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ID28276A - Heterolingkar nitrogen bisiklik - Google Patents

Heterolingkar nitrogen bisiklik

Info

Publication number
ID28276A
ID28276A IDW20010903A ID20010903A ID28276A ID 28276 A ID28276 A ID 28276A ID W20010903 A IDW20010903 A ID W20010903A ID 20010903 A ID20010903 A ID 20010903A ID 28276 A ID28276 A ID 28276A
Authority
ID
Indonesia
Prior art keywords
lower alkyl
heteroaryl
aryl
cycloalkyl
alkyl
Prior art date
Application number
IDW20010903A
Other languages
English (en)
Indonesian (id)
Inventor
William Harris
Christopher Huw Hill
Ian Edward David Smith
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26314565&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ID28276(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9823277.0A external-priority patent/GB9823277D0/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ID28276A publication Critical patent/ID28276A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Inorganic Insulating Materials (AREA)
IDW20010903A 1998-10-23 1999-10-13 Heterolingkar nitrogen bisiklik ID28276A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9823277.0A GB9823277D0 (en) 1998-10-23 1998-10-23 Bicycle nitrogen heterocycles
GBGB9920044.6A GB9920044D0 (en) 1998-10-23 1999-08-24 Biciclic nitrogen heterocycles

Publications (1)

Publication Number Publication Date
ID28276A true ID28276A (id) 2001-05-10

Family

ID=26314565

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20010903A ID28276A (id) 1998-10-23 1999-10-13 Heterolingkar nitrogen bisiklik

Country Status (25)

Country Link
US (1) US6150373A (zh)
EP (1) EP1123295B1 (zh)
JP (1) JP3593035B2 (zh)
CN (1) CN1150195C (zh)
AT (1) ATE277931T1 (zh)
AU (1) AU769989B2 (zh)
BR (1) BR9914677A (zh)
CA (1) CA2347474C (zh)
CZ (1) CZ20011394A3 (zh)
DE (1) DE69920732T2 (zh)
ES (1) ES2228123T3 (zh)
HK (1) HK1041483B (zh)
HR (1) HRP20010274A2 (zh)
HU (1) HUP0104199A3 (zh)
ID (1) ID28276A (zh)
MA (1) MA27678A1 (zh)
MY (1) MY126478A (zh)
NO (1) NO318802B1 (zh)
NZ (1) NZ510760A (zh)
PL (1) PL347432A1 (zh)
PT (1) PT1123295E (zh)
RU (1) RU2256662C2 (zh)
TR (1) TR200101102T2 (zh)
TW (1) TWI227235B (zh)
WO (1) WO2000024744A1 (zh)

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AR017219A1 (es) 1997-12-19 2001-08-22 Smithkline Beecham Corp Derivados de imidazol 1,4,5 sustituidos, composiciones que los comprenden, procedimiento para la preparacion de dichos derivados, uso de los derivados parala manufactura de un medicamento
US20040044012A1 (en) * 1998-05-26 2004-03-04 Dobrusin Ellen Myra Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation
US6858617B2 (en) 1998-05-26 2005-02-22 Smithkline Beecham Corporation Substituted imidazole compounds
ATE402177T1 (de) 1998-05-26 2008-08-15 Warner Lambert Co Bicyclische pyrimidine und bicyclische 3,4- dihydropyrimidine als inhibitoren der zellvermehrung
EP1112070B1 (en) 1998-08-20 2004-05-12 Smithkline Beecham Corporation Novel substituted triazole compounds
WO2000025791A1 (en) 1998-11-04 2000-05-11 Smithkline Beecham Corporation Pyridin-4-yl or pyrimidin-4-yl substituted pyrazines
TR200201058T2 (tr) 1999-10-21 2002-07-22 F.Hoffmann-La Roche Ag P38 protein kinaz inhibitörleri olarak, alkilaminoyla ornatılmış bisiklik, azotlu heterosikller
CZ20021744A3 (cs) * 1999-10-21 2002-08-14 F. Hoffmann-La Roche Ag Bicyklické dusíkové heterocykly substituované heteroalkylaminoskupinou jako inhibitory P38 proteinkinázy
US7053099B1 (en) 1999-11-23 2006-05-30 Smithkline Beecham Corporation 3,4-dihydro-(1H)quinazolin-2-one compounds as CSBP/p38 kinase inhibitors
US6759410B1 (en) * 1999-11-23 2004-07-06 Smithline Beecham Corporation 3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors
US7053098B1 (en) 1999-11-23 2006-05-30 Smithkline Beecham Corporation 3,4-Dihydro-(1H) quinazolin-2-one compounds as CSBP/P38 kinase inhibitors
DE60023025T2 (de) 1999-11-23 2006-07-13 Smithkline Beecham Corp. 3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p39-kinase-inhibitoren
US7101869B2 (en) 1999-11-30 2006-09-05 Pfizer Inc. 2,4-diaminopyrimidine compounds useful as immunosuppressants
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US7235551B2 (en) * 2000-03-02 2007-06-26 Smithkline Beecham Corporation 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
ES2372028T3 (es) 2000-10-23 2012-01-13 Glaxosmithkline Llc Nuevo compuesto de 8h-pirido[2,3-d]pirimidin-7-ona trisustituida para el tratamiento de enfermedades mediadas por la csbp/p38 quinasa.
BR0208010A (pt) 2001-03-12 2004-12-21 Avanir Pharmaceuticals Composto de benzimidazol para modulação de ige e inibição de proliferação celular
US7119111B2 (en) * 2002-05-29 2006-10-10 Amgen, Inc. 2-oxo-1,3,4-trihydroquinazolinyl derivatives and methods of use
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TW200413381A (en) 2002-11-04 2004-08-01 Hoffmann La Roche Novel amino-substituted dihydropyrimido [4,5-d]pyrimidinone derivatives, their manufacture and use as pharmaceutical agents
US7098332B2 (en) 2002-12-20 2006-08-29 Hoffmann-La Roche Inc. 5,8-Dihydro-6H-pyrido[2,3-d]pyrimidin-7-ones
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CN100577633C (zh) * 2003-04-23 2010-01-06 日本烟草产业株式会社 CaSR拮抗剂
EP1651648A4 (en) 2003-07-29 2009-09-02 Irm Llc COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
EP1768662A2 (en) 2004-06-24 2007-04-04 Novartis Vaccines and Diagnostics, Inc. Small molecule immunopotentiators and assays for their detection
ATE425166T1 (de) * 2004-08-31 2009-03-15 Hoffmann La Roche Amidderivate von 3-phenyldihydropyrimidoä4,5- düpyrimidinonen, deren herstellung und verwendung als pharmazeutische mittel
BRPI0514750A (pt) 2004-08-31 2008-06-24 Hoffmann La Roche derivados amida de 7-amino-3-fenil-diidropirimido[4, 5-d]pirimidinonas, sua fabricação e uso como inibidores de proteìna cinase
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US7897762B2 (en) * 2006-09-14 2011-03-01 Deciphera Pharmaceuticals, Llc Kinase inhibitors useful for the treatment of proliferative diseases
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CN102816162B (zh) * 2011-06-10 2016-04-27 中国科学院广州生物医药与健康研究院 嘧啶并嘧啶酮类化合物及其药用组合物和应用
GB201204384D0 (en) 2012-03-13 2012-04-25 Univ Dundee Anti-flammatory agents
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EP2968337B1 (en) 2013-03-15 2021-07-21 Celgene CAR LLC Heteroaryl compounds and uses thereof
US9321786B2 (en) 2013-03-15 2016-04-26 Celgene Avilomics Research, Inc. Heteroaryl compounds and uses thereof
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AU2015292818B2 (en) 2014-07-21 2020-01-16 Dana-Farber Cancer Institute, Inc. Imidazolyl kinase inhibitors and uses thereof
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US10851105B2 (en) 2014-10-22 2020-12-01 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
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US10308656B2 (en) * 2015-08-18 2019-06-04 Arizona Board Of Regents On Behalf Of The University Of Arizona Small molecule inhibitors of Ku70/80 and uses thereof
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CN115835908A (zh) 2019-10-14 2023-03-21 因赛特公司 作为fgfr抑制剂的双环杂环
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US5679683A (en) * 1994-01-25 1997-10-21 Warner-Lambert Company Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
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ATE402177T1 (de) * 1998-05-26 2008-08-15 Warner Lambert Co Bicyclische pyrimidine und bicyclische 3,4- dihydropyrimidine als inhibitoren der zellvermehrung

Also Published As

Publication number Publication date
EP1123295B1 (en) 2004-09-29
NO20011929L (no) 2001-04-19
HK1041483B (zh) 2004-12-24
CN1324360A (zh) 2001-11-28
HK1041483A1 (en) 2002-07-12
EP1123295A1 (en) 2001-08-16
JP2002528455A (ja) 2002-09-03
NO318802B1 (no) 2005-05-09
DE69920732T2 (de) 2006-02-23
CA2347474C (en) 2008-08-26
MY126478A (en) 2006-10-31
HUP0104199A3 (en) 2002-12-28
CZ20011394A3 (cs) 2001-12-12
NZ510760A (en) 2003-08-29
BR9914677A (pt) 2001-07-17
ATE277931T1 (de) 2004-10-15
MA27678A1 (fr) 2006-01-02
TWI227235B (en) 2005-02-01
PT1123295E (pt) 2005-01-31
CN1150195C (zh) 2004-05-19
AU1036300A (en) 2000-05-15
PL347432A1 (en) 2002-04-08
NO20011929D0 (no) 2001-04-19
HRP20010274A2 (en) 2002-06-30
US6150373A (en) 2000-11-21
JP3593035B2 (ja) 2004-11-24
DE69920732D1 (de) 2004-11-04
CA2347474A1 (en) 2000-05-04
ES2228123T3 (es) 2005-04-01
WO2000024744A1 (en) 2000-05-04
AU769989B2 (en) 2004-02-12
TR200101102T2 (tr) 2002-01-21
RU2256662C2 (ru) 2005-07-20
HUP0104199A2 (hu) 2002-04-29

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