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HUP0102425A3 - Imidazo pyridine derivatives which inhibit gastric acid secretion, process for producing them and pharmaceutical compositions containing them - Google Patents

Imidazo pyridine derivatives which inhibit gastric acid secretion, process for producing them and pharmaceutical compositions containing them

Info

Publication number
HUP0102425A3
HUP0102425A3 HU0102425A HUP0102425A HUP0102425A3 HU P0102425 A3 HUP0102425 A3 HU P0102425A3 HU 0102425 A HU0102425 A HU 0102425A HU P0102425 A HUP0102425 A HU P0102425A HU P0102425 A3 HUP0102425 A3 HU P0102425A3
Authority
HU
Hungary
Prior art keywords
producing
pharmaceutical compositions
compositions containing
gastric acid
acid secretion
Prior art date
Application number
HU0102425A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HUP0102425A2 publication Critical patent/HUP0102425A2/hu
Publication of HUP0102425A3 publication Critical patent/HUP0102425A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU0102425A 1998-04-29 1999-04-23 Imidazo pyridine derivatives which inhibit gastric acid secretion, process for producing them and pharmaceutical compositions containing them HUP0102425A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9801526A SE9801526D0 (sv) 1998-04-29 1998-04-29 New compounds
PCT/SE1999/000663 WO1999055706A1 (en) 1998-04-29 1999-04-23 Imidazo pyridine derivatives which inhibit gastric acid secretion

Publications (2)

Publication Number Publication Date
HUP0102425A2 HUP0102425A2 (hu) 2001-11-28
HUP0102425A3 true HUP0102425A3 (en) 2002-12-28

Family

ID=20411154

Family Applications (2)

Application Number Title Priority Date Filing Date
HU0102313A HUP0102313A3 (en) 1998-04-29 1999-04-23 Imidazo pyridine derivatives, process for their preparation pharmaceutical compositions containing the same and intermediates
HU0102425A HUP0102425A3 (en) 1998-04-29 1999-04-23 Imidazo pyridine derivatives which inhibit gastric acid secretion, process for producing them and pharmaceutical compositions containing them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU0102313A HUP0102313A3 (en) 1998-04-29 1999-04-23 Imidazo pyridine derivatives, process for their preparation pharmaceutical compositions containing the same and intermediates

Country Status (34)

Country Link
US (2) US6313137B1 (hu)
EP (4) EP1073657B1 (hu)
JP (2) JP3692034B2 (hu)
KR (3) KR100595805B1 (hu)
CN (2) CN1165535C (hu)
AR (2) AR015768A1 (hu)
AT (4) ATE312101T1 (hu)
AU (2) AU769108B2 (hu)
BR (2) BR9909995B1 (hu)
CA (2) CA2329921A1 (hu)
CZ (2) CZ292567B6 (hu)
DE (4) DE69927803T2 (hu)
DK (2) DK1073657T3 (hu)
EE (2) EE04676B1 (hu)
ES (2) ES2249913T3 (hu)
HK (5) HK1033457A1 (hu)
HU (2) HUP0102313A3 (hu)
ID (2) ID27530A (hu)
IL (4) IL139297A0 (hu)
IS (2) IS5683A (hu)
MY (2) MY121379A (hu)
NO (2) NO317262B1 (hu)
NZ (2) NZ507639A (hu)
PL (2) PL195000B1 (hu)
RU (2) RU2235725C2 (hu)
SA (2) SA99200065B1 (hu)
SE (1) SE9801526D0 (hu)
SI (1) SI1073656T1 (hu)
SK (2) SK285768B6 (hu)
TR (4) TR200003149T2 (hu)
TW (2) TWI250159B (hu)
UA (2) UA66846C2 (hu)
WO (2) WO1999055706A1 (hu)
ZA (2) ZA200005797B (hu)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
US6900324B2 (en) 2000-09-07 2005-05-31 Astrazeneca Ab Process for preparing a substituted imidazopyridine compound
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0100297D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100296D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100295D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
IL157075A0 (en) * 2001-02-13 2004-02-08 Astrazeneca Ab Novel modified release formulation
SK10982003A3 (sk) * 2001-03-08 2004-02-03 Astrazeneca Ab Nové použitie
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
CN100549011C (zh) 2002-09-19 2009-10-14 先灵公司 用作细胞周期蛋白依赖性激酶抑制剂的新颖咪唑并吡啶
NZ540504A (en) 2002-11-19 2007-12-21 Altana Pharma Ag 8-Substituted imidazopyridines for the treatment of gastrointestinal disorders
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
MXPA05009063A (es) * 2003-02-26 2005-12-12 Sugen Inc Compuestos de aminoheteroarilo como inhibidores de proteina cinasa.
PT1606261E (pt) 2003-03-10 2010-01-11 Nycomed Gmbh Novo processo para a preparação de roflumilast
SE525349C2 (sv) * 2003-06-23 2005-02-08 Volvo Penta Ab Utombordsdrev för båtar
SE0301905D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
SE0301903D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
SE0301904D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CN101361738A (zh) * 2003-11-03 2009-02-11 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2-a]吡啶衍生物
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
EP1711498A2 (en) * 2004-01-26 2006-10-18 Altana Pharma AG 1,2,4-triazolo¬1,5-a|pyridines as gastric acid secretion inhibitors
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20090291977A1 (en) * 2004-12-17 2009-11-26 Madoka Jinno Chromane Derivatives Useful As Acid Pump Antagonists
EP1861074B1 (en) 2005-03-16 2013-04-24 Takeda GmbH Taste masked dosage form containing roflumilast
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
AR056187A1 (es) * 2005-03-21 2007-09-26 S Bio Pte Ltd Derivados de imidazo[1,2-a)piridina: preparacion, composiciones farmaceuticas y uso para preparar medicamentos
JP2008536817A (ja) * 2005-03-24 2008-09-11 グラクソ グループ リミテッド 胃腸疾患の処置用医薬として有用なイミダゾ(1,2−a)ピリジン誘導体
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
NZ568654A (en) 2005-12-05 2012-02-24 Pfizer Prod Inc Method of treating abnormal cell growth
DK1963302T3 (da) 2005-12-05 2013-04-02 Pfizer Prod Inc Polymorfer af en C-MET/HGFR-inhibitor
RU2008137145A (ru) * 2006-03-17 2010-03-27 Раквалиа Фарма Инк. (Jp) Производные хромана
JP5571380B2 (ja) 2006-07-24 2014-08-13 ルミナス バイオサイエンシズ,インコーポレイテッド オストワルド熟成を減少させた水不溶性の医薬品物質の固体ナノ粒子処方物
WO2008059373A1 (en) * 2006-11-17 2008-05-22 Raqualia Pharma Inc. Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists
EP1974729A1 (en) * 2007-03-28 2008-10-01 Santhera Pharmaceuticals (Schweiz) AG Substituted imidazopyridine derivates as melanocortin- 4 receptor antagonists
WO2009122435A2 (en) * 2008-03-31 2009-10-08 Council Of Scientific & Industrial Research A simultaneous method for the preparation of a mixture of 3- acetoxy-17-acetamido-16-formyl-androst-5,17-diene and 3- acetoxy-2'-chloro-5-androsteno[17,16-b]pyridine
AU2014201644B2 (en) * 2008-12-03 2015-05-21 Cinclus Pharma Holding AB (publ) Imidazopyridine derivatives which inhibit the secretion of gastric acid
FI20086158A0 (fi) * 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
BRPI1013288A2 (pt) * 2009-07-09 2016-03-29 Raqualia Pharma Inc uso de um composto, método de composição farmacêutica para o tratamento de doenças em que a motilidade gastrointestinal anormal está envolvida, kit e embalagem comercial que compreende uma composição farmacêutica contendo o composto
BR112015030288B1 (pt) * 2013-06-25 2022-10-18 Ptc Therapeutics, Inc. Compostos e seu uso no tratamento de atrofia muscular espinhal
JP6616772B2 (ja) 2013-12-16 2019-12-04 アサナ・バイオサイエンシズ,リミテッド・ライアビリティ・カンパニー P2x3および/またはp2x2/3化合物ならびに方法
ES2692243T3 (es) * 2014-03-24 2018-11-30 Arqule, Inc. Proceso para preparar 3-(3-(4-(1-aminociclobutil)fenil)-5-fenil-3H-imidazo[4,5-b]piridin-2-il)piridin-2-amina
CN106279151A (zh) * 2015-06-26 2017-01-04 江苏太瑞生诺生物医药科技有限公司 5-(2-(8-((2,6-二甲基苄基)氨基)-2,3-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺基)乙氧基)-5-氧代戊酸的固体形式及其制备方法
KR101777971B1 (ko) 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
KR20190057569A (ko) 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
US11666888B2 (en) 2018-02-05 2023-06-06 Bio-Rad Laboratories, Inc. Chromatography resin having an anionic exchange-hydrophobic mixed mode ligand
JP7353295B2 (ja) * 2018-04-10 2023-09-29 バイエル・アクチエンゲゼルシヤフト 2,6-ジアルキルフェニル酢酸の製造方法
RU2732297C2 (ru) * 2018-11-14 2020-09-15 Общество с ограниченной ответственностью "Гурус БиоФарм" Производные нестероидных противовоспалительных средств
AU2020377451A1 (en) 2019-11-04 2022-05-26 Cinclus Pharma Holding AB Oral formulation of X842
AU2022381536A1 (en) 2021-11-05 2024-05-02 Cinclus Pharma Holding AB (publ) Polymorphs of the hydrochloride salt of linaprazan glurate
CN118414334A (zh) 2021-11-05 2024-07-30 辛克鲁斯制药控股有限公司 (Publ) 谷氨酸利那拉生甲磺酸盐的多晶型物
KR102496869B1 (ko) * 2022-07-29 2023-02-07 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법
WO2024149834A1 (en) 2023-01-11 2024-07-18 Cinclus Pharma Holding AB (publ) Polymorphs of the hydrobromide salt of linaprazan glurate
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WO2024161317A1 (ko) * 2023-02-01 2024-08-08 제일약품주식회사 약학적 제제, 이의 제조 방법, 및 정제용 조성물

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ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
EP0068378B1 (en) * 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (en) 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
GB8722488D0 (en) * 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound

Also Published As

Publication number Publication date
NZ507638A (en) 2003-10-31
CN1306533A (zh) 2001-08-01
DE69937077D1 (de) 2007-10-18
DE69928792T2 (de) 2006-07-20
PL195000B1 (pl) 2007-07-31
RU2238271C2 (ru) 2004-10-20
TWI250159B (en) 2006-03-01
DE69937076D1 (de) 2007-10-18
TR200102612T2 (tr) 2002-06-21
EE200000626A (et) 2002-04-15
SK285768B6 (sk) 2007-07-06
ID26819A (id) 2001-02-15
JP2002513024A (ja) 2002-05-08
SK14922000A3 (sk) 2001-06-11
ES2252975T3 (es) 2006-05-16
CA2329922C (en) 2006-04-11
DK1073657T3 (da) 2006-03-13
TR200003149T2 (tr) 2001-03-21
AU769108B2 (en) 2004-01-15
IL139297A (en) 2007-06-03
EP1073657A1 (en) 2001-02-07
NO318203B1 (no) 2005-02-14
IL139200A (en) 2010-04-29
EE04916B1 (et) 2007-10-15
ATE312101T1 (de) 2005-12-15
JP3692034B2 (ja) 2005-09-07
EP1491542A2 (en) 2004-12-29
ATE372340T1 (de) 2007-09-15
ZA200005796B (en) 2002-01-18
EP1073656B1 (en) 2005-10-19
SE9801526D0 (sv) 1998-04-29
EE04676B1 (et) 2006-08-15
MY121389A (en) 2006-01-28
ZA200005797B (en) 2002-01-18
NO20005451L (no) 2000-12-27
SA99200065B1 (ar) 2006-11-07
CN1174980C (zh) 2004-11-10
TW490466B (en) 2002-06-11
IL139200A0 (en) 2001-11-25
HK1033457A1 (en) 2001-08-31
PL343801A1 (en) 2001-09-10
BR9909996A (pt) 2000-12-26
IS5684A (is) 2000-10-25
EP1491543B1 (en) 2007-09-05
BR9909996B1 (pt) 2010-08-24
NO20005450L (no) 2000-12-22
NO317262B1 (no) 2004-09-27
JP2002513025A (ja) 2002-05-08
EP1073656A1 (en) 2001-02-07
BR9909995B1 (pt) 2010-07-13
CZ292567B6 (cs) 2003-10-15
JP3883383B2 (ja) 2007-02-21
BR9909995A (pt) 2000-12-26
HK1036984A1 (en) 2002-01-25
SI1073656T1 (sl) 2006-02-28
WO1999055706A1 (en) 1999-11-04
TR200003176T2 (tr) 2001-03-21
US6313136B1 (en) 2001-11-06
DE69928792D1 (de) 2006-01-12
CZ20003982A3 (cs) 2001-02-14
AR015769A1 (es) 2001-05-16
SK14912000A3 (sk) 2001-06-11
DE69927803T2 (de) 2006-07-06
KR100650472B1 (ko) 2006-11-28
CZ293977B6 (cs) 2004-09-15
RU2235725C2 (ru) 2004-09-10
CN1307577A (zh) 2001-08-08
EE200000664A (et) 2002-04-15
EP1491542B1 (en) 2007-09-05
KR20010043133A (ko) 2001-05-25
UA66846C2 (uk) 2004-06-15
HUP0102313A3 (en) 2002-10-28
ATE307130T1 (de) 2005-11-15
HUP0102313A2 (hu) 2001-12-28
ATE372339T1 (de) 2007-09-15
NO20005450D0 (no) 2000-10-27
HK1071139A1 (en) 2005-07-08
IS5683A (is) 2000-10-25
ES2249913T3 (es) 2006-04-01
EP1491542A3 (en) 2005-01-05
AU4300699A (en) 1999-11-16
CA2329921A1 (en) 1999-11-04
DK1073656T3 (da) 2006-01-16
IL139297A0 (en) 2001-11-25
WO1999055706A9 (en) 2000-03-16
ID27530A (id) 2001-04-12
DE69937077T2 (de) 2008-05-29
EP1073657B1 (en) 2005-12-07
CZ20003981A3 (cs) 2001-03-14
AU769190B2 (en) 2004-01-22
HK1036981A1 (en) 2002-01-25
NZ507639A (en) 2004-01-30
SA99200065A (ar) 2005-12-03
SA99200064B1 (ar) 2006-10-11
AR015768A1 (es) 2001-05-16
AU4300799A (en) 1999-11-16
HK1033317A1 (en) 2001-08-24
CN1165535C (zh) 2004-09-08
CA2329922A1 (en) 1999-11-04
KR100595805B1 (ko) 2006-07-03
US6313137B1 (en) 2001-11-06
UA67769C2 (uk) 2004-07-15
DE69937076T2 (de) 2008-05-29
MY121379A (en) 2006-01-28
KR100595806B1 (ko) 2006-07-03
EP1491543A1 (en) 2004-12-29
TR200102728T2 (tr) 2002-06-21
KR20010043134A (ko) 2001-05-25
NO20005451D0 (no) 2000-10-27
WO1999055705A1 (en) 1999-11-04
PL343797A1 (en) 2001-09-10
DE69927803D1 (de) 2006-03-02
HUP0102425A2 (hu) 2001-11-28
KR20050121760A (ko) 2005-12-27

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