plant extract of the component (A) is 0.0001 to 20% by weight in terms of dry solid content. 6. The component (B) containing pseudoceramides in an amount of 0.01 to
50% by weight is contained, The cosmetics of Claim 1 characterized by the above-mentioned. 7. The sterol as the component (C) is one or more selected from cholesteryl alkenylsuccinate, cholesterol and cholesteryl isostearate, and the sterol content is 0.01 to 50% by weight. The cosmetic according to claim 2, which is 8. The anti-inflammatory substance of component (D) is one or more selected from glycyrrhetinic acid, stearyl glycyrrhetinate and epsilon aminocaproic acid, and the content of the anti-inflammatory substance is 0.001 to 5% by weight. %, The cosmetic according to claim 3. 9. The singlet oxygen scavenger or antioxidant of component (E) is carotene, tocopherol, ascorbic acid,
One or more selected from tannic acid, epicatechin gallate and epicarocatechin gallate, and the content of singlet oxygen scavenger or antioxidant is 0.001-
The cosmetic according to claim 4, which is 5% by weight.