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HUP0203773A2 - Epinastintartalmú oldatok - Google Patents

Epinastintartalmú oldatok

Info

Publication number
HUP0203773A2
HUP0203773A2 HU0203773A HUP0203773A HUP0203773A2 HU P0203773 A2 HUP0203773 A2 HU P0203773A2 HU 0203773 A HU0203773 A HU 0203773A HU P0203773 A HUP0203773 A HU P0203773A HU P0203773 A2 HUP0203773 A2 HU P0203773A2
Authority
HU
Hungary
Prior art keywords
epinastine
solutions containing
containing epinastine
conjunctiva
eosinophils
Prior art date
Application number
HU0203773A
Other languages
English (en)
Inventor
Gerold Duschler
Volker Trach
Original Assignee
Boehringer Ingelheim International Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7928843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0203773(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim International Gmbh. filed Critical Boehringer Ingelheim International Gmbh.
Publication of HUP0203773A2 publication Critical patent/HUP0203773A2/hu
Publication of HUP0203773A3 publication Critical patent/HUP0203773A3/hu
Publication of HU229502B1 publication Critical patent/HU229502B1/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F01MACHINES OR ENGINES IN GENERAL; ENGINE PLANTS IN GENERAL; STEAM ENGINES
    • F01LCYCLICALLY OPERATING VALVES FOR MACHINES OR ENGINES
    • F01L9/00Valve-gear or valve arrangements actuated non-mechanically
    • F01L9/20Valve-gear or valve arrangements actuated non-mechanically by electric means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/0318Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Detergent Compositions (AREA)

Abstract

A találmány tárgyát epinastint adott esetben racemátja, enantiomerevagy farmakológiailag elfogadható savaddíciós sója formájában,előnyösen epinastin-hidrokloridot, 0,005 és 0,5 mg/ml közöttkoncentrációban, valamint konzerválószert tartalmazó, fiziológiailagelfogadható puffer segítségével 6,5 és 7,2 közötti pH-értékrebeállított, helyileg alkalmazható vizes oldat képezi és annakalkalmazása a neutrofileknek és eozinofileknek a szem kötőhártya vagyaz orrnyálkahártya szövetébe való áramlásának gátlására. Ó
HU0203773A 1999-11-12 2000-10-14 Use of epinastine in the treatment of allergic rithinis/conjuctivitis HU229502B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19954516A DE19954516A1 (de) 1999-11-12 1999-11-12 Epinastin-haltige Lösungen
PCT/EP2000/010122 WO2001035962A1 (de) 1999-11-12 2000-10-14 Epinastin-haltige lösungen

Publications (3)

Publication Number Publication Date
HUP0203773A2 true HUP0203773A2 (hu) 2003-03-28
HUP0203773A3 HUP0203773A3 (en) 2005-01-28
HU229502B1 HU229502B1 (en) 2014-01-28

Family

ID=7928843

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0203773A HU229502B1 (en) 1999-11-12 2000-10-14 Use of epinastine in the treatment of allergic rithinis/conjuctivitis

Country Status (40)

Country Link
US (6) US20030050303A1 (hu)
EP (1) EP1231920B1 (hu)
JP (1) JP2003514021A (hu)
KR (1) KR100758842B1 (hu)
CN (1) CN1292752C (hu)
AR (1) AR026424A1 (hu)
AT (1) ATE353218T1 (hu)
AU (2) AU784017B2 (hu)
BG (1) BG65775B1 (hu)
BR (1) BR0015477A (hu)
CA (1) CA2391076C (hu)
CO (1) CO5251448A1 (hu)
CY (1) CY1106375T1 (hu)
CZ (1) CZ302483B6 (hu)
DE (2) DE19954516A1 (hu)
DK (1) DK1231920T3 (hu)
EA (1) EA006937B1 (hu)
EE (1) EE05395B1 (hu)
ES (1) ES2281359T3 (hu)
HK (1) HK1052303B (hu)
HR (1) HRP20020404B1 (hu)
HU (1) HU229502B1 (hu)
IL (2) IL149501A0 (hu)
ME (1) MEP36708A (hu)
MX (1) MXPA02004556A (hu)
MY (1) MY130441A (hu)
NO (1) NO329417B1 (hu)
NZ (1) NZ519425A (hu)
PE (1) PE20010826A1 (hu)
PL (1) PL198879B1 (hu)
PT (1) PT1231920E (hu)
RS (1) RS50173B (hu)
SA (1) SA01210658B1 (hu)
SI (1) SI1231920T1 (hu)
SK (1) SK287343B6 (hu)
TR (1) TR200201270T2 (hu)
TW (1) TWI225401B (hu)
UA (1) UA74563C2 (hu)
WO (1) WO2001035962A1 (hu)
ZA (1) ZA200203683B (hu)

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DE19954516A1 (de) * 1999-11-12 2001-05-17 Boehringer Ingelheim Int Epinastin-haltige Lösungen
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EP1468696A1 (en) * 2003-04-17 2004-10-20 Boehringer Ingelheim International GmbH Combinations of epinastine and antiphlogisitcs as new pharmaceutical compositions for the treatment of skin diseases
US20040247686A1 (en) * 2003-04-04 2004-12-09 Boehringer Ingelheim International Gmbh Pharmaceutical compositions comprising epinastine for the treatment of skin diseases
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure
JP2009500397A (ja) * 2005-07-08 2009-01-08 千寿製薬株式会社 エピナスチンを含む眼科用経皮吸収型製剤
WO2008098122A2 (en) * 2007-02-08 2008-08-14 Inspire Pharmaceuticals, Inc. Method for treating allergic rhinitis without adverse effects
US20080194544A1 (en) * 2007-02-08 2008-08-14 Ramesh Krishnamoorthy Aqueous formulations of epinastine for treating allergic rhinitis
US7378082B1 (en) 2007-11-05 2008-05-27 Inspire Pharmaceuticals, Inc. Method for treating allergic rhinitis without adverse effects
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TWI544922B (zh) 2011-05-19 2016-08-11 愛爾康研究有限公司 高濃度歐羅派特錠(olopatadine)眼用組成物
EP2630952A1 (en) * 2012-02-23 2013-08-28 Novagali Pharma S.A. Self-preserved oil dispersions comprising boric acid
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CN104491876A (zh) * 2014-12-23 2015-04-08 中国药科大学 含玻璃酸钠的依匹斯汀滴眼液及其制备方法
ITUB20153950A1 (it) * 2015-09-28 2017-03-28 Tred Srl Dispositivo nasale in grado di attivare il riflesso rino-palatale per l'igienizzazione rinofaringea
JP6134853B1 (ja) * 2016-10-28 2017-05-24 参天製薬株式会社 エピナスチン含有点眼液
JP6635974B2 (ja) * 2017-04-24 2020-01-29 参天製薬株式会社 エピナスチン含有点眼液
TW201841620A (zh) * 2017-05-01 2018-12-01 日商參天製藥股份有限公司 點眼劑
JP2019108320A (ja) * 2018-10-31 2019-07-04 参天製薬株式会社 ソフトコンタクトレンズの変質を抑制する眼科用組成物
JP7599838B2 (ja) * 2019-04-10 2024-12-16 参天製薬株式会社 エピナスチン又はその塩を含有する水性医薬組成物
JP6736752B2 (ja) * 2019-12-17 2020-08-05 参天製薬株式会社 エピナスチン含有点眼液
JP6963651B2 (ja) 2020-04-16 2021-11-10 参天製薬株式会社 エピナスチン又はその塩を含有する水性組成物
JP7118579B1 (ja) 2020-04-16 2022-08-16 参天製薬株式会社 エピナスチン又はその塩を含有する水性組成物
JP2020169213A (ja) * 2020-07-15 2020-10-15 参天製薬株式会社 エピナスチン含有点眼液
JP7114668B2 (ja) * 2020-10-08 2022-08-08 参天製薬株式会社 エピナスチン又はその塩を含有する花粉破裂抑制剤
CN115448927A (zh) * 2022-10-20 2022-12-09 重庆瑞泊莱医药科技有限公司 一种氢溴酸依匹斯汀晶型ii及其制备方法

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Also Published As

Publication number Publication date
HRP20020404B1 (hr) 2007-08-31
CN1292752C (zh) 2007-01-03
DK1231920T3 (da) 2007-04-10
AR026424A1 (es) 2003-02-12
US20070197503A1 (en) 2007-08-23
CO5251448A1 (es) 2003-02-28
US7429602B2 (en) 2008-09-30
IL149501A (en) 2012-04-30
SA01210658B1 (ar) 2006-11-05
HK1052303B (zh) 2007-04-13
US20030050303A1 (en) 2003-03-13
US20050288274A1 (en) 2005-12-29
EA200200492A1 (ru) 2002-10-31
NO329417B1 (no) 2010-10-18
AU2006201541A1 (en) 2006-05-11
EP1231920B1 (de) 2007-02-07
EE200200246A (et) 2003-06-16
WO2001035962A1 (de) 2001-05-25
US20070185082A1 (en) 2007-08-09
CA2391076C (en) 2008-06-17
CZ20021956A3 (cs) 2002-08-14
DE19954516A1 (de) 2001-05-17
CN1390129A (zh) 2003-01-08
EP1231920A1 (de) 2002-08-21
ZA200203683B (en) 2003-09-03
CY1106375T1 (el) 2011-10-12
DE50014041D1 (de) 2007-03-22
BG106681A (en) 2002-12-29
HRP20020404A2 (en) 2004-08-31
PL198879B1 (pl) 2008-07-31
IL149501A0 (en) 2002-11-10
NO20022201D0 (no) 2002-05-08
TWI225401B (en) 2004-12-21
ATE353218T1 (de) 2007-02-15
PL364028A1 (en) 2004-11-29
HUP0203773A3 (en) 2005-01-28
CA2391076A1 (en) 2001-05-25
KR100758842B1 (ko) 2007-09-19
BR0015477A (pt) 2002-06-25
NZ519425A (en) 2004-04-30
NO20022201L (no) 2002-05-08
BG65775B1 (bg) 2009-11-30
CZ302483B6 (cs) 2011-06-08
US20090239842A1 (en) 2009-09-24
AU784017B2 (en) 2006-01-12
MEP36708A (en) 2011-02-10
EA006937B1 (ru) 2006-06-30
TR200201270T2 (tr) 2002-12-23
PT1231920E (pt) 2007-03-30
HU229502B1 (en) 2014-01-28
ES2281359T3 (es) 2007-10-01
UA74563C2 (uk) 2006-01-16
US20080009476A1 (en) 2008-01-10
SK287343B6 (sk) 2010-07-07
RS50173B (sr) 2009-05-06
MXPA02004556A (es) 2004-09-10
MY130441A (en) 2007-06-29
HK1052303A1 (en) 2003-09-11
AU1138101A (en) 2001-05-30
PE20010826A1 (es) 2001-08-20
EE05395B1 (et) 2011-04-15
SI1231920T1 (sl) 2007-06-30
SK8302002A3 (en) 2002-09-10
JP2003514021A (ja) 2003-04-15
KR20020050273A (ko) 2002-06-26
YU33602A (sh) 2005-03-15

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