HUP0103346A2 - Készítmény és eljárás péniszerekció diszfunkció kezelésére - Google Patents
Készítmény és eljárás péniszerekció diszfunkció kezeléséreInfo
- Publication number
- HUP0103346A2 HUP0103346A2 HU0103346A HUP0103346A HUP0103346A2 HU P0103346 A2 HUP0103346 A2 HU P0103346A2 HU 0103346 A HU0103346 A HU 0103346A HU P0103346 A HUP0103346 A HU P0103346A HU P0103346 A2 HUP0103346 A2 HU P0103346A2
- Authority
- HU
- Hungary
- Prior art keywords
- composition
- mixture
- amount
- erectile dysfunction
- components
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 208000010228 Erectile Dysfunction Diseases 0.000 title 1
- 201000001881 impotence Diseases 0.000 title 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- 230000002708 enhancing effect Effects 0.000 abstract 2
- 230000035515 penetration Effects 0.000 abstract 2
- 230000003381 solubilizing effect Effects 0.000 abstract 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 abstract 1
- GMVPRGQOIOIIMI-UHFFFAOYSA-N (8R,11R,12R,13E,15S)-11,15-Dihydroxy-9-oxo-13-prostenoic acid Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CCCCCCC(O)=O GMVPRGQOIOIIMI-UHFFFAOYSA-N 0.000 abstract 1
- 150000000093 1,3-dioxanes Chemical class 0.000 abstract 1
- 125000006091 1,3-dioxolane group Chemical class 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 abstract 1
- 150000001241 acetals Chemical class 0.000 abstract 1
- 229960000711 alprostadil Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 229940041616 menthol Drugs 0.000 abstract 1
- 210000003899 penis Anatomy 0.000 abstract 1
- GMVPRGQOIOIIMI-DWKJAMRDSA-N prostaglandin E1 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O GMVPRGQOIOIIMI-DWKJAMRDSA-N 0.000 abstract 1
- XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 abstract 1
- 230000008719 thickening Effects 0.000 abstract 1
- 239000002562 thickening agent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gynecology & Obstetrics (AREA)
- Inorganic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Beans For Foods Or Fodder (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A találmány tárgya készítmény helyi alkalmazásra olyan személyekpéniszére, akiknek erre szükségük van, amely készítmény (a)prosztaglandin E1 farmakológiailag hatásos mennyiségét; (b) egy C6-C20szénhidrogéncsoporttal helyettesített 1,3-dioxánokból, 1,3-dioxolánokból és acetálokból álló csoportból kiválasztott,bőrbehatolást fokozó vegyület behatolást fokozó mennyiségét; (c) egygyógyszerészetileg hatékony vivőanyagot, amely (i) etilalkohol és víz,az (a) és (b) komponenseket szolubilizáló keveréke; (ii)izopropilalkohol és víz, az (a) és (b) komponenseket szolubilizálókeveréke; vagy (iii) egy olyan keverék lehet, amely az etilalkohol,izopropilalkohol közül legalább egyet és propilénglikolt tartalmaz; és(d) egy sűrítőszer sűrítő hatású mennyiségét; és adott esetben (e)mentol irritáció ellen hatékony mennyiségét tartalmazza. Ó
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1998/012284 WO1999065303A1 (en) | 1998-06-15 | 1998-06-15 | Composition and method for treating penile erectile dysfunction |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0103346A2 true HUP0103346A2 (hu) | 2002-01-28 |
HUP0103346A3 HUP0103346A3 (en) | 2004-06-28 |
HU224318B1 HU224318B1 (hu) | 2005-07-28 |
Family
ID=22267309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0103346A HU224318B1 (hu) | 1998-06-15 | 1998-06-15 | Készítmény és eljárás péniszerekció diszfunkció kezelésére |
Country Status (18)
Country | Link |
---|---|
US (1) | US5942545A (hu) |
EP (1) | EP1026947B1 (hu) |
JP (1) | JP3513764B2 (hu) |
KR (1) | KR20010022296A (hu) |
CN (1) | CN1206998C (hu) |
AT (1) | ATE209856T1 (hu) |
AU (1) | AU764437B2 (hu) |
BR (1) | BR9811797A (hu) |
CA (1) | CA2296373C (hu) |
DE (1) | DE69802838T2 (hu) |
DK (1) | DK1026947T3 (hu) |
ES (1) | ES2170503T3 (hu) |
HK (1) | HK1030133A1 (hu) |
HU (1) | HU224318B1 (hu) |
IL (1) | IL134191A0 (hu) |
NO (1) | NO20000157L (hu) |
PL (1) | PL189436B1 (hu) |
WO (1) | WO1999065303A1 (hu) |
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US6414028B1 (en) * | 1997-11-05 | 2002-07-02 | Nexmed Holdings, Inc. | Topical compositions containing prostaglandin E1 |
GR1003199B (el) | 1998-08-14 | 1999-09-01 | Χρηση της μισοπροστολης ή και της μισοπροστολης οξυ για την παρασκευη φαρμακευτικου προιοντος για τη θεραπευτικη αντιμετωπιση της σεξουαλικης δυσλειτουργιας στις γυναικες | |
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US5620980A (en) * | 1995-02-22 | 1997-04-15 | Macrochem Corporation | Method for treating hair loss |
US5583144A (en) * | 1995-02-24 | 1996-12-10 | Kral; John G. | Methods for treating erectile impotence |
US5968919A (en) * | 1997-10-16 | 1999-10-19 | Macrochem Corporation | Hormone replacement therapy drug formulations for topical application to the skin |
-
1997
- 1997-05-27 US US08/864,130 patent/US5942545A/en not_active Expired - Fee Related
-
1998
- 1998-06-15 CA CA002296373A patent/CA2296373C/en not_active Expired - Fee Related
- 1998-06-15 KR KR1020007000875A patent/KR20010022296A/ko active IP Right Grant
- 1998-06-15 AT AT98926585T patent/ATE209856T1/de not_active IP Right Cessation
- 1998-06-15 PL PL98338787A patent/PL189436B1/pl not_active IP Right Cessation
- 1998-06-15 DK DK98926585T patent/DK1026947T3/da active
- 1998-06-15 HU HU0103346A patent/HU224318B1/hu not_active IP Right Cessation
- 1998-06-15 JP JP52620299A patent/JP3513764B2/ja not_active Expired - Fee Related
- 1998-06-15 EP EP98926585A patent/EP1026947B1/en not_active Expired - Lifetime
- 1998-06-15 AU AU78387/98A patent/AU764437B2/en not_active Ceased
- 1998-06-15 ES ES98926585T patent/ES2170503T3/es not_active Expired - Lifetime
- 1998-06-15 CN CNB988081539A patent/CN1206998C/zh not_active Expired - Fee Related
- 1998-06-15 BR BR9811797-1A patent/BR9811797A/pt not_active Application Discontinuation
- 1998-06-15 WO PCT/US1998/012284 patent/WO1999065303A1/en active IP Right Grant
- 1998-06-15 IL IL13419198A patent/IL134191A0/xx not_active IP Right Cessation
- 1998-06-15 DE DE69802838T patent/DE69802838T2/de not_active Expired - Fee Related
-
2000
- 2000-01-12 NO NO20000157A patent/NO20000157L/no unknown
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2001
- 2001-02-15 HK HK01101101A patent/HK1030133A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US5942545A (en) | 1999-08-24 |
ES2170503T3 (es) | 2002-08-01 |
CN1206998C (zh) | 2005-06-22 |
DE69802838T2 (de) | 2002-06-27 |
AU7838798A (en) | 2000-01-05 |
JP2000511944A (ja) | 2000-09-12 |
WO1999065303A1 (en) | 1999-12-23 |
CN1267191A (zh) | 2000-09-20 |
NO20000157L (no) | 2000-02-09 |
DK1026947T3 (da) | 2002-04-02 |
CA2296373C (en) | 2003-08-12 |
ATE209856T1 (de) | 2001-12-15 |
JP3513764B2 (ja) | 2004-03-31 |
PL189436B1 (pl) | 2005-08-31 |
NO20000157D0 (no) | 2000-01-12 |
IL134191A0 (en) | 2001-04-30 |
HUP0103346A3 (en) | 2004-06-28 |
KR20010022296A (ko) | 2001-03-15 |
BR9811797A (pt) | 2000-09-26 |
HU224318B1 (hu) | 2005-07-28 |
HK1030133A1 (en) | 2001-04-27 |
AU764437B2 (en) | 2003-08-21 |
PL338787A1 (en) | 2000-11-20 |
EP1026947B1 (en) | 2001-12-05 |
EP1026947A1 (en) | 2000-08-16 |
CA2296373A1 (en) | 1999-12-23 |
DE69802838D1 (de) | 2002-01-17 |
EP1026947A4 (en) | 2000-10-25 |
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